Marzia Perluigi

9.6k total citations · 1 hit paper
126 papers, 7.7k citations indexed

About

Marzia Perluigi is a scholar working on Molecular Biology, Physiology and Public Health, Environmental and Occupational Health. According to data from OpenAlex, Marzia Perluigi has authored 126 papers receiving a total of 7.7k indexed citations (citations by other indexed papers that have themselves been cited), including 72 papers in Molecular Biology, 72 papers in Physiology and 21 papers in Public Health, Environmental and Occupational Health. Recurrent topics in Marzia Perluigi's work include Alzheimer's disease research and treatments (62 papers), Mitochondrial Function and Pathology (23 papers) and Down syndrome and intellectual disability research (20 papers). Marzia Perluigi is often cited by papers focused on Alzheimer's disease research and treatments (62 papers), Mitochondrial Function and Pathology (23 papers) and Down syndrome and intellectual disability research (20 papers). Marzia Perluigi collaborates with scholars based in Italy, United States and Chile. Marzia Perluigi's co-authors include D. Allan Butterfield, Fabio Di Domenico, Rukhsana Sultana, D. Allan Butterfield, Eugenio Barone, Raffaella Coccia, Antonella Tramutola, Chiara Lanzillotta, Elizabeth Head and William M. Pierce and has published in prestigious journals such as Physiological Reviews, PLoS ONE and Biochemical Journal.

In The Last Decade

Marzia Perluigi

121 papers receiving 7.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Oxidative damage in neurodegeneration: roles in the pathogenesis and progression of Alzheimer disease

2023 108 citations Marzia Perluigi, Fabio Di Domenico et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Marzia Perluigi Italy	53	3.8k	3.5k	971	834	696	126	7.7k
Fabio Di Domenico Italy	52	3.0k 0.8×	2.9k 0.8×	778 0.8×	752 0.9×	679 1.0×	117	6.5k
Giovanni Scapagnini Italy	52	3.8k 1.0×	2.4k 0.7×	822 0.8×	767 0.9×	408 0.6×	179	9.2k
Cesare Mancuso Italy	55	4.1k 1.1×	2.2k 0.6×	880 0.9×	857 1.0×	343 0.5×	102	8.4k
Alessandra Castegna Italy	38	4.5k 1.2×	2.9k 0.8×	723 0.7×	780 0.9×	518 0.7×	62	8.6k
Gemma Casadesús United States	55	3.8k 1.0×	4.7k 1.3×	1.2k 1.3×	1.4k 1.7×	719 1.0×	148	9.9k
George E. Barreto Colombia	61	4.2k 1.1×	2.8k 0.8×	1.1k 1.1×	2.2k 2.6×	949 1.4×	298	11.8k
William M. Pierce United States	54	5.2k 1.4×	3.2k 0.9×	888 0.9×	665 0.8×	377 0.5×	154	9.1k
Rudy J. Castellani United States	56	3.8k 1.0×	3.8k 1.1×	1.2k 1.2×	1.6k 2.0×	565 0.8×	170	9.2k
Gerald Münch Australia	60	3.3k 0.8×	4.1k 1.2×	1.3k 1.3×	1.9k 2.2×	328 0.5×	203	11.3k
Byung Pal Yu United States	47	3.3k 0.9×	2.5k 0.7×	416 0.4×	536 0.6×	875 1.3×	161	8.0k

Countries citing papers authored by Marzia Perluigi

Since Specialization

Citations

This map shows the geographic impact of Marzia Perluigi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Marzia Perluigi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Marzia Perluigi more than expected).

Fields of papers citing papers by Marzia Perluigi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Marzia Perluigi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Marzia Perluigi. The network helps show where Marzia Perluigi may publish in the future.

Co-authorship network of co-authors of Marzia Perluigi

This figure shows the co-authorship network connecting the top 25 collaborators of Marzia Perluigi. A scholar is included among the top collaborators of Marzia Perluigi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Marzia Perluigi. Marzia Perluigi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Tripodi, Farida, Antonella Tramutola, Marzia Perluigi, et al.. (2025). NF-κB-mediated cytokine secretion and glutamate metabolic reprogramming converge in breast cancer brain tropism. Cancer Letters. 630. 217907–217907.

Tramutola, Antonella, Fabio Di Domenico, Marzia Perluigi, & Eugenio Barone. (2025). Biliverdin reductase-A is a key modulator in insulin signaling and metabolism. Trends in Endocrinology and Metabolism. 1 indexed citations

Lanzillotta, Chiara, Viviana Greco, Federica Iavarone, et al.. (2025). Enhancing protein O-GlcNAcylation in down syndrome mice mitigates memory dysfunctions through the rescue of mitochondrial bioenergetics, stress responses and pathological markers. Redox Biology. 85. 103769–103769.

Esteve, Daniel, Chiara Lanzillotta, Antonella Tramutola, et al.. (2024). Altered mitochondrial unfolded protein response and protein quality control promote oxidative distress in down syndrome brain. Free Radical Biology and Medicine. 227. 80–93. 4 indexed citations

Tramutola, Antonella, et al.. (2024). Intranasal insulin administration reduces oxidative stress‐induced damage and improves mitochondrial bioenergetics in Alzheimer disease. Alzheimer s & Dementia. 20(S1). e087320–e087320.

Magnifico, Maria Chiara, Alessandro Paiardini, Alberto Macone, et al.. (2020). Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity. Cell Death and Disease. 11(11). 1012–1012. 16 indexed citations

Protto, Virginia, Antonella Tramutola, Marco Fabiani, et al.. (2020). Multiple Herpes Simplex Virus-1 (HSV-1) Reactivations Induce Protein Oxidative Damage in Mouse Brain: Novel Mechanisms for Alzheimer’s Disease Progression. Microorganisms. 8(7). 972–972. 29 indexed citations

Lanzillotta, Chiara, Antonella Tramutola, Antonio Francioso, et al.. (2020). The Dysregulation of OGT/OGA Cycle Mediates Tau and APP Neuropathology in Down Syndrome. Neurotherapeutics. 18(1). 340–363. 21 indexed citations

Lanzillotta, Chiara, Viviana Greco, Diletta Valentini, et al.. (2020). Proteomics Study of Peripheral Blood Mononuclear Cells in Down Syndrome Children. Antioxidants. 9(11). 1112–1112. 77 indexed citations

10.

Valenti, Daniela, Donatella Pietraforte, Fabio Di Domenico, et al.. (2020). The Anti-Diabetic Drug Metformin Rescues Aberrant Mitochondrial Activity and Restrains Oxidative Stress in a Female Mouse Model of Rett Syndrome. Journal of Clinical Medicine. 9(6). 1669–1669. 24 indexed citations

11.

Lanzillotta, Chiara, Chirag Vasavda, Solomon H. Snyder, et al.. (2020). BVR-A Deficiency Leads to Autophagy Impairment through the Dysregulation of AMPK/mTOR Axis in the Brain—Implications for Neurodegeneration. Antioxidants. 9(8). 671–671. 18 indexed citations

12.

Sharma, Nidhi, Antonella Tramutola, Chiara Lanzillotta, et al.. (2019). Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease. Neurobiology of Disease. 125. 176–189. 51 indexed citations

13.

Tramutola, Antonella, Fabio Di Domenico, Nidhi Sharma, et al.. (2018). Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: Implications for Alzheimer disease. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864(10). 3181–3194. 42 indexed citations

14.

Tramutola, Antonella, Chiara Lanzillotta, Eugenio Barone, et al.. (2018). Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome. Translational Neurodegeneration. 7(1). 28–28. 87 indexed citations

15.

Domenico, Fabio Di, Eugenio Barone, Marzia Perluigi, & D. Allan Butterfield. (2016). The Triangle of Death in Alzheimer's Disease Brain: The Aberrant Cross-Talk Among Energy Metabolism, Mammalian Target of Rapamycin Signaling, and Protein Homeostasis Revealed by Redox Proteomics. Antioxidants and Redox Signaling. 26(8). 364–387. 94 indexed citations

16.

Perluigi, Marzia, Eugenio Barone, Fabio Di Domenico, & D. Allan Butterfield. (2016). Aberrant protein phosphorylation in Alzheimer disease brain disturbs pro-survival and cell death pathways. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1862(10). 1871–1882. 68 indexed citations

17.

Triplett, Judy C., Antonella Tramutola, Aaron M. Swomley, et al.. (2015). Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1852(10). 2213–2224. 54 indexed citations

18.

Domenico, Fabio Di, Raffaella Coccia, M. Paul Murphy, et al.. (2013). Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: Redox proteomics analysis of human brain. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1832(8). 1249–1259. 113 indexed citations

19.

Barone, Eugenio, Fabio Di Domenico, Rukhsana Sultana, et al.. (2012). Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment. Free Radical Biology and Medicine. 52(11-12). 2292–2301. 106 indexed citations

20.

Mastromarino, Paola, Stefania Macchia, Vito Trinchieri, et al.. (2008). Effectiveness of Lactobacillus-containing vaginal tablets in the treatment of symptomatic bacterial vaginosis. Clinical Microbiology and Infection. 15(1). 67–74. 146 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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