Manu Setty

13.2k citations

31 papers · 6.0k indexed · 6 hit papers · h-index 21

Impact in

Immunology top 0.5%
- Immune cells in cancer
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
Cancer Research top 1%
- Cancer Genomics and Diagnostics

Papers in ⓘ

Molecular Biology 24
- Single-cell and spatial transcriptomics 15
- RNA Research and Splicing 4
- Genomics and Chromatin Dynamics 3
- CRISPR and Genetic Engineering 3
Immunology 9
- T-cell and B-cell Immunology 6
- Immune Cell Function and Interaction 4

Co-authors: Dana Pe’er (13 shared papers)Christina S. Leslie (10 shared papers)Linas Mažutis (4 shared papers)Vaidotas Kiseliovas (2 shared papers)Kristy Choi (2 shared papers)Eric C. Holland (3 shared papers)Jason T. Huse (2 shared papers)Robert L. Bowman (1 shared paper)
Journals: Nature Biotechnology (4 papers)Nature Methods (2 papers)Nature Medicine (2 papers)Nature Genetics (2 papers)Immunity (2 papers)
Partner nations: United States South Africa Canada

In The Last Decade

Manu Setty

31 papers receiving 5.9k citations

Hit Papers

6 papers align trajectories log scale

CellRank for directed single-cell fate mapping 2022 · 282 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2022 Nature Methods
2020 Nature Medicine
2019 Nature Biotechnology
2018 Cell
2016 Nature Biotechnology
2013 Nature Medicine

Peers

Countries citing papers authored by Manu Setty

Since Specialization

Citations

This map shows the geographic impact of Manu Setty's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Manu Setty with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Manu Setty more than expected).

Fields of papers citing papers by Manu Setty

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Manu Setty. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Manu Setty. The network helps show where Manu Setty may publish in the future.

Co-authors

The 25 scholars most cited alongside Manu Setty, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Manu Setty Line = papers co-authored together Manu Setty links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 31 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	CSF-1R inhibition alters macrophage polarization and blocks glioma progression Nature Medicine ·Stephanie M. Pyonteck, Leila Akkari, Alberto J. Schuhmacher, Robert L. Bowman, Lisa Sevenich, Daniela F. Quail, Oakley C. Olson, Marsha L. Quick, Jason T. Huse, Virginia Teijeiro, Manu Setty, Christina S. Leslie, Yoko Oei, Alicia Pedraza, Jianan Zhang, Cameron Brennan, James Sutton, Eric C. Holland, Dylan Daniel, Johanna A. Joyce Hit paper breakdown →	2013	1799
2	Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment Cell ·Elham Azizi, Ambrose Carr, George Plitas, Andrew Cornish, Catherine Konopacki, Sandhya Prabhakaran, Juozas Nainys, Kenmin Wu, Vaidotas Kiseliovas, Manu Setty, Kristy Choi, Rachel M. Fromme, Phuong Dao, Peter T. McKenney, Ruby Wasti, Krishna Kadaveru, Linas Mažutis, Alexander Y. Rudensky, Dana Pe’er Hit paper breakdown →	2018	1250
3	Wishbone identifies bifurcating developmental trajectories from single-cell data Nature Biotechnology ·Manu Setty, Michelle D. Tadmor, Shlomit Reich-Zeliger, Omer Angel, Tomer Meir Salame, Pooja Kathail, Kristy Choi, Sean C. Bendall, Nir Friedman, Dana Pe’er Hit paper breakdown →	2016	384
4	Characterization of cell fate probabilities in single-cell data with Palantir Nature Biotechnology ·Manu Setty, Vaidotas Kiseliovas, Jacob Levine, Adam Gayoso, Linas Mažutis, Dana Pe’er Hit paper breakdown →	2019	351
5	CellRank for directed single-cell fate mapping Nature Methods ·Marius Lange, Volker Bergen, Michal Klein, Manu Setty, Bernhard Reuter, Mostafa Bakhti, Heiko Lickert, Meshal Ansari, Janine Gote-Schniering, Herbert B. Schiller, Dana Pe’er, Fabian J. Theis Hit paper breakdown →	2022	282
6	Regenerative lineages and immune-mediated pruning in lung cancer metastasis Nature Medicine ·Ashley M. Laughney, Jing Hu, Nathaniel R. Campbell, Samuel F. Bakhoum, Manu Setty, Vincent‐Philippe Lavallée, Yubin Xie, Ignas Masilionis, Ambrose Carr, Sanjay Kottapalli, Viola Allaj, Marissa S. Mattar, Natasha Rekhtman, João B. Xavier, Linas Mažutis, John T. Poirier, Charles M. Rudin, Dana Pe’er, Joan Massagué Hit paper breakdown →	2020	251
7	The emergent landscape of the mouse gut endoderm at single-cell resolution Nature ·Sonja Nowotschin, Manu Setty, Ying-Yi Kuo, Vincent Liu, Vidur Garg, Roshan Sharma, Claire Simon, Néstor Saiz, Rui Gardner, Stéphane C. Boutet, Deanna M. Church, Pamela A. Hoodless, Anna‐Katerina Hadjantonakis, Dana Pe’er	2019	238
8	Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells Nature Biotechnology ·Eirini P. Papapetrou, Gabsang Lee, Nirav Malani, Manu Setty, Isabelle Rivière, Laxmi MS Tirunagari, Kyuichi Kadota, Shoshannah L. Roth, Patricia J. Giardina, Agnès Viale, Christina S. Leslie, Frederic D. Bushman, Lorenz Studer, Michel Sadelain	2010	217
9	A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL) Nature Genetics ·Konstantinos J. Mavrakis, Joni Van der Meulen, Andrew L. Wolfe, Xiaoping Liu, Evelien Mets, Tom Taghon, Aly A. Khan, Manu Setty, Pieter Rondou, Peter Vandenberghe, Éric Delabesse, Yves Benoît, Nicholas B Socci, Christina S. Leslie, Pieter Van Vlierberghe, Frank Speleman, Hans-Guido Wendel	2011	214
10	Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells Immunity ·Bertram Bengsch, Takuya Ohtani, Omar Khan, Manu Setty, Sasikanth Manne, Shaun O’Brien, Pier Federico Gherardini, Ramin S. Herati, Alexander C. Huang, Kyong‐Mi Chang, Evan W. Newell, Niels Bovenschen, Dana Pe’er, Steven Μ. Albelda, E. John Wherry	2018	183
11	Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer’s disease Nature Neuroscience ·Sudha R. Guttikonda, Lisa Sikkema, Jason Tchieu, Nathalie Saurat, Ryan Walsh, Oliver Harschnitz, Gabriele Ciceri, Marjolein A. M. Sneeboer, Linas Mažutis, Manu Setty, Paul Zumbo, Doron Betel, Lot D. de Witte, Dana Pe’er, Lorenz Studer	2021	145
12	BCL6 positively regulates AID and germinal center gene expression via repression of miR-155 The Journal of Experimental Medicine ·Katia Basso, Christof Schneider, Qiong Shen, Antony B. Holmes, Manu Setty, Christina S. Leslie, Riccardo Dalla‐Favera	2012	95
13	Inferring transcriptional and microRNA‐mediated regulatory programs in glioblastoma Molecular Systems Biology ·Manu Setty, Karim Y. Helmy, Aly A. Khan, Joachim Silber, Aaron Arvey, Frank Neezen, Phaedra Agius, Jason T. Huse, Eric C. Holland, Christina S. Leslie	2012	79
14	microRNA 28 controls cell proliferation and is down-regulated in B-cell lymphomas Proceedings of the National Academy of Sciences ·Christof Schneider, Manu Setty, Antony B. Holmes, Roy L. Maute, Christina S. Leslie, Lara Mussolin, Angelo Rosolen, Riccardo Dalla‐Favera, Katia Basso	2014	73
15	Negative Co-stimulation Constrains T Cell Differentiation by Imposing Boundaries on Possible Cell States Immunity ·Spencer C. Wei, Roshan Sharma, Nana-Ama A.S. Anang, Jacob Levine, Yang Zhao, James J. Mancuso, Manu Setty, Padmanee Sharma, Jing Wang, Dana Pe’er, James P. Allison	2019	68
16	SEACells infers transcriptional and epigenomic cellular states from single-cell genomics data Nature Biotechnology ·Sitara Persad, Zi-Ning Choo, Christine Dien, Noor Sohail, Ignas Masilionis, Ronan Chaligné, Tal Nawy, Chrysothemis C. Brown, Roshan Sharma, Itsik Pe’er, Manu Setty, Dana Pe’er	2023	66
17	Early enhancer establishment and regulatory locus complexity shape transcriptional programs in hematopoietic differentiation Nature Genetics ·Álvaro González, Manu Setty, Christina S. Leslie	2015	63
18	SeqGL Identifies Context-Dependent Binding Signals in Genome-Wide Regulatory Element Maps PLoS Computational Biology ·Manu Setty, Christina S. Leslie	2015	46
19	Single-Cell Transcriptomics Reveals Early Emergence of Liver Parenchymal and Non-parenchymal Cell Lineages Cell ·Jeremy Lotto, Sibyl Drissler, Rebecca Cullum, Wei Wei, Manu Setty, Erin M. Bell, Stéphane C. Boutet, Sonja Nowotschin, Ying-Yi Kuo, Vidur Garg, Dana Pe’er, Deanna M. Church, Anna‐Katerina Hadjantonakis, Pamela A. Hoodless	2020	45
20	CUT&Tag2for1: a modified method for simultaneous profiling of the accessible and silenced regulome in single cells Genome biology ·Derek H. Janssens, Dominik J. Otto, Michael P. Meers, Manu Setty, Kami Ahmad, Steven Henikoff	2022	37

About Manu Setty

Manu Setty is a scholar working on Molecular Biology, Immunology, Cancer Research, Biophysics and Pathology and Forensic Medicine, having authored 31 papers that have together received 6.0k indexed citations. Recurring topics across this work include Single-cell and spatial transcriptomics (15 papers), T-cell and B-cell Immunology (6 papers), Cell Image Analysis Techniques (4 papers), MicroRNA in disease regulation (4 papers), RNA Research and Splicing (4 papers), Immune Cell Function and Interaction (4 papers), Genomics and Chromatin Dynamics (3 papers) and CRISPR and Genetic Engineering (3 papers). The work is most often cited by research in Immunology (2.7k citations), Cancer Research (1.1k citations), Oncology (1.7k citations), Neurology (515 citations) and Genetics (555 citations). Manu Setty has collaborated with scholars based in United States, South Africa and Canada. Frequent co-authors include Dana Pe’er, Christina S. Leslie, Linas Mažutis, Vaidotas Kiseliovas, Kristy Choi, Eric C. Holland, Jason T. Huse, Robert L. Bowman, Alicia Pedraza and Yoko Oei. Their work appears in journals such as Nature Biotechnology, Nature Methods, Nature Medicine, Nature Genetics and Immunity.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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