James Sutton

4.6k citations

24 papers · 3.1k indexed · 2 hit papers · h-index 16

Impact in

Immunology top 1%
- Immune cells in cancer
- Phagocytosis and Immune Regulation
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
Neurology top 1%
- Neuroinflammation and Neurodegeneration Mechanisms

Papers in ⓘ

Neurology 3
- Neuroinflammation and Neurodegeneration Mechanisms 3
Organic Chemistry 10
- Synthesis and Catalytic Reactions 5
- Synthesis of β-Lactam Compounds 4
- Synthesis and Biological Evaluation 3

Co-authors: Robert L. Bowman (2 shared papers)Alberto J. Schuhmacher (2 shared papers)Johanna A. Joyce (3 shared papers)Eric C. Holland (2 shared papers)Marsha L. Quick (3 shared papers)Daniela F. Quail (3 shared papers)Leila Akkari (3 shared papers)Jason T. Huse (3 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (9 papers)Cancer Research (3 papers)Nature Medicine (1 paper)Tetrahedron Letters (1 paper)Journal of the American Chemical Society (1 paper)
Partner nations: United States Germany Switzerland

In The Last Decade

James Sutton

24 papers receiving 3.1k citations

Hit Papers

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The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas 2016 · 519 citations

Peers

Countries citing papers authored by James Sutton

Since Specialization

Citations

This map shows the geographic impact of James Sutton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James Sutton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James Sutton more than expected).

Fields of papers citing papers by James Sutton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James Sutton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James Sutton. The network helps show where James Sutton may publish in the future.

Co-authors

The 25 scholars most cited alongside James Sutton, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with James Sutton Line = papers co-authored together James Sutton links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 24 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	CSF-1R inhibition alters macrophage polarization and blocks glioma progression Nature Medicine ·Stephanie M. Pyonteck, Leila Akkari, Alberto J. Schuhmacher, Robert L. Bowman, Lisa Sevenich, Daniela F. Quail, Oakley C. Olson, Marsha L. Quick, Jason T. Huse, Virginia Teijeiro, Manu Setty, Christina S. Leslie, Yoko Oei, Alicia Pedraza, Jianan Zhang, Cameron Brennan, James Sutton, Eric C. Holland, Dylan Daniel, Johanna A. Joyce Hit paper breakdown →	2013	1799
2	The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas Science ·Daniela F. Quail, Robert L. Bowman, Leila Akkari, Marsha L. Quick, Alberto J. Schuhmacher, Jason T. Huse, Eric C. Holland, James Sutton, Johanna A. Joyce Hit paper breakdown →	2016	519
3	The Pinene Path to Taxanes. 6. A Concise Stereocontrolled Synthesis of Taxol Journal of the American Chemical Society ·Paul A. Wender, Neil F. Badham, Simon P. Conway, Paul E. Floreancig, Timothy E. Glass, Jonathan B. Houze, Nancy E. Krauss, Dae-Sung Lee, Daniel G. Marquess, P. Leo McGrane, Wei Meng, Michael G. Natchus, Anthony J. Shuker, James Sutton, Richard E. Taylor	1997	203
4	Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism eLife ·Huasong Lu, Yuhua Xue, Guoying Karen Yu, Carolina Arias, Julie Lin, Susan Fong, Michel Faure, Ben Weisburd, Xiao‐Dan Ji, Alexandre Mercier, James Sutton, Kunxin Luo, Zhenhai Gao, Qiang Zhou	2015	110
5	Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis Cell Reports ·Chintan Chhatbar, Claudia N. Detje, Elena Grabski, Katharina Borst, Julia Spanier, Luca Ghita, David A. Elliott, Marta Joana Costa Jordão, Nora Mueller, James Sutton, Chittappen Kandiyil Prajeeth, Viktoria Gudi, Michael A. Klein, Marco Prinz, Frank Bradke, Martin Stangel, Ulrich Kalinke	2018	83
6	Solid-phase synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors Bioorganic & Medicinal Chemistry Letters ·James Sutton, Scott A. Bolton, Malcolm E. Davis, Karen S. Hartl, Bruce L. Jacobson, Arvind Mathur, Martin L. Ogletree, William A. Slusarchyk, Robert Zahler, Steven M. Seiler, Gregory S. Bisacchi	2004	56
7	Synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors Bioorganic & Medicinal Chemistry Letters ·James Sutton, Scott A. Bolton, Karen S. Hartl, Ming‐Hsing Huang, G. A. JACOBS, Wei Meng, Martin L. Ogletree, Zulan Pi, William A. Schumacher, Steven M. Seiler, William A. Slusarchyk, Uwe Treuner, Robert Zahler, Guohua Zhao, Gregory S. Bisacchi	2002	53
8	Synthesis of potent and highly selective inhibitors of human tryptase Bioorganic & Medicinal Chemistry Letters ·William A. Slusarchyk, Scott A. Bolton, Karen S. Hartl, Ming‐Hsing Huang, G. A. JACOBS, Wei Meng, Martin L. Ogletree, Zulan Pi, William A. Schumacher, Steven M. Seiler, James Sutton, Uwe Treuner, Robert Zahler, Guohua Zhao, Gregory S. Bisacchi	2002	41
9	CDK9 inhibitors selectively target estrogen receptor-positive breast cancer cells through combined inhibition ofMYBandMCL-1expression Oncotarget ·Partha Mitra, Ren-Ming Yang, James Sutton, Robert G. Ramsay, Thomas J. Gonda	2016	38
10	CSF1R-dependent myeloid cells are required for NK‑mediated control of metastasis JCI Insight ·Michał Beffinger, Paulino Tallón de Lara, Sònia Tugues, Marijne Vermeer, Yannick Montagnolo, Isabel Ohs, Virginia Cecconi, Giulia Lucchiari, Aron Gagliardi, Nikola Misljencevic, James Sutton, Roman Spörri, Burkhard Becher, Anurag Gupta, Maries van den Broek	2018	37
11	Phenotypic and metabolic investigation of a CSF-1R kinase receptor inhibitor (BLZ945) and its pharmacologically active metabolite Xenobiotica ·Joel A. Krauser, Yi Jin, Markus Walles, Ulrike Pfaar, James Sutton, Marion Wiesmann, Daniel Graf, Veronique Pflimlin-Fritschy, Thierry Wolf, Gian Camenisch, Piet Swart	2014	29
12	Synthesis of potent and highly selective nonguanidine azetidinone inhibitors of human tryptase Bioorganic & Medicinal Chemistry Letters ·Gregory S. Bisacchi, William A. Slusarchyk, Scott A. Bolton, Karen S. Hartl, G. A. JACOBS, Arvind Mathur, Wei Meng, Martin L. Ogletree, Zulan Pi, James Sutton, Uwe Treuner, Robert Zahler, Guohua Zhao, Steven M. Seiler	2004	27
13	Investigation of Correlation Among Safety Biomarkers in Serum, Histopathological Examination, and Toxicogenomics International Journal of Toxicology ·Tao Wang, Maria Papoutsi, Marion Wiesmann, Marc F. DeCristofaro, Michael Keselica, Elizabeth Skuba, Robert H. Spaet, Judit Markovits, Armin Wolf, Pierre Moulin, François Pognan, Paul M. Vancutsem, Lew Petryk, James Sutton, Salah‐Dine Chibout, William M. Kluwe	2011	27
14	Molecular Basis of mRNA Cap Recognition by Influenza B Polymerase PB2 Subunit Journal of Biological Chemistry ·Lili Xie, Charles Wartchow, Steven Shia, Kyoko Uehara, Micah Steffek, Robert Warne, James Sutton, Gladys T. Muiru, Vincent H. J. Léonard, Dirksen E. Bussiere, Xiaolei Ma	2015	19
15	Synthesis and SAR of tetrahydropyrrolo[1,2-b][1,2,5]thiadiazol-2(3H)-one 1,1-dioxide analogues as highly potent selective androgen receptor modulators Bioorganic & Medicinal Chemistry Letters ·Mark C. Manfredi, Yingzhi Bi, Alexandra A. Nirschl, James Sutton, Ramakrishna Seethala, Rajasree Golla, Blake C. Beehler, Paul G. Sleph, Gary J. Grover, Jacek Ostrowski, Lawrence G. Hamann	2007	18
16	2-Aminothiazole based P2Y1 antagonists as novel antiplatelet agents Bioorganic & Medicinal Chemistry Letters ·Zulan Pi, James Sutton, John Lloyd, Ji Hua, Laura A. Price, Qimin Wu, Ming Chang, Joanna J. Zheng, Robert Rehfuss, Christine Huang, Ruth R. Wexler, Patrick Y. S. Lam	2013	16
17	Synthesis of potent and selective 2-azepanone inhibitors of human tryptase Bioorganic & Medicinal Chemistry Letters ·Guohua Zhao, Scott A. Bolton, Chet Kwon, Karen S. Hartl, Steven M. Seiler, William A. Slusarchyk, James Sutton, Gregory S. Bisacchi	2003	14
18	Discovery of nonbenzamidine factor VIIa inhibitors using a biaryl acid scaffold Bioorganic & Medicinal Chemistry Letters ·Scott A. Bolton, James Sutton, Rushith Anumula, Gregory S. Bisacchi, Bruce L. Jacobson, William A. Slusarchyk, Uwe Treuner, Shung Wu, Guohua Zhao, Zulan Pi, S. Sheriff, Rebecca A. Smirk, Sharon N. Bisaha, Daniel L. Cheney, Anzhi Wei, William A. Schumacher, Karen S. Hartl, Eddie Liu, Robert Zahler, Steven M. Seiler	2013	12
19	Toward the synthesis of taxol and its analogs: Incorporation of non-aromatic C-rings in the pinene pathway Tetrahedron Letters ·Paul A. Wender, Paul E. Floreancig, Timothy E. Glass, Michael G. Natchus, Anthony J. Shuker, James Sutton	1995	11
20	Abstract 3629: BLZ945, a selective c-fms (CSF-1R) kinase inhibitor for the suppression of tumor-induced osteolytic lesions in bone Cancer Research ·Marion Wiesmann, Dylan Daniel, Nancy Pryer, James Sutton, Victoria Sung, Tao Wang, Ursula Jeffry, Yoko Oei, Susan Kaufman, William Lenahan, Isabelle Lee, Kay Huh, Janet Sim	2010	9

About James Sutton

James Sutton is a scholar working on Neurology, Organic Chemistry, Pharmacology, Immunology and Oncology, having authored 24 papers that have together received 3.1k indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (6 papers), Synthesis and Catalytic Reactions (5 papers), Synthesis of β-Lactam Compounds (4 papers), Immune cells in cancer (4 papers), Synthesis and Biological Evaluation (3 papers), Neuroinflammation and Neurodegeneration Mechanisms (3 papers), Glioma Diagnosis and Treatment (3 papers) and Cancer Treatment and Pharmacology (2 papers). The work is most often cited by research in Immunology (1.9k citations), Neurology (544 citations), Genetics (666 citations), Oncology (1.0k citations) and Cancer Research (320 citations). James Sutton has collaborated with scholars based in United States, Germany and Switzerland. Frequent co-authors include Robert L. Bowman, Alberto J. Schuhmacher, Johanna A. Joyce, Eric C. Holland, Marsha L. Quick, Daniela F. Quail, Leila Akkari, Jason T. Huse, Yoko Oei and Dylan Daniel. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Cancer Research, Nature Medicine, Tetrahedron Letters and Journal of the American Chemical Society.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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