Manfred Jücker

4.4k total citations · 2 hit papers
104 papers, 3.2k citations indexed

About

Manfred Jücker is a scholar working on Molecular Biology, Oncology and Genetics. According to data from OpenAlex, Manfred Jücker has authored 104 papers receiving a total of 3.2k indexed citations (citations by other indexed papers that have themselves been cited), including 74 papers in Molecular Biology, 30 papers in Oncology and 17 papers in Genetics. Recurrent topics in Manfred Jücker's work include PI3K/AKT/mTOR signaling in cancer (47 papers), Chronic Lymphocytic Leukemia Research (13 papers) and Protein Kinase Regulation and GTPase Signaling (11 papers). Manfred Jücker is often cited by papers focused on PI3K/AKT/mTOR signaling in cancer (47 papers), Chronic Lymphocytic Leukemia Research (13 papers) and Protein Kinase Regulation and GTPase Signaling (11 papers). Manfred Jücker collaborates with scholars based in Germany, United States and Austria. Manfred Jücker's co-authors include N. V. Popova, Nico Hinz, Daniel J. Smit, Bianca T. Hofmann, Ricardo A. Feldman, Florian Ewald, Lingyu Tian, Hans Tesch, Nicole Grabinski and Björn Nashan and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nucleic Acids Research and Journal of Biological Chemistry.

In The Last Decade

Manfred Jücker

102 papers receiving 3.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Functional Role of Extracellular Matrix Proteins in Cancer

2022 154 citations N. V. Popova, Manfred Jücker profile →
The Role of PI3K/AKT/mTOR Signaling in Hepatocellular Carcinoma Metabolism

2023 145 citations Lingyu Tian, Daniel J. Smit et al. International Journal of Molecular Sciences profile →

Peers

Countries citing papers authored by Manfred Jücker

Since Specialization

Citations

This map shows the geographic impact of Manfred Jücker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Manfred Jücker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Manfred Jücker more than expected).

Fields of papers citing papers by Manfred Jücker

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Manfred Jücker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Manfred Jücker. The network helps show where Manfred Jücker may publish in the future.

Co-authorship network of co-authors of Manfred Jücker

This figure shows the co-authorship network connecting the top 25 collaborators of Manfred Jücker. A scholar is included among the top collaborators of Manfred Jücker based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Manfred Jücker. Manfred Jücker is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Proteomic Landscape of Colorectal Cancer Derived Liver Metastasis Reveals Three Distinct Phenotypes With Specific Signaling and Enhanced Survival 2025 ·Molecular & Cellular Proteomics ·(unknown), N. V. Popova, (unknown), Daniel J. Smit, (unknown), Matthew J. McKay, Thomas J. Hugh, Kerstin A. David, Hartmut Juhl, (unknown), Jens U. Marquardt, Björn Nashan, Hartmut Schlüter, Mark P. Molloy, Manfred Jücker	0
2	Functional Characterization of the SHIP1-Domains Regarding Their Contribution to Inositol 5-Phosphatase Activity 2025 ·Biomolecules ·(unknown), (unknown), Manfred Jücker	1
3	All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines 2024 ·International Journal of Molecular Sciences ·Lingyu Tian, Daniel J. Smit, N. V. Popova, Stefan Horn, Lis N. Velásquez, Samuel Huber, Manfred Jücker	5
4	Targeted hyperactivation of AKT through inhibition of ectopic expressed SHIP1 induces cell death in colon carcinoma cells and derived metastases 2023 ·Cellular Signalling ·(unknown), Michael Linnebacher, Andreas Block, (unknown), Manfred Jücker	2
5	SHIP1 Is Present but Strongly Downregulated in T-ALL, and after Restoration Suppresses Leukemia Growth in a T-ALL Xenotransplantation Mouse Model 2023 ·Cells ·(unknown), (unknown), (unknown), (unknown), Malte Kriegs, (unknown), Stefan Horn, Thomas Streichert, Martin A. Horstmann, Manfred Jücker	3
6	Generating Patient-Derived HCC Cell Lines Suitable for Predictive In Vitro and In Vivo Drug Screening by Orthotopic Transplantation 2023 ·Cells ·(unknown), (unknown), Kristoffer Riecken, (unknown), (unknown), Asmus Heumann, (unknown), Manfred Jücker, Boris Fehse, Udo Schumacher, Stefan Lüth, Janine Kah	2
7	JAK2-V617F is a negative regulation factor of SHIP1 protein and thus influences the AKT signaling pathway in patients with Myeloproliferative neoplasm (MPN) 2022 ·The International Journal of Biochemistry & Cell Biology ·(unknown), (unknown), Manfred Jücker, (unknown)	5
8	Investigation of the function of the PI3-Kinase / AKT signaling pathway for leukemogenesis and therapy of acute childhood lymphoblastic leukemia (ALL) 2022 ·Cellular Signalling ·(unknown), Astrid Grottke, (unknown), Manfred Jücker	7
9	Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia 2021 ·Nature Communications ·Veronika Ecker, (unknown), (unknown), (unknown), (unknown), Thomas Engleitner, Ingo Ringshausen, (unknown), Manfred Jücker, S. Wänninger, Thorsten Zenz, Clemens‐Martin Wendtner, Katrin Manske, Katja Steiger, Roland Rad, Markus Müschen, Jürgen Ruland, Maike Buchner	50
10	AKT1 and PTEN show the highest affinities among phosphoinositide binding proteins for the second messengers PtdIns(3,4,5)P3 and PtdIns(3,4)P2 2021 ·Biochemical and Biophysical Research Communications ·(unknown), Adelia Razeto, (unknown), (unknown), Johannes Kirchmair, Manfred Jücker	5
11	Differential regulation of extracellular matrix proteins in three recurrent liver metastases of a single patient with colorectal cancer 2020 ·Clinical & Experimental Metastasis ·(unknown), Marcus Wurlitzer, Daniel J. Smit, Florian Ewald, Malik Alawi, Michael Spohn, Daniela Indenbirken, (unknown), Kerstin A. David, Hartmut Juhl, Ronald Simon, Guido Sauter, Lutz Fischer, Jakob R. Izbicki, Mark P. Molloy, Björn Nashan, Hartmut Schlüter, Manfred Jücker	9
12	Analysis of the FLVR motif of SHIP1 and its importance for the protein stability of SH2 containing signaling proteins 2019 ·Cellular Signalling ·(unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), Christina de Bruyn Kops, Johannes Kirchmair, Marcus M. Nalaskowski, Manfred Jücker	9
13	Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects 2015 ·Clinical Cancer Research ·Jasmin Wellbrock, (unknown), Julian Köhler, Katharina Wagner, Hauke Stamm, Eik Vettorazzi, Gabi Vohwinkel, (unknown), (unknown), (unknown), Kristoffer Riecken, Sonja Loges, Felicitas Thol, Claudia Schubert, Michael Amling, Manfred Jücker, Carsten Bokemeyer, Michael Heuser, Jürgen Krauter, Walter Fiedler	86
14	H2S preconditioning of human adipose tissue-derived stem cells increases their efficacy in an in vitro model of cell therapy for simulated ischemia 2014 ·Life Sciences ·(unknown), (unknown), (unknown), (unknown), Astrid Grottke, Manfred Jücker, Udo Schumacher, Levente Kiss	14
15	Activation of PI3K/Akt signaling by n-terminal SH2 domain mutants of the p85α regulatory subunit of PI3K is enhanced by deletion of its c-terminal SH2 domain 2012 ·Cellular Signalling ·Bianca T. Hofmann, Manfred Jücker	28
16	Distinct functional roles of Akt isoforms for proliferation, survival, migration and EGF-mediated signalling in lung cancer derived disseminated tumor cells 2011 ·Cellular Signalling ·Nicole Grabinski, Kai Bartkowiak, Katharina Grupp, Burkhard Brandt, Klaus Pantel, Manfred Jücker	69
17	Mutations in the catalytic subunit of class IA PI3K confer leukemogenic potential to hematopoietic cells 2008 ·Oncogene ·Stefan Horn, Ulla Bergholz, Manfred Jücker, James A. McCubrey, Lorenz Trümper, Carol Stocking, Jörg Bäsecke	37
18	Restoration of SHIP activity in a human leukemia cell line downregulates constitutively activated phosphatidylinositol 3-kinase/Akt/GSK-3β signaling and leads to an increased transit time through the G1 phase of the cell cycle 2004 ·Leukemia ·Stefan Horn, Elmar Endl, Boris Fehse, Markus M. Weck, Georg W. Mayr, Manfred Jücker	62
19	Functional Specificity of Cytoplasmic and Transmembrane Tyrosine Kinases: Identification of 130- and 75-Kilodalton Substrates of c- fps/fes Tyrosine Kinase in Macrophages 1994 ·Molecular and Cellular Biology ·Liliana B. Areces, Persio Dello Sbarba, Manfred Jücker, E. Richard Stanley, Ricardo A. Feldman	24
20	Molecular analysis of Hodgkin's disease‐derived cell lines 1988 ·Hematological Oncology ·Hans Tesch, Manfred Jücker, Martin Falk, Georg W. Bornkamm, David B. Jones, Volker Diehl	13

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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