Luc Pilotte

4.3k citations

22 papers · 3.4k indexed · 1 hit paper · h-index 15

Co-authors: Benoı̂t J. Van den Eynde Vincent Stroobant Didier Colau Catherine Uyttenhove Ivan Théate Nicolas Parmentier Thierry Boon Pierre Larrieu
Topics: Tryptophan and brain disorders (18 papers)Stress Responses and Cortisol (5 papers)Immune cells in cancer (5 papers)
Cited by: Biological Psychiatry Behavioral Neuroscience Immunology
Journals: Proceedings of the National Academy of Sciences Nature MedicineSHILAP Revista de lepidopterología
Partner nations: Belgium France Switzerland

In The Last Decade

Luc Pilotte

21 papers receiving 3.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

2003 1.8k citations Catherine Uyttenhove, Luc Pilotte et al. Nature Medicine profile →

Peers

Countries citing papers authored by Luc Pilotte

Since Specialization

Citations

This map shows the geographic impact of Luc Pilotte's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Luc Pilotte with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Luc Pilotte more than expected).

Fields of papers citing papers by Luc Pilotte

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Luc Pilotte. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Luc Pilotte. The network helps show where Luc Pilotte may publish in the future.

Co-authorship network of co-authors of Luc Pilotte

This figure shows the co-authorship network connecting the top 25 collaborators of Luc Pilotte. A scholar is included among the top collaborators of Luc Pilotte based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Luc Pilotte. Luc Pilotte is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes 2023 ·Journal for ImmunoTherapy of Cancer ·(unknown),Pauline Pfänder,(unknown),Luc Pilotte,Vincent Stroobant,(unknown),Stefan Naulaerts,Quentin Spillier,Raphaël Frédérick,Etienne De Plaen,Christine Sers,Christiane A. Opitz,Benoı̂t J. Van den Eynde,Jingjing Zhu	53
2	IDO1 and TDO inhibitory evaluation of analogues of the marine pyrroloiminoquinone alkaloids: Wakayin and Tsitsikammamines 2021 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),(unknown),Vincent Stroobant,Luc Pilotte,Benoı̂t Van den Eynde,Frédéric Rodriguez,Evelyne Delfourne	4
3	Investigation of chalcogen bioisosteric replacement in a series of heterocyclic inhibitors of tryptophan 2,3-dioxygenase 2021 ·European Journal of Medicinal Chemistry ·(unknown),(unknown),Nicolas Dauguet,(unknown),Vincent Stroobant,Luc Pilotte,(unknown),Benoı̂t Van den Eynde,Raphaël Frédérick	8
4	TGFβ1 neutralization displays therapeutic efficacy through both an immunomodulatory and a non-immune tumor-intrinsic mechanism 2021 ·Journal for ImmunoTherapy of Cancer ·Stefania Canè,Jacques Van Snick,Catherine Uyttenhove,Luc Pilotte,Benoı̂t J. Van den Eynde	18
5	Rational Design of Original Fused-Cycle Selective Inhibitors of Tryptophan 2,3-Dioxygenase 2021 ·Journal of Medicinal Chemistry ·(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Luc Pilotte,Vincent Stroobant,Benoı̂t Van den Eynde,Raphaël Frédérick	14
6	Tryptophanemia is controlled by a tryptophan-sensing mechanism ubiquitinating tryptophan 2,3-dioxygenase 2021 ·Proceedings of the National Academy of Sciences ·(unknown),Vincent Stroobant,(unknown),Mads Gyrd‐Hansen,Luc Pilotte,Nathalie Vigneron,Etienne De Plaen,Benoı̂t J. Van den Eynde	9
7	Inhibition of Tryptophan-Dioxygenase Activity Increases the Antitumor Efficacy of Immune Checkpoint Inhibitors 2019 ·Cancer Immunology Research ·(unknown),Stefano Crosignani,(unknown),(unknown),Luc Pilotte,Vincent Stroobant,(unknown),Grégory Driessens,Benoı̂t J. Van den Eynde	55
8	Induction of tryptophan 2,3-dioxygenase expression in human monocytic leukemia/lymphoma cell lines THP-1 and U937 2019 ·SHILAP Revista de lepidopterología ·(unknown),Luc Pilotte,Vincent Stroobant,Benoı̂t J. Van den Eynde	7
9	Constitutive IDO1 Expression in Human Tumors Is Driven by Cyclooxygenase-2 and Mediates Intrinsic Immune Resistance 2017 ·Cancer Immunology Research ·Marc Hennequart,Luc Pilotte,Stefania Canè,(unknown),Vincent Stroobant,Etienne De Plaen,Benoı̂t J. Van den Eynde	137
10	Apolipoproteins L control cell death triggered by TLR3/TRIF signaling in dendritic cells 2016 ·European Journal of Immunology ·Sophie Uzureau,(unknown),(unknown),Pierrick Uzureau,(unknown),Luc Pilotte,Daniel Monteyne,(unknown),Benoît Vanhollebeke,Benoı̂t Van den Eynde,David Pérez‐Morga,Muriel Moser,Etienne Pays	37
11	Extensive Profiling of the Expression of the Indoleamine 2,3-Dioxygenase 1 Protein in Normal and Tumoral Human Tissues 2014 ·Cancer Immunology Research ·Ivan Théate,Nicolas van Baren,Luc Pilotte,Pierre Moulin,Pierre Larrieu,Jean‐Christophe Renauld,Caroline Hervé,Ilse Gutierrez-Roelens,Étienne Marbaix,Christine Sempoux,Benoı̂t J. Van den Eynde	284
12	Detailed analysis and follow-up studies of a high-throughput screening for indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors 2014 ·European Journal of Medicinal Chemistry ·Ute F. Röhrig,Somi Reddy Majjigapu,Marc Chambon,(unknown),Luc Pilotte,Didier Colau,Benoı̂t J. Van den Eynde,Gerardo Turcatti,Pierre Vogel,Vincent Zoete,Olivier Michielin	65
13	Indoleamine 2,3-dioxygenase inhibitory activity of derivatives of marine alkaloid tsitsikammamine A 2012 ·Bioorganic & Medicinal Chemistry Letters ·Eduard Dolušić,Pierre Larrieu,(unknown),(unknown),Arnaud Rives,Sébastien Blanc,Thierry Ferain,Luc Pilotte,Vincent Stroobant,Johan Wouters,Benoı̂t Van den Eynde,Bernard Masereel,Evelyne Delfourne,Raphaël Frédérick	27
14	Rational Design of 4-Aryl-1,2,3-Triazoles for Indoleamine 2,3-Dioxygenase 1 Inhibition 2012 ·Journal of Medicinal Chemistry ·Ute F. Röhrig,Somi Reddy Majjigapu,Aurélien Grosdidier,(unknown),Vincent Stroobant,Luc Pilotte,Didier Colau,Pierre Vogel,Benoı̂t J. Van den Eynde,Vincent Zoete,Olivier Michielin	148
15	Minimal Tolerance to a Tumor Antigen Encoded by a Cancer-Germline Gene 2011 ·The Journal of Immunology ·Ivo J. Huijbers,Saïdi M. Soudja,Catherine Uyttenhove,Michel Buferne,Else-Marit Inderberg-Suso,Didier Colau,Luc Pilotte,(unknown),Patrick Chomez,Francis Brasseur,Anne‐Marie Schmitt‐Verhulst,Benoı̂t J. Van den Eynde	26
16	Discovery and preliminary SARs of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors 2011 ·European Journal of Medicinal Chemistry ·Eduard Dolušić,Pierre Larrieu,Sébastien Blanc,(unknown),(unknown),(unknown),(unknown),Vincent Stroobant,Luc Pilotte,Didier Colau,Thierry Ferain,(unknown),Moreno Galleni,Jean‐Marie Frère,Bernard Masereel,Benoı̂t Van den Eynde,Johan Wouters,Raphaël Frédérick	50
17	Tryptophan 2,3-Dioxygenase (TDO) Inhibitors. 3-(2-(Pyridyl)ethenyl)indoles as Potential Anticancer Immunomodulators 2011 ·Journal of Medicinal Chemistry ·Eduard Dolušić,Pierre Larrieu,(unknown),Vincent Stroobant,Luc Pilotte,Didier Colau,Lionel Pochet,Benoı̂t Van den Eynde,Bernard Masereel,Johan Wouters,Raphaël Frédérick	155
18	Indol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors 2010 ·Bioorganic & Medicinal Chemistry ·Eduard Dolušić,Pierre Larrieu,Sébastien Blanc,(unknown),Bernadette Norberg,(unknown),(unknown),Vincent Stroobant,Luc Pilotte,Didier Colau,Thierry Ferain,(unknown),(unknown),(unknown),Bernard Masereel,Benoı̂t Van den Eynde,Johan Wouters,Raphaël Frédérick	34
19	Tumoral immune resistance based on tryptophan degradation by indoleamine 2,3-dioxygenase 2007 ·International Congress Series ·Benoı̂t J. Van den Eynde,Ivan Théate,Catherine Uyttenhove,Didier Colau,Luc Pilotte,Vincent Stroobant	3
20	Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenasebreakdown → 2003 ·Nature Medicine ·Catherine Uyttenhove,Luc Pilotte,Ivan Théate,Vincent Stroobant,Didier Colau,Nicolas Parmentier,Thierry Boon,Benoı̂t J. Van den Eynde	1807

About Luc Pilotte

Luc Pilotte is a scholar working on Biological Psychiatry, Behavioral Neuroscience and Immunology, having authored 22 papers that have together received 3.4k indexed citations. Recurring topics across this work include Tryptophan and brain disorders (18 papers), Stress Responses and Cortisol (5 papers) and Immune cells in cancer (5 papers). The work is most often cited by research in Biological Psychiatry (1.7k citations), Behavioral Neuroscience (532 citations) and Immunology (1.3k citations). Luc Pilotte has collaborated with scholars based in Belgium, France and Switzerland. Frequent co-authors include Benoı̂t J. Van den Eynde, Vincent Stroobant, Didier Colau, Catherine Uyttenhove, Ivan Théate, Nicolas Parmentier, Thierry Boon, Pierre Larrieu, Raphaël Frédérick and Etienne De Plaen. Their work appears in journals such as Proceedings of the National Academy of Sciences, Nature Medicine and SHILAP Revista de lepidopterología.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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