Luc Pilotte

4.3k total citations · 1 hit paper
22 papers, 3.4k citations indexed

About

Luc Pilotte is a scholar working on Biological Psychiatry, Molecular Biology and Immunology. According to data from OpenAlex, Luc Pilotte has authored 22 papers receiving a total of 3.4k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Biological Psychiatry, 11 papers in Molecular Biology and 8 papers in Immunology. Recurrent topics in Luc Pilotte's work include Tryptophan and brain disorders (18 papers), Stress Responses and Cortisol (5 papers) and Immune cells in cancer (5 papers). Luc Pilotte is often cited by papers focused on Tryptophan and brain disorders (18 papers), Stress Responses and Cortisol (5 papers) and Immune cells in cancer (5 papers). Luc Pilotte collaborates with scholars based in Belgium, France and Switzerland. Luc Pilotte's co-authors include Benoı̂t J. Van den Eynde, Vincent Stroobant, Didier Colau, Catherine Uyttenhove, Ivan Théate, Nicolas Parmentier, Thierry Boon, Pierre Larrieu, Raphaël Frédérick and Etienne De Plaen and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nature Medicine and SHILAP Revista de lepidopterología.

In The Last Decade

Luc Pilotte

21 papers receiving 3.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

2003 1.8k citations Catherine Uyttenhove, Luc Pilotte et al. Nature Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Luc Pilotte Belgium	15	1.7k	1.3k	1.0k	872	624	22	3.4k
Nicolas Parmentier Belgium	7	845 0.5×	1.0k 0.8×	793 0.8×	785 0.9×	261 0.4×	10	2.2k
Martina Ott United States	24	980 0.6×	1.5k 1.2×	1.3k 1.3×	933 1.1×	277 0.4×	42	3.8k
Erika Sutanto‐Ward United States	14	876 0.5×	597 0.5×	544 0.5×	414 0.5×	282 0.5×	22	1.6k
Lisa D. Laury‐Kleintop United States	19	739 0.4×	581 0.5×	610 0.6×	392 0.4×	273 0.4×	36	1.8k
William P. Malachowski United States	19	740 0.4×	382 0.3×	714 0.7×	287 0.3×	320 0.5×	34	1.8k
Alban Bessede France	25	627 0.4×	517 0.4×	733 0.7×	807 0.9×	208 0.3×	59	2.3k
Pierre Larrieu France	11	726 0.4×	362 0.3×	535 0.5×	221 0.3×	288 0.5×	16	1.3k
Jun Wei China	31	243 0.1×	453 0.4×	1.8k 1.7×	501 0.6×	185 0.3×	169	3.6k
Guillermo N. Armaiz-Peña United States	27	86 0.1×	254 0.2×	1.3k 1.2×	750 0.9×	736 1.2×	63	2.8k
David S. Duch United States	25	311 0.2×	244 0.2×	1.2k 1.1×	263 0.3×	85 0.1×	62	2.6k

Countries citing papers authored by Luc Pilotte

Since Specialization

Citations

This map shows the geographic impact of Luc Pilotte's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Luc Pilotte with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Luc Pilotte more than expected).

Fields of papers citing papers by Luc Pilotte

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Luc Pilotte. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Luc Pilotte. The network helps show where Luc Pilotte may publish in the future.

Co-authorship network of co-authors of Luc Pilotte

This figure shows the co-authorship network connecting the top 25 collaborators of Luc Pilotte. A scholar is included among the top collaborators of Luc Pilotte based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Luc Pilotte. Luc Pilotte is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Pfänder, Pauline, Luc Pilotte, Vincent Stroobant, et al.. (2023). Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes. Journal for ImmunoTherapy of Cancer. 11(6). e006728–e006728. 53 indexed citations

Stroobant, Vincent, et al.. (2021). IDO1 and TDO inhibitory evaluation of analogues of the marine pyrroloiminoquinone alkaloids: Wakayin and Tsitsikammamines. Bioorganic & Medicinal Chemistry Letters. 40. 127910–127910. 4 indexed citations

Dauguet, Nicolas, et al.. (2021). Investigation of chalcogen bioisosteric replacement in a series of heterocyclic inhibitors of tryptophan 2,3-dioxygenase. European Journal of Medicinal Chemistry. 227. 113892–113892. 8 indexed citations

Canè, Stefania, Jacques Van Snick, Catherine Uyttenhove, Luc Pilotte, & Benoı̂t J. Van den Eynde. (2021). TGFβ1 neutralization displays therapeutic efficacy through both an immunomodulatory and a non-immune tumor-intrinsic mechanism. Journal for ImmunoTherapy of Cancer. 9(2). e001798–e001798. 18 indexed citations

Pilotte, Luc, et al.. (2021). Rational Design of Original Fused-Cycle Selective Inhibitors of Tryptophan 2,3-Dioxygenase. Journal of Medicinal Chemistry. 64(15). 10967–10980. 14 indexed citations

Stroobant, Vincent, Mads Gyrd‐Hansen, Luc Pilotte, et al.. (2021). Tryptophanemia is controlled by a tryptophan-sensing mechanism ubiquitinating tryptophan 2,3-dioxygenase. Proceedings of the National Academy of Sciences. 118(23). 9 indexed citations

Crosignani, Stefano, et al.. (2019). Inhibition of Tryptophan-Dioxygenase Activity Increases the Antitumor Efficacy of Immune Checkpoint Inhibitors. Cancer Immunology Research. 8(1). 32–45. 55 indexed citations

Pilotte, Luc, et al.. (2019). Induction of tryptophan 2,3-dioxygenase expression in human monocytic leukemia/lymphoma cell lines THP-1 and U937. SHILAP Revista de lepidopterología. 12. 519686936–519686936. 7 indexed citations

Hennequart, Marc, Luc Pilotte, Stefania Canè, et al.. (2017). Constitutive IDO1 Expression in Human Tumors Is Driven by Cyclooxygenase-2 and Mediates Intrinsic Immune Resistance. Cancer Immunology Research. 5(8). 695–709. 137 indexed citations

10.

Uzureau, Sophie, Pierrick Uzureau, Luc Pilotte, et al.. (2016). Apolipoproteins L control cell death triggered by TLR3/TRIF signaling in dendritic cells. European Journal of Immunology. 46(8). 1854–1866. 37 indexed citations

11.

Théate, Ivan, Nicolas van Baren, Luc Pilotte, et al.. (2014). Extensive Profiling of the Expression of the Indoleamine 2,3-Dioxygenase 1 Protein in Normal and Tumoral Human Tissues. Cancer Immunology Research. 3(2). 161–172. 284 indexed citations

12.

Röhrig, Ute F., Somi Reddy Majjigapu, Marc Chambon, et al.. (2014). Detailed analysis and follow-up studies of a high-throughput screening for indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors. European Journal of Medicinal Chemistry. 84. 284–301. 65 indexed citations

13.

Dolušić, Eduard, Pierre Larrieu, Arnaud Rives, et al.. (2012). Indoleamine 2,3-dioxygenase inhibitory activity of derivatives of marine alkaloid tsitsikammamine A. Bioorganic & Medicinal Chemistry Letters. 23(1). 47–54. 27 indexed citations

14.

Röhrig, Ute F., Somi Reddy Majjigapu, Aurélien Grosdidier, et al.. (2012). Rational Design of 4-Aryl-1,2,3-Triazoles for Indoleamine 2,3-Dioxygenase 1 Inhibition. Journal of Medicinal Chemistry. 55(11). 5270–5290. 148 indexed citations

15.

Huijbers, Ivo J., Saïdi M. Soudja, Catherine Uyttenhove, et al.. (2011). Minimal Tolerance to a Tumor Antigen Encoded by a Cancer-Germline Gene. The Journal of Immunology. 188(1). 111–121. 26 indexed citations

16.

Dolušić, Eduard, Pierre Larrieu, Sébastien Blanc, et al.. (2011). Discovery and preliminary SARs of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors. European Journal of Medicinal Chemistry. 46(7). 3058–3065. 50 indexed citations

17.

Dolušić, Eduard, Pierre Larrieu, Vincent Stroobant, et al.. (2011). Tryptophan 2,3-Dioxygenase (TDO) Inhibitors. 3-(2-(Pyridyl)ethenyl)indoles as Potential Anticancer Immunomodulators. Journal of Medicinal Chemistry. 54(15). 5320–5334. 155 indexed citations

18.

Dolušić, Eduard, Pierre Larrieu, Sébastien Blanc, et al.. (2010). Indol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors. Bioorganic & Medicinal Chemistry. 19(4). 1550–1561. 34 indexed citations

19.

Eynde, Benoı̂t J. Van den, Ivan Théate, Catherine Uyttenhove, et al.. (2007). Tumoral immune resistance based on tryptophan degradation by indoleamine 2,3-dioxygenase. International Congress Series. 1304. 274–277. 3 indexed citations

20.

Uyttenhove, Catherine, Luc Pilotte, Ivan Théate, et al.. (2003). Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase. Nature Medicine. 9(10). 1269–1274. 1807 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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