Lorne J. Hofseth

11.4k total citations · 2 hit papers
97 papers, 8.7k citations indexed

About

Lorne J. Hofseth is a scholar working on Molecular Biology, Oncology and Pathology and Forensic Medicine. According to data from OpenAlex, Lorne J. Hofseth has authored 97 papers receiving a total of 8.7k indexed citations (citations by other indexed papers that have themselves been cited), including 45 papers in Molecular Biology, 28 papers in Oncology and 17 papers in Pathology and Forensic Medicine. Recurrent topics in Lorne J. Hofseth's work include Ginseng Biological Effects and Applications (15 papers), Pharmacological Effects of Natural Compounds (10 papers) and Genomics, phytochemicals, and oxidative stress (9 papers). Lorne J. Hofseth is often cited by papers focused on Ginseng Biological Effects and Applications (15 papers), Pharmacological Effects of Natural Compounds (10 papers) and Genomics, phytochemicals, and oxidative stress (9 papers). Lorne J. Hofseth collaborates with scholars based in United States, Canada and China. Lorne J. Hofseth's co-authors include Curtis C. Harris, S. Perwez Hussain, Prakash Nagarkatti, Ying Lei, Paul R. Thompson, Alexander A. Chumanevich, Erin E. Witalison, Michael J. Wargovich, Narendra P. Singh and Xin Wei Wang and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Lorne J. Hofseth

95 papers receiving 8.5k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Radical causes of cancer

2003 1.3k citations S. Perwez Hussain, Lorne J. Hofseth et al. profile →
Early-onset colorectal cancer: initial clues and current views

2020 269 citations Lorne J. Hofseth, James R. Hébert et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Lorne J. Hofseth United States	48	3.9k	2.2k	1.7k	1.3k	1.0k	97	8.7k
Kazuo Umezawa Japan	51	5.3k 1.3×	2.1k 0.9×	2.4k 1.4×	2.1k 1.6×	632 0.6×	425	11.0k
S. Perwez Hussain United States	49	5.5k 1.4×	3.8k 1.7×	3.0k 1.7×	1.4k 1.1×	858 0.8×	100	11.5k
Matthew R. Young United States	52	4.0k 1.0×	2.5k 1.1×	1.4k 0.8×	2.4k 1.9×	636 0.6×	228	9.2k
Mary Pat Moyer United States	57	4.4k 1.1×	1.4k 0.6×	963 0.6×	790 0.6×	671 0.7×	181	8.6k
Muthusamy Thangaraju United States	47	5.7k 1.5×	1.4k 0.7×	1.3k 0.8×	1.2k 1.0×	818 0.8×	110	8.8k
Frank Arfuso Australia	56	5.5k 1.4×	1.8k 0.8×	1.7k 1.0×	754 0.6×	480 0.5×	131	10.2k
John DiGiovanni United States	56	6.6k 1.7×	3.5k 1.6×	3.1k 1.8×	2.2k 1.7×	734 0.7×	322	12.6k
Amir Avan Iran	50	4.6k 1.2×	1.9k 0.8×	2.4k 1.4×	798 0.6×	505 0.5×	344	9.1k
Kei Nakachi Japan	47	4.0k 1.0×	1.9k 0.9×	1.5k 0.9×	1.2k 1.0×	943 0.9×	155	9.3k
Rolf Schulte‐Hermann Austria	57	6.1k 1.5×	2.5k 1.1×	2.5k 1.4×	852 0.7×	603 0.6×	202	12.2k

Countries citing papers authored by Lorne J. Hofseth

Since Specialization

Citations

This map shows the geographic impact of Lorne J. Hofseth's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lorne J. Hofseth with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lorne J. Hofseth more than expected).

Fields of papers citing papers by Lorne J. Hofseth

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lorne J. Hofseth. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lorne J. Hofseth. The network helps show where Lorne J. Hofseth may publish in the future.

Co-authorship network of co-authors of Lorne J. Hofseth

This figure shows the co-authorship network connecting the top 25 collaborators of Lorne J. Hofseth. A scholar is included among the top collaborators of Lorne J. Hofseth based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lorne J. Hofseth. Lorne J. Hofseth is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

VanderVeen, Brandon N., Thomas D. Cardaci, Christoph Unger, et al.. (2025). Cannabis improves metabolic dysfunction and macrophage signatures in obese mice. American Journal of Physiology-Cell Physiology. 329(4). C1316–C1331.

Hofseth, Lorne J., et al.. (2024). Allura Red AC is a xenobiotic. Is it also a carcinogen?. Carcinogenesis. 45(10). 711–720. 10 indexed citations

Chumanevich, Alexander A., Alexander A. Chumanevich, Ioulia Chatzistamou, et al.. (2023). The synthetic food dye, Red 40, causes DNA damage, causes colonic inflammation, and impacts the microbiome in mice. Toxicology Reports. 11. 221–232. 24 indexed citations

Hofseth, Lorne J.. (2017). Getting rigorous with scientific rigor. Carcinogenesis. 39(1). 21–25. 27 indexed citations

Poudyal, Deepak, Phuong Mai Le, Tia Davis, et al.. (2012). A Hexane Fraction of American Ginseng Suppresses Mouse Colitis and Associated Colon Cancer: Anti-inflammatory and Proapoptotic Mechanisms. Cancer Prevention Research. 5(4). 685–696. 28 indexed citations

Sohn, Jane J., Aaron J. Schetter, Harris G. Yfantis, et al.. (2012). Macrophages, Nitric Oxide and microRNAs Are Associated with DNA Damage Response Pathway and Senescence in Inflammatory Bowel Disease. PLoS ONE. 7(9). e44156–e44156. 56 indexed citations

Singh, Narendra P., Udai P. Singh, Venkatesh L. Hegde, et al.. (2011). Resveratrol (trans‐3,5,4′‐trihydroxystilbene) suppresses EL4 tumor growth by induction of apoptosis involving reciprocal regulation of SIRT1 and NF‐κB. Molecular Nutrition & Food Research. 55(8). 1207–1218. 36 indexed citations

Cui, Xiangli, Jin Yu, Anne B. Hofseth, et al.. (2010). Resveratrol Suppresses Colitis and Colon Cancer Associated with Colitis. Cancer Prevention Research. 3(4). 549–559. 179 indexed citations

Yu, Jin, Anne B. Hofseth, Xiangli Cui, et al.. (2010). American Ginseng Suppresses Colitis through p53-Mediated Apoptosis of Inflammatory Cells. Cancer Prevention Research. 3(3). 339–347. 55 indexed citations

10.

Lei, Ying, Anne B. Hofseth, Elena Jelezcova, et al.. (2009). Differential effects of reactive nitrogen species on DNA base excision repair initiated by the alkyladenine DNA glycosylase. Carcinogenesis. 30(12). 2123–2129. 38 indexed citations

11.

Hussain, S. Perwez, Peijun He, Jeffrey Subleski, et al.. (2008). Nitric Oxide Is a Key Component in Inflammation-Accelerated Tumorigenesis. Cancer Research. 68(17). 7130–7136. 85 indexed citations

12.

Lei, Ying, Anne B. Hofseth, Darren D. Browning, et al.. (2007). Nitric Oxide Inactivates the Retinoblastoma Pathway in Chronic Inflammation. Cancer Research. 67(19). 9286–9293. 33 indexed citations

13.

Lei, Ying, S. Perwez Hussain, Khan Ma, et al.. (2005). Chronic Inflammation Promotes Retinoblastoma Protein Hyperphosphorylation and E2F1 Activation. Cancer Research. 65(20). 9132–9136. 45 indexed citations

14.

Staib, Frank, Ana I. Robles, Lyuba Varticovski, et al.. (2005). The p53 Tumor Suppressor Network Is a Key Responder to Microenvironmental Components of Chronic Inflammatory Stress. Cancer Research. 65(22). 10255–10264. 87 indexed citations

15.

Hofseth, Lorne J., Ana I. Robles, Michael Graham Espey, & Curtis C. Harris. (2005). Nitric Oxide Is a Signaling Molecule that Regulates Gene Expression. Methods in enzymology on CD-ROM/Methods in enzymology. 326–340. 14 indexed citations

16.

Hussain, S. Perwez, Glennwood E. Trivers, Lorne J. Hofseth, et al.. (2004). Nitric Oxide, a Mediator of Inflammation, Suppresses Tumorigenesis. Cancer Research. 64(19). 6849–6853. 108 indexed citations

17.

Robles, Ana I., Christin L. Hanigan, Lorne J. Hofseth, et al.. (2004). Apoptotic Signaling Pathways Induced by Nitric Oxide in Human Lymphoblastoid Cells Expressing Wild-Type or Mutant p53. Cancer Research. 64(9). 3022–3029. 58 indexed citations

18.

Hofseth, Lorne J., Mohammed Abdul Sattar Khan, Mark Ambrose, et al.. (2003). The adaptive imbalance in base excision–repair enzymes generates microsatellite instability in chronic inflammation. Journal of Clinical Investigation. 112(12). 1887–1894. 18 indexed citations

19.

Hofseth, Lorne J., Khan Ma, Mark Ambrose, et al.. (2003). The adaptive imbalance in base excision–repair enzymes generates microsatellite instability in chronic inflammation. Journal of Clinical Investigation. 112(12). 1887–1894. 170 indexed citations

20.

Zhou, Xiaoling, Michael Graham Espey, Lorne J. Hofseth, et al.. (2000). Inhibitory Effects of Nitric Oxide and Nitrosative Stress on Dopamine-β-Hydroxylase. Journal of Biological Chemistry. 275(28). 21241–21246. 27 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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