Lin Jiang

8.0k citations

52 papers · 5.6k indexed · 4 hit papers · h-index 30

Impact in

Physiology top 1%
- Alzheimer's disease research and treatments
Molecular Biology top 1%
- Protein Structure and Dynamics
- Enzyme Catalysis and Immobilization
- RNA and protein synthesis mechanisms
- Prion Diseases and Protein Misfolding
- Microbial Metabolic Engineering and Bioproduction

Papers in ⓘ

Molecular Biology 37
- Protein Structure and Dynamics 17
- Prion Diseases and Protein Misfolding 7
- Chemical Synthesis and Analysis 4
- Enzyme Catalysis and Immobilization 3
Physiology 19
- Alzheimer's disease research and treatments 19

Co-authors: David Baker (7 shared papers)David Eisenberg (22 shared papers)Eric A. Althoff (5 shared papers)Daniela Röthlisberger (3 shared papers)Alexandre Zanghellini (3 shared papers)Jamie L. Betker (2 shared papers)Jasmine L. Gallaher (2 shared papers)K. N. Houk (2 shared papers)
Journals: Journal of Biological Chemistry (6 papers)eLife (4 papers)Nature Communications (3 papers)Nature (2 papers)The FASEB Journal (2 papers)
Partner nations: United States China Switzerland

In The Last Decade

Lin Jiang

50 papers receiving 5.5k citations

Hit Papers

align trajectories log scale

Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel 2018 · 470 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2018 Nature Communications
2011 Nature
2008 Science
2008 Nature

Peers

Countries citing papers authored by Lin Jiang

Since Specialization

Citations

This map shows the geographic impact of Lin Jiang's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lin Jiang with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lin Jiang more than expected).

Fields of papers citing papers by Lin Jiang

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lin Jiang. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lin Jiang. The network helps show where Lin Jiang may publish in the future.

Co-authors

The 25 scholars most cited alongside Lin Jiang, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Lin Jiang Line = papers co-authored together Lin Jiang links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 52 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Kemp elimination catalysts by computational enzyme design Nature ·Daniela Röthlisberger, Olga Khersonsky, Andrew M. Wollacott, Lin Jiang, Jason DeChancie, Jamie L. Betker, Jasmine L. Gallaher, Eric A. Althoff, Alexandre Zanghellini, Orly Dym, Shira Albeck, K. N. Houk, Dan S. Tawfik, David Baker Hit paper breakdown →	2008	975
2	De Novo Computational Design of Retro-Aldol Enzymes Science ·Lin Jiang, Eric A. Althoff, Fernando R. Clemente, Lindsey Doyle, Daniela Röthlisberger, Alexandre Zanghellini, Jasmine L. Gallaher, Jamie L. Betker, Fujie Tanaka, Carlos F. Barbas, Donald Hilvert, K. N. Houk, Barry Stoddard, David Baker Hit paper breakdown →	2008	890
3	Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel Nature Communications ·Binsen Li, P. Ge, Kevin A. Murray, Phorum Sheth, Meng Zhang, Gayatri Nair, M.R. Sawaya, Woo Shik Shin, David R. Boyer, Shulin Ye, David Eisenberg, Z. Hong Zhou, Lin Jiang Hit paper breakdown →	2018	470
4	Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation Nature ·Stuart A. Sievers, John Karanicolas, Howard W. Chang, Anni Zhao, Lin Jiang, Onofrio Zirafi, Jason T. Stevens, Jan Münch, David Baker, David Eisenberg Hit paper breakdown →	2011	389
5	A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas Cancer Cell ·Alice Soragni, Deanna M. Janzen, Lisa M. Johnson, Anne Lindgren, Quynh Nguyen, E. Tiourin, A.B. Soriaga, Jing Lü, Lin Jiang, Kym F. Faull, Matteo Pellegrini, Sanaz Memarzadeh, David Eisenberg	2015	266
6	New algorithms and an in silico benchmark for computational enzyme design Protein Science ·Alexandre Zanghellini, Lin Jiang, Andrew M. Wollacott, Gong Cheng, Jens Meiler, Eric A. Althoff, Daniela Röthlisberger, David Baker	2006	259
7	Towards a Pharmacophore for Amyloid PLoS Biology ·Meytal Landau, M.R. Sawaya, Kym F. Faull, Arthur Laganowsky, Lin Jiang, Stuart A. Sievers, Jie Liu, Jorge R. Barrio, David Eisenberg	2011	168
8	Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly Nature Communications ·Xinrui Gui, Feng Luo, Yichen Li, Heng Zhou, Zhenheng Qin, Zhenying Liu, Jinge Gu, Muyun Xie, Kun Zhao, Bin Dai, Woo Shik Shin, Jianhua He, Lin He, Lin Jiang, Minglei Zhao, Bo Sun, Xueming Li, Cong Liu, Dan Li	2019	160
9	Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates Proceedings of the National Academy of Sciences ·Cong Liu, Minglei Zhao, Lin Jiang, Pin‐Nan Cheng, Ji-Yong Park, M.R. Sawaya, Anna Pensalfini, Dawei Gou, Arnold Berk, Charles Glabe, James S. Nowick, David Eisenberg	2012	160
10	The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure Proceedings of the National Academy of Sciences ·David R. Boyer, Binsen Li, Chuanqi Sun, Weijia Fan, Kang Zhou, Michael P. Hughes, M.R. Sawaya, Lin Jiang, David Eisenberg	2020	137
11	Robust design and optimization of retroaldol enzymes Protein Science ·Eric A. Althoff, Ling Wang, Lin Jiang, Lars Giger, Jonathan K. Lassila, Zhizhi Wang, Matthew D. Smith, Sanjay B. Hari, Peter Kast, Daniel Herschlag, Donald Hilvert, David Baker	2012	137
12	Structures of fibrils formed by α-synuclein hereditary disease mutant H50Q reveal new polymorphs Nature Structural & Molecular Biology ·David R. Boyer, Binsen Li, Chuanqi Sun, Weijia Fan, M.R. Sawaya, Lin Jiang, David Eisenberg	2019	136
13	Uncovering the Mechanism of Aggregation of Human Transthyretin Journal of Biological Chemistry ·Lorena Saelices, Lisa M. Johnson, Wilson Y. Liang, M.R. Sawaya, Duilio Cascio, Piotr Ruchała, Julian P. Whitelegge, Lin Jiang, Roland Riek, David Eisenberg	2015	119
14	A “solvated rotamer” approach to modeling water‐mediated hydrogen bonds at protein–protein interfaces Proteins Structure Function and Bioinformatics ·Lin Jiang, Brian Kuhlman, Tanja Kortemme, David Baker	2005	111
15	Structure-based discovery of fiber-binding compounds that reduce the cytotoxicity of amyloid beta eLife ·Lin Jiang, Cong Liu, D.J. Leibly, Meytal Landau, Minglei Zhao, Michael P. Hughes, David Eisenberg	2013	102
16	NELL-1 in the treatment of osteoporotic bone loss Nature Communications ·Aaron W. James, Jia Shen, Xinli Zhang, Greg Asatrian, Raghav Goyal, Jin Hee Kwak, Lin Jiang, Benjamin C. Bengs, Cymbeline T. Culiat, A. Simon Turner, Howard B. Seim, Benjamin M. Wu, Karen M. Lyons, John S. Adams, Kang Ting, Chia Soo	2015	96
17	Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity eLife ·Pascal Krotee, José A. Rodríguez, M.R. Sawaya, Duilio Cascio, F.E. Reyes, Dan Shi, Johan Hattne, Brent L. Nannenga, Marie E. Oskarsson, Stephan Philipp, Sarah L. Griner, Lin Jiang, Charles Glabe, Gunilla T. Westermark, Tamir Gonen, David Eisenberg	2017	89
18	Precise and Reversible Protein-Microtubule-Like Structure with Helicity Driven by Dual Supramolecular Interactions Journal of the American Chemical Society ·Guang Yang, Xiang Zhang, Zdravko Kochovski, Yufei Zhang, Bin Dai, Fuji Sakai, Lin Jiang, Yan Lü, Matthias Ballauff, Xueming Li, Cong Liu, Guosong Chen, Ming Jiang	2016	89
19	Amyloid β-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation Alzheimer s Research & Therapy ·Woo Shik Shin, Jing Di, Qin Cao, Binsen Li, Paul M. Seidler, Kevin A. Murray, Gal Bitan, Lin Jiang	2019	76
20	Protein Interactions Limit the Rate of Evolution of Photosynthetic Genes in Cyanobacteria Molecular Biology and Evolution ·Tuo Shi, Thomas S. Bibby, Lin Jiang, Andrew J. Irwin, Paul G. Falkowski	2005	67

About Lin Jiang

Lin Jiang is a scholar working on Molecular Biology, Physiology, Materials Chemistry, Pharmacology and Neurology, having authored 52 papers that have together received 5.6k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (19 papers), Protein Structure and Dynamics (17 papers), Prion Diseases and Protein Misfolding (7 papers), Enzyme Structure and Function (7 papers), Cholinesterase and Neurodegenerative Diseases (5 papers), Chemical Synthesis and Analysis (4 papers), Parkinson's Disease Mechanisms and Treatments (4 papers) and Enzyme Catalysis and Immobilization (3 papers). The work is most often cited by research in Physiology (1.5k citations), Molecular Biology (4.0k citations), Neurology (621 citations), Biomaterials (462 citations) and Neurology (223 citations). Lin Jiang has collaborated with scholars based in United States, China and Switzerland. Frequent co-authors include David Baker, David Eisenberg, Eric A. Althoff, Daniela Röthlisberger, Alexandre Zanghellini, Jamie L. Betker, Jasmine L. Gallaher, K. N. Houk, M.R. Sawaya and Andrew M. Wollacott. Their work appears in journals such as Journal of Biological Chemistry, eLife, Nature Communications, Nature and The FASEB Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact