Li-Mien Chen

790 citations

22 papers · 685 indexed · h-index 17

Impact in

Toxicology top 5%
- Bioactive Compounds and Antitumor Agents
Complementary and alternative medicine top 5%
- Nigella sativa pharmacological applications

Papers in ⓘ

Toxicology 2
Cancer Research 6

Co-authors: Chih‐Yang Huang (21 shared papers)Wei‐Wen Kuo (11 shared papers)Fuu‐Jen Tsai (11 shared papers)Chang‐Hai Tsai (9 shared papers)Yueh-Min Lin (8 shared papers)Hsi-Hsien Hsu (8 shared papers)Chung‐Jung Liu (7 shared papers)James A. Lin (7 shared papers)
Journals: Molecular and Cellular Biochemistry (5 papers)Food Chemistry (2 papers)The American Journal of Chinese Medicine (2 papers)Clinica Chimica Acta (2 papers)Endocrinology (1 paper)
Partner nations: Taiwan Vietnam Canada

In The Last Decade

Li-Mien Chen

22 papers receiving 683 citations

Peers

Countries citing papers authored by Li-Mien Chen

Since Specialization

Citations

This map shows the geographic impact of Li-Mien Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Li-Mien Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Li-Mien Chen more than expected).

Fields of papers citing papers by Li-Mien Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Li-Mien Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Li-Mien Chen. The network helps show where Li-Mien Chen may publish in the future.

Co-authors

The 25 scholars most cited alongside Li-Mien Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Li-Mien Chen Line = papers co-authored together Li-Mien Chen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 22 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	IGF-II/mannose-6-phosphate receptor signaling induced cell hypertrophy and atrial natriuretic peptide/BNP expression via Gαq interaction and protein kinase C-α/CaMKII activation in H9c2 cardiomyoblast cells Journal of Endocrinology ·Chun‐Hsien Chu, Bor‐Show Tzang, Li-Mien Chen, Chia‐Hua Kuo, Yi‐Chang Cheng, Lingyun Chen, Fuu‐Jen Tsai, Chang‐Hai Tsai, Wei‐Wen Kuo, Chih‐Yang Huang	2008	81
2	Thymoquinone Induces Caspase-Independent, Autophagic Cell Death in CPT-11-Resistant LoVo Colon Cancer via Mitochondrial Dysfunction and Activation of JNK and p38 Journal of Agricultural and Food Chemistry ·Ming-Cheng Chen, N. Lee, Hsi-Hsien Hsu, Tsung‐Jung Ho, Chuan‐Chou Tu, Dennis Jine-Yuan Hsieh, Yueh-Min Lin, Li-Mien Chen, Wei‐Wen Kuo, Chih‐Yang Huang	2015	69
3	Thymoquinone Induces Apoptosis in Oral Cancer Cells Through P38β Inhibition The American Journal of Chinese Medicine ·Ehab Abdelfadil, Ya-Hsin Cheng, Da‐Tian Bau, Wei-Jen Ting, Li-Mien Chen, Hsi-Hsien Hsu, Yueh-Min Lin, Ray‐Jade Chen, Fu-Jenn Tsai, Chang‐Hai Tsai, Chih‐Yang Huang	2013	55
4	Activation of Insulin-Like Growth Factor II Receptor Induces Mitochondrial-Dependent Apoptosis through Gαq and Downstream Calcineurin Signaling in Myocardial Cells Endocrinology ·Chun‐Hsien Chu, Bor‐Show Tzang, Li-Mien Chen, Chung‐Jung Liu, Fuu‐Jen Tsai, Chang‐Hai Tsai, James A. Lin, Wei‐Wen Kuo, Da‐Tian Bau, Chun‐Hsu Yao, Chih‐Yang Huang	2008	53
5	Effects of short- and long-term hypobaric hypoxia on Bcl2 family in rat heart International Journal of Cardiology ·Shin‐Da Lee, Wei‐Wen Kuo, Chieh‐Hsi Wu, Yueh-Min Lin, James A. Lin, Min‐Chi Lu, Ai-Lun Yang, Jer-Yuh Liu, Shyi-Gang P. Wang, Chung‐Jung Liu, Li-Mien Chen, Chih‐Yang Huang	2005	48
6	PP2A mediates diosmin p53 activation to block HA22T cell proliferation and tumor growth in xenografted nude mice through PI3K–Akt–MDM2 signaling suppression Food and Chemical Toxicology ·Tran Duc Dung, Cecilia Hsuan Day, Truong Viet Binh, Chih-Hsueh Lin, Hsi-Hsien Hsu, Cheng-Chuan Su, Yueh-Min Lin, Fuu‐Jen Tsai, Wei‐Wen Kuo, Li-Mien Chen, Chih‐Yang Huang	2012	43
7	Lipopolysaccharide upregulates uPA, MMP-2 and MMP-9 via ERK1/2 signaling in H9c2 cardiomyoblast cells Molecular and Cellular Biochemistry ·Yi‐Chang Cheng, Li-Mien Chen, Mu-Hsin Chang, Wei-Kung Chen, Fuu‐Jen Tsai, Chang‐Hai Tsai, Tung-Yuan Lai, Wei‐Wen Kuo, Chih‐Yang Huang, Chung‐Jung Liu	2009	39
8	Rhubarb inhibits hepatocellular carcinoma cell metastasis via GSK-3-β activation to enhance protein degradation and attenuate nuclear translocation of β-catenin Food Chemistry ·Kun-Hsi Tsai, Hau-Hsueh Hsien, Li-Mien Chen, Wei-Jen Ting, Yuh‐Shyong Yang, Chia‐Hua Kuo, Chang‐Hai Tsai, Fuu‐Jen Tsai, Henry J. Tsai, Chih‐Yang Huang	2012	32
9	Leu27IGF2 plays an opposite role to IGF1 to induce H9c2 cardiomyoblast cell apoptosis via Gαq signaling Journal of Molecular Endocrinology ·Ray‐Jade Chen, His-Chin Wu, Mu-Hsin Chang, Chao‐Hung Lai, Yun-Chen Tien, Jin-Ming Hwang, Wu‐Hsien Kuo, Fuu‐Jen Tsai, Chang‐Hai Tsai, Li-Mien Chen, Chih‐Yang Huang, Chun‐Hsien Chu	2009	31
10	JNK suppression is essential for 17β-Estradiol inhibits prostaglandin E2-Induced uPA and MMP-9 expressions and cell migration in human LoVo colon cancer cells Journal of Biomedical Science ·Hsi-Hsien Hsu, Wei‐Syun Hu, Yueh-Min Lin, Wei-Wen Kuo, Li-Mien Chen, Wei-Kung Chen, Jin-Ming Hwang, Fuu‐Jen Tsai, Chung‐Jung Liu, Chih‐Yang Huang	2011	28
11	17β-Estradiol reduces cardiac hypertrophy mediated through the up-regulation of PI3K/Akt and the suppression of calcineurin/NF-AT3 signaling pathways in rats Life Sciences ·Chieh‐Hsi Wu, Jer-Yuh Liu, Jia‐Ping Wu, Yi‐Hsien Hsieh, Chung‐Jung Liu, Jin-Ming Hwang, Shin‐Da Lee, Li-Mien Chen, Mu-Hsin Chang, Wei‐Wen Kuo, Jyh‐Cherng Shyu, Jen-Hsiang Tsai, Chih‐Yang Huang	2005	27
12	17β-Estradiol inhibits prostaglandin E2-induced COX-2 expressions and cell migration by suppressing Akt and ERK1/2 signaling pathways in human LoVo colon cancer cells Molecular and Cellular Biochemistry ·Tung-Yuan Lai, Li-Mien Chen, Jing-Ying Lin, Bor‐Show Tzang, James A. Lin, Chang-Hai Tsai, Yueh-Min Lin, Chih‐Yang Huang, Chung‐Jung Liu, Hsi-Hsien Hsu	2010	24
13	Serum insulin-like growth factor-axis and matrix metalloproteinases in patients with rheumatic arthritis or rheumatic heart disease Clinica Chimica Acta ·Shin‐Da Lee, Li-Mien Chen, Wei-Wen Kuo, Win-Tom Shu, Wu‐Hsien Kuo, Erh-Jung Huang, Chin-Chuan Tsai, Ping-Chun Li, Jer-Yuh Liu, Ter-Hsin Chen, Chih‐Yang Huang	2006	23
14	Endothelin-1 enhances cell migration through COX-2 up-regulation in human chondrosarcoma Biochimica et Biophysica Acta (BBA) - General Subjects ·Min Wu, Li-Mien Chen, His-Hsien Hsu, James A. Lin, Yueh-Min Lin, Fuu‐Jen Tsai, Chang‐Hai Tsai, Chih‐Yang Huang, Chih‐Hsin Tang	2013	22
15	Apoptotic and anti-proliferative effects of 17β-estradiol and 17β-estradiol-like compounds in the Hep3B cell line Molecular and Cellular Biochemistry ·Erh-Jung Huang, Cheng-Chung Wu, Hsien-Ping Huang, Jer-Yuh Liu, Chung-Sheng Lin, Yan‐Zin Chang, James A. Lin, Jaung‐Geng Lin, Li-Mien Chen, Shin‐Da Lee, Wei‐Wen Kuo, Chih‐Yang Huang	2006	17
16	Pro-inflammatory states and IGF-I level in ischemic heart disease with low or high serum iron Clinica Chimica Acta ·Shin‐Da Lee, Chih‐Yang Huang, Wen-Tong Shu, Ter-Hsin Chen, James A. Lin, Hsi-Hsien Hsu, Chung-Sheng Lin, Chung‐Jung Liu, Wei-Wen Kuo, Li-Mien Chen	2006	17
17	Over-expressed estrogen receptor-α up-regulates hTNF-α gene expression and down-regulates β-catenin signaling activity to induce the apoptosis and inhibit proliferation of LoVo colon cancer cells Molecular and Cellular Biochemistry ·Hsi-Hsien Hsu, Sue-Fei Cheng, Li-Mien Chen, Jer-Yu Liu, Chun‐Hsien Chu, Yi-Jiun Weng, Zih-Ying Li, Chung-Sheng Lin, Shin‐Da Lee, Wei‐Wen Kuo, Chih‐Yang Huang	2006	16
18	Short-term versus long-term intermittent hypobaric hypoxia on cardiac fibrosis and Fas death receptor dependent apoptotic pathway in rat hearts. PubMed ·Yueh-Min Lin, Shu-Kuei Huang, Hsueh Fang Wang, Li-Mien Chen, Fuu‐Jen Tsai, Hsi-Hsien Hsu, Chia‐Hua Kuo, Paulus S. Wang, Chih‐Yang Huang, Shin‐Da Lee	2008	16
19	The Proliferation and Migration Effects of Huangqi on RSC96 Schwann Cells The American Journal of Chinese Medicine ·Wen-Kuei Fang, Fu-Yang Ko, Hwai Lee Wang, Chia‐Hua Kuo, Li-Mien Chen, Fuu‐Jen Tsai, Chang‐Hai Tsai, Yueh-Sheng Chen, Wei-Wen Kuo, Chih‐Yang Huang	2009	15
20	Opposing Action of Estrogen Receptors α and β on Tumor Necrosis Factor-α Gene Expression and Caspase-8-mediated Apoptotic Effects in HA22T Cells Molecular and Cellular Biochemistry ·Erh-Jung Huang, Cheng-Chung Wu, Shin‐Da Lee, Juen-Hau Chen, Jer-Yuh Liu, Jiunn‐Liang Ko, James A. Lin, Min-Chi Lu, Li-Mien Chen, Chih‐Yang Huang, Wei‐Wen Kuo	2006	12

About Li-Mien Chen

Li-Mien Chen is a scholar working on Toxicology, Cancer Research, Genetics, Complementary and alternative medicine and Pharmacology, having authored 22 papers that have together received 685 indexed citations. Recurring topics across this work include Estrogen and related hormone effects (5 papers), Signaling Pathways in Disease (3 papers), Inflammatory mediators and NSAID effects (3 papers), Protein Kinase Regulation and GTPase Signaling (3 papers), Cardiac Fibrosis and Remodeling (3 papers), Nigella sativa pharmacological applications (2 papers), Genetic factors in colorectal cancer (2 papers) and Natural Compounds in Disease Treatment (2 papers). The work is most often cited by research in Toxicology (54 citations), Complementary and alternative medicine (101 citations), Cancer Research (117 citations), Pharmacology (55 citations) and Molecular Biology (328 citations). Li-Mien Chen has collaborated with scholars based in Taiwan, Vietnam and Canada. Frequent co-authors include Chih‐Yang Huang, Wei‐Wen Kuo, Fuu‐Jen Tsai, Chang‐Hai Tsai, Yueh-Min Lin, Hsi-Hsien Hsu, Chung‐Jung Liu, James A. Lin, Chun‐Hsien Chu and Shin‐Da Lee. Their work appears in journals such as Molecular and Cellular Biochemistry, Food Chemistry, The American Journal of Chinese Medicine, Clinica Chimica Acta and Endocrinology.

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