Lien Van Hoecke

2.7k total citations · 4 hit papers
50 papers, 2.0k citations indexed

About

Lien Van Hoecke is a scholar working on Molecular Biology, Immunology and Epidemiology. According to data from OpenAlex, Lien Van Hoecke has authored 50 papers receiving a total of 2.0k indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Molecular Biology, 20 papers in Immunology and 11 papers in Epidemiology. Recurrent topics in Lien Van Hoecke's work include Immunotherapy and Immune Responses (11 papers), Neuroinflammation and Neurodegeneration Mechanisms (10 papers) and RNA Interference and Gene Delivery (9 papers). Lien Van Hoecke is often cited by papers focused on Immunotherapy and Immune Responses (11 papers), Neuroinflammation and Neurodegeneration Mechanisms (10 papers) and RNA Interference and Gene Delivery (9 papers). Lien Van Hoecke collaborates with scholars based in Belgium, Germany and United States. Lien Van Hoecke's co-authors include Kenny Roose, Roosmarijn E. Vandenbroucke, Junhua Xie, Xavier Saelens, Freddy Haesebrouck, Stefaan De Koker, Emma R. Job, Johan Grooten, Sandra Van Lint and Qiqiong Li and has published in prestigious journals such as Journal of Biological Chemistry, Nature Communications and SHILAP Revista de lepidopterología.

In The Last Decade

Lien Van Hoecke

48 papers receiving 2.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Impact of Systemic Inflammation on Alzheimer’s Disease Pathology

2022 198 citations Junhua Xie, Lien Van Hoecke et al. Frontiers in Immunology profile →
The tremendous biomedical potential of bacterial extracellular vesicles

2022 144 citations Junhua Xie, Qiqiong Li et al. Trends in biotechnology profile →
Helicobacter pylori‐derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3‐C3aR signalling

2023 95 citations Junhua Xie, Griet Van Imschoot et al. Journal of Extracellular Vesicles profile →
Bacterial extracellular vesicles: an emerging avenue to tackle diseases

2023 86 citations Junhua Xie, Freddy Haesebrouck et al. Trends in Microbiology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Lien Van Hoecke Belgium	24	1.1k	575	227	219	214	50	2.0k
Susan J. Hagen United States	27	692 0.6×	530 0.9×	187 0.8×	215 1.0×	239 1.1×	61	2.1k
Changsheng Xing United States	22	1.2k 1.1×	653 1.1×	236 1.0×	202 0.9×	234 1.1×	38	2.3k
Albert Tai United States	32	1.7k 1.5×	691 1.2×	324 1.4×	374 1.7×	411 1.9×	74	3.4k
France Moreau Canada	26	1.3k 1.1×	373 0.6×	528 2.3×	312 1.4×	179 0.8×	59	2.3k
Guoku Hu United States	36	2.5k 2.2×	640 1.1×	214 0.9×	334 1.5×	175 0.8×	70	3.9k
Hang‐Rae Kim South Korea	30	820 0.7×	933 1.6×	243 1.1×	209 1.0×	155 0.7×	114	2.8k
Cristina Bonorino Brazil	25	855 0.8×	836 1.5×	227 1.0×	360 1.6×	147 0.7×	69	2.4k
Ting Jia China	11	785 0.7×	1.1k 2.0×	434 1.9×	348 1.6×	269 1.3×	29	2.5k
Chiara Medaglia Italy	19	633 0.6×	548 1.0×	336 1.5×	171 0.8×	98 0.5×	32	1.7k
Jianqiong Zhang China	22	970 0.9×	479 0.8×	147 0.6×	144 0.7×	145 0.7×	77	1.9k

Countries citing papers authored by Lien Van Hoecke

Since Specialization

Citations

This map shows the geographic impact of Lien Van Hoecke's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lien Van Hoecke with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lien Van Hoecke more than expected).

Fields of papers citing papers by Lien Van Hoecke

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lien Van Hoecke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lien Van Hoecke. The network helps show where Lien Van Hoecke may publish in the future.

Co-authorship network of co-authors of Lien Van Hoecke

This figure shows the co-authorship network connecting the top 25 collaborators of Lien Van Hoecke. A scholar is included among the top collaborators of Lien Van Hoecke based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lien Van Hoecke. Lien Van Hoecke is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Hoecke, Lien Van, et al.. (2025). Mesenchymal stromal cell extracellular vesicles as immune modulators and drug carriers in neurodegenerative disorders. Trends in Neurosciences. 48(11). 919–934. 2 indexed citations

Xie, Junhua, Lien Van Hoecke, Elien Van Wonterghem, et al.. (2025). The gut–brain axis in Alzheimer’s disease is shaped by commensal gut microbiota derived extracellular vesicles. Gut Microbes. 17(1). 2501193–2501193. 2 indexed citations

Geerts, Anja, et al.. (2024). Role of astrocytes and microglia in hepatic encephalopathy associated with advanced chronic liver disease: lessons from animal studies. Neural Regeneration Research. 20(12). 3461–3475. 3 indexed citations

Hochepied, Tino, Griet Van Imschoot, Elien Van Wonterghem, et al.. (2024). Challenging the conventional wisdom: Re‐evaluating Smpd3's role in extracellular vesicle biogenesis. SHILAP Revista de lepidopterología. 3(11). e70015–e70015. 1 indexed citations

Rojas, Juan J., Lien Van Hoecke, Miquel À. Conesa, et al.. (2024). A new MVA ancestor-derived oncolytic vaccinia virus induces immunogenic tumor cell death and robust antitumor immune responses. Molecular Therapy. 32(7). 2406–2422. 8 indexed citations

Hoecke, Lien Van, Griet Van Imschoot, Elien Van Wonterghem, et al.. (2023). Experimental hepatic encephalopathy causes early but sustained glial transcriptional changes. Journal of Neuroinflammation. 20(1). 130–130. 9 indexed citations

Xie, Junhua, Griet Van Imschoot, Elien Van Wonterghem, et al.. (2023). Helicobacter pylori‐derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3‐C3aR signalling. Journal of Extracellular Vesicles. 12(2). e12306–e12306. 95 indexed citations breakdown →

Hoecke, Lien Van, Junhua Xie, Griet Van Imschoot, et al.. (2023). An immunological puzzle: The adaptive immune system fuels Alzheimer’s disease pathology. Brain Behavior and Immunity. 117. 122–134. 4 indexed citations

Xie, Junhua, Freddy Haesebrouck, Lien Van Hoecke, & Roosmarijn E. Vandenbroucke. (2023). Bacterial extracellular vesicles: an emerging avenue to tackle diseases. Trends in Microbiology. 31(12). 1206–1224. 86 indexed citations breakdown →

10.

Xie, Junhua, Sriram Balusu, Elien Van Wonterghem, et al.. (2022). Choroid plexus-derived extracellular vesicles exhibit brain targeting characteristics. Biomaterials. 290. 121830–121830. 13 indexed citations

11.

Vandenbroucke, Roosmarijn E., et al.. (2022). Recent insights into viral infections as a trigger and accelerator in alzheimer's disease. Drug Discovery Today. 27(11). 103340–103340. 12 indexed citations

12.

Xie, Junhua, Qiqiong Li, Freddy Haesebrouck, Lien Van Hoecke, & Roosmarijn E. Vandenbroucke. (2022). The tremendous biomedical potential of bacterial extracellular vesicles. Trends in biotechnology. 40(10). 1173–1194. 144 indexed citations breakdown →

13.

Xie, Junhua, Lien Van Hoecke, & Roosmarijn E. Vandenbroucke. (2022). The Impact of Systemic Inflammation on Alzheimer’s Disease Pathology. Frontiers in Immunology. 12. 796867–796867. 198 indexed citations breakdown →

14.

Hoecke, Lien Van, Sander Lefere, Anja Geerts, et al.. (2021). The neurogliovascular unit in hepatic encephalopathy. JHEP Reports. 3(5). 100352–100352. 37 indexed citations

15.

Hoecke, Lien Van, Caroline Van Cauwenberghe, Verena Börger, et al.. (2021). Anti-Inflammatory Mesenchymal Stromal Cell-Derived Extracellular Vesicles Improve Pathology in Niemann–Pick Type C Disease. Biomedicines. 9(12). 1864–1864. 21 indexed citations

16.

Xie, Junhua, Nina Gorlé, Charysse Vandendriessche, et al.. (2021). Low-grade peripheral inflammation affects brain pathology in the AppNL-G-Fmouse model of Alzheimer’s disease. Acta Neuropathologica Communications. 9(1). 163–163. 44 indexed citations

17.

Hoecke, Silvie Van den, Marlies Ballegeer, Bram Vrancken, et al.. (2021). In Vivo Therapy with M2e-Specific IgG Selects for an Influenza A Virus Mutant with Delayed Matrix Protein 2 Expression. mBio. 12(4). e0074521–e0074521. 6 indexed citations

18.

Spitaels, Jan, Lien Van Hoecke, Kenny Roose, Georg Kochs, & Xavier Saelens. (2019). Mx1 in Hematopoietic Cells Protects against Thogoto Virus Infection. Journal of Virology. 93(15). 24 indexed citations

19.

Hoecke, Lien Van, Emma R. Job, Xavier Saelens, & Kenny Roose. (2017). Bronchoalveolar Lavage of Murine Lungs to Analyze Inflammatory Cell Infiltration. Journal of Visualized Experiments. 50 indexed citations

20.

Lambricht, Laure, Kévin Vanvarenberg, Ans De Beuckelaer, et al.. (2016). Coadministration of a Plasmid Encoding HIV-1 Gag Enhances the Efficacy of Cancer DNA Vaccines. Molecular Therapy. 24(9). 1686–1696. 19 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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