Le Chang

7.1k total citations · 3 hit papers
32 papers, 4.8k citations indexed

About

Le Chang is a scholar working on Molecular Biology, Cancer Research and Surgery. According to data from OpenAlex, Le Chang has authored 32 papers receiving a total of 4.8k indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Molecular Biology, 10 papers in Cancer Research and 4 papers in Surgery. Recurrent topics in Le Chang's work include Metabolomics and Mass Spectrometry Studies (7 papers), MicroRNA in disease regulation (7 papers) and Cancer-related molecular mechanisms research (5 papers). Le Chang is often cited by papers focused on Metabolomics and Mass Spectrometry Studies (7 papers), MicroRNA in disease regulation (7 papers) and Cancer-related molecular mechanisms research (5 papers). Le Chang collaborates with scholars based in China, Canada and United States. Le Chang's co-authors include Jianguo Xia, Guangyan Zhou, Zhiqiang Pang, Jasmine Chong, M. Barrette, David Anderson de Lima Morais, Pierre‐Étienne Jacques, Shuzhao Li, Othman Soufan and Jessica Ewald and has published in prestigious journals such as Nucleic Acids Research, Nature Genetics and Brain.

In The Last Decade

Le Chang

27 papers receiving 4.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights

2021 2.8k citations Zhiqiang Pang, Jasmine Chong et al. Nucleic Acids Research profile →
Using MetaboAnalyst 5.0 for LC–HRMS spectra processing, multi-omics integration and covariate adjustment of global metabolomics data

2022 884 citations Zhiqiang Pang, Guangyan Zhou et al. Nature Protocols profile →
miRNet 2.0: network-based visual analytics for miRNA functional analysis and systems biology

2020 569 citations Le Chang, Guangyan Zhou et al. Nucleic Acids Research profile →

Peers

Countries citing papers authored by Le Chang

Since Specialization

Citations

This map shows the geographic impact of Le Chang's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Le Chang with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Le Chang more than expected).

Fields of papers citing papers by Le Chang

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Le Chang. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Le Chang. The network helps show where Le Chang may publish in the future.

Co-authorship network of co-authors of Le Chang

This figure shows the co-authorship network connecting the top 25 collaborators of Le Chang. A scholar is included among the top collaborators of Le Chang based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Le Chang. Le Chang is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Exploring and visualizing stratified GWAS results with PheWeb2 2026 ·Nature Genetics ·(unknown), (unknown), Le Chang, (unknown), S. N. Wickramasinghe, Alexandra Mayhew, (unknown), (unknown), (unknown), (unknown)	0
2	The relationship between kidney health and neurodegenerative diseases 2025 ·Brain ·(unknown), Le Chang, (unknown), (unknown), (unknown), (unknown), Sarah A. Gagliano Taliun	0
3	STAT3 inhibition mitigates experimental autoimmune gastritis by restoring Th17/Treg immune balance 2025 ·Immunologic Research ·(unknown), (unknown), (unknown), Wenjuan Liu, Xiaoxue Gao, Le Chang, Ping Cao	1
4	Optimizing HIV testing: Comparing diagnostic signatures and assay performance in ART-treated and general screening populations 2025 ·Clinica Chimica Acta ·Qian Liu, Xinru Liu, Le Chang, Huimin Ji, Huizhen Sun, Ying Yan, Junjie Xu, Lunan Wang	1
5	Ribosomal proteins in hepatocellular carcinoma: mysterious but promising 2024 ·Cell & Bioscience ·(unknown), Huizhen Sun, Ling Mei, Ying Yan, Huimin Ji, Le Chang, Lunan Wang	2
6	A data-centric perspective on exposomics data analysis 2024 ·Le Chang, Jessica Ewald, (unknown), Stéphane Bayen, Jianguo Xia	3
7	A convolutional neural network–based system for identifying neuroendocrine neoplasms and multiple types of lesions in the pancreas using EUS (with videos) 2024 ·Gastrointestinal Endoscopy ·Jianjiao Ni, (unknown), (unknown), Yong Jin Song, Guoming Zhang, (unknown), Limei Wang, Peng Wang, Guangchao Li, Shiyang Ma, Jun Gao, Le Chang, Xinxin Zhang, Ning Zhong, Zhen Li	2
8	mGWAS-Explorer 2.0: Causal Analysis and Interpretation of Metabolite–Phenotype Associations 2023 ·Metabolites ·Le Chang, Guangyan Zhou, Jianguo Xia	14
9	Using MetaboAnalyst 5.0 for LC–HRMS spectra processing, multi-omics integration and covariate adjustment of global metabolomics data breakdown → 2022 ·Nature Protocols ·Zhiqiang Pang, Guangyan Zhou, Jessica Ewald, Le Chang, Orçun Haçarız, Niladri Basu, Jianguo Xia	884
10	The lncRNA TERC promotes gastric cancer cell proliferation, migration, and invasion by sponging miR-423-5p to regulate SOX12 expression 2022 ·Annals of Translational Medicine ·(unknown), Min Wu, Le Chang, (unknown), Xiaoli Yang, Dongliang Li, Jiaojiao Wang, Jie Qu, Qiang Hou, Xiaoyan Huang, Cuixiang Xu	5
11	MicroRNA Regulatory Network Analysis Using miRNet 2.0 2022 ·Methods in molecular biology ·Le Chang, Jianguo Xia	64
12	Notch signaling inhibition protects against root resorption in experimental immature tooth movement in rats 2021 ·American Journal of Orthodontics and Dentofacial Orthopedics ·Xinyi Li, Jingchen Xu, Yuanyuan Yin, Ting Liu, Le Chang, Shushu He, (unknown)	7
13	MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights breakdown → 2021 ·Nucleic Acids Research ·Zhiqiang Pang, Jasmine Chong, Guangyan Zhou, David Anderson de Lima Morais, Le Chang, M. Barrette, (unknown), Pierre‐Étienne Jacques, Shuzhao Li, Jianguo Xia	2801
14	Human Periodontal Ligament Stem Cell-Derived Exosomes Promote Bone Regeneration by Altering MicroRNA Profiles 2020 ·Stem Cells International ·Ting Liu, (unknown), Xue Zou, Jingchen Xu, Shushu He, Le Chang, Xinyi Li, Yuanyuan Yin, Mi Tian, Ziyu Li, Jialiang Zhou, Xiaoge Jiang, Song Chen	58
15	Structural Dynamics of Tri-Nuleosome by Coarse-Grained Simulations: Effects of Histone Tail Acetylation 2016 ·Biophysical Journal ·Le Chang, Shoji Takada	1
16	Histone acetylation dependent energy landscapes in tri-nucleosome revealed by residue-resolved molecular simulations 2016 ·Scientific Reports ·Le Chang, Shoji Takada	34
17	Review of microRNA in osteosarcoma and chondrosarcoma 2015 ·Medical Oncology ·Le Chang, (unknown), (unknown), Michelle Scott, Aaron W. James	48
18	PA28gamma emerges as a novel functional target of tumour suppressor microRNA-7 in non-small-cell lung cancer 2013 ·British Journal of Cancer ·Shijiang Xiong, (unknown), Pei Jiang, Liu R, (unknown), Jin Qian, Jie Gu, Le Chang, (unknown), Yingjie Chu	56
19	Protein‐specific force field derived from the fragment molecular orbital method can improve protein–ligand binding interactions 2013 ·Journal of Computational Chemistry ·Le Chang, Takeshi Ishikawa, Kazuo Kuwata, Shoji Takada	14
20	Additive Effects of Sonic Hedgehog and Nell-1 Signaling in Osteogenic Versus Adipogenic Differentiation of Human Adipose-Derived Stromal Cells 2012 ·Stem Cells and Development ·Aaron W. James, Shen Pang, Asal Askarinam, Mirko Corselli, Janette N. Zara, Raghav Goyal, Le Chang, (unknown), Jia Shen, Wei Yuan, David Murray‐Stoker, Xinli Zhang, John S. Adams, Ting Kang, Chia Soo	76

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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