Kim Bottomly

19.2k total citations · 5 hit papers
153 papers, 16.2k citations indexed

About

Kim Bottomly is a scholar working on Immunology, Radiology, Nuclear Medicine and Imaging and Physiology. According to data from OpenAlex, Kim Bottomly has authored 153 papers receiving a total of 16.2k indexed citations (citations by other indexed papers that have themselves been cited), including 122 papers in Immunology, 25 papers in Radiology, Nuclear Medicine and Imaging and 22 papers in Physiology. Recurrent topics in Kim Bottomly's work include T-cell and B-cell Immunology (84 papers), Immune Cell Function and Interaction (81 papers) and Immunotherapy and Immune Responses (44 papers). Kim Bottomly is often cited by papers focused on T-cell and B-cell Immunology (84 papers), Immune Cell Function and Interaction (81 papers) and Immunotherapy and Immune Responses (44 papers). Kim Bottomly collaborates with scholars based in United States, France and Belgium. Kim Bottomly's co-authors include Stephanie L. Constant, Charles A. Janeway, Christina A. Herrick, Lauren Cohn, Simon R. Carding, Damani A. Piggott, David Leitenberg, Stephanie C. Eisenbarth, Theresa Pasqualini and James W. Huleatt and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Kim Bottomly

153 papers receiving 15.8k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

INDUCTION OF TH1 AND TH2 CD4⁺T CELL RESPONSES:The Alternative Approaches

1997 1.3k citations Stephanie L. Constant, Kim Bottomly profile →
Lipopolysaccharide-enhanced, Toll-like Receptor 4–dependent T Helper Cell Type 2 Responses to Inhaled Antigen

2002 949 citations Stephanie C. Eisenbarth, Damani A. Piggott et al. The Journal of Experimental Medicine profile →
Signals and signs for lymphocyte responses

1994 711 citations Charles A. Janeway, Kim Bottomly profile →
Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells.

1995 579 citations Stephanie L. Constant, Theresa Pasqualini et al. The Journal of Experimental Medicine profile →
Transcription Factor GATA-3 Is Differentially Expressed in Murine Th1 and Th2 Cells and Controls Th2-specific Expression of the Interleukin-5 Gene

1997 552 citations Lauren Cohn, Kim Bottomly et al. profile →

Peers

Countries citing papers authored by Kim Bottomly

Since Specialization

Citations

This map shows the geographic impact of Kim Bottomly's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kim Bottomly with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kim Bottomly more than expected).

Fields of papers citing papers by Kim Bottomly

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kim Bottomly. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kim Bottomly. The network helps show where Kim Bottomly may publish in the future.

Co-authorship network of co-authors of Kim Bottomly

This figure shows the co-authorship network connecting the top 25 collaborators of Kim Bottomly. A scholar is included among the top collaborators of Kim Bottomly based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kim Bottomly. Kim Bottomly is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Scaleable production of highly loaded protein nanoparticles for immune modulation 2024 ·Communications Materials ·Michael J. Caplan, Richard Baldwin, Xiangyun Yin, Alexander Grishin, Stephanie C. Eisenbarth, Hugh A. Sampson, Kim Bottomly, Robert K. Prud’homme	4
2	CTLA-4 Differentially Regulates the Immunological Synapse in CD4 T Cell Subsets 2007 ·The Journal of Immunology ·Rachael P. Jackman, Fran Balamuth, Kim Bottomly	15
3	CD4 Raft Association and Signaling Regulate Molecular Clustering at the Immunological Synapse Site 2004 ·The Journal of Immunology ·Fran Balamuth, Jennifer L. Brogdon, Kim Bottomly	59
4	Regulated Recruitment of MHC Class II and Costimulatory Molecules to Lipid Rafts in Dendritic Cells 2004 ·The Journal of Immunology ·(unknown), Juli Unternaehrer, Ira Mellman, Kim Bottomly	39
5	IL-13 Is Necessary, Not Simply Sufficient, for Epicutaneously Induced Th2 Responses to Soluble Protein Antigen 2003 ·The Journal of Immunology ·Christina A. Herrick, Lan Xu, Andrew N. J. McKenzie, Robert E. Tigelaar, Kim Bottomly	80
6	Engineered Recombinant Peanut Protein and Heat-Killed Listeria monocytogenes Coadministration Protects Against Peanut-Induced Anaphylaxis in a Murine Model 2003 ·The Journal of Immunology ·Xiu-Min Li, Kamal Srivastava, James W. Huleatt, Kim Bottomly, A. Wesley Burks, Hugh A. Sampson	115
7	A Pool of Central Memory-Like CD4 T Cells Contains Effector Memory Precursors 2003 ·The Journal of Immunology ·J. Magarian Blander, Derek B. Sant’Angelo, Daniela Metz, Sangwon V. Kim, Richard A. Flavell, Kim Bottomly, Charles A. Janeway	26
8	Role of TCR-Induced Extracellular Signal-Regulated Kinase Activation in the Regulation of Early IL-4 Expression in Naive CD4+ T Cells 2003 ·The Journal of Immunology ·(unknown), Jennifer L. Brogdon, Kim Bottomly	123
9	Resident lung antigen-presenting cells have the capacity to promote Th2 T cell differentiation in situ 2002 ·Journal of Clinical Investigation ·Stephanie L. Constant, Jennifer L. Brogdon, Damani A. Piggott, Christina A. Herrick, Irene Visintin, Nancy H. Ruddle, Kim Bottomly	10
10	The Potency of TCR Signaling Differentially Regulates NFATc/p Activity and Early IL-4 Transcription in Naive CD4+ T Cells 2002 ·The Journal of Immunology ·Jennifer L. Brogdon, David Leitenberg, Kim Bottomly	112
11	IL-4 Promotes Airway Eosinophilia by Suppressing IFN-γ Production: Defining a Novel Role for IFN-γ in the Regulation of Allergic Airway Inflammation 2001 ·The Journal of Immunology ·Lauren Cohn, Christina A. Herrick, Naiqian Niu, Robert Homer, Kim Bottomly	76
12	Identification of Human Lung and Skin Proteins Conjugated with Hexamethylene Diisocyanate in Vitro and in Vivo 2000 ·American Journal of Respiratory and Critical Care Medicine ·Adam V. Wisnewski, Ranjana Srivastava, (unknown), Lan Xu, Ranulfo Lemus, Hilary Cain, Nadine M Magoski, Meryl H. Karol, Kim Bottomly, (unknown)	99
13	Th2-induced airway mucus production is dependent on IL-4Ralpha, but not on eosinophils. 1999 ·PubMed ·Lauren Cohn, Robert Homer, Heather MacLeod, Markus Mohrs, Frank Brombacher, Kim Bottomly	207
14	The extracellular domain of CD45 controls association with the CD4-T cell receptor complex and the response to antigen-specific stimulation. 1996 ·The Journal of Experimental Medicine ·David Leitenberg, Thomas J. Novak, Donna L. Färber, Brian R. Smith, Kim Bottomly	101
15	Involvement of gamma delta T cells in respiratory virus infections. 1991 ·PubMed ·Peter C. Doherty, W Allan, Maryna C. Eichelberger, S. Hou, Kim Bottomly, Simon R. Carding	8
16	Cytokines in T-cell development 1991 ·Immunology Today ·Simon R. Carding, Adrian Hayday, Kim Bottomly	144
17	Autocrine growth of CD4+ T cells. Differential effects of IL-1 on helper and inflammatory T cells. 1988 ·The Journal of Immunology ·Laurence Greenbaum, Jay B. Horowitz, Amber N. Woods, Theresa Pasqualini, Edward Reich, Kim Bottomly	160
18	IL-4 (B cell stimulatory factor 1) exhibits thymocyte growth factor activity in the presence of IL-2. 1988 ·The Journal of Immunology ·Simon R. Carding, Kim Bottomly	16
19	T cell-dependent hapten-specific and polyclonal B cell responses require release of interleukin 5. 1988 ·The Journal of Immunology ·R. A. Rasmussen, Kiyoshi Takatsu, Norihiro Harada, (unknown), Kim Bottomly	41
20	Antigen-specific helper T cells required for dominant idiotype expression are not H-2 restricted 1981 ·The Journal of Experimental Medicine ·Kim Bottomly, (unknown)	37

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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