Keith Mikule

2.3k total citations · 1 hit paper
29 papers, 1.7k citations indexed

About

Keith Mikule is a scholar working on Oncology, Molecular Biology and Cell Biology. According to data from OpenAlex, Keith Mikule has authored 29 papers receiving a total of 1.7k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Oncology, 15 papers in Molecular Biology and 5 papers in Cell Biology. Recurrent topics in Keith Mikule's work include PARP inhibition in cancer therapy (13 papers), Microtubule and mitosis dynamics (5 papers) and DNA Repair Mechanisms (3 papers). Keith Mikule is often cited by papers focused on PARP inhibition in cancer therapy (13 papers), Microtubule and mitosis dynamics (5 papers) and DNA Repair Mechanisms (3 papers). Keith Mikule collaborates with scholars based in United States, South Korea and Switzerland. Keith Mikule's co-authors include Stephen Doxsey, Wendy Zimmerman, Philipp Kaldis, Polla Hergert, Bénédicte Delaval, Chiang J. Li, Wěi Li, Youzhi Li, Yuan Gao and David Leggett and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Neuroscience.

In The Last Decade

Keith Mikule

27 papers receiving 1.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Suppression of cancer relapse and metastasis by inhibiting cancer stemness

2015 382 citations Youzhi Li, Harry A. Rogoff et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Keith Mikule United States	15	999	782	518	197	187	29	1.7k
David Karnak United States	19	1.2k 1.2×	565 0.7×	384 0.7×	173 0.9×	86 0.5×	29	1.6k
Scott T. Eblen United States	24	1.8k 1.8×	445 0.6×	552 1.1×	218 1.1×	117 0.6×	41	2.3k
Jiaxue Wu China	28	2.0k 2.0×	675 0.9×	249 0.5×	350 1.8×	387 2.1×	53	2.6k
Barbara Nicke Germany	14	1.1k 1.1×	397 0.5×	293 0.6×	212 1.1×	92 0.5×	24	1.5k
Richard E. Cutler United States	19	1.1k 1.2×	506 0.6×	234 0.5×	165 0.8×	94 0.5×	46	1.6k
Verline Justilien United States	21	1.3k 1.3×	475 0.6×	261 0.5×	328 1.7×	118 0.6×	31	1.7k
Anthony Polverino United States	18	2.3k 2.3×	697 0.9×	463 0.9×	240 1.2×	113 0.6×	29	2.8k
Cinzia Rinaldo Italy	23	1.4k 1.4×	832 1.1×	247 0.5×	312 1.6×	152 0.8×	40	1.8k
Lucia Cicchillitti Italy	23	1.0k 1.0×	370 0.5×	293 0.6×	463 2.4×	100 0.5×	31	1.5k
Angelique W. Whitehurst United States	23	1.4k 1.4×	343 0.4×	296 0.6×	238 1.2×	140 0.7×	36	1.8k

Countries citing papers authored by Keith Mikule

Since Specialization

Citations

This map shows the geographic impact of Keith Mikule's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Keith Mikule with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Keith Mikule more than expected).

Fields of papers citing papers by Keith Mikule

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Keith Mikule. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Keith Mikule. The network helps show where Keith Mikule may publish in the future.

Co-authorship network of co-authors of Keith Mikule

This figure shows the co-authorship network connecting the top 25 collaborators of Keith Mikule. A scholar is included among the top collaborators of Keith Mikule based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Keith Mikule. Keith Mikule is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Wang, Zebin, Kaiming Sun, Yonghong Xiao, et al.. (2019). Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models. Scientific Reports. 9(1). 1853–1853. 178 indexed citations

Sambade, Maria J., Amanda E.D. Van Swearingen, Marni B. McClure, et al.. (2019). Efficacy and pharmacodynamics of niraparib in BRCA-mutant and wild-type intracranial triple-negative breast cancer murine models. Neuro-Oncology Advances. 1(1). vdz005–vdz005. 12 indexed citations

Póti, Ádám, Yonghong Xiao, Orsolya Pipek, et al.. (2018). Long-term treatment with the PARP inhibitor niraparib does not increase the mutation load in cell line models and tumour xenografts. British Journal of Cancer. 119(11). 1392–1400. 22 indexed citations

Sun, Kaiming, Yonghong Xiao, Bin Feng, et al.. (2018). Abstract 1724: Evaluation of niraparib in combination with anti-PD1/anti-PD-L1 in preclinical models. Cancer Research. 78(13_Supplement). 1724–1724. 6 indexed citations

Carey, Jason P.W., Cansu Karakaş, Tuyen Bui, et al.. (2017). Synthetic Lethality of PARP Inhibitors in Combination with MYC Blockade Is Independent of BRCA Status in Triple-Negative Breast Cancer. Cancer Research. 78(3). 742–757. 103 indexed citations

Gu, Chungang, Michelle L. Lamb, Jeffrey W. Johannes, et al.. (2016). Modulating the strength of hydrogen bond acceptors to achieve low Caco2 efflux for oral bioavailability of PARP inhibitors blocking centrosome clustering. Bioorganic & Medicinal Chemistry Letters. 26(19). 4775–4780. 5 indexed citations

Déas, Olivier, Stefano Cairo, Keith Wilcoxen, et al.. (2016). Abstract 4353: Preclinical evaluation of the PARP inhibitor niraparib and cytotoxic chemotherapy alone or in combination in a panel of 25 triple-negative breast cancer PDX models: Relevance of BRCA mutations, HRD status and other biomarkers. Cancer Research. 76(14_Supplement). 4353–4353. 2 indexed citations

Potter, Jennifer, et al.. (2016). Evaluation of clinical-stage PARP inhibitors in cell-based assays to correlate PARP suppression with functional impact on DNA repair. European Journal of Cancer. 69. S123–S124. 8 indexed citations

Li, Youzhi, Harry A. Rogoff, Sarah Keates, et al.. (2015). Suppression of cancer relapse and metastasis by inhibiting cancer stemness. Proceedings of the National Academy of Sciences. 112(6). 1839–1844. 382 indexed citations breakdown →

10.

Yang, Bin, Michelle L. Lamb, Tao Zhang, et al.. (2014). Discovery of Potent KIFC1 Inhibitors Using a Method of Integrated High-Throughput Synthesis and Screening. Journal of Medicinal Chemistry. 57(23). 9958–9970. 35 indexed citations

11.

Mayo, Michele, Shaun Grosskurth, Xin Wang, et al.. (2013). Abstract A221: Novel PARP6 inhibitors demonstrate in vivo efficacy in xenograft models.. Molecular Cancer Therapeutics. 12(11_Supplement). A221–A221.

12.

Blažková, Hana, Conrad von Schubert, Keith Mikule, et al.. (2007). The IKK Inhibitor BMS-345541 Affects Multiple Mitotic Cell Cycle Transitions. Cell Cycle. 6(20). 2531–2540. 9 indexed citations

13.

Mikule, Keith, et al.. (2006). Loss of centrosome integrity induces p38—p53—p21-dependent G1—S arrest. Nature Cell Biology. 9(2). 160–170. 244 indexed citations

14.

Sun, Xiangao, Youzhi Li, Wěi Li, et al.. (2006). Selective Induction of Necrotic Cell Death in Cancer Cells by β-Lapachone through Activation of DNA Damage Response Pathway. Cell Cycle. 5(17). 2029–2035. 26 indexed citations

15.

Doxsey, Stephen, Wendy Zimmerman, & Keith Mikule. (2005). Centrosome control of the cell cycle. Trends in Cell Biology. 15(6). 303–311. 259 indexed citations

16.

Mikule, Keith, Somkiat Sunpaweravong, Jesse C. Gatlin, & Karl H. Pfenninger. (2003). Eicosanoid Activation of Protein Kinase C ϵ. Journal of Biological Chemistry. 278(23). 21168–21177. 28 indexed citations

17.

Mikule, Keith, Jesse C. Gatlin, Becky A. de la Houssaye, & Karl H. Pfenninger. (2002). Growth Cone Collapse Induced by Semaphorin 3A Requires 12/15-Lipoxygenase. Journal of Neuroscience. 22(12). 4932–4941. 57 indexed citations

18.

Houssaye, Becky A. de la, et al.. (2000). Thrombin causes pseudopod detachment via a pathway involving cytosolic phospholipase A2 and 12/15-lipoxygenase products.. PubMed. 11(1). 19–30. 8 indexed citations

19.

Helmke, Steve M., et al.. (1998). SRC binding to the cytoskeleton, triggered by growth cone attachment to laminin, is protein tyrosine phosphatase-dependent. Journal of Cell Science. 111(16). 2465–2475. 24 indexed citations

20.

Erdman, Susan E., Phyllis J. Kanki, Frances M. Moore, et al.. (1996). Clusters of Lymphoma in Ferrets. Cancer Investigation. 14(3). 225–230. 23 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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