Kazuhiro Irie

7.3k total citations
250 papers, 5.5k citations indexed

About

Kazuhiro Irie is a scholar working on Molecular Biology, Pharmacology and Physiology. According to data from OpenAlex, Kazuhiro Irie has authored 250 papers receiving a total of 5.5k indexed citations (citations by other indexed papers that have themselves been cited), including 140 papers in Molecular Biology, 77 papers in Pharmacology and 72 papers in Physiology. Recurrent topics in Kazuhiro Irie's work include Alzheimer's disease research and treatments (69 papers), Microbial Natural Products and Biosynthesis (38 papers) and Protein Kinase Regulation and GTPase Signaling (34 papers). Kazuhiro Irie is often cited by papers focused on Alzheimer's disease research and treatments (69 papers), Microbial Natural Products and Biosynthesis (38 papers) and Protein Kinase Regulation and GTPase Signaling (34 papers). Kazuhiro Irie collaborates with scholars based in Japan, United States and Tunisia. Kazuhiro Irie's co-authors include Kazuma Murakami, Hajime Ohigashi, Takahiko Shimizu, Takuji Shirasawa, Yu Nakagawa, Yuichi Masuda, Masaya Nagao, Ryo C. Yanagita, Mayumi Shindo and Akira Morimoto and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Kazuhiro Irie

242 papers receiving 5.5k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Kazuhiro Irie Japan	39	2.9k	2.1k	1.4k	716	568	250	5.5k
Rona R. Ramsay United States	46	3.6k 1.3×	1.0k 0.5×	1.2k 0.8×	1.3k 1.8×	615 1.1×	151	7.7k
David G. Tew United Kingdom	30	1.8k 0.6×	1.2k 0.6×	523 0.4×	406 0.6×	381 0.7×	57	4.2k
Claudia Binda Italy	45	4.1k 1.4×	424 0.2×	1.4k 1.0×	1.8k 2.5×	622 1.1×	81	7.1k
David W. Cushman Malaysia	30	6.0k 2.1×	839 0.4×	578 0.4×	611 0.9×	552 1.0×	45	8.4k
Arthur A. Patchett United States	39	3.5k 1.2×	679 0.3×	874 0.6×	1.4k 2.0×	393 0.7×	126	6.7k
Thomas D. Hurley United States	48	3.9k 1.4×	795 0.4×	343 0.2×	413 0.6×	226 0.4×	114	7.2k
Koji Yamada Japan	44	3.3k 1.2×	644 0.3×	834 0.6×	2.1k 2.9×	101 0.2×	369	8.8k
Andreas Koeberle Germany	41	1.8k 0.6×	359 0.2×	1.6k 1.1×	832 1.2×	273 0.5×	134	4.5k
Dennis R. Petersen United States	53	4.4k 1.6×	1.4k 0.7×	466 0.3×	667 0.9×	116 0.2×	177	9.2k
Chris Beecher United States	30	3.4k 1.2×	569 0.3×	482 0.3×	510 0.7×	110 0.2×	66	6.4k

Countries citing papers authored by Kazuhiro Irie

Since Specialization

Citations

This map shows the geographic impact of Kazuhiro Irie's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kazuhiro Irie with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kazuhiro Irie more than expected).

Fields of papers citing papers by Kazuhiro Irie

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kazuhiro Irie. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kazuhiro Irie. The network helps show where Kazuhiro Irie may publish in the future.

Co-authorship network of co-authors of Kazuhiro Irie

This figure shows the co-authorship network connecting the top 25 collaborators of Kazuhiro Irie. A scholar is included among the top collaborators of Kazuhiro Irie based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kazuhiro Irie. Kazuhiro Irie is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Nakagawa, Yu, Y. Manabe, W. Kondo, Tatsuhiko Kondo, & Kazuhiro Irie. (2025). 3,4‐Dihydroquinolizinium Ring, the Core Structure of Quinocidin, as a Cysteine‐Selective Electrophile. ChemPlusChem. 90(7). e202500149–e202500149.

Kageyama, Yusuke, Takahisa Nakayama, Daita Kaneda, et al.. (2025). Identification of the binding site and immunoreactivity of anti-Aβ antibody 11A1: Comparison with the toxic conformation-specific TxCo-1 antibody. Biochemical and Biophysical Research Communications. 758. 151655–151655.

Uta, Daisuke, et al.. (2023). Chronic Treatment with Aβ42 with a Toxic Conformer and LPS Induces Inflammatory Responses in BV-2 Microglia with Dysregulation of Hypoxia-Inducible Factor Expression. Biological and Pharmaceutical Bulletin. 46(2). 359–363. 2 indexed citations

Tooyama, Ikuo, Tomoko Kato, Hiroyasu Taguchi, et al.. (2023). Visualization of Amyloid Oligomers in the Brain of Patients with Alzheimer’s Disease. ACTA HISTOCHEMICA ET CYTOCHEMICA. 56(6). 87–94. 3 indexed citations

Murakami, Kazuma, et al.. (2022). Synthetic Biology-Based Discovery of Diterpenoid Pyrones from the Genome of Eupenicillium shearii. Journal of Natural Products. 85(2). 384–390. 10 indexed citations

Murakami, Kazuma, Kazuhiro Irie, Masatoshi Murai, et al.. (2020). Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones. Nature Communications. 11(1). 1830–1830. 80 indexed citations

Imamura, Tomohiro, Yasumasa Ohyagi, Norimichi Nakamura, et al.. (2020). Insulin deficiency promotes formation of toxic amyloid-β42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model. Neurobiology of Disease. 137. 104739–104739. 45 indexed citations

Murakami, Kazuma, Yayoi Obata, Haruka Ueda, et al.. (2020). An RNA aptamer with potent affinity for a toxic dimer of amyloid β42 has potential utility for histochemical studies of Alzheimer's disease. Journal of Biological Chemistry. 295(15). 4870–4880. 20 indexed citations

Nishino, Katsutoshi, Akira Hirasawa, Yusaku Miyamae, et al.. (2019). Stimulation of insulin secretion by acetylenic fatty acids in insulinoma MIN6 cells through FFAR1. Biochemical and Biophysical Research Communications. 522(1). 68–73. 7 indexed citations

10.

Ohnishi, Kohta, et al.. (2016). Possible Contribution of Zerumbone-Induced Proteo-Stress to Its Anti-Inflammatory Functions via the Activation of Heat Shock Factor 1. PLoS ONE. 11(8). e0161282–e0161282. 17 indexed citations

11.

Irie, Kazuhiro, Alister Scott, & Norio Hasegawa. (2014). Investigation of the Detection Ability of an Intrinsic Fluorescence-Based Bioaerosol Detection System for Heat-Stressed Bacteria. PDA Journal of Pharmaceutical Science and Technology. 68(5). 478–493. 2 indexed citations

12.

Sato, Mizuho, Kazuma Murakami, Mayumi Uno, et al.. (2013). Site-specific Inhibitory Mechanism for Amyloid β42 Aggregation by Catechol-type Flavonoids Targeting the Lys Residues. Journal of Biological Chemistry. 288(32). 23212–23224. 197 indexed citations

13.

Sato, Mizuho, Kazuma Murakami, Mayumi Uno, et al.. (2013). Structure–Activity Relationship for (+)-Taxifolin Isolated from Silymarin as an Inhibitor of Amyloid β Aggregation. Bioscience Biotechnology and Biochemistry. 77(5). 1100–1103. 46 indexed citations

14.

Sekiguchi, Hirotaka, Fumiyo Takabayashi, Kazuhiro Irie, & Akira Murakami. (2012). Auraptene Attenuates Gastritis via Reduction of Helicobacter pylori Colonization and Pro-Inflammatory Mediator Production in C57BL/6 Mice. Journal of Medicinal Food. 15(7). 658–663. 20 indexed citations

15.

Nakagawa, Yu, Ryo C. Yanagita, Akira Murakami, et al.. (2011). Synthesis and Biological Evaluation of the 12,12-Dimethyl Derivative of Aplog-1, an Anti-Proliferative Analog of Tumor-Promoting Aplysiatoxin. Bioscience Biotechnology and Biochemistry. 75(6). 1167–1173. 11 indexed citations

16.

Takahashi, Masakazu, Yuta Sugiyama, Kyuichi Kawabata, et al.. (2011). 1,2-Di-O-α-linolenoyl-3-O-β-galactosyl-sn-glycerol as a Superoxide Generation Inhibitor fromPerilla frutescensvar.crispa. Bioscience Biotechnology and Biochemistry. 75(11). 2240–2242. 9 indexed citations

17.

Shindo, Mayumi, Kazuhiro Irie, Hiroyuki Fukuda, & Hajime Ohigashi. (2003). Analysis of the non-covalent interaction between metal ions and the cysteine-Rich domain of protein kinase C eta by electrospray ionization mass spectrometry. Bioorganic & Medicinal Chemistry. 11(23). 5075–5082. 11 indexed citations

18.

Irie, Kazuhiro, Yu Nakagawa, Hajime Ohigashi, et al.. (2001). Selective Binding of Tumor Promoters to the Novel PKC C1B Domains. 2000. 197–200. 1 indexed citations

19.

Nakagawa, Yu, Kazuhiro Irie, Yoshimasa Nakamura, Hajime Ohigashi, & Hideo Hayashi. (1997). Synthesis and Biological Activities of Indolactone-V, the Lactone Analogue of the Tumor Promoter (–)-Indolactam-V. Bioscience Biotechnology and Biochemistry. 61(8). 1415–1417. 4 indexed citations

20.

Irie, Kazuhiro, et al.. (1987). New Teleocidin-related Metabolites from Streptoverticillium blastmyceticum Producing Tumor-promoting Indole Alkaloids(Organic Chemistry). Agricultural and Biological Chemistry. 51(1). 285–287. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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