Kazuhiko Igarashi

31.0k total citations · 7 hit papers
269 papers, 24.5k citations indexed

About

Kazuhiko Igarashi is a scholar working on Molecular Biology, Immunology and Oncology. According to data from OpenAlex, Kazuhiko Igarashi has authored 269 papers receiving a total of 24.5k indexed citations (citations by other indexed papers that have themselves been cited), including 190 papers in Molecular Biology, 56 papers in Immunology and 27 papers in Oncology. Recurrent topics in Kazuhiko Igarashi's work include Heme Oxygenase-1 and Carbon Monoxide (56 papers), Immune Cell Function and Interaction (27 papers) and Epigenetics and DNA Methylation (27 papers). Kazuhiko Igarashi is often cited by papers focused on Heme Oxygenase-1 and Carbon Monoxide (56 papers), Immune Cell Function and Interaction (27 papers) and Epigenetics and DNA Methylation (27 papers). Kazuhiko Igarashi collaborates with scholars based in Japan, United States and United Kingdom. Kazuhiko Igarashi's co-authors include Masayuki Yamamoto, Ken Itoh, Yasutake Katoh, Tetsuro Ishii, Norio Hayashi, Tomoki Chiba, James Douglas Engel, Nobunao Wakabayashi, Akihiko Muto and Satoru Takahashi and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Kazuhiko Igarashi

262 papers receiving 24.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

1997 3.4k citations Ken Itoh, Kazuhiko Igarashi et al. profile →
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

1999 3.0k citations Ken Itoh, Yasutake Katoh et al. profile →
Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2

2004 1.8k citations Kazuhiko Igarashi, Masayuki Yamamoto et al. Molecular and Cellular Biology profile →
Impaired glucose tolerance is a risk factor for cardiovascular disease, but not impaired fasting glucose. The Funagata Diabetes Study.

1999 918 citations Kazuhiko Igarashi et al. profile →
A Third Recognition Element in Bacterial Promoters: DNA Binding by the α Subunit of RNA Polymerase

1993 665 citations Kazuhiko Igarashi et al. profile →
Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene

2002 556 citations Jiying Sun, Hideto Hoshino et al. profile →
Bach Proteins Belong to a Novel Family of BTB-Basic Leucine Zipper Transcription Factors That Interact with MafK and Regulate Transcription through the NF-E2 Site

1996 548 citations Ken Itoh, Hozumi Motohashi et al. Molecular and Cellular Biology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Kazuhiko Igarashi Japan	69	18.3k	3.6k	2.1k	2.1k	1.8k	269	24.5k
Makoto Suematsu Japan	77	10.6k 0.6×	3.0k 0.8×	1.3k 0.6×	2.2k 1.1×	3.3k 1.8×	474	22.6k
Makoto Murakami Japan	72	9.2k 0.5×	3.3k 0.9×	3.0k 1.4×	2.1k 1.0×	2.4k 1.3×	429	19.0k
Shinya Toyokuni Japan	80	11.0k 0.6×	1.8k 0.5×	2.2k 1.0×	2.6k 1.3×	1.5k 0.8×	435	23.9k
Akiyoshi Fukamizu Japan	75	10.8k 0.6×	1.6k 0.4×	1.8k 0.8×	1.1k 0.6×	2.3k 1.3×	365	20.9k
John D. Hayes United Kingdom	84	27.9k 1.5×	1.7k 0.5×	1.8k 0.9×	3.2k 1.5×	2.2k 1.2×	262	37.1k
Stephen M. Prescott United States	89	9.1k 0.5×	6.1k 1.7×	2.5k 1.2×	2.7k 1.3×	2.4k 1.3×	233	25.6k
Santos A. Susín France	74	21.6k 1.2×	4.4k 1.2×	858 0.4×	2.3k 1.1×	1.8k 1.0×	142	29.0k
Hozumi Motohashi Japan	61	16.4k 0.9×	2.3k 0.6×	682 0.3×	2.2k 1.1×	1.8k 1.0×	175	22.9k
Naoufal Zamzami France	67	20.9k 1.1×	4.2k 1.2×	913 0.4×	2.3k 1.1×	1.8k 1.0×	92	28.2k
Shaker A. Mousa United States	73	9.6k 0.5×	1.8k 0.5×	1.2k 0.5×	2.7k 1.3×	1.2k 0.7×	665	24.6k

Countries citing papers authored by Kazuhiko Igarashi

Since Specialization

Citations

This map shows the geographic impact of Kazuhiko Igarashi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kazuhiko Igarashi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kazuhiko Igarashi more than expected).

Fields of papers citing papers by Kazuhiko Igarashi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kazuhiko Igarashi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kazuhiko Igarashi. The network helps show where Kazuhiko Igarashi may publish in the future.

Co-authorship network of co-authors of Kazuhiko Igarashi

This figure shows the co-authorship network connecting the top 25 collaborators of Kazuhiko Igarashi. A scholar is included among the top collaborators of Kazuhiko Igarashi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kazuhiko Igarashi. Kazuhiko Igarashi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Matsumoto, Mitsuyo, Miki Watanabe‐Matsui, Tadashi Nakagawa, et al.. (2024). TANK Binding Kinase 1 Promotes BACH1 Degradation through Both Phosphorylation-Dependent and -Independent Mechanisms without Relying on Heme and FBXO22. International Journal of Molecular Sciences. 25(8). 4141–4141. 2 indexed citations

Nishizawa, Hironari, Guan Chen, Mitsuyo Matsumoto, et al.. (2024). Intracellular biliverdin dynamics during ferroptosis. The Journal of Biochemistry. 176(6). 472–483.

Niihori, Tetsuya, Akihiko Muto, Yoshikazu Hayashi, et al.. (2023). Mecom mutation related to radioulnar synostosis with amegakaryocytic thrombocytopenia reduces HSPCs in mice. Blood Advances. 7(18). 5409–5420. 2 indexed citations

Alam, Mahabub, Hiroki Shima, Yoshitaka Matsuo, et al.. (2022). mTORC1-independent translation control in mammalian cells by methionine adenosyltransferase 2A and S-adenosylmethionine. Journal of Biological Chemistry. 298(7). 102084–102084. 8 indexed citations

Cai, Lun, Ali S. Arbab, Tae Jin Lee, et al.. (2022). BACH1-Hemoxygenase-1 axis regulates cellular energetics and survival following sepsis. Free Radical Biology and Medicine. 188. 134–145. 19 indexed citations

Satō, Masaki, Mitsuyo Matsumoto, Yuriko Saiki, et al.. (2020). BACH1 Promotes Pancreatic Cancer Metastasis by Repressing Epithelial Genes and Enhancing Epithelial–Mesenchymal Transition. Cancer Research. 80(6). 1279–1292. 82 indexed citations

Shima, Hiroki, et al.. (2019). Haploinsufficient tumor suppressor Tip60 negatively regulates oncogenic Aurora B kinase. Journal of Biosciences. 44(6). 9 indexed citations

Kishimoto, Daiga, Yohei Kirino, Maasa Tamura, et al.. (2018). Dysregulated heme oxygenase-1low M2-like macrophages augment lupus nephritis via Bach1 induced by type I interferons. Arthritis Research & Therapy. 20(1). 64–64. 39 indexed citations

Nar, Rukiye, Álex Pérez, Masatoshi Ikeda, et al.. (2018). Identification of a Novel Enhancer/Chromatin Opening Element Associated with High-Level γ -Globin Gene Expression. Molecular and Cellular Biology. 38(19). 4 indexed citations

10.

Ito, Masato, Nobuhiko Nagano, Ryo Ogawa, et al.. (2017). Genetic ablation of Bach1 gene enhances recovery from hyperoxic lung injury in newborn mice via transient upregulation of inflammatory genes. Pediatric Research. 81(6). 926–931. 17 indexed citations

11.

Kasuga, Kie, Yasutake Katoh, Keisuke Nagase, & Kazuhiko Igarashi. (2017). Microproteomics with microfluidic‐based cell sorting: Application to 1000 and 100 immune cells. PROTEOMICS. 17(13-14). 23 indexed citations

12.

Kobayashi, Masahiro, Hiroki Kato, Ari Itoh‐Nakadai, et al.. (2016). Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency. Haematologica. 102(3). 454–465. 23 indexed citations

13.

Watanabe‐Matsui, Miki, Tamami Uejima, Hiroki Shima, et al.. (2016). Charge-state-distribution analysis of Bach2 intrinsically disordered heme binding region. The Journal of Biochemistry. 160(5). 291–298. 15 indexed citations

14.

Maéda, Hiroshi, Youhei Yamagata, Kazutaka Murayama, et al.. (2015). Synergistic Effect of Neutral Protease and Clostripain on Rat Pancreatic Islet Isolation. Transplantation. 99(7). 1349–1355. 20 indexed citations

15.

Takada, Tsuyoshi, Shigeru Miyaki, Hiroyuki Ishitobi, et al.. (2015). Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1. Arthritis Research & Therapy. 17(1). 285–285. 68 indexed citations

16.

Brydun, Andrey, et al.. (2014). Bach1Deficiency and Accompanying Overexpression of Heme Oxygenase-1 Do Not Influence Aging or Tumorigenesis in Mice. Oxidative Medicine and Cellular Longevity. 2014. 1–12. 23 indexed citations

17.

Watanabe‐Matsui, Miki, Takashi Matsumoto, Toshitaka Matsui, et al.. (2014). Heme binds to an intrinsically disordered region of Bach2 and alters its conformation. Archives of Biochemistry and Biophysics. 565. 25–31. 35 indexed citations

18.

Ohbayashi, Naomi, Takashi Matsumoto, Hiroki Shima, et al.. (2013). Solution Structure of Clostridial Collagenase H and Its Calcium-Dependent Global Conformation Change. Biophysical Journal. 104(7). 1538–1545. 19 indexed citations

19.

Inoue, Motoki, Susumu Tazuma, Keishi Kanno, et al.. (2010). Bach1 gene ablation reduces steatohepatitis in mouse MCD diet model. Journal of Clinical Biochemistry and Nutrition. 48(2). 161–166. 40 indexed citations

20.

Itoh, Ken, Hozumi Motohashi, Norio Hayashi, et al.. (1996). Bach Proteins Belong to a Novel Family of BTB-Basic Leucine Zipper Transcription Factors That Interact with MafK and Regulate Transcription through the NF-E2 Site. Molecular and Cellular Biology. 16(11). 6083–6095. 548 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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