James Douglas Engel

23.4k total citations · 3 hit papers
225 papers, 19.0k citations indexed

About

James Douglas Engel is a scholar working on Molecular Biology, Genetics and Genetics. According to data from OpenAlex, James Douglas Engel has authored 225 papers receiving a total of 19.0k indexed citations (citations by other indexed papers that have themselves been cited), including 192 papers in Molecular Biology, 40 papers in Genetics and 28 papers in Genetics. Recurrent topics in James Douglas Engel's work include Epigenetics and DNA Methylation (64 papers), Genomics and Chromatin Dynamics (58 papers) and RNA modifications and cancer (38 papers). James Douglas Engel is often cited by papers focused on Epigenetics and DNA Methylation (64 papers), Genomics and Chromatin Dynamics (58 papers) and RNA modifications and cancer (38 papers). James Douglas Engel collaborates with scholars based in United States, Japan and Netherlands. James Douglas Engel's co-authors include Masayuki Yamamoto, Ken Itoh, Nobunao Wakabayashi, Tetsuro Ishii, Kazuhiko Igarashi, Yasutake Katoh, Hozumi Motohashi, Jerry B. Dodgson, Fumiki Katsuoka and Mark Leonard and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

James Douglas Engel

222 papers receiving 18.6k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

1999 3.0k citations James Douglas Engel, Masayuki Yamamoto et al. profile →
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

2003 728 citations Hozumi Motohashi, Satoru Takahashi et al. profile →
Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis

1995 500 citations Mark Leonard, James Douglas Engel et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
James Douglas Engel United States	72	14.5k	2.6k	2.3k	2.1k	1.9k	225	19.0k
Yoshihide Tsujimoto Japan	85	18.8k 1.3×	1.4k 0.6×	4.0k 1.7×	2.1k 1.0×	981 0.5×	184	28.6k
Lorenzo A. Pinna Italy	74	15.9k 1.1×	1.6k 0.6×	1.4k 0.6×	1.5k 0.7×	1.1k 0.5×	448	21.6k
Yuet Wai Kan United States	75	12.1k 0.8×	2.8k 1.1×	1.1k 0.5×	4.8k 2.3×	3.3k 1.7×	215	19.6k
Keiko Nakayama Japan	71	15.7k 1.1×	1.8k 0.7×	3.7k 1.6×	1000 0.5×	1.0k 0.5×	286	23.3k
Alberto M. Martelli Italy	71	12.7k 0.9×	822 0.3×	1.7k 0.7×	1.1k 0.5×	2.2k 1.2×	417	19.2k
Philip N. Tsichlis United States	71	14.4k 1.0×	2.0k 0.8×	4.9k 2.2×	944 0.5×	777 0.4×	196	21.5k
Shigeru Chiba Japan	59	6.8k 0.5×	1.2k 0.5×	3.5k 1.5×	1.3k 0.6×	2.9k 1.5×	404	15.8k
Paul A. Marks United States	72	17.9k 1.2×	1.5k 0.6×	1.3k 0.6×	1.8k 0.9×	2.2k 1.1×	202	22.6k
Christoph W. Turck Germany	64	9.4k 0.7×	1.2k 0.5×	2.6k 1.1×	827 0.4×	987 0.5×	247	16.0k
Philip W. Majerus United States	88	11.3k 0.8×	1.6k 0.6×	1.6k 0.7×	1.7k 0.8×	4.5k 2.4×	231	22.9k

Countries citing papers authored by James Douglas Engel

Since Specialization

Citations

This map shows the geographic impact of James Douglas Engel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James Douglas Engel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James Douglas Engel more than expected).

Fields of papers citing papers by James Douglas Engel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James Douglas Engel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James Douglas Engel. The network helps show where James Douglas Engel may publish in the future.

Co-authorship network of co-authors of James Douglas Engel

This figure shows the co-authorship network connecting the top 25 collaborators of James Douglas Engel. A scholar is included among the top collaborators of James Douglas Engel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James Douglas Engel. James Douglas Engel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Drysdale, Claire, Lei Yu, Beth McGee, et al.. (2025). p27Kip1 regulates γ-globin production. Blood. 147(9). 973–986.

King, Richard A., Ann Friedman, Guojing Zhu, et al.. (2021). SEC23A rescues SEC23B-deficient congenital dyserythropoietic anemia type II. Science Advances. 7(48). eabj5293–eabj5293. 13 indexed citations

Yu, Lei, Philippe Lemay, Morgan Jones, et al.. (2021). A new murine Rpl5 ( uL18 ) mutation provides a unique model of variably penetrant Diamond-Blackfan anemia. Blood Advances. 5(20). 4167–4178. 3 indexed citations

Abe, Makoto, et al.. (2021). GATA3 is essential for separating patterning domains during facial morphogenesis. Development. 148(17). 9 indexed citations

Mahamud, Md. Riaj, Xin Geng, Yen‐Chun Ho, et al.. (2019). GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126. Development. 146(21). 34 indexed citations

Welsh, John D., Mark H. Hoofnagle, Sharika Bamezai, et al.. (2019). Hemodynamic regulation of perivalvular endothelial gene expression prevents deep venous thrombosis. Journal of Clinical Investigation. 129(12). 5489–5500. 40 indexed citations

Rivers, Angela, Kestis Vaitkus, Ramasamy Jagadeeswaran, et al.. (2018). Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboons. Experimental Hematology. 67. 60–64.e2. 18 indexed citations

Moriguchi, Takashi, Tomofumi Hoshino, Arvind Rao, et al.. (2018). A Gata3 3′ Distal Otic Vesicle Enhancer Directs Inner Ear-Specific Gata3 Expression. Molecular and Cellular Biology. 38(21). 9 indexed citations

Lim, Kim-Chew, Tomonori Hosoya, William D. Brandt, et al.. (2012). Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning. Journal of Clinical Investigation. 122(10). 3705–3717. 116 indexed citations

10.

Maeda, Atsuko, Takashi Moriguchi, Michito Hamada, et al.. (2009). Transcription factor GATA‐3 is essential for lens development. Developmental Dynamics. 238(9). 2280–2291. 39 indexed citations

11.

Rao, Arvind, Alfred O. Hero, David J. States, & James Douglas Engel. (2007). Motif Discovery in Tissue-Specific Regulatory Sequences Using Directed Information. PubMed. 2007. 1–13. 15 indexed citations

12.

Mitchell, Jennifer A., Lyubomira Chakalova, Beatriz Goyenechea, et al.. (2007). Intergenic Transcription, Cell-Cycle and the Developmentally Regulated Epigenetic Profile of the Human Beta-Globin Locus. PLoS ONE. 2(7). e630–e630. 39 indexed citations

13.

Hasegawa, Susan L., Takashi Moriguchi, Arvind Rao, et al.. (2006). Dosage-dependent rescue of definitive nephrogenesis by a distant Gata3 enhancer. Developmental Biology. 301(2). 568–577. 30 indexed citations

14.

Ness, Scott A. & James Douglas Engel. (1994). Vintage reds and whites: combinatorial transcription factor utilization in hematopoietic differentiation. Current Opinion in Genetics & Development. 4(5). 718–724. 48 indexed citations

15.

Yang, Zhuoying, Lin Gu, Paul‐Henri Roméo, et al.. (1994). Human GATA-3 trans-Activation , DNA-Binding, and Nuclear Localization Activities Are Organized into Distinct Structural Domains. Molecular and Cellular Biology. 14(3). 2201–2212. 27 indexed citations

16.

Chiba, Tomoki, Yasunobu Nagata, Kazuhiro Sakamaki, et al.. (1993). Induction of erythroid-specific gene expression in lymphoid cells.. Proceedings of the National Academy of Sciences. 90(24). 11593–11597. 68 indexed citations

17.

Engel, James Douglas, et al.. (1993). DNA-Binding Specificities of the GATA Transcription Factor Family. Molecular and Cellular Biology. 13(7). 4011–4022. 494 indexed citations

18.

Foley, Kevin P., Mark Leonard, & James Douglas Engel. (1993). Quantitation of RNA using the polymerase chain reaction. Trends in Genetics. 9(11). 380–385. 196 indexed citations

19.

Yamamoto, Masayuki, et al.. (1991). Murine and Human T-Lymphocyte GATA-3 Factors Mediate Transcription through a cis -Regulatory Element within the Human T-Cell Receptor δ Gene Enhancer. Molecular and Cellular Biology. 11(5). 2778–2784. 73 indexed citations

20.

Trainor, Cecelia D., et al.. (1986). A Single Amino Acid Substitution in v- erbB Confers a Thermolabile Phenotype to ts 167 Avian Erythroblastosis Virus-Transformed Erythroid Cells. Molecular and Cellular Biology. 6(5). 1751–1759. 18 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact