Karen E. Chapman

11.3k citations

148 papers · 9.0k indexed · 3 hit papers · h-index 47

Impact in

Behavioral Neuroscience top 0.2%
- Stress Responses and Cortisol
Endocrinology, Diabetes and Metabolism top 0.2%
- Hormonal Regulation and Hypertension
- Adrenal Hormones and Disorders

Papers in

Endocrinology, Diabetes and Metabolism 93
- Hormonal Regulation and Hypertension 88
- Adrenal Hormones and Disorders 26
Behavioral Neuroscience 16
- Stress Responses and Cortisol 16

Co-authors: Jonathan R. Seckl Agnes E. Coutinho Megan C. Holmes Christopher R.W. Edwards Stephen R. Lord B. Munro Anne Tiedemann Pauline Jamieson
Journals: Journal of Endocrinology (16 papers)Endocrinology (11 papers)Journal of Molecular Endocrinology (6 papers)Molecular and Cellular Endocrinology (5 papers)The Journal of Steroid Biochemistry and Molecular Biology (4 papers)
Partner nations: United Kingdom United States Japan

In The Last Decade

Karen E. Chapman

146 papers receiving 8.8k citations

Hit Papers

align trajectories log scale

11β-Hydroxysteroid Dehydrogenases: Intracellular Gate-Keepers of Tissue Glucocorticoid Action 2013 · 630 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2013 Physiological Reviews
2010 Molecular and Cellular Endocrinology
2002 The Journals of Gerontology Series A

Peers

Countries citing papers authored by Karen E. Chapman

Since Specialization

Citations

This map shows the geographic impact of Karen E. Chapman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Karen E. Chapman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Karen E. Chapman more than expected).

Fields of papers citing papers by Karen E. Chapman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Karen E. Chapman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Karen E. Chapman. The network helps show where Karen E. Chapman may publish in the future.

Co-authors

The 25 scholars most cited alongside Karen E. Chapman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Karen E. Chapman Line = papers co-authored together Karen E. Chapman links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Deletion of Hsd11b1 suppresses caloric restriction-induced bone marrow adiposity in male but not female mice Journal of Endocrinology ·厚史中村, Karla J. Suchacki, 성호영, Richard J. Sulston, Robert Wallace, Benjamin J. Thomas, Shaista Zainab, 安西弘行, Gavin J. Macpherson, Nicholas M. Morton, Natalie Homer, Karen E. Chapman, William P. Cawthorn	2024	2
2	Contribution of local regeneration of glucocorticoids to tissue steroid pools Journal of Endocrinology ·Shazia Khan, Dawn E. W. Livingstone, Agnieszka Zielińska, Craig Doig, Diego Cobice, Cristina L. Esteves, F. X. Li, Natalie Homer, J. R. Seckl, C. Logan Mackay, Scott P. Webster, Gareth G. Lavery, Karen E. Chapman, BR Walker, Ruth Andrew	2023	1
3	Reciprocal Regulation of HSD11B1 and HSD11B2 Predicts Glucocorticoid Sensitivity in Childhood Acute Lymphoblastic Leukemia The Journal of Pediatrics ·Annisa Septy Erviani, Cristina L. Esteves, Matheus Albuquerque Montenegro, Kimiyoshi Sakaguchi, ปกรณ์ รัตนสุวรรณ, 博祥山本, Ramesh N. Raizada, Brenda Gibson, Angela Thomas, Karen E. Chapman	2020	5
4	Adrenal hormones mediate disease tolerance in malaria Nature Communications ·Leen Vandermosten, Thao‐Thy Pham, Akashe Bahram, Pascal Lejay, Natacha Lays, Anne P. Cross, Christopher J. Kenyon, Hengsheng Wang, Karen E. Chapman, Frans Schuit, Karolien De Bosscher, Ghislain Opdenakker, Philippe E. Van den Steen	2018	30
5	11β-Hydroxysteroid Dehydrogenases: Intracellular Gate-Keepers of Tissue Glucocorticoid Action Physiological Reviews ·Karen E. Chapman, Megan C. Holmes, Jonathan R. Seckl Hit paper breakdown →	2013	630
6	Pro-Inflammatory Cytokine Induction of 11β-hydroxysteroid Dehydrogenase Type 1 in A549 Cells Requires Phosphorylation of C/EBPβ at Thr235 PLoS ONE ·Cristina L. Esteves, Hengsheng Wang, 莫凤娟, Matheus Albuquerque Montenegro, Annisa Septy Erviani, A. W., F. Xavier Donadeu, Jonathan R. Seckl, Karen E. Chapman	2013	14
7	Modulation of 11β-Hydroxysteroid Dehydrogenase as a Strategy to Reduce Vascular Inflammation Current Atherosclerosis Reports ·Patrick W. F. Hadoke, Tiina Kipari, Jonathan R. Seckl, Karen E. Chapman	2013	30
8	Maturational effects of glucocorticoids on fetal cardiomyocytes are direct and mediated by glucocorticoid receptor Eva A. Rog‐Zielinska, Anya Shen, Megan C. Holmes, Karen E. Chapman	2012	1
9	The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights Molecular and Cellular Endocrinology ·Agnes E. Coutinho, Karen E. Chapman Hit paper breakdown →	2010	1263
10	Overexpression of 5‐HT_2C receptors in forebrain leads to elevated anxiety and hypoactivity European Journal of Neuroscience ·Atsuko Kimura, 农华明, Roderick N. Carter, Gavin MacColl, Karen L. French, J. Paul Simons, Raya Al‐Shawi, Shutao Wu, Karen E. Chapman, Megan C. Holmes	2009	35
11	7-Oxysterols Modulate Glucocorticoid Activity in Adipocytes through Competition for 11β-Hydroxysteroid Dehydrogenase Type Endocrinology ·Małgorzata Wamil, Ruth Andrew, Karen E. Chapman, Jonathan M. Street, Nicholas Morton, Jonathan R. Seckl	2008	37
12	11β-HSD1, Inflammation, Metabolic Disease and Age-related Cognitive (dys)Function Neurochemical Research ·Karen E. Chapman, Jonathan R. Seckl	2007	26
13	Local Amplification of Glucocorticoids by 11β-Hydroxysteroid Dehydrogenase Type 1 Promotes Macrophage Phagocytosis of Apoptotic Leukocytes The Journal of Immunology ·James S. Gilmour, Agnes E. Coutinho, Jean‐François Cailhier, Tak Yung Man, Michael Clay, Graham D. Thomas, Hayley J. Harris, John J. Mullins, Jonathan R. Seckl, John Savill, Karen E. Chapman	2006	119
14	Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11β-hydroxysteroid dehydrogenase type 1 Journal of Molecular Endocrinology ·Iwona Bujalska, Nicole L. Draper, Zoi Michailidou, Jeremy Tomlinson, Perrin C. White, Karen E. Chapman, Elizabeth A. Walker, Paul M. Stewart	2005	144
15	Regulation of gene expression Karen E. Chapman, Stephen J. Higgins	2001	2
16	C/EBP Regulates Hepatic Transcription of 11β-Hydroxysteroid Dehydrogenase Type 1 Journal of Biological Chemistry ·Louise Williams, Val Lyons, Adolph Pichler, Elisabetta D’Errico, Gretchen J. Darlington, Valeria Poli, Jonathan R. Seckl, Karen E. Chapman	2000	101
17	Interactions between oestradiol and glucocorticoid regulatory effects on liver-specific glucocorticoid-inducible genes: possible evidence for a role of hepatic 11beta-hydroxysteroid dehydrogenase type 1 Journal of Endocrinology ·Pauline Jamieson, Moffat Nyirenda, BR Walker, Karen E. Chapman, (unknown)	1999	59
18	Changes in the expression of myometrial ryanodine receptor mRNAs during human pregnancy Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·Cécile Martin, Karen E. Chapman, Steven Thornton, Richard H. Ashley	1999	25
19	Cloning, sequencing and tissue-distribution of mouse 11β-hydroxysteroid dehydrogenase-1 cDNA The Journal of Steroid Biochemistry and Molecular Biology ·Elisabetta D’Errico, Karen E. Chapman, Val Lyons, Pauline Jamieson, John J. Mullins, Christopher R.W. Edwards, Jonathan R. Seckl	1995	55
20	Identification of a High Molecular Weight Steroid Response Element Binding Protein Molecular Endocrinology ·Arif Jahan Sarawer, Karen E. Chapman	1990	2

About Karen E. Chapman

Karen E. Chapman is a scholar working on Endocrinology, Diabetes and Metabolism, Behavioral Neuroscience, Pharmacology, Pediatrics, Perinatology and Child Health and Pharmacology, having authored 148 papers that have together received 9.0k indexed citations. Recurring topics across this work include Hormonal Regulation and Hypertension (88 papers), Adrenal Hormones and Disorders (26 papers), Birth, Development, and Health (20 papers), Apelin-related biomedical research (19 papers), Estrogen and related hormone effects (18 papers), Stress Responses and Cortisol (16 papers), Cardiovascular, Neuropeptides, and Oxidative Stress Research (12 papers) and Adipose Tissue and Metabolism (11 papers). The work is most often cited by research in Behavioral Neuroscience (1.3k citations), Endocrinology, Diabetes and Metabolism (3.6k citations), Physical Therapy, Sports Therapy and Rehabilitation (424 citations), Biological Psychiatry (215 citations) and Pediatrics, Perinatology and Child Health (1.1k citations). Karen E. Chapman has collaborated with scholars based in United Kingdom, United States and Japan. Frequent co-authors include Jonathan R. Seckl, Agnes E. Coutinho, Megan C. Holmes, Christopher R.W. Edwards, Stephen R. Lord, B. Munro, Anne Tiedemann, Pauline Jamieson, J. R. Seckl and Joyce L.W. Yau. Their work appears in journals such as Journal of Endocrinology, Endocrinology, Journal of Molecular Endocrinology, Molecular and Cellular Endocrinology and The Journal of Steroid Biochemistry and Molecular Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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