Kan Chiba

8.6k citations

158 papers · 7.2k indexed · 1 hit paper · h-index 41

Impact in

Pharmacology top 0.02%
- Pharmacogenetics and Drug Metabolism
- Drug-Induced Hepatotoxicity and Protection
- Cholinesterase and Neurodegenerative Diseases
Oncology top 1%
- Drug Transport and Resistance Mechanisms

Papers in

Pharmacology 75
- Pharmacogenetics and Drug Metabolism 74
- Cholinesterase and Neurodegenerative Diseases 12
Oncology 55
- Drug Transport and Resistance Mechanisms 50

Co-authors: Kaoru Kobayashi Anthony J. Trevor Takashi Ishizaki Neal Castagnoli Masakiyo Hosokawa Noriaki Shimada Tomomi Furihata Takahiro Kubota
Journals: Drug Metabolism and Pharmacokinetics (19 papers)Drug Metabolism and Disposition (17 papers)Clinical Pharmacology & Therapeutics (7 papers)Therapeutic Drug Monitoring (5 papers)The Journal of Pediatrics (5 papers)
Partner nations: Japan United States South Korea

In The Last Decade

Kan Chiba

156 papers receiving 6.9k citations

Hit Papers

align trajectories log scale

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase 1984 · 925 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1984 Biochemical and Biophysical Research Communications

Peers

Countries citing papers authored by Kan Chiba

Since Specialization

Citations

This map shows the geographic impact of Kan Chiba's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kan Chiba with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kan Chiba more than expected).

Fields of papers citing papers by Kan Chiba

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kan Chiba. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kan Chiba. The network helps show where Kan Chiba may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Kan Chiba, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Kan Chiba Line = papers co-authored together Kan Chiba links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Identification of novel glutathione adducts of benzbromarone in human liver microsomes Drug Metabolism and Pharmacokinetics ·D. Baweja, Kaoru Kobayashi, Sanghoon Sim, Noriyuki Kogure, Hiromitsu Takayama, Kan Chiba	2016	10
2	Involvement of ESE-3, epithelial-specific ETS factor family member 3, in transactivation of the ABCB1 gene via pregnane X receptor in intestine-derived LS180 cells but not in liver-derived HepG2 cells Drug Metabolism and Pharmacokinetics ·Naoya Kameyama, Kaoru Kobayashi, Shoko Shimizu, Yuki Yamasaki, Mika Endo, Mari Hashimoto, Tomomi Furihata, Kan Chiba	2016	5
3	Cancer-Type Organic Anion Transporting Polypeptide 1B3: Current Knowledge of the Gene Structure, Expression Profile, Functional Implications and Future Perspectives Current Drug Metabolism ·Tomomi Furihata, Yuchen Sun, Kan Chiba	2015	15
4	Differential inhibition features of direct-acting anti-hepatitis C virus agents against human organic anion transporting polypeptide 2B1 International Journal of Antimicrobial Agents ·Tomomi Furihata, S. A. Pakeman, Yuki Suzuki, Shogo Matsumoto, Octavio Cordova-Arevalo, Akihito Tsubota, Sayaka Matsumoto, Kan Chiba	2015	6
5	Identification of a new organic anion transporting polypeptide 1B3 mRNA isoform primarily expressed in human cancerous tissues and cells Biochemical and Biophysical Research Communications ·Miki Nagai, Tomomi Furihata, Sayaka Matsumoto, K. Kuchitsu, Shinichiro Motohashi, Ichiro Yoshino, B. Planque, Atsushi Miyajima, Shogo Matsumoto, Kan Chiba	2012	56
6	Species Differences in Mechanism-Based Inactivation of CYP3A in Humans, Rats and Mice Drug Metabolism and Pharmacokinetics ·Sasitorn Aueviriyavit, Kaoru Kobayashi, Kan Chiba	2010	17
7	Hepatocyte Nuclear Factor 1 Alpha is a Factor Responsible for the Interindividual Variation of OATP1B1 mRNA Levels in Adult Japanese Livers Pharmaceutical Research ·Tomomi Furihata, P Piovanello, Naoko Yamamoto, Kaoru Kobayashi, Kan Chiba	2007	21
8	Hepatocyte nuclear factor-4α plays pivotal roles in the regulation of mouse carboxylesterase 2 gene transcription in mouse liver Archives of Biochemistry and Biophysics ·Tomomi Furihata, Masakiyo Hosokawa, Ming-Chien Hou, Tetsuo Satoh, Kan Chiba	2006	32
9	Dexamethasone-induced methylprednisolone hemisuccinate hydrolase: Its identification as a member of the rat carboxylesterase 2 family and its unique existence in plasma Biochemical Pharmacology ·Tomomi Furihata, Masakiyo Hosokawa, Ayako Fujii, Jianixn Wu, Tetsuo Satoh, Kan Chiba	2005	37
10	Allelic expression imbalance of the human CYP3A4 gene and individual phenotypic status Human Molecular Genetics ·Takeshi Hirota, Ichiro Ieiri, Hiroshi Takane, Shinji Maegawa, Masakiyo Hosokawa, Kaoru Kobayashi, Kan Chiba, Eiji Nanba, Mitsuo Oshimura, Tetsuo Satō, Shun Higuchi, Kenji Otsubo	2004	41
11	A Novel Single Nucleotide Polymorphism (SNP) of the CYP2C19 Gene in a Japanese Subject with Lowered Capacity of Mephobarbital 4′-Hydroxylation Drug Metabolism and Pharmacokinetics ·Jun Morita, Kaoru Kobayashi, Diana Alejandra Posada Muñoz, Miyuki Kimura, Shin Irie, Takashi Ishizaki, Kan Chiba	2004	26
12	IDENTIFICATION OF DI-(2-ETHYLHEXYL) PHTHALATE-INDUCED CARBOXYLESTERASE 1 IN C57BL/6 MOUSE LIVER MICROSOMES: PURIFICATION, CDNA CLONING, AND BACULOVIRUS-MEDIATED EXPRESSION Drug Metabolism and Disposition ·Tomomi Furihata, Masakiyo Hosokawa, (unknown), Takahiro Nakamura, Tetsuo Satoh, Kan Chiba	2004	22
13	CYP Isoforms Involved in the Metabolism of Clarithromycin in vitro: Comparison between the Identification from Disappearance Rate and that from Formation Rate of Metabolites Drug Metabolism and Pharmacokinetics ·Akio Suzuki, Izumi Iida, Reshetnikova Elena Vasilevna, Masayuki Akimoto, Shohei Higuchi, پیمان علیمرادی, Masayoshi Tani, Takashi Ishizaki, Kan Chiba	2003	26
14	Cyp3a4 Inducible Model For In Vitro Analysis of Human Drug Metabolism Using A Bioartificial Liver Hepatology ·Kayla Livingston, Tomokazu Matsuura, Anne Froidevaux, L. Jané Cabré, Masaya Saito, Masakiyo Hosokawa, Kan Chiba, Takahiro Masaki, Hideki Aizaki, Kiyoshi Ohkawa, Karina Asheim	2003	54
15	cDNA cloning, characterization and stable expression of novel human brain carboxylesterase FEBS Letters ·Liliana Hincapié Henao, Masakiyo Hosokawa, Yuko Ogasawara, Helciene Moreira Dias, Kan Chiba	1999	62
16	Identification of Cytochrome P450 Isoforms Involved in Citalopram N-Demethylation by Human Liver Microsomes Journal of Pharmacology and Experimental Therapeutics ·Kaoru Kobayashi, Kan Chiba, 林润雄 Lin Runxiong, Tsutomu Shimada, Yu Chang, Toru Horie, Masayoshi Tani, Toshinori Yamamoto, Takashi Ishizaki, Yukio Kuroiwa	1997	117
17	Single-Dose Pharmacokinetics and Pharmacodynamics of Oral Triazolam in Relation to Cytochrome P4502C19 (CYP2C19) Activity Therapeutic Drug Monitoring ·Norio Yasui, Koichi Otani, Tadashi Ohkubo, Takako Osanai, Kazunobu Sugawara, Kan Chiba, Takashi Ishizaki, Sunao Kaneko	1997	7
18	Development and preliminary application of high-performance liquid chromatographic assay of urinary metabolites of diazepam in humans Journal of Chromatography B Biomedical Sciences and Applications ·Kan Chiba, A. D. Bartal, 矢野峰生, Yuriko Kato, Takayuki Hirano, Takashi Ishizaki	1995	27
19	The kinetic profiles of enalapril and enalaprilat and their possible developmental changes in pediatric patients with congestive heart failure Clinical Pharmacology & Therapeutics ·Hidefumi Nakamura, Masahiro Ishii, T. Sugimura, Kan Chiba, Hirohisa Kato, Takashi Ishizaki	1994	23
20	Normality of product spaces and Morita's conjectures Topology and its Applications ·Kan Chiba, Teodor C. Przymusiński, Mary Ellen Rudin	1986	6

About Kan Chiba

Kan Chiba is a scholar working on Pharmacology, Oncology, Biochemistry, Clinical Biochemistry and Pharmacology, having authored 158 papers that have together received 7.2k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (74 papers), Drug Transport and Resistance Mechanisms (50 papers), Pharmacological Effects and Toxicity Studies (14 papers), Eicosanoids and Hypertension Pharmacology (12 papers), Metabolism and Genetic Disorders (12 papers), Cholinesterase and Neurodegenerative Diseases (12 papers), Analytical Chemistry and Chromatography (11 papers) and Epilepsy research and treatment (11 papers). The work is most often cited by research in Pharmacology (2.8k citations), Oncology (2.0k citations), Pharmacology (1.0k citations), Biochemistry (425 citations) and Neurology (888 citations). Kan Chiba has collaborated with scholars based in Japan, United States and South Korea. Frequent co-authors include Kaoru Kobayashi, Anthony J. Trevor, Takashi Ishizaki, Neal Castagnoli, Masakiyo Hosokawa, Noriaki Shimada, Tomomi Furihata, Takahiro Kubota, Neal Castagnoli and Masayoshi Tani. Their work appears in journals such as Drug Metabolism and Pharmacokinetics, Drug Metabolism and Disposition, Clinical Pharmacology & Therapeutics, Therapeutic Drug Monitoring and The Journal of Pediatrics.

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