Joshua J. Gruber

3.3k total citations · 2 hit papers
33 papers, 2.3k citations indexed

About

Joshua J. Gruber is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Joshua J. Gruber has authored 33 papers receiving a total of 2.3k indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Molecular Biology, 12 papers in Oncology and 9 papers in Cancer Research. Recurrent topics in Joshua J. Gruber's work include RNA Research and Splicing (7 papers), DNA Repair Mechanisms (5 papers) and Cancer Immunotherapy and Biomarkers (5 papers). Joshua J. Gruber is often cited by papers focused on RNA Research and Splicing (7 papers), DNA Repair Mechanisms (5 papers) and Cancer Immunotherapy and Biomarkers (5 papers). Joshua J. Gruber collaborates with scholars based in United States, Canada and Australia. Joshua J. Gruber's co-authors include Craig B. Thompson, M. Celeste Simon, Uma M. Sachdeva, Justin R. Cross, Patrick S. Ward, Raymond G. Dematteo, Jesse M. Platt, Jessica E.S. Shay, David R. Wise and M Snyder and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Nature Communications.

In The Last Decade

Joshua J. Gruber

32 papers receiving 2.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability

2011 791 citations David R. Wise, Patrick S. Ward et al. Proceedings of the National Academy of Sciences profile →
Short-chain fatty acid metabolites propionate and butyrate are unique epigenetic regulatory elements linking diet, metabolism and gene expression

2025 42 citations Michael Nshanian, Joshua J. Gruber et al. Nature Metabolism profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Joshua J. Gruber United States	20	1.6k	1.0k	367	253	163	33	2.3k
Yijun Huang China	18	1.7k 1.0×	1.1k 1.1×	676 1.8×	270 1.1×	108 0.7×	39	2.5k
Laurent Vallar Luxembourg	27	1.4k 0.9×	809 0.8×	368 1.0×	378 1.5×	207 1.3×	60	2.4k
Štefan Kaluz United States	25	1.2k 0.8×	830 0.8×	275 0.7×	209 0.8×	113 0.7×	57	1.9k
Luc Furic Australia	28	2.4k 1.5×	465 0.5×	341 0.9×	257 1.0×	158 1.0×	48	3.0k
Debangshu Samanta United States	16	1.8k 1.1×	1.3k 1.3×	676 1.8×	469 1.9×	118 0.7×	19	2.7k
Jasper Mullenders Netherlands	17	2.0k 1.3×	440 0.4×	651 1.8×	192 0.8×	157 1.0×	25	2.7k
Emmanuelle Liaudet‐Coopman France	27	1.3k 0.8×	772 0.8×	470 1.3×	204 0.8×	401 2.5×	38	2.3k
Zhiyong Ding China	20	1.3k 0.8×	450 0.4×	454 1.2×	194 0.8×	254 1.6×	44	2.0k
Hiroshi Okuda Japan	24	1.7k 1.1×	739 0.7×	794 2.2×	213 0.8×	219 1.3×	80	2.9k
Victoria H. Cowling United Kingdom	31	2.3k 1.4×	573 0.6×	488 1.3×	324 1.3×	142 0.9×	58	2.8k

Countries citing papers authored by Joshua J. Gruber

Since Specialization

Citations

This map shows the geographic impact of Joshua J. Gruber's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Joshua J. Gruber with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Joshua J. Gruber more than expected).

Fields of papers citing papers by Joshua J. Gruber

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Joshua J. Gruber. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Joshua J. Gruber. The network helps show where Joshua J. Gruber may publish in the future.

Co-authorship network of co-authors of Joshua J. Gruber

This figure shows the co-authorship network connecting the top 25 collaborators of Joshua J. Gruber. A scholar is included among the top collaborators of Joshua J. Gruber based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Joshua J. Gruber. Joshua J. Gruber is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Nshanian, Michael, Joshua J. Gruber, Benjamin S. Geller, et al.. (2025). Short-chain fatty acid metabolites propionate and butyrate are unique epigenetic regulatory elements linking diet, metabolism and gene expression. Nature Metabolism. 7(1). 196–211. 42 indexed citations breakdown →

Riaz, Fauzia, Joshua J. Gruber, & Melinda L. Telli. (2025). New Treatment Approaches for Triple-Negative Breast Cancer. American Society of Clinical Oncology Educational Book. 45(3). e481154–e481154.

Ariyürek, Yavuz, Susan L. Kloet, Richard P. Davis, et al.. (2024). Genome-wide Cas9-mediated screening of essential non-coding regulatory elements via libraries of paired single-guide RNAs. Nature Biomedical Engineering. 8(7). 890–908. 5 indexed citations

Geller, Benjamin S., D.J. Dixon, Robert Greenhouse, et al.. (2023). Acetyl-Click Screening Platform Identifies Small-Molecule Inhibitors of Histone Acetyltransferase 1 (HAT1). Journal of Medicinal Chemistry. 66(8). 5774–5801. 4 indexed citations

Thakkar, Dipti, Bhushan Dharmadhikari, Siyu Guan, et al.. (2022). Rationally targeted anti-VISTA antibody that blockades the C-C’ loop region can reverse VISTA immune suppression and remodel the immune microenvironment to potently inhibit tumor growth in an Fc independent manner. Journal for ImmunoTherapy of Cancer. 10(2). e003382–e003382. 46 indexed citations

Gruber, Joshua J., Anosheh Afghahi, Kirsten M. Timms, et al.. (2022). A phase II study of talazoparib monotherapy in patients with wild-type BRCA1 and BRCA2 with a mutation in other homologous recombination genes. Nature Cancer. 3(10). 1181–1191. 67 indexed citations

Gruber, Joshua J., Ahmed A. Metwally, Lihua Jiang, et al.. (2021). Chromatin accessibility associates with protein-RNA correlation in human cancer. Nature Communications. 12(1). 5732–5732. 22 indexed citations

Gruber, Joshua J., Ulrike Litzenburger, Yu Rebecca Miao, et al.. (2020). Acetate supplementation restores chromatin accessibility and promotes tumor cell differentiation under hypoxia. Cell Death and Disease. 11(2). 102–102. 47 indexed citations

Chen, Justin, Maria K. Haanpää, Joshua J. Gruber, et al.. (2019). High-Resolution Bisulfite-Sequencing of Peripheral Blood DNA Methylation in Early-Onset and Familial Risk Breast Cancer Patients. Clinical Cancer Research. 25(17). 5301–5314. 11 indexed citations

10.

Telli, Melinda L., Charles C. Chu, Sunil Badve, et al.. (2019). Association of Tumor-Infiltrating Lymphocytes with Homologous Recombination Deficiency and BRCA1/2 Status in Patients with Early Triple-Negative Breast Cancer: A Pooled Analysis. Clinical Cancer Research. 26(11). 2704–2710. 23 indexed citations

11.

Stowers, Ryan S., Anna Shcherbina, Johnny Israeli, et al.. (2019). Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility. Nature Biomedical Engineering. 3(12). 1009–1019. 165 indexed citations

12.

Gruber, Joshua J., Benjamin S. Geller, Andrew M. Lipchik, et al.. (2019). HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding. Molecular Cell. 75(4). 711–724.e5. 58 indexed citations

13.

Gruber, Joshua J., Justin Chen, Benjamin S. Geller, et al.. (2019). Chromatin Remodeling in Response to BRCA2-Crisis. Cell Reports. 28(8). 2182–2193.e6. 13 indexed citations

14.

Liu, Qing, Kevin Van Bortle, Yue Zhang, et al.. (2018). Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid. Scientific Reports. 8(1). 12960–12960. 18 indexed citations

15.

Sailani, M. Reza, Fereshteh Jahanbani, Jafar Nasiri, et al.. (2017). Association of AHSG with alopecia and mental retardation (APMR) syndrome. Human Genetics. 136(3). 287–296. 12 indexed citations

16.

Gruber, Joshua J., Scott H. Olejniczak, Jeongsik Yong, et al.. (2012). Ars2 Promotes Proper Replication-Dependent Histone mRNA 3′ End Formation. Molecular Cell. 45(1). 87–98. 69 indexed citations

17.

Wise, David R., Patrick S. Ward, Jessica E.S. Shay, et al.. (2011). Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability. Proceedings of the National Academy of Sciences. 108(49). 19611–19616. 791 indexed citations breakdown →

18.

Mancuso, Anthony, Thi Bui, Xiangmin Tong, et al.. (2010). Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1α-induced metabolic reprograming. Oncogene. 29(20). 2962–2972. 150 indexed citations

19.

Gruber, Joshua J., Douglas S. Zatechka, Leah R. Sabin, et al.. (2009). Ars2 Links the Nuclear Cap-Binding Complex to RNA Interference and Cell Proliferation. Cell. 138(2). 328–339. 160 indexed citations

20.

Sabin, Leah R., Rui Zhou, Joshua J. Gruber, et al.. (2009). Ars2 Regulates Both miRNA- and siRNA- Dependent Silencing and Suppresses RNA Virus Infection in Drosophila. Cell. 138(2). 340–351. 169 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact