John Manis

13.6k total citations · 2 hit papers
78 papers, 9.3k citations indexed

About

John Manis is a scholar working on Molecular Biology, Immunology and Oncology. According to data from OpenAlex, John Manis has authored 78 papers receiving a total of 9.3k indexed citations (citations by other indexed papers that have themselves been cited), including 42 papers in Molecular Biology, 39 papers in Immunology and 18 papers in Oncology. Recurrent topics in John Manis's work include T-cell and B-cell Immunology (34 papers), DNA Repair Mechanisms (28 papers) and Immune Cell Function and Interaction (26 papers). John Manis is often cited by papers focused on T-cell and B-cell Immunology (34 papers), DNA Repair Mechanisms (28 papers) and Immune Cell Function and Interaction (26 papers). John Manis collaborates with scholars based in United States, Netherlands and France. John Manis's co-authors include Frederick W. Alt, David O. Ferguson, JoAnn Sekiguchi, Yansong Gu, Sonia Franco, Katrin F. Chua, Ming Tian, Chengming Zhu, Karen M. Frank and Jayanta Chaudhuri and has published in prestigious journals such as Nature, New England Journal of Medicine and Cell.

In The Last Decade

John Manis

75 papers receiving 9.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Plasma cell differentiation requires the transcription factor XBP-1

2001 1.0k citations John Manis, Frederick W. Alt et al. profile →
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

2003 925 citations John Manis, Frederick W. Alt et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
John Manis United States	41	6.2k	3.0k	2.3k	1.1k	979	78	9.3k
Noboru Motoyama Japan	36	5.1k 0.8×	1.8k 0.6×	1.8k 0.8×	617 0.6×	1.1k 1.2×	63	7.6k
Jason D. Weber United States	39	6.2k 1.0×	1.6k 0.5×	3.9k 1.7×	623 0.6×	1.4k 1.5×	78	8.9k
Daniel R. Carrasco United States	35	3.8k 0.6×	2.1k 0.7×	2.2k 1.0×	331 0.3×	1.6k 1.7×	53	6.8k
Robert Latek United States	17	5.4k 0.9×	1.2k 0.4×	936 0.4×	698 0.7×	509 0.5×	31	7.6k
Peter M. Finan United Kingdom	26	5.2k 0.8×	1.4k 0.5×	1.2k 0.5×	724 0.7×	1.2k 1.2×	40	7.6k
Steven B. McMahon United States	42	6.5k 1.1×	711 0.2×	2.2k 1.0×	513 0.5×	1.9k 1.9×	77	8.1k
Mila E. McCurrach United States	20	7.3k 1.2×	1.4k 0.5×	3.6k 1.6×	510 0.5×	1.3k 1.3×	21	9.6k
Akihiro Kurimasa Japan	36	4.8k 0.8×	399 0.1×	1.6k 0.7×	597 0.6×	1.2k 1.2×	90	6.3k
Izumi Horikawa United States	40	4.1k 0.7×	554 0.2×	1.3k 0.6×	1.0k 0.9×	1.5k 1.5×	78	6.7k
Domenico Delia Italy	43	4.2k 0.7×	950 0.3×	2.5k 1.1×	379 0.4×	1.2k 1.2×	125	6.9k

Countries citing papers authored by John Manis

Since Specialization

Citations

This map shows the geographic impact of John Manis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John Manis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John Manis more than expected).

Fields of papers citing papers by John Manis

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John Manis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John Manis. The network helps show where John Manis may publish in the future.

Co-authorship network of co-authors of John Manis

This figure shows the co-authorship network connecting the top 25 collaborators of John Manis. A scholar is included among the top collaborators of John Manis based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John Manis. John Manis is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Tanhehco, Yvette C., Suzanne R. Thibodeaux, Patricia A. Shi, et al.. (2025). Challenges and limitations of mobilization and stem cell collection for gene therapy of sickle cell disease. Blood Advances. 9(24). 6524–6533.

Jajosky, Ryan Philip, Kashyap Patel, Patricia E. Zerra, et al.. (2023). Antibody-mediated antigen loss switches augmented immunity to antibody-mediated immunosuppression. Blood. 142(12). 1082–1098. 17 indexed citations

Luo, Sai, Changbin Jing, Adam Yongxin Ye, et al.. (2022). Humanized V(D)J-rearranging and TdT-expressing mouse vaccine models with physiological HIV-1 broadly neutralizing antibody precursors. Proceedings of the National Academy of Sciences. 120(1). e2217883120–e2217883120. 11 indexed citations

Zeng, Jing, Esther Mintzer, Pengpeng Liu, et al.. (2022). Therapeutic Gene Editing of HSCs Ex Vivo without in Vitro Culture Avoids Genotoxicity, Simplifies Procedures, and Preserves Efficiency and Stemness. Blood. 140(Supplement 1). 10671–10672. 1 indexed citations

Teng, Yan, Fabien Loison, Aiming Pang, et al.. (2021). Targeting multiple cell death pathways extends the shelf life and preserves the function of human and mouse neutrophils for transfusion. Science Translational Medicine. 13(604). 18 indexed citations

Zeng, Jing, Yuxuan Wu, Chunyan Ren, et al.. (2020). Therapeutic base editing of human hematopoietic stem cells. Nature Medicine. 26(4). 535–541. 205 indexed citations

Meidan, Esra, Hao Li, Wenliang Pan, et al.. (2020). Serine/threonine phosphatase PP2A is essential for optimal B cell function. JCI Insight. 5(5). 14 indexed citations

Bruin, Lisa M. Ott de, Marita Bosticardo, Alessandro Barbieri, et al.. (2018). Hypomorphic Rag1 mutations alter the preimmune repertoire at early stages of lymphoid development. Blood. 132(3). 281–292. 25 indexed citations

Esrick, Erica B., John Manis, Heather Daley, et al.. (2018). Successful hematopoietic stem cell mobilization and apheresis collection using plerixafor alone in sickle cell patients. Blood Advances. 2(19). 2505–2512. 59 indexed citations

10.

Mooster, Jana L., Séverine Le Bras, Michel J. Massaad, et al.. (2015). Defective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in IκBα. The Journal of Experimental Medicine. 212(2). 185–202. 15 indexed citations

11.

Felgentreff, Kerstin, Likun Du, Katja G. Weinacht, et al.. (2014). Differential role of nonhomologous end joining factors in the generation, DNA damage response, and myeloid differentiation of human induced pluripotent stem cells. Proceedings of the National Academy of Sciences. 111(24). 8889–8894. 34 indexed citations

12.

Wesemann, Duane R., Jennifer M. Magee, Cristian Boboilă, et al.. (2011). Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination. The Journal of Experimental Medicine. 208(13). 2733–2746. 84 indexed citations

13.

Green, Michael R., Stefano Monti, Riccardo Dalla‐Favera, et al.. (2011). Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program. Proceedings of the National Academy of Sciences. 108(7). 2873–2878. 42 indexed citations

14.

Boboilă, Cristian, Catherine T. Yan, Duane R. Wesemann, et al.. (2010). Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4. The Journal of Cell Biology. 188(4). i7–i7. 4 indexed citations

15.

Perlot, Thomas, Inka Pawlitzky, John Manis, et al.. (2010). Analysis of Mice Lacking DNaseI Hypersensitive Sites at the 5′ End of the IgH Locus. PLoS ONE. 5(11). e13992–e13992. 10 indexed citations

16.

Wang, Jing, Frederick W. Alt, Monica Gostissa, et al.. (2008). Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching. The Journal of Experimental Medicine. 205(13). 3079–3090. 58 indexed citations

17.

Franco, Sonia, Monica Gostissa, Shan Zha, et al.. (2006). H2AX Prevents DNA Breaks from Progressing to Chromosome Breaks and Translocations. Molecular Cell. 21(2). 201–214. 224 indexed citations

18.

Bassing, Craig H., Heikyung Suh, David O. Ferguson, et al.. (2003). Histone H2AX. Cell. 114(3). 359–370. 397 indexed citations

19.

Manis, John & Frederick W. Alt. (2003). Novel antibody switching defects in human patients. Journal of Clinical Investigation. 112(1). 19–22. 4 indexed citations

20.

Manis, John, et al.. (1970). Iron transport defect in the intestine of the mouse with sex-linked anemia. Abstr.. The Mouseion at the JAXlibrary (Jackson Laboratory).

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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