John Isaac

13.9k total citations · 4 hit papers
134 papers, 10.7k citations indexed

About

John Isaac is a scholar working on Cellular and Molecular Neuroscience, Cognitive Neuroscience and Molecular Biology. According to data from OpenAlex, John Isaac has authored 134 papers receiving a total of 10.7k indexed citations (citations by other indexed papers that have themselves been cited), including 88 papers in Cellular and Molecular Neuroscience, 51 papers in Cognitive Neuroscience and 42 papers in Molecular Biology. Recurrent topics in John Isaac's work include Neuroscience and Neuropharmacology Research (84 papers), Neural dynamics and brain function (32 papers) and Photoreceptor and optogenetics research (25 papers). John Isaac is often cited by papers focused on Neuroscience and Neuropharmacology Research (84 papers), Neural dynamics and brain function (32 papers) and Photoreceptor and optogenetics research (25 papers). John Isaac collaborates with scholars based in United Kingdom, United States and Singapore. John Isaac's co-authors include Graham L. Collingridge, Robert C. Malenka, Roger A. Nicoll, Michael C. Ashby, Yu Tian Wang, Chris J. McBain, Zuner A. Bortolotto, Roger A. Nicoll, Katherine W. Roche and Tim A. Benke and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

John Isaac

132 papers receiving 10.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Evidence for silent synapses: Implications for the expression of LTP

1995 1.0k citations John Isaac et al. Neuron profile →
Receptor trafficking and synaptic plasticity

2004 819 citations Graham L. Collingridge, John Isaac et al. profile →
The Role of the GluR2 Subunit in AMPA Receptor Function and Synaptic Plasticity

2007 634 citations John Isaac et al. Neuron profile →
LTP Inhibits LTD in the Hippocampus via Regulation of GSK3β

2007 593 citations John Isaac, Zuner A. Bortolotto et al. Neuron profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
John Isaac United Kingdom	49	8.2k	5.0k	3.7k	1.2k	915	134	10.7k
Ceri H. Davies United Kingdom	45	5.7k 0.7×	3.4k 0.7×	2.9k 0.8×	981 0.8×	1.0k 1.1×	102	8.0k
Thomas van Groen United States	52	3.5k 0.4×	2.2k 0.4×	2.9k 0.8×	1.1k 0.9×	2.5k 2.8×	121	8.3k
Masayuki Masu Japan	34	8.5k 1.0×	7.0k 1.4×	961 0.3×	937 0.8×	832 0.9×	67	11.2k
Hilmar Bading Germany	52	8.2k 1.0×	8.1k 1.6×	1.4k 0.4×	1.6k 1.3×	1.8k 2.0×	134	13.9k
Giles E. Hardingham United Kingdom	55	6.6k 0.8×	7.2k 1.4×	1.1k 0.3×	2.0k 1.7×	1.8k 1.9×	133	12.5k
Ken D. McCarthy United States	56	8.6k 1.0×	6.0k 1.2×	1.6k 0.4×	4.7k 3.9×	1.8k 2.0×	99	14.1k
Farrukh A. Chaudhry Norway	38	4.9k 0.6×	3.1k 0.6×	948 0.3×	743 0.6×	1.0k 1.1×	73	7.4k
Thomas Deller Germany	59	5.9k 0.7×	4.0k 0.8×	1.5k 0.4×	2.5k 2.0×	2.5k 2.8×	228	11.0k
Katherine W. Roche United States	53	7.1k 0.9×	5.8k 1.2×	1.5k 0.4×	862 0.7×	900 1.0×	100	9.3k
Karl Obrietan United States	51	4.4k 0.5×	4.0k 0.8×	1.9k 0.5×	796 0.7×	1.4k 1.6×	105	9.9k

Countries citing papers authored by John Isaac

Since Specialization

Citations

This map shows the geographic impact of John Isaac's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John Isaac with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John Isaac more than expected).

Fields of papers citing papers by John Isaac

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John Isaac. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John Isaac. The network helps show where John Isaac may publish in the future.

Co-authorship network of co-authors of John Isaac

This figure shows the co-authorship network connecting the top 25 collaborators of John Isaac. A scholar is included among the top collaborators of John Isaac based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John Isaac. John Isaac is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Wilson, M., Keith Roberts, Robert P. Sutcliffe, et al.. (2021). Influence of middle hepatic vein resection during right or left hepatectomy on post hepatectomy outcomes. HPB. 23. S801–S801.

Kamarajah, Sivesh K., Francesco Giovinazzo, Keith Roberts, et al.. (2020). The role of down staging treatment in the management of locally advanced intrahepatic cholangiocarcinoma: Review of literature and pooled analysis. Annals of Hepato-Biliary-Pancreatic Surgery. 24(1). 6–6. 13 indexed citations

Booker, Sam A., Owen Dando, Adam D. Jackson, et al.. (2019). Altered dendritic spine function and integration in a mouse model of fragile X syndrome. Nature Communications. 10(1). 4813–4813. 45 indexed citations

Brown, Sarah M., et al.. (2014). Experience-Dependent, Layer-Specific Development of Divergent Thalamocortical Connectivity. Cerebral Cortex. 25(8). 2255–2266. 22 indexed citations

Perera, M. Thamara P. R., Keith Roberts, Glenn Kunnath Bonney, et al.. (2014). Outcomes After Liver Transplantation of Patients With Indo-Asian Ethnicity. Transplantation. 99(4). 860–866. 1 indexed citations

Roberts, Keith, Robert P. Sutcliffe, John Isaac, et al.. (2012). Endoscopic ultrasound assessment of lesions of the ampulla of Vater is of particular value in low‐grade dysplasia. HPB. 15(1). 18–23. 8 indexed citations

Battula, Narendra, Dimitrios Tsapralis, Arjun Takhar, et al.. (2012). Aetio-pathogenesis and the management of spontaneous liver bleeding in the West: a 16-year single-centre experience. HPB. 14(6). 382–389. 26 indexed citations

Chakrabarti, Lina, Tyler K. Best, Nathan Cramer, et al.. (2010). Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome. Nature Neuroscience. 13(8). 927–934. 170 indexed citations

Nasu‐Nishimura, Yukiko, Howard Jaffe, John Isaac, & Katherine W. Roche. (2009). Differential Regulation of Kainate Receptor Trafficking by Phosphorylation of Distinct Sites on GluR6. Journal of Biological Chemistry. 285(4). 2847–2856. 42 indexed citations

10.

Lauri, Sari E., Aino Vesikansa, Mikael Segerstråle, et al.. (2006). Functional Maturation of CA1 Synapses Involves Activity-Dependent Loss of Tonic Kainate Receptor-Mediated Inhibition of Glutamate Release. Neuron. 50(3). 415–429. 113 indexed citations

11.

Jo, Jihoon, et al.. (2006). Long-Term Depression of Kainate Receptor-Mediated Synaptic Transmission. Neuron. 49(1). 95–106. 53 indexed citations

12.

Maingret, François, Sari E. Lauri, Tomi Taira, & John Isaac. (2005). Profound regulation of neonatal CA1 rat hippocampal GABAergic transmission by functionally distinct kainate receptor populations. The Journal of Physiology. 567(1). 131–142. 46 indexed citations

13.

Palmer, Claire L., Viktor I. Korolchuk, Stephen A. Burbidge, et al.. (2005). Hippocalcin Functions as a Calcium Sensor in Hippocampal LTD. Neuron. 47(4). 487–494. 107 indexed citations

14.

Hirbec, Hélène, Sari E. Lauri, Steven P. Braithwaite, et al.. (2003). Rapid and Differential Regulation of AMPA and Kainate Receptors at Hippocampal Mossy Fibre Synapses by PICK1 and GRIP. Neuron. 37(4). 625–638. 178 indexed citations

15.

Lauri, Sari E., Zuner A. Bortolotto, Robert Nisticò, et al.. (2003). A Role for Ca2+ Stores in Kainate Receptor-Dependent Synaptic Facilitation and LTP at Mossy Fiber Synapses in the Hippocampus. Neuron. 39(2). 327–341. 159 indexed citations

16.

Bortolotto, Zuner A., Sari E. Lauri, John Isaac, & Graham L. Collingridge. (2003). Kainate receptors and the induction of mossy fibre long-term potentiation. Philosophical Transactions of the Royal Society B Biological Sciences. 358(1432). 657–666. 43 indexed citations

17.

Lauri, Sari E., Zuner A. Bortolotto, David Bleakman, et al.. (2001). A Critical Role of a Facilitatory Presynaptic Kainate Receptor in Mossy Fiber LTP. Neuron. 32(4). 697–709. 162 indexed citations

18.

Isaac, John, et al.. (1999). Developmental and activity- dependent regulation of kainate receptors at thalamocortical synapses. Nature. 400(6744). 569–573. 189 indexed citations

19.

Crabtree, John W., Graham L. Collingridge, & John Isaac. (1998). A new intrathalamic pathway linking modality-related nuclei in the dorsal thalamus. Nature Neuroscience. 1(5). 389–394. 84 indexed citations

20.

Adam, René, et al.. (1991). High levels of glycogen in the donor liver improve survival after liver transplantation in rats.. PubMed. 23(5). 2465–6. 14 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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