John Groffen

18.5k total citations · 5 hit papers
195 papers, 13.0k citations indexed

About

John Groffen is a scholar working on Hematology, Molecular Biology and Genetics. According to data from OpenAlex, John Groffen has authored 195 papers receiving a total of 13.0k indexed citations (citations by other indexed papers that have themselves been cited), including 97 papers in Hematology, 78 papers in Molecular Biology and 65 papers in Genetics. Recurrent topics in John Groffen's work include Chronic Myeloid Leukemia Treatments (94 papers), Chronic Lymphocytic Leukemia Research (59 papers) and Acute Lymphoblastic Leukemia research (40 papers). John Groffen is often cited by papers focused on Chronic Myeloid Leukemia Treatments (94 papers), Chronic Lymphocytic Leukemia Research (59 papers) and Acute Lymphoblastic Leukemia research (40 papers). John Groffen collaborates with scholars based in United States, Netherlands and United Kingdom. John Groffen's co-authors include Nora Heisterkamp, John Stephenson, Gerard C. Grosveld, Annelies de Klein, Vesa Kaartinen, Claus R. Bartram, D. Bootsma, Jan Willem Voncken, Leena Haataja and Charles F. Shuler and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

John Groffen

194 papers receiving 12.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

1982 1.1k citations Annelies de Klein, Gerard C. Grosveld et al. profile →
Abnormal lung development and cleft palate in mice lacking TGF–β3 indicates defects of epithelial–mesenchymal interaction

1995 877 citations Vesa Kaartinen, David Warburton et al. profile →
Localization of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia

1983 687 citations Nora Heisterkamp, John Stephenson et al. profile →
Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia

1983 551 citations Annelies de Klein, D. Bootsma et al. profile →
Acute leukaemia in bcr/abl transgenic mice

1990 545 citations Nora Heisterkamp, Paul K. Pattengale et al. profile →

Peers

Countries citing papers authored by John Groffen

Since Specialization

Citations

This map shows the geographic impact of John Groffen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John Groffen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John Groffen more than expected).

Fields of papers citing papers by John Groffen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John Groffen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John Groffen. The network helps show where John Groffen may publish in the future.

Co-authorship network of co-authors of John Groffen

This figure shows the co-authorship network connecting the top 25 collaborators of John Groffen. A scholar is included among the top collaborators of John Groffen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John Groffen. John Groffen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Treatment of human pre-B acute lymphoblastic leukemia with the Aurora kinase inhibitor PHA-739358 (Danusertib) 2012 ·Molecular Cancer ·Fei Fei, (unknown), Sabine Schmidhuber, Jürgen Moll, John Groffen, Nora Heisterkamp	20
2	A Functional Receptor for B-Cell–Activating Factor Is Expressed on Human Acute Lymphoblastic Leukemias 2010 ·Cancer Research ·Reshmi Parameswaran, Markus Müschen, Yong‐Mi Kim, John Groffen, Nora Heisterkamp	46
3	The Fer tyrosine kinase regulates interactions of Rho GDP-Dissociation Inhibitor α with the small GTPase Rac 2010 ·BMC Biochemistry ·Fei Fei, (unknown), Leena Haataja, Paulo De Sepulveda, John Groffen, Nora Heisterkamp	13
4	Transglutaminase 2 Regulates the GTPase-activating Activity of Bcr 2009 ·Journal of Biological Chemistry ·Sun-Ju Yi, John Groffen, Nora Heisterkamp	11
5	The human gamma-glutamyltransferase gene family 2008 ·Human Genetics ·Nora Heisterkamp, John Groffen, David Warburton, Tam P. Sneddon	115
6	Nilotinib treatment in mouse models of P190 Bcr/Abl lymphoblastic leukemia 2007 ·Molecular Cancer ·(unknown), Niklas Feldhahn, Bin Zhang, Daniel Trageser, Markus Müschen, (unknown), John Groffen, Nora Heisterkamp	33
7	Progressive pulmonary fibrosis is mediated by TGF-β isoform 1 but not TGF-β3 2007 ·The International Journal of Biochemistry & Cell Biology ·Kjetil Ask, Philippe Bonniaud, Katja Maaß, Oliver Eickelberg, Peter J. Margetts, David Warburton, John Groffen, Jack Gauldie, Martin Kolb	146
8	BCR/ABL P190 transgenic mice develop leukemia in the absence of Crkl 2002 ·Oncogene ·Bianca Hemmeryckx, Anja Reichert, (unknown), Vesa Kaartinen, Ron de Jong, Paul K. Pattengale, John Groffen, Nora Heisterkamp	23
9	Crkl enhances leukemogenesis in BCR/ABL P190 transgenic mice. 2001 ·PubMed ·Bianca Hemmeryckx, (unknown), A. Reichert, Vesa Kaartinen, Ron de Jong, P K Pattengale, Ignacio González-Gómez, John Groffen, Nora Heisterkamp	38
10	Philadelphia-negative chronic myelogenous leukemia in a patient with a unique complex translocation: 46,XY,t(9;12;15)(q34;q12;q21) 1998 ·Leukemia Research ·Alan Shanske, Hans Grünwald, Perry Cook, Nora Heisterkamp, John Groffen	1
11	C3G is tyrosine-phosphorylated after integrin-mediated cell adhesion in normal but not in Bcr/Abl expressing cells 1998 ·Oncogene ·Ron de Jong, (unknown), Nora Heisterkamp, John Groffen	29
12	Characterization of RAC3, a Novel Member of the Rho Family 1997 ·Journal of Biological Chemistry ·Leena Haataja, John Groffen, Nora Heisterkamp	202
13	Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site 1997 ·Oncogene ·Ron de Jong, Johanna ten Hoeve, Nora Heisterkamp, John Groffen	75
14	Transfection with γ-glutamyl transpeptidase enhances recovery from glutathione depletion using extracellular glutathione 1992 ·Toxicology and Applied Pharmacology ·Ewa Rajpert‐De Meyts, Ming Shi, (unknown), Timothy W. Robison, John Groffen, Nora Heisterkamp, Henry Jay Forman	54
15	Philadelphia chromosome translocation. 1989 ·PubMed ·John Groffen, Nora Heisterkamp	11
16	Molecular characterization of variant translocations in chronic myelogenous leukemia. 1989 ·PubMed ·Ram S. Verma, Michael J. Macera, Peter Benn, John Groffen	5
17	The FER Gene Is Evolutionarily Conserved and Encodes a Widely Expressed Member of the FPS/FES Protein-Tyrosine Kinase Family 1989 ·Molecular and Cellular Biology ·Tony Pawson, K Letwin, (unknown), Qian‐Lin Hao, Nora Heisterkamp, John Groffen	5
18	Nucleotide sequence of both reciprocal translocation junction regions in a patient with Ph positive acute lymphoblastic leukaemia, with a breakpoint within the first intron of theBCRgene 1989 ·Nucleic Acids Research ·(unknown), Mahmud K. K. Shivji, Patrick B. Allen, Nora Heisterkamp, John Groffen, Leanne M. Wiedemann	122
19	ABR, an active BCR-related gene 1989 ·Nucleic Acids Research ·Nora Heisterkamp, Christine M. Morris, John Groffen	33
20	c-sis is translocated from chromosome 22 to chromosome 9 in chronic myelocytic leukemia. 1983 ·The Journal of Experimental Medicine ·John Groffen, Nora Heisterkamp, John Stephenson, (unknown), Annelies de Klein, Gerard C. Grosveld, D. Bootsma	83

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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