John E. Leet

2.1k citations

55 papers · 1.7k indexed · h-index 25

Pharmacology top 1%
- Microbial Natural Products and Biosynthesis 13
Biotechnology top 2%
- Marine Sponges and Natural Products 3
Microbiology top 5%
Organic Chemistry top 2%
- Chemical synthesis and alkaloids 4
Toxicology top 2%
- Bioactive Compounds and Antitumor Agents 3
Spectroscopy
- Analytical Chemistry and Chromatography 6
Molecular Biology
- Cancer therapeutics and mechanisms 5
Hepatology
- Hepatitis C virus research 4
Biochemistry
- Traditional and Medicinal Uses of Annonaceae 4

Co-authors: Stella Huang Daniel R. Schroeder James A. Matson Steven E. Klohr Kin S. Lam Jerzy Golik Kimberly L. Colson Terrence W. Doyle
Cited by: Pharmacology Biotechnology Microbiology
Journals: Journal of Natural Products (8 papers)The Journal of Antibiotics (7 papers)Journal of the American Chemical Society (5 papers)
Partner nations: United States Germany Poland

In The Last Decade

John E. Leet

55 papers receiving 1.6k citations

Peers

Countries citing papers authored by John E. Leet

Since Specialization

Citations

This map shows the geographic impact of John E. Leet's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John E. Leet with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John E. Leet more than expected).

Fields of papers citing papers by John E. Leet

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John E. Leet. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John E. Leet. The network helps show where John E. Leet may publish in the future.

Co-authorship network

The 25 scholars most cited alongside John E. Leet, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John E. Leet Line = papers co-authored together John E. Leet links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Phosphocholine Conjugation: An Unexpected In Vivo Conjugation Pathway Associated with Hepatitis C NS5B Inhibitors Featuring A Bicyclo[1.1.1]Pentane Drug Metabolism and Disposition ·Xianlu Zhuo,H. Riethmüller,Yuefeng Wang,John E. Leet,Dieter M. Drexler,Kap‐Sun Yeung,Xuan Huang,Kyle J. Eastman,桂香李,Kathy Mosure,Matthew G. Soars,John F. Kadow,Benjamin M. Johnson	2016	4
2	HPLC Biogram Analysis: A Powerful Tool Used for Hit Confirmation in Early Drug Discovery SLAS DISCOVERY ·John E. Leet,Thomas Jonasson,Iqra Nisar,Gregory A. Nemeth,Harold N. Weller	2015	8
3	Labware Additives Identified to Be Selective Monoamine Oxidase-B Inhibitors SLAS DISCOVERY ·Jeremy Stewart,Dieter M. Drexler,John E. Leet,Musie T Tsehaye,John J. Herbst	2014	6
4	High-Throughput Screening and Rapid Inhibitor Triage Using an Infectious Chimeric Hepatitis C Virus PLoS ONE ·Michael Wichroski,Jie Fang,Betsy J. Eggers,Ronald E. Rose,Charles E. Mazzucco,Kevin A. Pokornowski,Carl J. Baldick,Jih-Yiing Lin,Iqra Nisar,Lauren E. Barber,John E. Leet,Brett R. Beno,Samuel W. Gerritz,Juana Castro Muñoz,Mark I. Cockett,Daniel J. Tenney	2012	8
5	Studies to Further Investigate the Inhibition of Human Liver Microsomal CYP2C8 by the Acyl-β-Glucuronide of Gemfibrozil Drug Metabolism and Disposition ·S. M. Jenkins,Tatyana Zvyaga,Catia Picolo Vieira Devechi,Ibolya Bagi,Andrew J. Wagner,Richard C. Burrell,Wasmaa S. suleman,John E. Leet,Oliver Schöffski,A. David Rodrigues	2011	25
6	Discovery of Potent Hepatitis C Virus NS5A Inhibitors with Dimeric Structures Antimicrobial Agents and Chemotherapy ·Julie A. Lemm,John E. Leet,Donald R. O’Boyle,J. Romine,Xiaohua Huang,Daniel R. Schroeder,Jeffrey R. Alberts,Joseph L. Cantone,Jin-Hua Sun,Peter T. Nower,Scott Martin,Michael H. Serrano‐Wu,Nicholas A. Meanwell,Lawrence B. Snyder,Min Gao	2011	38
7	Extraction, Identification, and Functional Characterization of a Bioactive Substance From Automated Compound-Handling Plastic Tips SLAS DISCOVERY ·John B. Watson,Jun-shuan Wu,John E. Leet,Michael J. Ford,Dieter M. Drexler,Thomas Jonasson,John J. Herbst,Rim CHAKRAOUI,Martyn Banks	2009	32
8	Best Practices in Compound Management for Preserving Compound Integrity and Accurately Providing Samples for Assays SLAS DISCOVERY ·Vicente Basualto-Luna,Rim CHAKRAOUI,David Stock,John E. Leet,Xinyu Dou,Charles Tshimanga-Kashama,Mark McGovern,Lynda Cook,John B. Watson,Normand J. Cloutier,Daiki Kayano,John G. Houston,Martyn Banks	2009	21
9	Comparative Biotransformation of Pyrazinone-Containing Corticotropin-Releasing Factor Receptor-1 Antagonists: Minimizing the Reactive Metabolite Formation Drug Metabolism and Disposition ·Xiaoliang Zhuo,Richard A. Hartz,Joanne J. Bronson,Harvey Wong,Vijay T. Ahuja,Vivekananda M. Vrudhula,John E. Leet,Stella Huang,John E. Macor,Yue‐Zhong Shu	2009	16
10	N-Demethylation of nocathiacin I via photo-oxidation Bioorganic & Medicinal Chemistry Letters ·Wenying Li,Stella Huang,Xiaohong Liu,John E. Leet,Joseph L. Cantone,Kin S. Lam	2008	6
11	Adverse effects of gabapentin and lack of anti-allodynic efficacy of amitriptyline in the streptozotocin model of painful diabetic neuropathy. Experimental and Clinical Psychopharmacology ·Mark D. Lindner,Clotilde Bourin,Ping Chen,John F. McElroy,John E. Leet,John B. Hogan,David Stock,K Tubaki	2006	14
12	Donepezil primarily attenuates scopolamine-induced deficits in psychomotor function, with moderate effects on simple conditioning and attention, and small effects on working memory and spatial mapping Psychopharmacology ·Mark D. Lindner,John B. Hogan,Donald B. Hodges,Zezhou Sui,Ping Chen,Jason A. Corsa,John E. Leet,Kevin W. Gillman,Gregory M. Rose,Kelli Jones,Valentin K. Gribkoff	2006	54
13	Nocathiacins, New Thiazolyl Peptide Antibiotics from Nocardia sp. II. Isolation, Characterization, and Structure Determination. The Journal of Antibiotics ·John E. Leet,Wenying Li,HELEN A. AX,James A. Matson,Stella Huang,Ron Huang,Joseph L. Cantone,Dieter M. Drexler,R. A. Dalterio,Kin S. Lam	2003	75
14	BMS-182123, a Fungal Metabolite that Inhibits the Production of TNF-.ALPHA. by Macrophages and Monocytes. The Journal of Antibiotics ·Glenn A. Warr,H. A. Stuart,Ann W. Walsh,Birdyne Yanuar Melani,DOLORES M. PIRNIK,John E. Leet,Pin-Fang Lin,Jhonathan Narváez Sánchez,Susan Febrina,Salvatore Forenza,Junius M. Clark,Kin S. Lam	1996	44
15	Himastatin, a New Antitumor Antibiotic from Streptomyces hygroscopicus. III. Structural Elucidation. The Journal of Antibiotics ·John E. Leet,Daniel R. Schroeder,Jerzy Golik,James A. Matson,Terrence W. Doyle,Kin S. Lam,Susan E. Hill,Mike S. Lee,N. Tanriöver N. Gazio lu,Bala Krishnan	1996	47
16	Rakicidins, New Cytotoxic Lipopeptides from Micromonospora sp. Fermentation, Isolation and Characterization. The Journal of Antibiotics ·Susan Febrina,Ronald L. Berry,Susan E. Lowe,Kim M. Neddermann,Isia Bursuker,Stella Huang,Steven E. Klohr,John E. Leet	1995	83
17	Selective proteolytic activity of the antitumor agent kedarcidin. Proceedings of the National Academy of Sciences ·Nada Zein,Anna Maria Casazza,Terrence W. Doyle,John E. Leet,Daniel R. Schroeder,Stephan Mühlebach,Steven G. Nadler	1993	34
18	Antineoplastic agents. 219. Isolation and structure of the cell growth inhibitory constituents from the western Pacific marine sponge Axinella sp Journal of Medicinal Chemistry ·George R. Pettit,Cherry L. Herald,Michael R. Boyd,John E. Leet,Claude Dufresne,Dennis L. Doubek,Jean M. Schmidt,Ronald L. Cerny,A Schmitt,Shin-Ichi Masunari	1991	146
19	Himastatin, a new antitumor antibiotic from Streptomyces hygroscopicus. II. Isolation and characterization. The Journal of Antibiotics ·John E. Leet,Daniel R. Schroeder,Bala Krishnan,James A. Matson	1990	42
20	Chiloenamine and chiloenine: two unusual isoquinoline derived alkaloids. A new insight into the catabolism of aporphines Journal of the Chemical Society Chemical Communications ·Maurice Shamma,VC Worthington,Alan J. Freyer,John E. Leet,Alejandro Urzúa,Víctor Fajardo	1983	4

About John E. Leet

John E. Leet is a scholar working on Microbiology, Horticulture, Pharmacology, Toxicology and Organic Chemistry, having authored 55 papers that have together received 1.7k indexed citations. Recurring topics across this work include Microbial Natural Products and Biosynthesis (13 papers), Analytical Chemistry and Chromatography (6 papers), Cancer therapeutics and mechanisms (5 papers), Hepatitis C virus research (4 papers), Chemical synthesis and alkaloids (4 papers), Traditional and Medicinal Uses of Annonaceae (4 papers), Bioactive Compounds and Antitumor Agents (3 papers) and Marine Sponges and Natural Products (3 papers). The work is most often cited by research in Pharmacology (624 citations), Biotechnology (293 citations), Microbiology (23 citations), Organic Chemistry (760 citations) and Toxicology (82 citations). John E. Leet has collaborated with scholars based in United States, Germany and Poland. Frequent co-authors include Stella Huang, Daniel R. Schroeder, James A. Matson, Steven E. Klohr, Kin S. Lam, Jerzy Golik, Kimberly L. Colson, Terrence W. Doyle, Sandra J. Hofstead and Cherry L. Herald. Their work appears in journals such as Journal of Natural Products, The Journal of Antibiotics, Journal of the American Chemical Society, SLAS DISCOVERY and Drug Metabolism and Disposition.

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