John Aach

27.2k total citations · 6 hit papers
38 papers, 15.5k citations indexed

About

John Aach is a scholar working on Molecular Biology, Genetics and Biomedical Engineering. According to data from OpenAlex, John Aach has authored 38 papers receiving a total of 15.5k indexed citations (citations by other indexed papers that have themselves been cited), including 34 papers in Molecular Biology, 10 papers in Genetics and 2 papers in Biomedical Engineering. Recurrent topics in John Aach's work include CRISPR and Genetic Engineering (17 papers), RNA and protein synthesis mechanisms (8 papers) and Gene expression and cancer classification (8 papers). John Aach is often cited by papers focused on CRISPR and Genetic Engineering (17 papers), RNA and protein synthesis mechanisms (8 papers) and Gene expression and cancer classification (8 papers). John Aach collaborates with scholars based in United States, France and United Kingdom. John Aach's co-authors include George M. Church, Prashant Mali, James J. DiCarlo, Julie E. Norville, Kevin M. Esvelt, Marc Güell, Luhan Yang, Xavier Rios, Luhan Yang and Sriram Kosuri and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

John Aach

38 papers receiving 15.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

RNA-Guided Human Genome Engineering via Cas9

2013 7.0k citations Prashant Mali, Luhan Yang et al. Science profile →
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

2013 1.4k citations Prashant Mali, John Aach et al. Nature Biotechnology profile →
Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

2013 1.2k citations James J. DiCarlo, Julie E. Norville et al. profile →
Highly efficient Cas9-mediated transcriptional programming

2015 1.2k citations Jonathan Scheiman, Eswar Prasad R. Iyer et al. Nature Methods profile →
Highly Multiplexed Subcellular RNA Sequencing in Situ

2014 693 citations Je Hyuk Lee, Evan R Daugharthy et al. Science profile →
Genome-wide inactivation of porcine endogenous retroviruses (PERVs)

2015 410 citations Luhan Yang, Marc Güell et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
John Aach United States	32	14.0k	2.9k	1.4k	963	855	38	15.5k
Luke A. Gilbert United States	38	16.2k 1.2×	2.8k 1.0×	1.3k 0.9×	1.2k 1.2×	941 1.1×	68	18.0k
Xuebing Wu United States	25	18.8k 1.3×	4.4k 1.5×	2.1k 1.5×	1.3k 1.3×	1.4k 1.6×	35	20.7k
Lei S. Qi United States	55	19.9k 1.4×	3.9k 1.4×	1.8k 1.3×	1.4k 1.4×	1.3k 1.5×	186	22.2k
Le Cong United States	34	17.5k 1.3×	4.1k 1.4×	2.1k 1.5×	1.1k 1.1×	1.3k 1.5×	60	20.7k
Kevin M. Esvelt United States	25	12.3k 0.9×	3.0k 1.0×	1.6k 1.1×	1.1k 1.1×	985 1.2×	50	13.7k
Marc Güell Spain	20	8.8k 0.6×	2.3k 0.8×	981 0.7×	591 0.6×	586 0.7×	37	10.5k
Vineeta Agarwala United States	10	10.0k 0.7×	2.2k 0.8×	896 0.6×	615 0.6×	492 0.6×	18	12.0k
David Scott United States	34	20.7k 1.5×	4.0k 1.4×	2.1k 1.5×	1.3k 1.3×	1.6k 1.9×	53	24.2k
F. Ann Ran United States	19	29.0k 2.1×	6.5k 2.3×	3.0k 2.1×	2.0k 2.1×	2.4k 2.8×	25	32.3k
John G. Doench United States	51	15.7k 1.1×	2.1k 0.7×	1.0k 0.7×	719 0.7×	488 0.6×	145	20.0k

Countries citing papers authored by John Aach

Since Specialization

Citations

This map shows the geographic impact of John Aach's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John Aach with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John Aach more than expected).

Fields of papers citing papers by John Aach

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John Aach. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John Aach. The network helps show where John Aach may publish in the future.

Co-authorship network of co-authors of John Aach

This figure shows the co-authorship network connecting the top 25 collaborators of John Aach. A scholar is included among the top collaborators of John Aach based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John Aach. John Aach is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Kohman, Richie E., Jeantine E. Lunshof, Bruna Paulsen, et al.. (2021). Minibrains: What's in a Name?. American Scientist. 109(4). 208–208. 1 indexed citations

Filsinger, Gabriel, Timothy M. Wannier, Julie Zhang, et al.. (2021). Characterizing the portability of phage-encoded homologous recombination proteins. Nature Chemical Biology. 17(4). 394–402. 40 indexed citations

Aach, John, Jeantine E. Lunshof, Eswar Prasad R. Iyer, & George M. Church. (2017). Addressing the ethical issues raised by synthetic human entities with embryo-like features. eLife. 6. 83 indexed citations

Kuznetsov, Gleb, Daniel B. Goodman, Gabriel Filsinger, et al.. (2017). Optimizing complex phenotypes through model-guided multiplex genome engineering. Genome biology. 18(1). 100–100. 23 indexed citations

Yang, Luhan, Adrian W. Briggs, Wei Leong Chew, et al.. (2016). Engineering and optimising deaminase fusions for genome editing. Nature Communications. 7(1). 13330–13330. 61 indexed citations

Lee, Je Hyuk, Evan R Daugharthy, Jonathan Scheiman, et al.. (2014). Highly Multiplexed Subcellular RNA Sequencing in Situ. Science. 343(6177). 1360–1363. 693 indexed citations breakdown →

Mali, Prashant, Luhan Yang, Kevin M. Esvelt, et al.. (2013). RNA-Guided Human Genome Engineering via Cas9. Science. 339(6121). 823–826. 6968 indexed citations breakdown →

Mali, Prashant, John Aach, P. Benjamin Stranges, et al.. (2013). CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nature Biotechnology. 31(9). 833–838. 1379 indexed citations breakdown →

Mali, Prashant, et al.. (2013). Barcoding cells using cell-surface programmable DNA-binding domains. Nature Methods. 10(5). 403–406. 39 indexed citations

10.

Li, Jin Billy, Erez Y. Levanon, Jung-Ki Yoon, et al.. (2009). Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing. Science. 324(5931). 1210–1213. 434 indexed citations

11.

Li, Jin Billy, Yuan Gao, John Aach, et al.. (2009). Multiplex padlock targeted sequencing reveals human hypermutable CpG variations. Genome Research. 19(9). 1606–1615. 51 indexed citations

12.

Zhang, Kun, Jin Billy Li, Yuan Gao, et al.. (2009). Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human. Nature Methods. 6(8). 613–618. 122 indexed citations

13.

Bakal, Chris, John Aach, George M. Church, & Norbert Perrimon. (2007). Quantitative Morphological Signatures Define Local Signaling Networks Regulating Cell Morphology. Science. 316(5832). 1753–1756. 233 indexed citations

14.

Zhang, Kun, Jun Zhu, Jay Shendure, et al.. (2006). Long-range polony haplotyping of individual human chromosome molecules. Nature Genetics. 38(3). 382–387. 58 indexed citations

15.

Aach, John & George M. Church. (2004). Mathematical models of diffusion-constrained polymerase chain reactions: basis of high-throughput nucleic acid assays and simple self-organizing systems. Journal of Theoretical Biology. 228(1). 31–46. 12 indexed citations

16.

Grad, Yonatan H., John Aach, Gabriel D. Hayes, et al.. (2003). Computational and Experimental Identification of C. elegans microRNAs. Molecular Cell. 11(5). 1253–1263. 238 indexed citations

17.

Dudley, Aimée M., John Aach, Martín Steffen, & George M. Church. (2002). Measuring absolute expression with microarrays with a calibrated reference sample and an extended signal intensity range. Proceedings of the National Academy of Sciences. 99(11). 7554–7559. 190 indexed citations

18.

Steffen, Martín, Allegra A. Petti, John Aach, Patrik D’haeseleer, & George M. Church. (2002). Automated modelling of signal transduction networks. BMC Bioinformatics. 3(1). 34–34. 165 indexed citations

19.

Aach, John, Martha L. Bulyk, George M. Church, et al.. (2001). Computational comparison of two draft sequences of the human genome. Nature. 409(6822). 856–859. 40 indexed citations

20.

Aach, John, Wayne P. Rindone, & George M. Church. (2000). Systematic Management and Analysis of Yeast Gene Expression Data. Genome Research. 10(4). 431–445. 90 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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