John A. Chaddock

1.4k total citations
31 papers, 1.1k citations indexed

About

John A. Chaddock is a scholar working on Neurology, Molecular Biology and Immunology. According to data from OpenAlex, John A. Chaddock has authored 31 papers receiving a total of 1.1k indexed citations (citations by other indexed papers that have themselves been cited), including 21 papers in Neurology, 18 papers in Molecular Biology and 9 papers in Immunology. Recurrent topics in John A. Chaddock's work include Botulinum Toxin and Related Neurological Disorders (20 papers), Biochemical and Structural Characterization (11 papers) and Toxin Mechanisms and Immunotoxins (9 papers). John A. Chaddock is often cited by papers focused on Botulinum Toxin and Related Neurological Disorders (20 papers), Biochemical and Structural Characterization (11 papers) and Toxin Mechanisms and Immunotoxins (9 papers). John A. Chaddock collaborates with scholars based in United Kingdom, United States and France. John A. Chaddock's co-authors include K. Ravi Acharya, R. Turton, Lynne M. Roberts, Keith Foster, Clifford C. Shone, Janet M. Lord, Frances C.G. Alexander, Geoffrey Masuyer, Martin R. Hartley and John R. Purkiss and has published in prestigious journals such as Nucleic Acids Research, Journal of Biological Chemistry and Scientific Reports.

In The Last Decade

John A. Chaddock

31 papers receiving 957 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
John A. Chaddock United Kingdom	18	691	367	329	242	173	31	1.1k
Audrey Fischer United States	16	528 0.8×	356 1.0×	185 0.6×	49 0.2×	8 0.0×	19	751
Dario Besusso Italy	17	55 0.1×	211 0.6×	533 1.6×	312 1.3×	66 0.4×	31	1.0k
Magali Chemali Canada	8	162 0.2×	81 0.2×	447 1.4×	251 1.0×	7 0.0×	9	1.0k
Dustin Dikeman United States	13	512 0.7×	165 0.4×	387 1.2×	97 0.4×	8 0.0×	26	915
Jessica M. Jones United States	21	208 0.3×	99 0.3×	756 2.3×	225 0.9×	5 0.0×	26	1.2k
Stefan Mahrhold Germany	18	1.1k 1.6×	799 2.2×	238 0.7×	53 0.2×	6 0.0×	22	1.3k
Camilla Lööv Sweden	10	134 0.2×	106 0.3×	707 2.1×	121 0.5×	40 0.2×	12	972
Diana Matheoud Canada	9	373 0.5×	148 0.4×	515 1.6×	413 1.7×	7 0.0×	12	1.3k
K Kitamura Japan	13	69 0.1×	74 0.2×	170 0.5×	28 0.1×	89 0.5×	38	657
M H Wong Australia	16	21 0.0×	122 0.3×	387 1.2×	99 0.4×	42 0.2×	22	864

Countries citing papers authored by John A. Chaddock

Since Specialization

Citations

This map shows the geographic impact of John A. Chaddock's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John A. Chaddock with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John A. Chaddock more than expected).

Fields of papers citing papers by John A. Chaddock

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John A. Chaddock. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John A. Chaddock. The network helps show where John A. Chaddock may publish in the future.

Co-authorship network of co-authors of John A. Chaddock

This figure shows the co-authorship network connecting the top 25 collaborators of John A. Chaddock. A scholar is included among the top collaborators of John A. Chaddock based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John A. Chaddock. John A. Chaddock is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Masuyer, Geoffrey, Jonathan Davies, Kevin B. Moore, John A. Chaddock, & K. Ravi Acharya. (2015). Structural analysis of Clostridium botulinum neurotoxin type D as a platform for the development of targeted secretion inhibitors. Scientific Reports. 5(1). 13397–13397. 13 indexed citations

Chaddock, John A.. (2012). Transforming the Domain Structure of Botulinum Neurotoxins into Novel Therapeutics. Current topics in microbiology and immunology. 364. 287–306. 7 indexed citations

Chaddock, John A. & K. Ravi Acharya. (2011). Engineering toxins for 21st century therapies. FEBS Journal. 278(6). 899–904. 5 indexed citations

Masuyer, Geoffrey, et al.. (2011). Structures of engineered Clostridium botulinum neurotoxin derivatives. Acta Crystallographica Section F Structural Biology and Crystallization Communications. 67(12). 1466–1472. 8 indexed citations

Masuyer, Geoffrey, Ian Birch‐Machin, Matthew Beard, et al.. (2011). Engineering botulinum neurotoxin domains for activation by toxin light chain. FEBS Journal. 279(3). 515–523. 11 indexed citations

Masuyer, Geoffrey, et al.. (2010). Structure and activity of a functional derivative of Clostridium botulinum neurotoxin B. Journal of Structural Biology. 174(1). 52–57. 15 indexed citations

Masuyer, Geoffrey, et al.. (2009). Crystal structure of a catalytically active, non-toxic endopeptidase derivative of Clostridium botulinum toxin A. Biochemical and Biophysical Research Communications. 381(1). 50–53. 18 indexed citations

He, Yan, Chadwick L. Elias, Ya‐Chi Huang, et al.. (2008). Botulinum Neurotoxin A and Neurotoxin E Cleavage Products of Synaptosome-Associated Protein of 25 kd Exhibit Distinct Actions on Pancreatic Islet β-Cell Kv2.1 Channel Gating. Pancreas. 36(1). 10–17. 12 indexed citations

Chaddock, John A., et al.. (2006). Clostridial neurotoxins: structure-function led design of new therapeutics. Cellular and Molecular Life Sciences. 63(5). 540–551. 22 indexed citations

10.

Sutton, J. Mark, Anthony Scott-Tucker, Susan O’Brien, et al.. (2005). Preparation of specifically activatable endopeptidase derivatives of Clostridium botulinum toxins type A, B, and C and their applications. Protein Expression and Purification. 40(1). 31–41. 16 indexed citations

11.

Chaddock, John A., John R. Purkiss, Frances C.G. Alexander, et al.. (2004). Retargeted clostridial endopeptidases: Inhibition of nociceptive neurotransmitter release in vitro, and antinociceptive activity in in vivo models of pain. Movement Disorders. 19(S8). S42–S47. 50 indexed citations

12.

Hall, Yper, et al.. (2004). Novel application of an in vitro technique to the detection and quantification of botulinum neurotoxin antibodies. Journal of Immunological Methods. 288(1-2). 55–60. 20 indexed citations

13.

Alexander, Frances C.G., et al.. (2003). Isolation of the gene and large-scale expression and purification of recombinant Erythrina cristagalli lectin. Protein Expression and Purification. 30(2). 283–292. 13 indexed citations

14.

Duggan, Michael, John A. Chaddock, John R. Purkiss, et al.. (2002). Inhibition of Release of Neurotransmitters from Rat Dorsal Root Ganglia by a Novel Conjugate of a Clostridium botulinumToxin A Endopeptidase Fragment and Erythrina cristagalliLectin. Journal of Biological Chemistry. 277(38). 34846–34852. 93 indexed citations

15.

Turton, R., John A. Chaddock, & K. Ravi Acharya. (2002). Botulinum and tetanus neurotoxins: structure, function and therapeutic utility. Trends in Biochemical Sciences. 27(11). 552–558. 274 indexed citations

16.

Chaddock, John A., John R. Purkiss, Michael Duggan, et al.. (2000). A Conjugate Composed of Nerve Growth Factor Coupled to a Non-toxic Derivative ofClostridium botulinumNeurotoxin Type A can Inhibit Neurotransmitter Releasein Vitro. Growth Factors. 18(2). 147–155. 39 indexed citations

17.

Zhan, Jinbiao, Maria de Sousa, John A. Chaddock, Lynne M. Roberts, & Janet M. Lord. (1997). Restoration of lectin activity to a non‐glycosylated ricin B chain mutant by the introduction of a novel N‐glycosylation site. FEBS Letters. 407(3). 271–274. 10 indexed citations

18.

Chaddock, John A., A.F. Monzingo, Jon D. Robertus, Janet M. Lord, & Lynne M. Roberts. (1996). Major Structural Differences between Pokeweed Antiviral Protein and Ricin A‐Chain do not Account for their Differing Ribosome Specificity. European Journal of Biochemistry. 235(1-2). 159–166. 24 indexed citations

19.

Chaddock, John A. & Lynne M. Roberts. (1993). Mutagenesis and kinetic analysis of the active site Glu177 of ricin A-chain. Protein Engineering Design and Selection. 6(4). 425–431. 39 indexed citations

20.

Wales, Richard, John A. Chaddock, Lynne M. Roberts, & Janet M. Lord. (1992). Addition of an ER retention signal to the ricin A chain increases the cytotoxicity of the holotoxin. Experimental Cell Research. 203(1). 1–4. 47 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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