Jérôme Hert

4.0k total citations · 1 hit paper
23 papers, 2.9k citations indexed

About

Jérôme Hert is a scholar working on Molecular Biology, Computational Theory and Mathematics and Pharmacology. According to data from OpenAlex, Jérôme Hert has authored 23 papers receiving a total of 2.9k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Molecular Biology, 18 papers in Computational Theory and Mathematics and 4 papers in Pharmacology. Recurrent topics in Jérôme Hert's work include Computational Drug Discovery Methods (18 papers), Metabolomics and Mass Spectrometry Studies (5 papers) and Protein Structure and Dynamics (4 papers). Jérôme Hert is often cited by papers focused on Computational Drug Discovery Methods (18 papers), Metabolomics and Mass Spectrometry Studies (5 papers) and Protein Structure and Dynamics (4 papers). Jérôme Hert collaborates with scholars based in Switzerland, United Kingdom and United States. Jérôme Hert's co-authors include Brian K. Shoichet, John J. Irwin, Michael J. Keiser, Christian Laggner, Peter Willett, David J. Wilton, Khalil Azzaoui, Edgar Jacoby, Pierre Acklin and Ansgar Schuffenhauer and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Medicinal Chemistry.

In The Last Decade

Jérôme Hert

23 papers receiving 2.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Predicting new molecular targets for known drugs

2009 1.3k citations Michael J. Keiser, Vincent Setola et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jérôme Hert Switzerland	18	2.0k	1.9k	488	372	355	23	2.9k
Christian Laggner Austria	31	1.8k 0.9×	2.6k 1.3×	663 1.4×	656 1.8×	222 0.6×	56	4.1k
Michael J. Keiser United States	25	3.1k 1.5×	3.3k 1.7×	886 1.8×	536 1.4×	429 1.2×	51	5.5k
Jacques Hamon Switzerland	16	1.6k 0.8×	1.7k 0.9×	406 0.8×	258 0.7×	143 0.4×	25	3.0k
Michał Nowotka United Kingdom	8	2.2k 1.1×	2.1k 1.1×	493 1.0×	353 0.9×	587 1.7×	11	3.3k
Manuel Pastor Spain	30	1.4k 0.7×	1.8k 0.9×	244 0.5×	572 1.5×	257 0.7×	99	3.1k
George Papadatos United Kingdom	19	3.0k 1.5×	3.0k 1.5×	624 1.3×	455 1.2×	793 2.2×	27	4.5k
Sheng Tian China	30	1.5k 0.7×	2.6k 1.4×	382 0.8×	644 1.7×	361 1.0×	88	4.3k
Ewgenij Proschak Germany	35	1.3k 0.6×	2.2k 1.1×	803 1.6×	1.4k 3.7×	325 0.9×	170	4.7k
Anneli Karlsson Sweden	9	1.5k 0.8×	2.6k 1.3×	345 0.7×	283 0.8×	395 1.1×	14	3.8k
Valerie J. Gillet United Kingdom	31	2.7k 1.3×	2.0k 1.0×	396 0.8×	607 1.6×	581 1.6×	101	3.7k

Countries citing papers authored by Jérôme Hert

Since Specialization

Citations

This map shows the geographic impact of Jérôme Hert's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jérôme Hert with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jérôme Hert more than expected).

Fields of papers citing papers by Jérôme Hert

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jérôme Hert. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jérôme Hert. The network helps show where Jérôme Hert may publish in the future.

Co-authorship network of co-authors of Jérôme Hert

This figure shows the co-authorship network connecting the top 25 collaborators of Jérôme Hert. A scholar is included among the top collaborators of Jérôme Hert based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jérôme Hert. Jérôme Hert is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Martin, Rainer E., Alexander L. Satz, Daniel Hunziker, et al.. (2025). Optimization of a DNA encoded library derived autotaxin inhibitor hit to a potent in vivo LPA lowering quinazolinone compound with a non‑zinc binding mode. Bioorganic & Medicinal Chemistry Letters. 123. 130221–130221. 3 indexed citations

Napoli, Joseph A., Michael Reutlinger, Peter Brandl, et al.. (2025). Multitask Deep Learning Models of Combined Industrial Absorption, Distribution, Metabolism, and Excretion Datasets to Improve Generalization. Molecular Pharmaceutics. 22(4). 1892–1900. 3 indexed citations

Hunziker, Daniel, Sabrina Reinehr, Natalie Wagner, et al.. (2022). Synthesis, Characterization, and in vivo Evaluation of a Novel Potent Autotaxin-Inhibitor. Frontiers in Pharmacology. 12. 699535–699535. 8 indexed citations

Awale, Mahendra, Jérôme Hert, Laura Guasch, Sereina Riniker, & Christian Krämer. (2021). The Playbooks of Medicinal Chemistry Design Moves. Journal of Chemical Information and Modeling. 61(2). 729–742. 14 indexed citations

Kuhn, Bernd, Michal Tichý, Lingle Wang, et al.. (2017). Prospective Evaluation of Free Energy Calculations for the Prioritization of Cathepsin L Inhibitors. Journal of Medicinal Chemistry. 60(6). 2485–2497. 101 indexed citations

Krämer, Christian, Attilla Ting, Hao Zheng, et al.. (2017). Learning Medicinal Chemistry Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) Rules from Cross-Company Matched Molecular Pairs Analysis (MMPA). Journal of Medicinal Chemistry. 61(8). 3277–3292. 67 indexed citations

Korb, Oliver, Bernd Kuhn, Jérôme Hert, et al.. (2016). Interactive and Versatile Navigation of Structural Databases. Journal of Medicinal Chemistry. 59(9). 4257–4266. 24 indexed citations

Kuhn, Bernd, Wolfgang Guba, Jérôme Hert, et al.. (2016). A Real-World Perspective on Molecular Design. Journal of Medicinal Chemistry. 59(9). 4087–4102. 80 indexed citations

Schulz‐Gasch, Tanja, et al.. (2013). CONFECT: Conformations from an Expert Collection of Torsion Patterns. ChemMedChem. 8(10). 1690–1700. 35 indexed citations

10.

Gregori‐Puigjané, Elisabet, Vincent Setola, Jérôme Hert, et al.. (2012). Identifying mechanism-of-action targets for drugs and probes. Proceedings of the National Academy of Sciences. 109(28). 11178–11183. 134 indexed citations

11.

Peters, Jens‐Uwe, Jérôme Hert, Caterina Bissantz, et al.. (2012). Can we discover pharmacological promiscuity early in the drug discovery process?. Drug Discovery Today. 17(7-8). 325–335. 59 indexed citations

12.

Keiser, Michael J., Vincent Setola, John J. Irwin, et al.. (2009). Predicting new molecular targets for known drugs. Nature. 462(7270). 175–181. 1251 indexed citations breakdown →

13.

Keiser, Michael J. & Jérôme Hert. (2009). Off-Target Networks Derived from Ligand Set Similarity. Methods in molecular biology. 575. 195–205. 19 indexed citations

14.

Hert, Jérôme, John J. Irwin, Christian Laggner, Michael J. Keiser, & Brian K. Shoichet. (2009). Quantifying biogenic bias in screening libraries. Nature Chemical Biology. 5(7). 479–483. 174 indexed citations

15.

Hert, Jérôme, Michael J. Keiser, John J. Irwin, Tudor I. Oprea, & Brian K. Shoichet. (2008). Quantifying the Relationships among Drug Classes. Journal of Chemical Information and Modeling. 48(4). 755–765. 124 indexed citations

16.

Hert, Jérôme, Peter Willett, David J. Wilton, et al.. (2006). New Methods for Ligand-Based Virtual Screening: Use of Data Fusion and Machine Learning to Enhance the Effectiveness of Similarity Searching. Journal of Chemical Information and Modeling. 46(2). 462–470. 167 indexed citations

17.

Hert, Jérôme, Peter Willett, David J. Wilton, et al.. (2005). Enhancing the Effectiveness of Similarity-Based Virtual Screening Using Nearest-Neighbor Information. Journal of Medicinal Chemistry. 48(22). 7049–7054. 57 indexed citations

18.

Chen, Beining, et al.. (2005). Ligand-based virtual screening using binary kernel discrimination. Molecular Simulation. 31(8). 597–604. 2 indexed citations

19.

Hert, Jérôme, Peter Willett, David J. Wilton, et al.. (2004). Comparison of topological descriptors for similarity-based virtual screening using multiple bioactive reference structures. Organic & Biomolecular Chemistry. 2(22). 3256–3256. 204 indexed citations

20.

Hert, Jérôme, Peter Willett, David J. Wilton, et al.. (2004). Comparison of Fingerprint-Based Methods for Virtual Screening Using Multiple Bioactive Reference Structures. Journal of Chemical Information and Computer Sciences. 44(3). 1177–1185. 239 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact