Jeff Holst

8.1k citations

79 papers · 4.8k indexed · 1 hit paper · h-index 37

Impact in

Biochemistry top 0.2%
- Amino Acid Enzymes and Metabolism
Cancer Research top 1%
- Cancer, Hypoxia, and Metabolism
- Cancer, Lipids, and Metabolism

Papers in ⓘ

Molecular Biology 54
- Epigenetics and DNA Methylation 19
- Polyamine Metabolism and Applications 6
- Natural product bioactivities and synthesis 5
Oncology 21
- Cancer-related Molecular Pathways 8
- CAR-T cell therapy research 6

Co-authors: Qian Wang (25 shared papers)John E.J. Rasko (28 shared papers)Charles G. Bailey (18 shared papers)Michelle van Geldermalsen (12 shared papers)William Ritchie (11 shared papers)Dario A.A. Vignali (5 shared papers)Annora Thoeng (9 shared papers)Dadi Gao (9 shared papers)
Journals: Journal of Biological Chemistry (3 papers)International Journal of Cancer (3 papers)Journal of Natural Products (3 papers)Journal of Hematology & Oncology (2 papers)Cancer Research (2 papers)
Partner nations: Australia United States United Kingdom

In The Last Decade

Jeff Holst

75 papers receiving 4.8k citations

Hit Papers

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ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer 2015 · 478 citations

Peers

Countries citing papers authored by Jeff Holst

Since Specialization

Citations

This map shows the geographic impact of Jeff Holst's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jeff Holst with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jeff Holst more than expected).

Fields of papers citing papers by Jeff Holst

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jeff Holst. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jeff Holst. The network helps show where Jeff Holst may publish in the future.

Co-authors

The 25 scholars most cited alongside Jeff Holst, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jeff Holst Line = papers co-authored together Jeff Holst links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 79 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer Oncogene ·Michelle van Geldermalsen, Qian Wang, Rajini Nagarajah, Amy D. Marshall, Annora Thoeng, Dadi Gao, William Ritchie, Yongmei Feng, Charles G. Bailey, Niantao Deng, Kate Harvey, Jane Beith, Christina Selinger, Sandra O’Toole, John E.J. Rasko, Jeff Holst Hit paper breakdown →	2015	478
2	Orchestrated Intron Retention Regulates Normal Granulocyte Differentiation Cell ·Justin Wong, William Ritchie, Olivia A. Ebner, Matthias Selbach, Jason W.H. Wong, Yizhou Huang, Dadi Gao, Natalia Pinello, Maria Gonzalez, Kinsha Baidya, Annora Thoeng, Teh‐Liane Khoo, Charles G. Bailey, Jeff Holst, John E.J. Rasko	2013	344
3	Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration Cancer & Metabolism ·Seher Balaban, Robert F. Shearer, Lisa S. Lee, Michelle van Geldermalsen, Mark Schreuder, Harrison C. Shtein, Rose Cairns, Kristen C. Thomas, Daniel J. Fazakerley, Thomas Grewal, Jeff Holst, Darren N. Saunders, Andrew J. Hoy	2017	329
4	L-type amino acid transport and cancer: targeting the mTORC1 pathway to inhibit neoplasia. PubMed ·Qian Wang, Jeff Holst	2015	237
5	Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells Nature Biotechnology ·Jeff Holst, Sarah L. Watson, Megan S. Lord, Steven S. Eamegdool, Daniel V. Bax, Lisa Nivison‐Smith, Alexey Kondyurin, Liang Ma, Andrés F. Oberhauser, Anthony S. Weiss, John E.J. Rasko	2010	217
6	Generation of T-cell receptor retrogenic mice Nature Protocols ·Jeff Holst, Andrea L. Szymczak-Workman, Kate M. Vignali, Amanda R. Burton, Creg J. Workman, Dario A.A. Vignali	2006	216
7	General Nature of the STAT3-Activated Anti-Inflammatory Response The Journal of Immunology ·Karim C. El Kasmi, Jeff Holst, Maryaline Coffre, Lisa A. Mielke, Antoine De Pauw, Nouara Lhocine, Amber M. Smith, Robert Rutschman, Deepak Kaushal, Yuhong Shen, Takashi Suda, Raymond P. Donnelly, Martin G. Myers, Warren S. Alexander, Dario A.A. Vignali, Stephanie S. Watowich, Matthias Ernst, Douglas J. Hilton, Peter J. Murray	2006	186
8	Targeting glutamine transport to suppress melanoma cell growth International Journal of Cancer ·Qian Wang, Kimberley A. Beaumont, Nicholas Otte, Josep Font, Charles G. Bailey, Michelle van Geldermalsen, Danae M. Sharp, Jessamy Tiffen, Renae M. Ryan, Mika Jormakka, Nikolas K. Haass, John E.J. Rasko, Jeff Holst	2014	182
9	Targeting Amino Acid Transport in Metastatic Castration-Resistant Prostate Cancer: Effects on Cell Cycle, Cell Growth, and Tumor Development JNCI Journal of the National Cancer Institute ·Qian Wang, Jessamy Tiffen, Charles G. Bailey, Melanie Lehman, William Ritchie, Ladan Fazli, Cynthia Metierre, Yue Feng, Estelle Li, Martin Gleave, Grant Buchanan, Colleen C. Nelson, John E.J. Rasko, Jeff Holst	2013	141
10	Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis eLife ·Zeyad D. Nassar, Chui Y. Mah, Jonas Dehairs, Ingrid J.G. Burvenich, Swati Irani, Margaret M. Centenera, Madison Helm, Raj K. Shrestha, Max Moldovan, Anthony S. Don, Jeff Holst, Andrew M. Scott, Lisa G. Horvath, David J. Lynn, Luke A. Selth, Andrew J. Hoy, Johannes V. Swinnen, Lisa M. Butler	2020	140
11	Androgen Receptor and Nutrient Signaling Pathways Coordinate the Demand for Increased Amino Acid Transport during Prostate Cancer Progression Cancer Research ·Qian Wang, Charles G. Bailey, Cynthia Ng, Jessamy Tiffen, Annora Thoeng, Vineet Minhas, Melanie Lehman, Stephen C. Hendy, Grant Buchanan, Colleen C. Nelson, John E.J. Rasko, Jeff Holst	2011	135
12	Scalable signaling mediated by T cell antigen receptor–CD3 ITAMs ensures effective negative selection and prevents autoimmunity Nature Immunology ·Jeff Holst, Haopeng Wang, Kelly Durick Eder, Creg J. Workman, Kelli L. Boyd, Zachary C. Baquet, Harvir Singh, Karen Forbes, Andrzej Chruscinski, Richard J. Smeyne, Nicolai S. C. van Oers, Paul J. Utz, Dario A.A. Vignali	2008	131
13	Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans Nature Structural & Molecular Biology ·Ryan J. Taft, Cas Simons, Satu Nahkuri, Harald Oey, Darren Korbie, Tim R. Mercer, Jeff Holst, William Ritchie, Justin Wong, John E.J. Rasko, Daniel S. Rokhsar, Bernard M. Degnan, John S. Mattick	2010	128
14	Rapid analysis of T-cell selection in vivo using T cell–receptor retrogenic mice Nature Methods ·Jeff Holst, Kate M. Vignali, Amanda R. Burton, Dario A.A. Vignali	2006	127
15	Micro-RNA response to imatinib mesylate in patients with chronic myeloid leukemia Haematologica ·Stéphane Flamant, William Ritchie, Joëlle Guilhot, Jeff Holst, Marie Laure Bonnet, Jean‐Claude Chomel, François Guilhot, Ali G. Turhan, John E.J. Rasko	2010	91
16	p27Kip1 signaling: Transcriptional and post-translational regulation The International Journal of Biochemistry & Cell Biology ·Su Su Thae Hnit, Chanlu Xie, Yao Mu, Jeff Holst, Alan Bensoussan, Paul de Souza, Zhong Li, Qihan Dong	2015	86
17	Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo Molecular Cancer ·Jessamy Tiffen, Charles G. Bailey, Cynthia Ng, John E.J. Rasko, Jeff Holst	2010	79
18	Intron retention is regulated by altered MeCP2-mediated splicing factor recruitment Nature Communications ·Justin Wong, Dadi Gao, Trung Viet Nguyen, Chau‐To Kwok, Michelle van Geldermalsen, Rob Middleton, Natalia Pinello, Annora Thoeng, Rajini Nagarajah, Jeff Holst, William Ritchie, John E.J. Rasko	2017	76
19	Ablation of the ASCT2 (SLC1A5) gene encoding a neutral amino acid transporter reveals transporter plasticity and redundancy in cancer cells Journal of Biological Chemistry ·Angelika Bröer, Gregory Gauthier-Coles, Farid Rahimi, Michelle van Geldermalsen, Dieter Dorsch, Ansgar Wegener, Jeff Holst, Stefan Bröer	2019	76
20	Impaired Nutrient Signaling and Body Weight Control in a Na+ Neutral Amino Acid Cotransporter (Slc6a19)-deficient Mouse Journal of Biological Chemistry ·Angelika Bröer, Torsten Juelich, Jessica M. Vanslambrouck, Nadine Tietze, Peter S. Solomon, Jeff Holst, Charles G. Bailey, John E.J. Rasko, Stefan Bröer	2011	69

About Jeff Holst

Jeff Holst is a scholar working on Molecular Biology, Oncology, Biochemistry, Cancer Research and Immunology, having authored 79 papers that have together received 4.8k indexed citations. Recurring topics across this work include Amino Acid Enzymes and Metabolism (21 papers), Epigenetics and DNA Methylation (19 papers), Cancer-related Molecular Pathways (8 papers), Natural Compounds in Disease Treatment (7 papers), CAR-T cell therapy research (6 papers), Cancer, Hypoxia, and Metabolism (6 papers), Polyamine Metabolism and Applications (6 papers) and Natural product bioactivities and synthesis (5 papers). The work is most often cited by research in Biochemistry (846 citations), Cancer Research (1.5k citations), Molecular Biology (3.0k citations), Immunology (827 citations) and Oncology (987 citations). Jeff Holst has collaborated with scholars based in Australia, United States and United Kingdom. Frequent co-authors include Qian Wang, John E.J. Rasko, Charles G. Bailey, Michelle van Geldermalsen, William Ritchie, Dario A.A. Vignali, Annora Thoeng, Dadi Gao, Kate M. Vignali and Amanda R. Burton. Their work appears in journals such as Journal of Biological Chemistry, International Journal of Cancer, Journal of Natural Products, Journal of Hematology & Oncology and Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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