Jean‐Christophe Amé

7.0k total citations · 4 hit papers
32 papers, 5.8k citations indexed

About

Jean‐Christophe Amé is a scholar working on Oncology, Molecular Biology and Immunology. According to data from OpenAlex, Jean‐Christophe Amé has authored 32 papers receiving a total of 5.8k indexed citations (citations by other indexed papers that have themselves been cited), including 32 papers in Oncology, 21 papers in Molecular Biology and 12 papers in Immunology. Recurrent topics in Jean‐Christophe Amé's work include PARP inhibition in cancer therapy (31 papers), DNA Repair Mechanisms (18 papers) and Toxin Mechanisms and Immunotoxins (12 papers). Jean‐Christophe Amé is often cited by papers focused on PARP inhibition in cancer therapy (31 papers), DNA Repair Mechanisms (18 papers) and Toxin Mechanisms and Immunotoxins (12 papers). Jean‐Christophe Amé collaborates with scholars based in France, United States and Germany. Jean‐Christophe Amé's co-authors include Gilbert de Murcia, Valérie Schreiber, Françoise Dantzer, Catherine Spenlehauer, Josiane Ménissier‐de Murcia, Elaine L. Jacobson, Myron K. Jacobson, Heinrich Leonhardt, Oliver Mortusewicz and Valérie Fraulob and has published in prestigious journals such as Nucleic Acids Research, Journal of Biological Chemistry and Nature Reviews Molecular Cell Biology.

In The Last Decade

Jean‐Christophe Amé

32 papers receiving 5.8k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Poly(ADP-ribose): novel functions for an old molecule

2006 1.6k citations Valérie Schreiber, Françoise Dantzer et al. Nature Reviews Molecular Cell Biology profile →
The PARP superfamily

2004 1.2k citations Jean‐Christophe Amé, Catherine Spenlehauer et al. BioEssays profile →
PARP-2, A Novel Mammalian DNA Damage-dependent Poly(ADP-ribose) Polymerase

1999 616 citations Jean‐Christophe Amé, Valérie Schreiber et al. Journal of Biological Chemistry profile →
Poly(ADP-ribose) Polymerase-2 (PARP-2) Is Required for Efficient Base Excision DNA Repair in Association with PARP-1 and XRCC1

2002 573 citations Valérie Schreiber, Jean‐Christophe Amé et al. Journal of Biological Chemistry profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
Jean‐Christophe Amé	4.6k	4.0k	1.1k	780	642	32	5.8k
Françoise Dantzer	5.0k 1.1×	4.9k 1.2×	1.1k 1.1×	752 1.0×	672 1.0×	89	7.2k
Josiane Ménissier‐de Murcia	4.4k 1.0×	5.2k 1.3×	901 0.8×	563 0.7×	538 0.8×	42	7.2k
Josiane Ménissier de Murcia	2.2k 0.5×	2.2k 0.6×	503 0.5×	271 0.3×	264 0.4×	17	3.1k
Damien D’Amours	2.1k 0.5×	4.0k 1.0×	454 0.4×	225 0.3×	212 0.3×	49	4.9k
Yonghao Yu	1.2k 0.3×	3.4k 0.8×	562 0.5×	207 0.3×	177 0.3×	93	4.7k
Ralph Imhof	1.3k 0.3×	2.0k 0.5×	433 0.4×	150 0.2×	238 0.4×	27	2.7k
Jean‐Philippe Gagné	1.3k 0.3×	1.8k 0.4×	322 0.3×	175 0.2×	183 0.3×	50	2.4k
Masahiko S. Satoh	1.6k 0.3×	2.3k 0.6×	347 0.3×	157 0.2×	136 0.2×	47	3.1k
Denis Biard	1.2k 0.3×	2.5k 0.6×	255 0.2×	84 0.1×	80 0.1×	73	3.1k
Donatella Del Bufalo	1.4k 0.3×	3.0k 0.8×	650 0.6×	14 0.0×	192 0.3×	133	4.7k

Countries citing papers authored by Jean‐Christophe Amé

Since Specialization

Citations

This map shows the geographic impact of Jean‐Christophe Amé's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jean‐Christophe Amé with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jean‐Christophe Amé more than expected).

Fields of papers citing papers by Jean‐Christophe Amé

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jean‐Christophe Amé. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jean‐Christophe Amé. The network helps show where Jean‐Christophe Amé may publish in the future.

Co-authorship network of co-authors of Jean‐Christophe Amé

This figure shows the co-authorship network connecting the top 25 collaborators of Jean‐Christophe Amé. A scholar is included among the top collaborators of Jean‐Christophe Amé based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jean‐Christophe Amé. Jean‐Christophe Amé is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Amé, Jean‐Christophe, et al.. (2022). PARP3 supervises G9a-mediated repression of adhesion and hypoxia-responsive genes in glioblastoma cells. Scientific Reports. 12(1). 15534–15534. 7 indexed citations

Amé, Jean‐Christophe & Françoise Dantzer. (2022). Purification of Recombinant Human PARG and Activity Assays. Methods in molecular biology. 2609. 399–418. 1 indexed citations

Waïssi, Waïsse, Jean‐Christophe Amé, Carole Mura, G. Noël, & Hélène Burckel. (2021). Gemcitabine-Based Chemoradiotherapy Enhanced by a PARP Inhibitor in Pancreatic Cancer Cell Lines. International Journal of Molecular Sciences. 22(13). 6825–6825. 14 indexed citations

Rodríguez-Vargas, José Manuel, Wei Wang, Rajikala Suganthan, et al.. (2020). Parp3 promotes astrocytic differentiation through a tight regulation of Nox4-induced ROS and mTorc2 activation. Cell Death and Disease. 11(11). 954–954. 21 indexed citations

Amé, Jean‐Christophe, et al.. (2017). Purification of Recombinant Human PARG and Activity Assays. Methods in molecular biology. 1608. 395–413. 8 indexed citations

Amé, Jean‐Christophe, et al.. (2017). Purification of Recombinant Human PARP-3. Methods in molecular biology. 1608. 373–394. 3 indexed citations

Illuzzi, Giuditta, et al.. (2016). PARG deficiency is neither synthetic lethal with BRCA1 nor PTEN deficiency. Cancer Cell International. 16(1). 53–53. 17 indexed citations

Kutuzov, Mikhail M., С. Н. Ходырева, Ekaterina S. Ilina, et al.. (2015). Interaction of PARP-2 with AP site containing DNA. Biochimie. 112. 10–19. 36 indexed citations

Illuzzi, Giuditta, Elise Fouquerel, Jean‐Christophe Amé, et al.. (2014). PARG is dispensable for recovery from transient replicative stress but required to prevent detrimental accumulation of poly(ADP-ribose) upon prolonged replicative stress. Nucleic Acids Research. 42(12). 7776–7792. 58 indexed citations

10.

Kutuzov, Mikhail M., С. Н. Ходырева, Jean‐Christophe Amé, et al.. (2013). Interaction of PARP-2 with DNA structures mimicking DNA repair intermediates and consequences on activity of base excision repair proteins. Biochimie. 95(6). 1208–1215. 53 indexed citations

11.

May, Nicolas Le, Jean‐Christophe Amé, Alexander S. Zhovmer, et al.. (2012). Poly (ADP-Ribose) Glycohydrolase Regulates Retinoic Acid Receptor-Mediated Gene Expression. Molecular Cell. 48(5). 785–798. 44 indexed citations

12.

Amé, Jean‐Christophe, et al.. (2012). New readers and interpretations of poly(ADP-ribosyl)ation. Trends in Biochemical Sciences. 37(9). 381–390. 69 indexed citations

13.

Amé, Jean‐Christophe, et al.. (2011). Purification of Recombinant Poly(ADP-Ribose) Polymerases. Methods in molecular biology. 780. 135–152. 24 indexed citations

14.

Amé, Jean‐Christophe, et al.. (2008). Detection of the Nuclear Poly(ADP-ribose)-Metabolizing Enzymes and Activities in Response to DNA Damage. Methods in molecular biology. 464. 267–283. 13 indexed citations

15.

Mortusewicz, Oliver, Jean‐Christophe Amé, Valérie Schreiber, & Heinrich Leonhardt. (2007). Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells. Nucleic Acids Research. 35(22). 7665–7675. 265 indexed citations

16.

Schreiber, Valérie, Françoise Dantzer, Jean‐Christophe Amé, & Gilbert de Murcia. (2006). Poly(ADP-ribose): novel functions for an old molecule. Nature Reviews Molecular Cell Biology. 7(7). 517–528. 1572 indexed citations breakdown →

17.

Amé, Jean‐Christophe, Catherine Spenlehauer, & Gilbert de Murcia. (2004). The PARP superfamily. BioEssays. 26(8). 882–893. 1221 indexed citations breakdown →

18.

Schreiber, Valérie, Jean‐Christophe Amé, Pascal Dollé, et al.. (2002). Poly(ADP-ribose) Polymerase-2 (PARP-2) Is Required for Efficient Base Excision DNA Repair in Association with PARP-1 and XRCC1. Journal of Biological Chemistry. 277(25). 23028–23036. 573 indexed citations breakdown →

19.

Shieh, Woan-Ru, Jean‐Christophe Amé, Melinda R. Wilson, et al.. (1998). Poly(ADP-ribose) Polymerase Null Mouse Cells Synthesize ADP-ribose Polymers. Journal of Biological Chemistry. 273(46). 30069–30072. 263 indexed citations

20.

Amé, Jean‐Christophe, et al.. (1997). Isolation and Characterization of the cDNA Encoding Bovine Poly(ADP-ribose) Glycohydrolase. Journal of Biological Chemistry. 272(18). 11895–11901. 181 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact