Jan Hofsteenge

10.3k citations

115 papers · 8.5k indexed · 2 hit papers · h-index 53

Impact in

Hematology top 0.5%
- Blood Coagulation and Thrombosis Mechanisms
Molecular Biology top 1%
- Glycosylation and Glycoproteins Research
- RNA and protein synthesis mechanisms
- Protein Structure and Dynamics

Papers in

Hematology 26
- Blood Coagulation and Thrombosis Mechanisms 23
Cancer Research 19
- Protease and Inhibitor Mechanisms 19

Co-authors: Stuart R. Stone Brian A. Hemmings Daniel Heß Wolfram Bode Robert Huber Irmgard Mayr Ulrich Baumann Paul Braun
Journals: Biochemistry (28 papers)Journal of Biological Chemistry (19 papers)European Journal of Biochemistry (12 papers)Biochemical Journal (8 papers)Nucleic Acids Research (4 papers)
Partner nations: Switzerland Netherlands United States

In The Last Decade

Jan Hofsteenge

115 papers receiving 8.3k citations

Hit Papers

align trajectories log scale

The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment. 1989 · 794 citations

Peers

Countries citing papers authored by Jan Hofsteenge

Since Specialization

Citations

This map shows the geographic impact of Jan Hofsteenge's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jan Hofsteenge with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jan Hofsteenge more than expected).

Fields of papers citing papers by Jan Hofsteenge

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jan Hofsteenge. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jan Hofsteenge. The network helps show where Jan Hofsteenge may publish in the future.

Co-authors

The 25 scholars most cited alongside Jan Hofsteenge, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jan Hofsteenge Line = papers co-authored together Jan Hofsteenge links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Identification and Characterization of aβ1,3-Glucosyltransferase That Synthesizes the Glc-β1,3-Fuc Disaccharide on Thrombospondin Type 1 Repeats Journal of Biological Chemistry ·Lamin ELARBAH, J.J. Keusch, Björn Hegemann, Kelvin B. Luther, Dominique Klein, Daniel Heß, Robert S. Haltiwanger, Jan Hofsteenge	2006	67
2	The patatin-like protein from the latex of Hevea brasiliensis (Hev b 7) is not a vacuolar protein Phytochemistry ·Peter A. Jekel, Jan Hofsteenge, Jaap J. Beintema	2003	7
3	Requirement of the Lec35 Gene for All Known Classes of Monosaccharide-P-Dolichol-dependent Glycosyltransferase Reactions in Mammals Molecular Biology of the Cell ·Monika Anand, Jeffrey S. Rush, Sutapa Ray, Marie‐Agnès Doucey, Meng Qing-h, 김창용, Jan Hofsteenge, Charles J. Waechter, Mark A. Lehrman	2001	74
4	High-Level Soluble Production and Characterization of Porcine Ribonuclease Inhibitor Protein Expression and Purification ·Tony A. Klink, Anna M. Vicentini, Jan Hofsteenge, Ronald T. Raines	2001	27
5	Direct determination of glycosylation sites in O‐fucosylated glycopeptides using nano‐electrospray quadrupole time‐of‐flight mass spectrometry Rapid Communications in Mass Spectrometry ·Boris Maček, Jan Hofsteenge, Jasna Peter‐Katalinić	2001	31
6	Identification of Tyrosine Phosphorylation Sites on 3-Phosphoinositide-dependent Protein Kinase-1 and Their Role in Regulating Kinase Activity Journal of Biological Chemistry ·Jongsun Park, Michelle M. Hill, Daniel Heß, Derek P. Brazil, Jan Hofsteenge, Brian A. Hemmings	2001	105
7	Functional Expression of Human PP2Ac in Yeast Permits the Identification of Novel C-terminal and Dominant-negative Mutant Forms Journal of Biological Chemistry ·David R. Evans, Timothy Myles, Jan Hofsteenge, Brian A. Hemmings	1999	58
8	The Four Terminal Components of the Complement System AreC-Mannosylated on Multiple Tryptophan Residues Journal of Biological Chemistry ·Jan Hofsteenge, Marcel J. J. Blommers, Daniel Heß, Douglas DePrekel, Parya Fathi	1999	82
9	Recognition Signal for C-Mannosylation of Trp-7 in RNase 2 Consists of Sequence Trp-x-x-Trp Molecular Biology of the Cell ·Joachim Krieg, Steffen Hartmann, Anna M. Vicentini, Patrick Bonnel, Daniel Heß, Jan Hofsteenge	1998	113
10	Crystallization of Porcine Liver Ribonuclease Inhibitor a Member of the Family of Proteins Containing Leucine-rich Repeats Journal of Molecular Biology ·Ulf Neumann, Jan Hofsteenge, Ayesha Kiran, Bauke W. Dijkstra	1993	4
11	Residues 287–301 of human ribonuclease inhibitor do not affect ribonuclease activity and inhibitor binding; a reply Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology ·Jesús Fominaya, Ulf Neumann, Jan Hofsteenge	1993	1
12	Purification and characterization of a soluble β‐fructofuranosidase from Daucus carota European Journal of Biochemistry ·Christoph Unger, Jan Hofsteenge, Arnd Sturm	1992	49
13	Recombinant hirudin: kinetic mechanism for the inhibition of human thrombin Protein Engineering Design and Selection ·Stuart R. Stone, Jan Hofsteenge	1991	10
14	Mechanistic studies on thrombin catalysis Biochemistry ·Stuart R. Stone, Andreas Betz, Jan Hofsteenge	1991	48
15	cDNA cloning of porcine brain prolyl endopeptidase and identification of the active-site seryl residue Biochemistry ·Paolo Rossitto, Brian A. Hemmings, Jan Hofsteenge, Stuart R. Stone	1991	134
16	Basis for the reduced affinity of .beta.T- and .gamma.T-thrombin for hirudin Biochemistry ·Stuart R. Stone, Jan Hofsteenge	1991	24
17	Role of interactions involving C-terminal nonpolar residues of hirudin in the formation of the thrombin-hirudin complex Biochemistry ·Andreas Betz, Jan Hofsteenge, Stuart R. Stone	1991	38
18	Protein chemical and kinetic characterization of recombinant porcine ribonuclease inhibitor expressed in Saccharomyces cerevisiae Biochemistry ·Anna M. Vicentini, Brigitte L. Kieffer, Lawrence V, Bernd Meyhack, Brian A. Hemmings, Stuart R. Stone, Jan Hofsteenge	1990	75
19	The nucleotide sequence of the cDNA encoding the human lung protein phosphatase 2Aβ catalytic subunit Nucleic Acids Research ·Brian A. Hemmings, Wolfgang Wernet, Regina Mayer, Johanna Lomker, Jan Hofsteenge, Stuart R. Stone	1988	16
20	cDNA sequence coding for a rat glia-derived nexin and its homology to members of the serpin superfamily Biochemistry ·زولتان برانتنر, Sergio M. Gloor, Giorgio Rovelli, Jan Hofsteenge, Hanspeter Nick, Roland Meier, Denis Monard	1987	99

About Jan Hofsteenge

Jan Hofsteenge is a scholar working on Hematology, Cancer Research, Molecular Biology, Biotechnology and Biochemistry, having authored 115 papers that have together received 8.5k indexed citations. Recurring topics across this work include Enzyme Structure and Function (24 papers), Blood Coagulation and Thrombosis Mechanisms (23 papers), Glycosylation and Glycoproteins Research (20 papers), Protease and Inhibitor Mechanisms (19 papers), RNA and protein synthesis mechanisms (18 papers), Peptidase Inhibition and Analysis (13 papers), Protein Structure and Dynamics (10 papers) and Biochemical and Molecular Research (8 papers). The work is most often cited by research in Hematology (2.0k citations), Molecular Biology (5.3k citations), Cancer Research (1.0k citations), Immunology and Allergy (408 citations) and Cell Biology (950 citations). Jan Hofsteenge has collaborated with scholars based in Switzerland, Netherlands and United States. Frequent co-authors include Stuart R. Stone, Brian A. Hemmings, Daniel Heß, Wolfram Bode, Robert Huber, Irmgard Mayr, Ulrich Baumann, Paul Braun, S. M. Dennis and Jaap J. Beintema. Their work appears in journals such as Biochemistry, Journal of Biological Chemistry, European Journal of Biochemistry, Biochemical Journal and Nucleic Acids Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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