James Onuffer

2.5k total citations · 1 hit paper
25 papers, 2.0k citations indexed

About

James Onuffer is a scholar working on Molecular Biology, Immunology and Materials Chemistry. According to data from OpenAlex, James Onuffer has authored 25 papers receiving a total of 2.0k indexed citations (citations by other indexed papers that have themselves been cited), including 16 papers in Molecular Biology, 10 papers in Immunology and 10 papers in Materials Chemistry. Recurrent topics in James Onuffer's work include Enzyme Structure and Function (10 papers), Protein Structure and Dynamics (6 papers) and Chemokine receptors and signaling (6 papers). James Onuffer is often cited by papers focused on Enzyme Structure and Function (10 papers), Protein Structure and Dynamics (6 papers) and Chemokine receptors and signaling (6 papers). James Onuffer collaborates with scholars based in United States, Germany and Spain. James Onuffer's co-authors include Wendell A. Lim, Richard Horuk, Chia-Yung Wu, Elias M. Puchner, Kole T. Roybal, Jack F. Kirsch, C. Robert Matthews, Michael Frink, Volker Vielhauer and Hans‐Joachim Anders and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

James Onuffer

25 papers receiving 1.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Remote control of therapeutic T cells through a small molecule–gated chimeric receptor

2015 552 citations James Onuffer, Wendell A. Lim et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
James Onuffer United States	18	1.1k	756	451	313	270	25	2.0k
Vadim V. Sumbayev United Kingdom	29	1.0k 0.9×	385 0.5×	1.2k 2.6×	113 0.4×	110 0.4×	70	2.5k
Lou de Leij Netherlands	23	1.0k 0.9×	483 0.6×	380 0.8×	193 0.6×	72 0.3×	51	1.9k
A Nicolin Italy	27	1.3k 1.2×	510 0.7×	417 0.9×	265 0.8×	109 0.4×	105	2.4k
Fei Huang United States	30	2.0k 1.8×	483 0.6×	291 0.6×	78 0.2×	141 0.5×	114	2.9k
Peter McCourt Norway	28	972 0.9×	210 0.3×	434 1.0×	271 0.9×	51 0.2×	66	2.7k
Laura E. Herring United States	26	1.6k 1.5×	616 0.8×	796 1.8×	560 1.8×	68 0.3×	100	2.9k
Akihiko Tsuji Japan	28	1.5k 1.4×	299 0.4×	150 0.3×	206 0.7×	74 0.3×	127	2.7k
Alan Sabirsh Sweden	24	1.3k 1.2×	134 0.2×	329 0.7×	181 0.6×	56 0.2×	45	2.3k
Ahmed Hamaï France	22	1.8k 1.7×	1.1k 1.4×	1.1k 2.4×	312 1.0×	49 0.2×	39	3.6k
Wendy Sandoval United States	32	2.4k 2.2×	497 0.7×	507 1.1×	174 0.6×	64 0.2×	78	3.5k

Countries citing papers authored by James Onuffer

Since Specialization

Citations

This map shows the geographic impact of James Onuffer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James Onuffer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James Onuffer more than expected).

Fields of papers citing papers by James Onuffer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James Onuffer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James Onuffer. The network helps show where James Onuffer may publish in the future.

Co-authorship network of co-authors of James Onuffer

This figure shows the co-authorship network connecting the top 25 collaborators of James Onuffer. A scholar is included among the top collaborators of James Onuffer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James Onuffer. James Onuffer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

1.

Hu, Jianfang, Benjamin Lopez, Tiffany Lam, et al.. (2019). Abstract 3189: CAB-CAR-T: A novel conditionally active biologics approach to minimize on-target off-tumor effects in adoptive immunotherapy. Immunology. 3189–3189. 1 indexed citations

2.

Wei, Ping, Wilson W. Wong, Jason S. Park, et al.. (2012). Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells. Nature. 488(7411). 384–388. 101 indexed citations

3.

Dunning, Laura, Stefan Jaroch, Karen May, et al.. (2007). CCR5 receptor antagonists: Discovery and SAR of novel 4-hydroxypiperidine derivatives. Bioorganic & Medicinal Chemistry Letters. 17(7). 1883–1887. 15 indexed citations

4.

Arnaiz, Damian O., Laura Dunning, Wheeseong Lee, et al.. (2006). CCR5 receptor antagonists: Discovery and SAR study of guanylhydrazone derivatives. Bioorganic & Medicinal Chemistry Letters. 17(1). 231–234. 16 indexed citations

5.

Onuffer, James, Margaret A. McCarrick, Laura Dunning, et al.. (2003). Structure Function Differences in Nonpeptide CCR1 Antagonists for Human and Mouse CCR1. The Journal of Immunology. 170(4). 1910–1916. 19 indexed citations

6.

Anders, Hans‐Joachim, Volker Vielhauer, Michael Frink, et al.. (2002). A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation. Journal of Clinical Investigation. 109(2). 251–259. 6 indexed citations

7.

Onuffer, James & Richard Horuk. (2002). Chemokines, chemokine receptors and small-molecule antagonists: recent developments. Trends in Pharmacological Sciences. 23(10). 459–467. 167 indexed citations

8.

Anders, Hans‐Joachim, Volker Vielhauer, Michael Frink, et al.. (2002). A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation. Journal of Clinical Investigation. 109(2). 251–259. 180 indexed citations

9.

Anders, Hans‐Joachim, Volker Vielhauer, Michael Frink, et al.. (2002). A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation. Journal of Clinical Investigation. 109(2). 251–259. 160 indexed citations

10.

Verde, Ignácio, Gudrun Pahlke, Michele Salanova, et al.. (2001). Myomegalin Is a Novel Protein of the Golgi/Centrosome That Interacts with a Cyclic Nucleotide Phosphodiesterase. Journal of Biological Chemistry. 276(14). 11189–11198. 171 indexed citations

11.

Dinter, Harald, Jenny Tse, Meredith Halks‐Miller, et al.. (2000). The type IV phosphodiesterase specific inhibitor mesopram inhibits experimental autoimmune encephalomyelitis in rodents. Journal of Neuroimmunology. 108(1-2). 136–146. 43 indexed citations

12.

Dinter, Harald, James Onuffer, Daryl Faulds, & H. Daniel Perez. (1997). Phosphodiesterase type IV inhibitors in the treatment of multiple sclerosis. Journal of Molecular Medicine. 75(2). 95–102. 18 indexed citations

13.

Onuffer, James, et al.. (1995). The use of natural and unnatural amino acid substrates to define the substrate specificity differences ofescherichia coliaspartate and tyrosine aminotransferases. Protein Science. 4(9). 1743–1749. 25 indexed citations

14.

Malashkevich, V.N., James Onuffer, Jack F. Kirsch, & Johan N. Jansonius. (1995). Alternating arginine-modulated substrate specificity in an engineered tyrosine aminotransferase. Nature Structural Biology. 2(7). 548–553. 56 indexed citations

15.

Onuffer, James, et al.. (1995). Redesign of the substrate specificity ofescherichia coliaspartate aminotransferase to that ofescherichia colityrosine aminotransferase by homology modeling and site-directed mutagenesis. Protein Science. 4(9). 1750–1757. 62 indexed citations

16.

Onuffer, James & Jack F. Kirsch. (1994). Characterization of the apparent negative co-operativity induced in Escherichia coli aspartate aminotransferase by the replacement of Asp222 with alanine. Evidence for an extremely slow conformational change. Protein Engineering Design and Selection. 7(3). 413–424. 46 indexed citations

17.

Cioni, Patrizia, James Onuffer, & Giovanni B. Strambini. (1992). Characterization of tryptophan phosphorescence of aspartate aminotransferase from Escherichia coli. European Journal of Biochemistry. 209(2). 759–764. 13 indexed citations

18.

Stackhouse, Thomas, et al.. (1988). Folding of homologous proteins: Conservation of the folding mechanism of the .alpha. subunit of tryptophan synthase from Escherichia coli, Salmonella typhimurium, and five interspecies hybrides. Biochemistry. 27(2). 824–832. 28 indexed citations

19.

Stackhouse, Thomas, James Onuffer, C. Robert Matthews, S. Ahmed, & Edith Wilson Miles. (1987). The Role of Protein Folding in the Evolution of Protein Sequences. Cold Spring Harbor Symposia on Quantitative Biology. 52(0). 537–544. 1 indexed citations

20.

Hurle, Mark R., et al.. (1986). Effects of the phenylalanine-22 .fwdarw. leucine, glutamic acid-49 .fwdarw. methionine, glycine-234 .fwdarw. aspartic acid and glycine-234 .fwdarw. lysine mutations on the folding and stability of the .alpha. subunit of tryptophan synthase from Escherichia coli. Biochemistry. 25(10). 2965–2974. 92 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact