Jack Lawler

24.8k total citations · 4 hit papers
206 papers, 20.2k citations indexed

About

Jack Lawler is a scholar working on Molecular Biology, Cancer Research and Cell Biology. According to data from OpenAlex, Jack Lawler has authored 206 papers receiving a total of 20.2k indexed citations (citations by other indexed papers that have themselves been cited), including 148 papers in Molecular Biology, 69 papers in Cancer Research and 40 papers in Cell Biology. Recurrent topics in Jack Lawler's work include Angiogenesis and VEGF in Cancer (123 papers), Protease and Inhibitor Mechanisms (54 papers) and Cell Adhesion Molecules Research (35 papers). Jack Lawler is often cited by papers focused on Angiogenesis and VEGF in Cancer (123 papers), Protease and Inhibitor Mechanisms (54 papers) and Cell Adhesion Molecules Research (35 papers). Jack Lawler collaborates with scholars based in United States, Canada and France. Jack Lawler's co-authors include Richard O. Hynes, Josephine C. Adams, Mark Duquette, Deane F. Mosher, Paul Börnstein, Patrick R. Lawler, Joanne E. Murphy-Ullrich, Azin Agah, Noël Bouck and Ben A. Barres and has published in prestigious journals such as New England Journal of Medicine, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Jack Lawler

206 papers receiving 19.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Thrombospondins Are Astrocyte-Secreted Proteins that Promote CNS Synaptogenesis

2005 1.3k citations Jack Lawler et al. profile →
Thrombospondin-1 Is a Major Activator of TGF-β1 In Vivo

1998 961 citations Susan E. Crawford, Veronica Stellmach et al. profile →
Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

2009 704 citations Jack Lawler et al. profile →
The structure of human thrombospondin, an adhesive glycoprotein with multiple calcium-binding sites and homologies with several different proteins.

1986 505 citations Jack Lawler, Richard O. Hynes profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jack Lawler United States	77	11.8k	4.7k	2.9k	2.6k	2.6k	206	20.2k
Patrìcia A. D'Amore United States	86	17.0k 1.4×	3.9k 0.8×	3.6k 1.3×	1.8k 0.7×	3.0k 1.2×	233	30.0k
M. Luisa Iruela‐Arispe United States	82	12.5k 1.1×	5.0k 1.1×	3.1k 1.1×	2.2k 0.9×	3.2k 1.2×	202	21.4k
Joseph A. Madri United States	85	8.6k 0.7×	3.6k 0.8×	2.2k 0.8×	5.5k 2.1×	2.9k 1.1×	241	21.0k
Bengt Westermark Sweden	86	16.4k 1.4×	4.2k 0.9×	5.4k 1.9×	2.6k 1.0×	4.0k 1.5×	340	29.1k
Paul Börnstein United States	93	13.8k 1.2×	5.4k 1.1×	2.6k 0.9×	4.8k 1.8×	4.2k 1.6×	277	27.2k
Hellmut G. Augustin Germany	79	11.0k 0.9×	3.4k 0.7×	4.3k 1.5×	1.3k 0.5×	2.0k 0.8×	206	19.0k
Lieve Moons Belgium	62	9.9k 0.8×	5.5k 1.2×	2.6k 0.9×	913 0.3×	1.6k 0.6×	270	19.5k
Marie‐Geneviève Mattéi France	95	15.9k 1.3×	2.4k 0.5×	3.6k 1.2×	1.7k 0.7×	2.6k 1.0×	507	29.2k
Deane F. Mosher United States	79	7.9k 0.7×	4.7k 1.0×	1.6k 0.6×	6.9k 2.6×	4.4k 1.7×	314	20.3k
Lena Claesson‐Welsh Sweden	87	22.2k 1.9×	5.8k 1.2×	6.9k 2.4×	3.5k 1.3×	4.8k 1.8×	256	32.3k

Countries citing papers authored by Jack Lawler

Since Specialization

Citations

This map shows the geographic impact of Jack Lawler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jack Lawler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jack Lawler more than expected).

Fields of papers citing papers by Jack Lawler

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jack Lawler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jack Lawler. The network helps show where Jack Lawler may publish in the future.

Co-authorship network of co-authors of Jack Lawler

This figure shows the co-authorship network connecting the top 25 collaborators of Jack Lawler. A scholar is included among the top collaborators of Jack Lawler based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jack Lawler. Jack Lawler is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

1.

Li, Stephanie, Peter M. Sadow, Mohammadreza Abbasian, et al.. (2023). The Tyrosine Kinase Inhibitor Lenvatinib Inhibits Anaplastic Thyroid Carcinoma Growth by Targeting Pericytes in the Tumor Microenvironment. Thyroid. 33(7). 835–848. 8 indexed citations

2.

Matuszewska, Kathy, et al.. (2021). Normalizing Tumor Vasculature to Reduce Hypoxia, Enhance Perfusion, and Optimize Therapy Uptake. Cancers. 13(17). 4444–4444. 65 indexed citations

3.

Matuszewska, Kathy, Lisa A. Santry, Jacob P. van Vloten, et al.. (2018). Combining Vascular Normalization with an Oncolytic Virus Enhances Immunotherapy in a Preclinical Model of Advanced-Stage Ovarian Cancer. Clinical Cancer Research. 25(5). 1624–1638. 60 indexed citations

4.

Prete, Alessandro, Agnes S. Lo, Peter M. Sadow, et al.. (2018). Pericytes Elicit Resistance to Vemurafenib and Sorafenib Therapy in Thyroid Carcinoma via the TSP-1/TGFβ1 Axis. Clinical Cancer Research. 24(23). 6078–6097. 46 indexed citations

5.

Sims, Jennifer N. & Jack Lawler. (2015). Thrombospondin-1-Based Antiangiogenic Therapy. Journal of Ocular Pharmacology and Therapeutics. 31(7). 366–370. 10 indexed citations

6.

Duquette, Mark, et al.. (2014). Thrombospondin-1 Modulates Actin Filament Remodeling and Cell Motility in Mouse Mammary Tumor cells in Vitro. PubMed. 2(4). e31–e31. 13 indexed citations

7.

Cursiefen, Claus, Kazuichi Maruyama, Felix Bock, et al.. (2011). Thrombospondin 1 inhibits inflammatory lymphangiogenesis by CD36 ligation on monocytes. The Journal of Experimental Medicine. 208(5). 1083–1092. 136 indexed citations

8.

Nucera, Carmelo, Alessandro Porrello, Zeus A. Antonello, et al.. (2010). B-Raf ^V600E and thrombospondin-1 promote thyroid cancer progression. Proceedings of the National Academy of Sciences. 107(23). 10649–10654. 149 indexed citations

9.

Ren, Bin, Keli Song, Sareh Parangi, et al.. (2009). A Double Hit to Kill Tumor and Endothelial Cells by TRAIL and Antiangiogenic 3TSR. Cancer Research. 69(9). 3856–3865. 44 indexed citations

10.

Tan, Kemin, Mark Duquette, Jin‐huan Liu, et al.. (2007). Heparin-induced cis- and trans-Dimerization Modes of the Thrombospondin-1 N-terminal Domain. Journal of Biological Chemistry. 283(7). 3932–3941. 29 indexed citations

11.

Sund, Malin, Yuki Hamano, Hikaru Sugimoto, et al.. (2005). Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressors. Proceedings of the National Academy of Sciences. 102(8). 2934–2939. 130 indexed citations

12.

Lawler, Jack. (2002). Thrombospondin‐1 as an endogenous inhibitor of angiogenesis and tumor growth. Journal of Cellular and Molecular Medicine. 6(1). 1–12. 433 indexed citations

13.

Lawler, Jack, Weimin Miao, Mark Duquette, et al.. (2001). Thrombospondin-1 Gene Expression Affects Survival and Tumor Spectrum of p53-Deficient Mice. American Journal Of Pathology. 159(5). 1949–1956. 89 indexed citations

14.

Guo, Ning, Vivian Zabrenetzky, Lakshmi Chandrasekaran, et al.. (1998). Differential roles of protein kinase C and pertussis toxin-sensitive G-binding proteins in modulation of melanoma cell proliferation and motility by thrombospondin 1.. PubMed. 58(14). 3154–62. 47 indexed citations

15.

Merle, Blandine, Luc Malaval, Jack Lawler, Pierre Delmas, & Philippe Clézardin. (1997). Decorin inhibits cell attachment to thrombospondin-1 by binding to a KKTR-dependent cell adhesive site present within the N-terminal domain of thrombospondin-1.. PubMed. 67(1). 75–83. 58 indexed citations

16.

Merle, Blandine, Luc Malaval, Jack Lawler, Pierre Delmas, & Philippe Clézardin. (1997). Decorin inhibits cell attachment to thrombospondin-1 by binding to a KKTR-dependent cell adhesive site present within the N-terminal domain of thrombospondin-1. Journal of Cellular Biochemistry. 67(1). 75–83. 47 indexed citations

17.

Pidard, Dominique, et al.. (1996). Proteolysis of thrombospondin during cathepsin‐G‐induced platelet aggregation: functional role of the 165‐kDa carboxy‐terminal fragment. FEBS Letters. 386(1). 82–86. 33 indexed citations

18.

Gasparini, Giulio, Douglas Hanahan, Gerhard Christofori, et al.. (1996). Basic and clinical research on angiogenesis. Vascular. 2401. 2412–2412. 1 indexed citations

19.

Adams, Josephine C. & Jack Lawler. (1994). Cell-type specific adhesive interactions of skeletal myoblasts with thrombospondin-1.. Molecular Biology of the Cell. 5(4). 423–437. 78 indexed citations

20.

Cohen, Amos, et al.. (1988). Identification of the protein 4.1 binding site to phosphatidylserine vesicles. Biochemistry. 27(2). 614–619. 79 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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