J. Alfredo Freites

6.8k total citations · 1 hit paper
67 papers, 5.3k citations indexed

About

J. Alfredo Freites is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Atomic and Molecular Physics, and Optics. According to data from OpenAlex, J. Alfredo Freites has authored 67 papers receiving a total of 5.3k indexed citations (citations by other indexed papers that have themselves been cited), including 56 papers in Molecular Biology, 13 papers in Cellular and Molecular Neuroscience and 11 papers in Atomic and Molecular Physics, and Optics. Recurrent topics in J. Alfredo Freites's work include Lipid Membrane Structure and Behavior (30 papers), Ion channel regulation and function (21 papers) and Protein Structure and Dynamics (17 papers). J. Alfredo Freites is often cited by papers focused on Lipid Membrane Structure and Behavior (30 papers), Ion channel regulation and function (21 papers) and Protein Structure and Dynamics (17 papers). J. Alfredo Freites collaborates with scholars based in United States, Germany and Ukraine. J. Alfredo Freites's co-authors include Douglas J. Tobias, Richard W. Pastor, Igor Vorobyov, Jeffery B. Klauda, Alexander D. MacKerell, Richard M. Venable, Stephen H. White, Gunnar von Heijne, Eric V. Schow and H. Ronald Kaback and has published in prestigious journals such as Nature, Chemical Reviews and Proceedings of the National Academy of Sciences.

In The Last Decade

J. Alfredo Freites

63 papers receiving 5.3k citations

Hit Papers

1 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types

2010 3.5k citations Jeffery B. Klauda, Richard M. Venable et al. The Journal of Physical Chemistry B profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
J. Alfredo Freites United States	24	4.4k	832	800	528	383	67	5.3k
Régis Pomès Canada	45	3.7k 0.9×	1.0k 1.2×	931 1.2×	620 1.2×	488 1.3×	107	5.5k
Vidyashankara Iyer United States	10	4.4k 1.0×	476 0.6×	647 0.8×	481 0.9×	385 1.0×	12	6.3k
Philip C. Biggin United Kingdom	43	4.7k 1.1×	463 0.6×	1.2k 1.5×	547 1.0×	592 1.5×	170	6.3k
Morten Ø. Jensen Denmark	31	3.5k 0.8×	776 0.9×	781 1.0×	1.1k 2.0×	429 1.1×	54	4.9k
Justin A. Lemkul United States	30	4.3k 1.0×	832 1.0×	425 0.5×	419 0.8×	428 1.1×	76	6.4k
Volkhard Helms Germany	41	4.2k 1.0×	757 0.9×	704 0.9×	393 0.7×	325 0.8×	219	5.8k
Daniel Lévy France	39	3.4k 0.8×	778 0.9×	530 0.7×	425 0.8×	240 0.6×	92	4.5k
Sergei Y. Noskov Canada	39	3.9k 0.9×	743 0.9×	988 1.2×	703 1.3×	756 2.0×	149	5.4k
Sarah Rauscher Canada	14	4.3k 1.0×	415 0.5×	437 0.5×	340 0.6×	472 1.2×	32	5.8k
Yuri N. Antonenko Russia	40	3.3k 0.8×	420 0.5×	773 1.0×	643 1.2×	365 1.0×	201	4.9k

Countries citing papers authored by J. Alfredo Freites

Since Specialization

Citations

This map shows the geographic impact of J. Alfredo Freites's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by J. Alfredo Freites with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites J. Alfredo Freites more than expected).

Fields of papers citing papers by J. Alfredo Freites

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by J. Alfredo Freites. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by J. Alfredo Freites. The network helps show where J. Alfredo Freites may publish in the future.

Co-authorship network of co-authors of J. Alfredo Freites

This figure shows the co-authorship network connecting the top 25 collaborators of J. Alfredo Freites. A scholar is included among the top collaborators of J. Alfredo Freites based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with J. Alfredo Freites. J. Alfredo Freites is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Freites, J. Alfredo, et al.. (2025). BPS2025 - Redox-responsive biomaterials: A synergistic approach to peptide self-assembly using molecular dynamics and experimental screening. Biophysical Journal. 124(3). 335a–335a.

Li, Chenghan, et al.. (2024). Quantitative insights into the mechanism of proton conduction and selectivity for the human voltage-gated proton channel Hv1. Proceedings of the National Academy of Sciences. 121(38). e2407479121–e2407479121.

Manville, Rían W., et al.. (2023). Native American ataxia medicines rescue ataxia-linked mutant potassium channel activity via binding to the voltage sensing domain. Nature Communications. 14(1). 3281–3281. 9 indexed citations

Kreutzer, Adam G., et al.. (2023). A β-barrel-like tetramer formed by a β-hairpin derived from Aβ. Chemical Science. 15(1). 285–297. 5 indexed citations

Hong, Liang, et al.. (2020). Voltage-dependent structural models of the human Hv1 proton channel from long-timescale molecular dynamics simulations. Proceedings of the National Academy of Sciences. 117(24). 13490–13498. 27 indexed citations

Lim, Victoria T., J. Alfredo Freites, Francesco Tombola, & Douglas J. Tobias. (2020). Thermodynamics and Mechanism of the Membrane Permeation of Hv1 Channel Blockers. The Journal of Membrane Biology. 254(1). 5–16. 7 indexed citations

Chen, Yuanyuan, Sara Capponi, Lu Zhu, et al.. (2017). YidC Insertase of Escherichia coli: Water Accessibility and Membrane Shaping. Structure. 25(9). 1403–1414.e3. 46 indexed citations

Ulmschneider, Martin B., Jakob P. Ulmschneider, J. Alfredo Freites, et al.. (2017). Transmembrane helices containing a charged arginine are thermodynamically stable. European Biophysics Journal. 46(7). 627–637. 19 indexed citations

Rankin, Blake M., et al.. (2015). Specific ion interactions with aromatic rings in aqueous solutions: Comparison of molecular dynamics simulations with a thermodynamic solute partitioning model and Raman spectroscopy. Chemical Physics Letters. 638. 1–8. 6 indexed citations

10.

Freites, J. Alfredo & Douglas J. Tobias. (2015). Voltage Sensing in Membranes: From Macroscopic Currents to Molecular Motions. The Journal of Membrane Biology. 248(3). 419–430. 15 indexed citations

11.

Kyrychenko, Alexander, J. Alfredo Freites, Jing He, et al.. (2014). Structural Plasticity in the Topology of the Membrane-Interacting Domain of HIV-1 gp41. Biophysical Journal. 106(3). 610–620. 23 indexed citations

12.

Andersson, Magnus, Ana‐Nicoleta Bondar, J. Alfredo Freites, et al.. (2012). Proton-Coupled Dynamics in Lactose Permease. Structure. 20(11). 1893–1904. 52 indexed citations

13.

Freites, J. Alfredo, Eric V. Schow, Stephen H. White, & Douglas J. Tobias. (2012). Microscopic Origin of Gating Current Fluctuations in a Potassium Channel Voltage Sensor. Biophysical Journal. 102(11). L44–L46. 21 indexed citations

14.

Freites, J. Alfredo, et al.. (2011). Separating Instability from Aggregation Propensity in γS-Crystallin Variants. Biophysical Journal. 100(2). 498–506. 64 indexed citations

15.

Klauda, Jeffery B., Richard M. Venable, J. Alfredo Freites, et al.. (2010). Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types. The Journal of Physical Chemistry B. 114(23). 7830–7843. 3536 indexed citations breakdown →

16.

Freites, J. Alfredo, et al.. (2010). Structure of a DOTAP Lipid Bilayer: A Concerted Neutron Scattering and Molecular Dynamics Study. Biophysical Journal. 98(3). 492a–492a. 1 indexed citations

17.

Schow, Eric V., J. Alfredo Freites, Andreas Bernsel, et al.. (2010). Arginine in Membranes: The Connection Between Molecular Dynamics Simulations and Translocon-Mediated Insertion Experiments. The Journal of Membrane Biology. 239(1-2). 35–48. 98 indexed citations

18.

Zhou, Yonggang, Lan Guan, J. Alfredo Freites, & H. Ronald Kaback. (2008). Opening and closing of the periplasmic gate in lactose permease. Proceedings of the National Academy of Sciences. 105(10). 3774–3778. 81 indexed citations

19.

Freites, J. Alfredo, Douglas J. Tobias, & Stephen H. White. (2006). A Voltage-Sensor Water Pore. Biophysical Journal. 91(11). L90–L92. 71 indexed citations

20.

Freites, J. Alfredo, Douglas J. Tobias, Gunnar von Heijne, & Stephen H. White. (2005). Interface connections of a transmembrane voltage sensor. Proceedings of the National Academy of Sciences. 102(42). 15059–15064. 186 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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