Istvan Botos

4.5k citations

48 papers · 3.4k indexed · 2 hit papers · h-index 27

Impact in

Immunology top 2%
- Immune Response and Inflammation
- interferon and immune responses
Microbiology top 1%
- Antimicrobial Peptides and Activities

Papers in ⓘ

Microbiology 5
- Antimicrobial Peptides and Activities 5
Genetics 18
- Bacterial Genetics and Biotechnology 17

Co-authors: David M. Segal (6 shared papers)David R. Davies (6 shared papers)Alexander Wlodawer (20 shared papers)Joseph Shiloach (4 shared papers)Lin Liu (2 shared papers)Yan Wang (1 shared paper)Joshua N. Leonard (1 shared paper)Susan K. Buchanan (11 shared papers)
Journals: Structure (4 papers)Journal of Molecular Biology (4 papers)Journal of Biological Chemistry (3 papers)Proceedings of the National Academy of Sciences (3 papers)Nature Communications (2 papers)
Partner nations: United States Russia France

In The Last Decade

Istvan Botos

46 papers receiving 3.4k citations

Hit Papers

align trajectories log scale

The Structural Biology of Toll-like Receptors 2011 · 506 citations

Peers

Countries citing papers authored by Istvan Botos

Since Specialization

Citations

This map shows the geographic impact of Istvan Botos's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Istvan Botos with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Istvan Botos more than expected).

Fields of papers citing papers by Istvan Botos

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Istvan Botos. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Istvan Botos. The network helps show where Istvan Botos may publish in the future.

Co-authors

The 25 scholars most cited alongside Istvan Botos, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Istvan Botos Line = papers co-authored together Istvan Botos links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 48 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA Science ·Lin Liu, Istvan Botos, Yan Wang, Joshua N. Leonard, Joseph Shiloach, David M. Segal, David R. Davies Hit paper breakdown →	2008	574
2	The Structural Biology of Toll-like Receptors Structure ·Istvan Botos, David M. Segal, David R. Davies Hit paper breakdown →	2011	506
3	The molecular structure of the Toll-like receptor 3 ligand-binding domain Proceedings of the National Academy of Sciences ·Jessica K. Bell, Istvan Botos, Pamela R. Hall, Janine Askins, Joseph Shiloach, David M. Segal, David R. Davies	2005	301
4	The Catalytic Domain of Escherichia coli Lon Protease Has a Unique Fold and a Ser-Lys Dyad in the Active Site Journal of Biological Chemistry ·Istvan Botos, Edward E. Melnikov, Scott Cherry, Joseph E. Tropea, Anna G. Khalatova, Fatima Rasulova, Zbigniew Dauter, Michael R. Maurizi, Т. В. Ротанова, Alexander Wlodawer, Alla Gustchina	2004	152
5	Structures of the Complexes of a Potent Anti-HIV Protein Cyanovirin-N and High Mannose Oligosaccharides Journal of Biological Chemistry ·Istvan Botos, Barry R. O’Keefe, Shilpa R. Shenoy, Laura K. Cartner, Daniel M. Ratner, Peter H. Seeberger, Michael R. Boyd, Alexander Wlodawer	2002	148
6	Structural insight into the role of the Ton complex in energy transduction Nature ·Hervé Celia, Nicholas Noinaj, Stanisłav D. Zakharov, Enrica Bordignon, Istvan Botos, Mónica Santamaría, Travis J. Barnard, William A. Cramer, Roland Lloubès, Susan K. Buchanan	2016	126
7	Structural and Functional Characterization of the LPS Transporter LptDE from Gram-Negative Pathogens Structure ·Istvan Botos, Nadim Majdalani, Stephen J. Mayclin, J.G. McCarthy, Karl Lundquist, Damian Wójtowicz, Travis J. Barnard, James C. Gumbart, Susan K. Buchanan	2016	113
8	Batimastat, a potent matrix mealloproteinase inhibitor, exhibits an unexpected mode of binding. Proceedings of the National Academy of Sciences ·Istvan Botos, Léonardo Scapozza, Daizhou Zhang, Lance A. Liotta, Erik Meyer	1996	113
9	Structural interaction of natural and synthetic inhibitors with the venom metalloproteinase, atrolysin C (form d). Proceedings of the National Academy of Sciences ·Daizhou Zhang, Istvan Botos, F. Xavier Gomis‐Rüth, Ronald J. Doll, C H Blood, F. George Njoroge, Jay W. Fox, Wolfram Bode, E. F. Meyer	1994	112
10	The Domain-Swapped Dimer of Cyanovirin-N Is in a Metastable Folded State Structure ·Laura G. Barrientos, John M. Louis, Istvan Botos, Toshiyuki Mori, Zhaozhong Han, Barry R. O’Keefe, Michael R. Boyd, Alexander Wlodawer, Angela M. Gronenborn	2002	105
11	The Toll-like receptor 3:dsRNA signaling complex Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms ·Istvan Botos, Lin Liu, Yan Wang, David M. Segal, David R. Davies	2009	80
12	Classification of ATP‐dependent proteases Lon and comparison of the active sites of their proteolytic domains European Journal of Biochemistry ·Т. В. Ротанова, Edward E. Melnikov, Anna G. Khalatova, O.V. Makhovskaya, Istvan Botos, Alexander Wlodawer, Alla Gustchina	2004	79
13	Proteins that bind high-mannose sugars of the HIV envelope Progress in Biophysics and Molecular Biology ·Istvan Botos, Alexander Wlodawer	2004	79
14	Slicing a protease: Structural features of the ATP‐dependent Lon proteases gleaned from investigations of isolated domains Protein Science ·Т. В. Ротанова, Istvan Botos, Edward E. Melnikov, Fatima Rasulova, Alla Gustchina, Michael R. Maurizi, Alexander Wlodawer	2006	73
15	Crystal structure of the AAA+ α domain of E. coli Lon protease at 1.9Å resolution Journal of Structural Biology ·Istvan Botos, Edward E. Melnikov, Scott Cherry, Anna G. Khalatova, Fatima Rasulova, Joseph E. Tropea, Michael R. Maurizi, Т. В. Ротанова, Alla Gustchina, Alexander Wlodawer	2003	69
16	Cryo-EM structure of the bacterial Ton motor subcomplex ExbB–ExbD provides information on structure and stoichiometry Communications Biology ·Hervé Celia, Istvan Botos, Xiaodan Ni, Tara Fox, Natalia de Val, Roland Lloubès, Jiansen Jiang, Susan K. Buchanan	2019	64
17	Structure and dynamics of a constitutively active neurotensin receptor Scientific Reports ·B. Krumm, Sangbae Lee, S. Bhattacharya, Istvan Botos, Courtney F. White, Haijuan Du, Nagarajan Vaidehi, Reinhard Grisshammer	2016	54
18	Cyanovirin-N: a sugar-binding antiviral protein with a new twist Cellular and Molecular Life Sciences ·Istvan Botos, Alexander Wlodawer	2003	54
19	The structure of an insect chymotrypsin Journal of Molecular Biology ·Istvan Botos, Erik Meyer, M. Nguyen, Stanley M. Swanson, John M. Koomen, David H. Russell, Edgar F. Meyer	2000	52
20	Structural insight into mitochondrial β-barrel outer membrane protein biogenesis Nature Communications ·Kathryn A. Diederichs, Xiaodan Ni, Sarah E. Rollauer, Istvan Botos, Xiao-Feng Tan, Martin King, Edmund R.S. Kunji, Jiansen Jiang, Susan K. Buchanan	2020	52

About Istvan Botos

Istvan Botos is a scholar working on Microbiology, Genetics, Virology, Molecular Medicine and Endocrinology, having authored 48 papers that have together received 3.4k indexed citations. Recurring topics across this work include Bacterial Genetics and Biotechnology (17 papers), RNA and protein synthesis mechanisms (14 papers), Enzyme Structure and Function (11 papers), Immune Response and Inflammation (6 papers), Carbohydrate Chemistry and Synthesis (5 papers), Antimicrobial Peptides and Activities (5 papers), Genomics and Phylogenetic Studies (4 papers) and Protein Structure and Dynamics (4 papers). The work is most often cited by research in Immunology (1.3k citations), Microbiology (348 citations), Virology (170 citations), Molecular Medicine (147 citations) and Molecular Biology (1.8k citations). Istvan Botos has collaborated with scholars based in United States, Russia and France. Frequent co-authors include David M. Segal, David R. Davies, Alexander Wlodawer, Joseph Shiloach, Lin Liu, Yan Wang, Joshua N. Leonard, Susan K. Buchanan, Alla Gustchina and Т. В. Ротанова. Their work appears in journals such as Structure, Journal of Molecular Biology, Journal of Biological Chemistry, Proceedings of the National Academy of Sciences and Nature Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact