Irwin Chen

2.5k citations

16 papers · 2.0k indexed · 1 hit paper · h-index 14

Impact in

Biophysics top 2%
Organic Chemistry top 5%
- Click Chemistry and Applications

Papers in ⓘ

Radiology, Nuclear Medicine and Imaging 6
- Monoclonal and Polyclonal Antibodies Research 6
Organic Chemistry 7
- Click Chemistry and Applications 4

Co-authors: Alice Y. Ting (6 shared papers)David R. Liu (3 shared papers)Brent M. Dorr (1 shared paper)Mark Howarth (1 shared paper)Weiying Lin (1 shared paper)Tyler J. Smart (1 shared paper)Tianyi Kou (1 shared paper)Bin Yao (1 shared paper)
Journals: Journal of the American Chemical Society (3 papers)Nature Methods (1 paper)Molecular Therapy (1 paper)Organic Letters (1 paper)Biotechnology and Bioengineering (1 paper)
Partner nations: United States Israel

In The Last Decade

Irwin Chen

16 papers receiving 2.0k citations

Hit Papers

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Site-specific labeling of cell surface proteins with biophysical probes using biotin ligase 2005 · 547 citations

Peers

Countries citing papers authored by Irwin Chen

Since Specialization

Citations

This map shows the geographic impact of Irwin Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Irwin Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Irwin Chen more than expected).

Fields of papers citing papers by Irwin Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Irwin Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Irwin Chen. The network helps show where Irwin Chen may publish in the future.

Co-authors

The 25 scholars most cited alongside Irwin Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Irwin Chen Line = papers co-authored together Irwin Chen links everyone, so they are left out of the graph.

All Works

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16 of 16 papers shown

#	Work
1	Site-specific labeling of cell surface proteins with biophysical probes using biotin ligase Nature Methods ·Irwin Chen, Mark Howarth, Weiying Lin, Alice Y. Ting Hit paper breakdown →	2005	547
2	A general strategy for the evolution of bond-forming enzymes using yeast display Proceedings of the National Academy of Sciences ·Irwin Chen, Brent M. Dorr, David R. Liu	2011	431
3	Theoretical and Experimental Insight into the Effect of Nitrogen Doping on Hydrogen Evolution Activity of Ni₃S₂ in Alkaline Medium Advanced Energy Materials ·Tianyi Kou, Tyler J. Smart, Bin Yao, Irwin Chen, David Thota, Yuan Ping, Yat Li	2018	266
4	Site-specific labeling of proteins with small molecules in live cells Current Opinion in Biotechnology ·Irwin Chen, Alice Y. Ting	2004	261
5	A De Novo Protein Binding Pair By Computational Design and Directed Evolution Molecular Cell ·John Karanicolas, Jacob E. Corn, Irwin Chen, Łukasz A. Joachimiak, Orly Dym, Sun H. Peck, Shira Albeck, Tamar Unger, Wenxin Hu, Gaohua Liu, Scott P Delbecq, G.T. Montelione, Clint P. Spiegel, David R. Liu, David Baker	2011	136
6	An Asymmetric Synthesis of Hamigeran B via a Pd Asymmetric Allylic Alkylation for Enantiodiscrimination Journal of the American Chemical Society ·Barry M. Trost, Carole Pissot‐Soldermann, Irwin Chen, Gretchen M. Schroeder	2004	78
7	Phage Display Evolution of a Peptide Substrate for Yeast Biotin Ligase and Application to Two-Color Quantum Dot Labeling of Cell Surface Proteins Journal of the American Chemical Society ·Irwin Chen, Yoon‐Aa Choi, Alice Y. Ting	2007	57
8	Expanding the Substrate Tolerance of Biotin Ligase through Exploration of Enzymes from Diverse Species Journal of the American Chemical Society ·Sarah A. Slavoff, Irwin Chen, Yoon‐Aa Choi, Alice Y. Ting	2008	55
9	Directed Evolution of a Small-Molecule-Triggered Intein with Improved Splicing Properties in Mammalian Cells Chemistry & Biology ·Sun H. Peck, Irwin Chen, David R. Liu	2011	53
10	A Short and Concise Asymmetric Synthesis of Hamigeran B Chemistry - A European Journal ·Barry M. Trost, Carole Pissot‐Soldermann, Irwin Chen	2004	44
11	Site-specific Modification of AAV Vector Particles With Biophysical Probes and Targeting Ligands Using Biotin Ligase Molecular Therapy ·Matthew D. Stachler, Irwin Chen, Alice Y. Ting, Jeffrey S. Bartlett	2008	40
12	On-chip background noise reduction for cell-based assays in droplets Lab on a Chip ·Pascaline Mary, Angela Chen, Irwin Chen, Adam R. Abate, David A. Weitz	2011	30
13	Nanoscale integration of single cell biologics discovery processes using optofluidic manipulation and monitoring Biotechnology and Bioengineering ·Marsela Jorgolli, Tanner Nevill, Aaron Winters, Irwin Chen, Su Kong Chong, Fen‐Fen Lin, Marissa Mock, Ching Chen, Kim Le, Christopher Tan, Philip Jess, Xu Han, Agi Hamburger, Jennitte Stevens, Trent P. Munro, Ming C. Wu, Philip Tagari, Les P. Miranda	2019	26
14	Generation of membrane proteins in polymer-based lipoparticles as flow cytometry antigens European Polymer Journal ·V. Mitch Luna, Mukta Vazir, Amit Vaish, Su Kong Chong, Irwin Chen, Harvey Yamane	2018	15
15	Synthesis of a Ketone Analogue of Biotin via the Intramolecular Pauson−Khand Reaction Organic Letters ·Eric McNeill, Irwin Chen, Alice Y. Ting	2006	6
16	Protocol for high-throughput cloning, expression, purification, and evaluation of bispecific antibodies STAR Protocols ·Danqing Li, Alexander C. Partin, Liangjun Zhao, Irwin Chen, Mark L. Michaels, Zhulun Wang, Fernando Garcés, Danyang Gong, Timothy P. Riley	2022	4

About Irwin Chen

Irwin Chen is a scholar working on Radiology, Nuclear Medicine and Imaging, Organic Chemistry, Molecular Biology, Cell Biology and Biotechnology, having authored 16 papers that have together received 2.0k indexed citations. Recurring topics across this work include Monoclonal and Polyclonal Antibodies Research (6 papers), Click Chemistry and Applications (4 papers), Biochemical and Structural Characterization (3 papers), RNA and protein synthesis mechanisms (3 papers), RNA Interference and Gene Delivery (3 papers), Chemical Synthesis and Analysis (3 papers), Glycosylation and Glycoproteins Research (2 papers) and Microfluidic and Capillary Electrophoresis Applications (2 papers). The work is most often cited by research in Biophysics (151 citations), Organic Chemistry (631 citations), Molecular Biology (1.3k citations), Radiology, Nuclear Medicine and Imaging (429 citations) and Cell Biology (265 citations). Irwin Chen has collaborated with scholars based in United States and Israel. Frequent co-authors include Alice Y. Ting, David R. Liu, Brent M. Dorr, Mark Howarth, Weiying Lin, Tyler J. Smart, Tianyi Kou, Bin Yao, Yuan Ping and Yat Li. Their work appears in journals such as Journal of the American Chemical Society, Nature Methods, Molecular Therapy, Organic Letters and Biotechnology and Bioengineering.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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