Irwin Chen

2.5k total citations · 1 hit paper
16 papers, 2.0k citations indexed

About

Irwin Chen is a scholar working on Molecular Biology, Organic Chemistry and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Irwin Chen has authored 16 papers receiving a total of 2.0k indexed citations (citations by other indexed papers that have themselves been cited), including 10 papers in Molecular Biology, 7 papers in Organic Chemistry and 6 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Irwin Chen's work include Monoclonal and Polyclonal Antibodies Research (6 papers), Click Chemistry and Applications (4 papers) and Chemical Synthesis and Analysis (3 papers). Irwin Chen is often cited by papers focused on Monoclonal and Polyclonal Antibodies Research (6 papers), Click Chemistry and Applications (4 papers) and Chemical Synthesis and Analysis (3 papers). Irwin Chen collaborates with scholars based in United States and Israel. Irwin Chen's co-authors include Alice Y. Ting, David R. Liu, Brent M. Dorr, Weiying Lin, Mark Howarth, Yat Li, Tyler J. Smart, Bin Yao, Yuan Ping and Tianyi Kou and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Molecular Cell.

In The Last Decade

Irwin Chen

16 papers receiving 2.0k citations

Hit Papers

Site-specific labeling of cell surface proteins with biop... 2005 2026 2012 2019 2005 100 200 300 400 500
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Site-specific labeling of cell surface proteins with biophysical probes using biotin ligase
    2005 547 citations Irwin Chen, Mark Howarth et al. Nature Methods profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Irwin Chen United States 14 1.3k 631 429 276 265 16 2.0k
Shinya Tsukiji Japan 29 2.0k 1.5× 1.1k 1.8× 503 1.2× 100 0.4× 414 1.6× 83 2.9k
Vu Hong United States 11 1.6k 1.2× 1.6k 2.5× 594 1.4× 157 0.6× 126 0.5× 11 2.5k
Arnaud Gautier France 28 2.1k 1.6× 955 1.5× 278 0.6× 57 0.2× 368 1.4× 67 3.2k
Jean‐Philippe Pellois United States 35 2.3k 1.7× 572 0.9× 242 0.6× 117 0.4× 94 0.4× 67 3.4k
Aimee L. Boyle Netherlands 23 1.6k 1.2× 344 0.5× 221 0.5× 66 0.2× 129 0.5× 56 2.3k
Tione Buranda United States 27 844 0.7× 166 0.3× 129 0.3× 138 0.5× 238 0.9× 67 1.8k
Anouk Dirksen Netherlands 22 1.6k 1.3× 1.3k 2.1× 545 1.3× 106 0.4× 154 0.6× 34 2.7k
Timothy R. Chan United States 6 1.9k 1.4× 2.2k 3.5× 570 1.3× 218 0.8× 116 0.4× 6 2.9k
Luo Sun United States 17 1.0k 0.8× 212 0.3× 140 0.3× 67 0.2× 132 0.5× 38 1.5k
Nathan W. Luedtke Switzerland 36 3.1k 2.4× 1.1k 1.8× 190 0.4× 92 0.3× 67 0.3× 92 3.7k

Countries citing papers authored by Irwin Chen

Since Specialization
Citations

This map shows the geographic impact of Irwin Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Irwin Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Irwin Chen more than expected).

Fields of papers citing papers by Irwin Chen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Irwin Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Irwin Chen. The network helps show where Irwin Chen may publish in the future.

Co-authorship network of co-authors of Irwin Chen

This figure shows the co-authorship network connecting the top 25 collaborators of Irwin Chen. A scholar is included among the top collaborators of Irwin Chen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Irwin Chen. Irwin Chen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

16 of 16 papers shown
1.
Li, Danqing, Liangjun Zhao, Irwin Chen, et al.. (2022). Protocol for high-throughput cloning, expression, purification, and evaluation of bispecific antibodies. STAR Protocols. 3(2). 101428–101428. 4 indexed citations
2.
Jorgolli, Marsela, Aaron Winters, Irwin Chen, et al.. (2019). Nanoscale integration of single cell biologics discovery processes using optofluidic manipulation and monitoring. Biotechnology and Bioengineering. 116(9). 2393–2411. 26 indexed citations
3.
Vaish, Amit, et al.. (2018). Generation of membrane proteins in polymer-based lipoparticles as flow cytometry antigens. European Polymer Journal. 109. 483–488. 15 indexed citations
4.
Kou, Tianyi, Tyler J. Smart, Bin Yao, et al.. (2018). Theoretical and Experimental Insight into the Effect of Nitrogen Doping on Hydrogen Evolution Activity of Ni3S2 in Alkaline Medium. Advanced Energy Materials. 8(19). 266 indexed citations
5.
Chen, Irwin, Brent M. Dorr, & David R. Liu. (2011). A general strategy for the evolution of bond-forming enzymes using yeast display. Proceedings of the National Academy of Sciences. 108(28). 11399–11404. 431 indexed citations
6.
Karanicolas, John, Jacob E. Corn, Irwin Chen, et al.. (2011). A De Novo Protein Binding Pair By Computational Design and Directed Evolution. Molecular Cell. 42(2). 250–260. 136 indexed citations
7.
Peck, Sun H., Irwin Chen, & David R. Liu. (2011). Directed Evolution of a Small-Molecule-Triggered Intein with Improved Splicing Properties in Mammalian Cells. Chemistry & Biology. 18(5). 619–630. 53 indexed citations
8.
Mary, Pascaline, Angela Chen, Irwin Chen, Adam R. Abate, & David A. Weitz. (2011). On-chip background noise reduction for cell-based assays in droplets. Lab on a Chip. 11(12). 2066–2066. 30 indexed citations
9.
Stachler, Matthew D., Irwin Chen, Alice Y. Ting, & Jeffrey S. Bartlett. (2008). Site-specific Modification of AAV Vector Particles With Biophysical Probes and Targeting Ligands Using Biotin Ligase. Molecular Therapy. 16(8). 1467–1473. 40 indexed citations
10.
Slavoff, Sarah A., Irwin Chen, Yoon‐Aa Choi, & Alice Y. Ting. (2008). Expanding the Substrate Tolerance of Biotin Ligase through Exploration of Enzymes from Diverse Species. Journal of the American Chemical Society. 130(4). 1160–1162. 55 indexed citations
11.
Chen, Irwin, Yoon‐Aa Choi, & Alice Y. Ting. (2007). Phage Display Evolution of a Peptide Substrate for Yeast Biotin Ligase and Application to Two-Color Quantum Dot Labeling of Cell Surface Proteins. Journal of the American Chemical Society. 129(20). 6619–6625. 57 indexed citations
12.
McNeill, Eric, Irwin Chen, & Alice Y. Ting. (2006). Synthesis of a Ketone Analogue of Biotin via the Intramolecular Pauson−Khand Reaction. Organic Letters. 8(20). 4593–4595. 6 indexed citations
13.
Chen, Irwin, Mark Howarth, Weiying Lin, & Alice Y. Ting. (2005). Site-specific labeling of cell surface proteins with biophysical probes using biotin ligase. Nature Methods. 2(2). 99–104. 547 indexed citations breakdown →
14.
Chen, Irwin & Alice Y. Ting. (2004). Site-specific labeling of proteins with small molecules in live cells. Current Opinion in Biotechnology. 16(1). 35–40. 261 indexed citations
15.
Trost, Barry M., Carole Pissot‐Soldermann, Irwin Chen, & Gretchen M. Schroeder. (2004). An Asymmetric Synthesis of Hamigeran B via a Pd Asymmetric Allylic Alkylation for Enantiodiscrimination. Journal of the American Chemical Society. 126(14). 4480–4481. 78 indexed citations
16.
Trost, Barry M., Carole Pissot‐Soldermann, & Irwin Chen. (2004). A Short and Concise Asymmetric Synthesis of Hamigeran B. Chemistry - A European Journal. 11(3). 951–959. 44 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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