Ira Pastan

4.9k total citations
71 papers, 4.2k citations indexed

About

Ira Pastan is a scholar working on Immunology, Biotechnology and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Ira Pastan has authored 71 papers receiving a total of 4.2k indexed citations (citations by other indexed papers that have themselves been cited), including 58 papers in Immunology, 36 papers in Biotechnology and 33 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Ira Pastan's work include Toxin Mechanisms and Immunotoxins (53 papers), Monoclonal and Polyclonal Antibodies Research (33 papers) and Transgenic Plants and Applications (32 papers). Ira Pastan is often cited by papers focused on Toxin Mechanisms and Immunotoxins (53 papers), Monoclonal and Polyclonal Antibodies Research (33 papers) and Transgenic Plants and Applications (32 papers). Ira Pastan collaborates with scholars based in United States, United Kingdom and Canada. Ira Pastan's co-authors include Ulrich Brinkmann, Vijay K. Chaudhary, D J FitzGerald, Johannes Büchner, David J. FitzGerald, Mark C. Willingham, Nancy Richert, Robert J. Kreitman, Lee H. Pai and M C Willingham and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Ira Pastan

69 papers receiving 4.0k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Ira Pastan United States	34	2.2k	1.9k	1.5k	1.3k	942	71	4.2k
Arthur E. Frankel United States	40	2.5k 1.2×	2.6k 1.4×	509 0.3×	1.3k 1.0×	1.4k 1.5×	144	5.2k
Richard P. Junghans United States	41	2.4k 1.1×	2.0k 1.0×	1.7k 1.2×	314 0.2×	2.4k 2.5×	99	5.7k
Arthur E. Frankel United States	35	1.6k 0.7×	1.4k 0.8×	490 0.3×	731 0.6×	854 0.9×	107	3.4k
Inka Brockhausen Canada	39	2.0k 0.9×	4.7k 2.5×	829 0.6×	438 0.3×	407 0.4×	144	5.4k
Janendra K. Batra India	25	825 0.4×	1.2k 0.7×	521 0.4×	498 0.4×	496 0.5×	88	2.3k
M. J. Embleton United Kingdom	30	1.1k 0.5×	1.4k 0.7×	1.3k 0.9×	227 0.2×	806 0.9×	82	2.8k
Roy Jefferis United Kingdom	36	2.3k 1.0×	4.4k 2.3×	4.0k 2.7×	549 0.4×	401 0.4×	113	6.1k
Albert B. DeLeo United States	44	4.5k 2.1×	3.3k 1.8×	589 0.4×	684 0.5×	3.2k 3.4×	119	7.7k
William D. Huse United States	17	690 0.3×	2.3k 1.2×	1.3k 0.9×	218 0.2×	347 0.4×	25	3.4k
Tapan K. Bera United States	34	1.0k 0.5×	1.5k 0.8×	356 0.2×	466 0.4×	1.0k 1.1×	87	3.6k

Countries citing papers authored by Ira Pastan

Since Specialization

Citations

This map shows the geographic impact of Ira Pastan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ira Pastan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ira Pastan more than expected).

Fields of papers citing papers by Ira Pastan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ira Pastan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ira Pastan. The network helps show where Ira Pastan may publish in the future.

Co-authorship network of co-authors of Ira Pastan

This figure shows the co-authorship network connecting the top 25 collaborators of Ira Pastan. A scholar is included among the top collaborators of Ira Pastan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ira Pastan. Ira Pastan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Onda, Masanori, Xiufen Liu, Wenlong Liu, et al.. (2025). RO4, a high-affinity humanized antibody against the juxtamembrane region of mesothelin for targeted cancer therapy. PubMed. 9(1). 1–12.

Peer, Cody J., Xianyu Zhang, Hyoyoung Choo‐Wosoba, et al.. (2024). Tofacitinib to prevent anti-drug antibody formation against LMB-100 immunotoxin in patients with advanced mesothelin-expressing cancers. Frontiers in Oncology. 14. 1386190–1386190. 3 indexed citations

Hollevoet, Kevin, Antonella Antignani, David J. FitzGerald, & Ira Pastan. (2013). Combining the Antimesothelin Immunotoxin SS1P With the BH3-mimetic ABT-737 Induces Cell Death in SS1P-resistant Pancreatic Cancer Cells. Journal of Immunotherapy. 37(1). 8–15. 15 indexed citations

Hafkemeyer, Peter, Thomas Licht, Ira Pastan, & Michael M. Gottesman. (2000). Chemoprotection of Hematopoietic Cells by a Mutant P-Glycoprotein Resistant to a Potent Chemosensitizer of Multidrug-Resistant Cancers. Human Gene Therapy. 11(4). 555–565. 13 indexed citations

Viner, Jaye L., et al.. (1999). Pharmacokinetics and antitumor activity of a bivalent disulfide-stabilized Fv immunotoxin with improved antigen binding to erbB2.. PubMed. 59(16). 4018–22. 33 indexed citations

Pai-Scherf, Lee H., et al.. (1999). Hepatotoxicity in cancer patients receiving erb-38, a recombinant immunotoxin that targets the erbB2 receptor.. PubMed. 5(9). 2311–5. 89 indexed citations

Kobayashi, Hisataka, In‐Sook Kim, Nhat Le, et al.. (1998). Similarities in the Biodistribution of Iodine-Labeled Anti-Tac Single-Chain Disulfide-Stabilized Fv Fragment and Anti-Tac Disulfide-Stabilized Fv Fragment. Nuclear Medicine and Biology. 25(4). 387–393. 9 indexed citations

Fischer, Paul H., et al.. (1996). The performance of e23(Fv)PEs, recombinant toxins targeting the erbB-2 protein. Seminars in Cancer Biology. 7(2). 79–86. 15 indexed citations

Pastan, Ira, et al.. (1995). Recombinant Toxins: New Therapeutic Agents for Cancer. Annals of the New York Academy of Sciences. 758(1). 345–354. 38 indexed citations

10.

Mesri, Enrique A., Minoru Ōno, Robert J. Kreitman, Michael Klagsbrun, & Ira Pastan. (1994). The heparin-binding domain of heparin-binding EGF-like growth factor can target Pseudomonas exotoxin to kill cells exclusively through heparan sulfate proteoglycans. Journal of Cell Science. 107(9). 2599–2608. 15 indexed citations

11.

Choe, Moran, Keith O. Webber, & Ira Pastan. (1994). B3(Fab)-PE38M: a recombinant immunotoxin in which a mutant form of Pseudomonas exotoxin is fused to the Fab fragment of monoclonal antibody B3.. PubMed. 54(13). 3460–7. 14 indexed citations

12.

Chin, Khew‐Voon, Irene Abraham, Kathleen E. Sampson, et al.. (1992). Reduced mRNA levels for the multidrug‐resistance genes in cAMP‐dependent protein kinase mutant cell lines. Journal of Cellular Physiology. 152(1). 87–94. 28 indexed citations

13.

Theuer, Charles P., David FitzGerald, & Ira Pastan. (1992). A recombinant form of Pseudomonas exotoxin directed at the epidermal growth factor receptor that is cytotoxic without requiring proteolytic processing.. Journal of Biological Chemistry. 267(24). 16872–16877. 36 indexed citations

14.

Pai, Lee H., Janendra K. Batra, David J. FitzGerald, Mark C. Willingham, & Ira Pastan. (1991). Anti-tumor activities of immunotoxins made of monoclonal antibody B3 and various forms of Pseudomonas exotoxin.. Proceedings of the National Academy of Sciences. 88(8). 3358–3362. 59 indexed citations

15.

Batra, Janendra K., Vijay K. Chaudhary, David FitzGerald, & Ira Pastan. (1990). TGFα-anti-Tac(Fv)-PE40: A bifunctional toxin cytotoxic for cells with EGF or IL2 receptors. Biochemical and Biophysical Research Communications. 171(1). 1–6. 14 indexed citations

16.

Goldstein, Lori J., M M Gottesman, Ira Pastan, et al.. (1989). MDR1 Gene Expression in Lung Cancer. JNCI Journal of the National Cancer Institute. 81(15). 1144–1150. 164 indexed citations

17.

Richert, Nancy, Lois Aldwin, Danute E. Nitecki, Michael M. Gottesman, & Ira Pastan. (1988). Stability and covalent modification of P-glycoprotein in multidrug-resistant KB cells. Biochemistry. 27(20). 7607–7613. 113 indexed citations

18.

FitzGerald, D J, et al.. (1988). Activity of immunotoxins constructed with modified Pseudomonas exotoxin A lacking the cell recognition domain.. Journal of Biological Chemistry. 263(19). 9470–9475. 129 indexed citations

19.

Beguinot, Laura, John A. Hanover, Seiji Ito, et al.. (1985). Phorbol esters induce transient internalization without degradation of unoccupied epidermal growth factor receptors.. Proceedings of the National Academy of Sciences. 82(9). 2774–2778. 180 indexed citations

20.

Xu, Y H, Nancy Richert, Seiji Ito, Glenn Merlino, & Ira Pastan. (1984). Characterization of epidermal growth factor receptor gene expression in malignant and normal human cell lines.. Proceedings of the National Academy of Sciences. 81(23). 7308–7312. 206 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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