Ikuo Hirano

28.1k total citations · 9 hit papers
285 papers, 11.8k citations indexed

About

Ikuo Hirano is a scholar working on Surgery, Rheumatology and Gastroenterology. According to data from OpenAlex, Ikuo Hirano has authored 285 papers receiving a total of 11.8k indexed citations (citations by other indexed papers that have themselves been cited), including 263 papers in Surgery, 117 papers in Rheumatology and 46 papers in Gastroenterology. Recurrent topics in Ikuo Hirano's work include Eosinophilic Esophagitis (247 papers), Eosinophilic Disorders and Syndromes (116 papers) and Esophageal and GI Pathology (48 papers). Ikuo Hirano is often cited by papers focused on Eosinophilic Esophagitis (247 papers), Eosinophilic Disorders and Syndromes (116 papers) and Esophageal and GI Pathology (48 papers). Ikuo Hirano collaborates with scholars based in United States, Switzerland and Netherlands. Ikuo Hirano's co-authors include Nirmala Gonsalves, Evan S. Dellon, Raj K. Goyal, John E. Pandolfino, Peter J. Kahrilas, Glenn T. Furuta, David A. Katzka, Chris A. Liacouras, Joel E. Richter and Bethany Doerfler and has published in prestigious journals such as New England Journal of Medicine, The Lancet and JAMA.

In The Last Decade

Ikuo Hirano

271 papers receiving 11.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

ACG Clinical Guideline: Evidenced Based Approach to the Diagnosis and Management of Esophageal Eosinophilia and Eosinophilic Esophagitis (EoE)

2013 827 citations Evan S. Dellon, Nirmala Gonsalves et al. The American Journal of Gastroenterology profile →
Long-term Outcome of Medical and Surgical Therapies for Gastroesophageal Reflux Disease

2001 648 citations Ikuo Hirano et al. profile →
Endoscopic assessment of the oesophageal features of eosinophilic oesophagitis: validation of a novel classification and grading system

2012 620 citations Ikuo Hirano, Nirmala Gonsalves et al. Gut profile →
The Enteric Nervous System

1996 568 citations Ikuo Hirano et al. New England Journal of Medicine profile →
Epidemiology and Natural History of Eosinophilic Esophagitis

2017 522 citations Evan S. Dellon, Ikuo Hirano Gastroenterology profile →
Elimination Diet Effectively Treats Eosinophilic Esophagitis in Adults; Food Reintroduction Identifies Causative Factors

2012 443 citations Nirmala Gonsalves, Guang‐Yu Yang et al. Gastroenterology profile →
American Gastroenterological Association Institute Guideline on Therapeutic Drug Monitoring in Inflammatory Bowel Disease

2017 411 citations Ikuo Hirano et al. Gastroenterology profile →
Eosinophil Depletion with Benralizumab for Eosinophilic Esophagitis

2024 34 citations Marc E. Rothenberg, Evan S. Dellon et al. New England Journal of Medicine profile →
ACG Clinical Guideline: Diagnosis and Management of Eosinophilic Esophagitis

2025 26 citations Evan S. Dellon, David A. Katzka et al. The American Journal of Gastroenterology profile →

Peers

Countries citing papers authored by Ikuo Hirano

Since Specialization

Citations

This map shows the geographic impact of Ikuo Hirano's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ikuo Hirano with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ikuo Hirano more than expected).

Fields of papers citing papers by Ikuo Hirano

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ikuo Hirano. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ikuo Hirano. The network helps show where Ikuo Hirano may publish in the future.

Co-authorship network of co-authors of Ikuo Hirano

This figure shows the co-authorship network connecting the top 25 collaborators of Ikuo Hirano. A scholar is included among the top collaborators of Ikuo Hirano based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ikuo Hirano. Ikuo Hirano is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Review article: Seeing Is Believing–The Eosinophilic Oesophagitis Endoscopic Reference Score Can Serve as a Valuable Clinical Trial Endpoint in Eosinophilic Oesophagitis 2025 ·Alimentary Pharmacology & Therapeutics ·Ikuo Hirano, Glenn T. Furuta, Gary W. Falk, Christopher Ma, Nirmala Gonsalves, Evan S. Dellon	0
2	Dupilumab Improves Histopathologic Features in Patients With Eosinophilic Esophagitis: LIBERTY EoE TREET Study Results 2025 ·Gastro Hep Advances ·Margaret H. Collins, Marc E. Rothenberg, Evan S. Dellon, Albert J. Bredenoord, Ikuo Hirano, John Leung, Xian Sun, Lila Glotfelty, Arsalan Shabbir	0
3	Design of a phase 3, randomized, double-blind, placebo-controlled, 48-week study to evaluate the efficacy and safety of cendakimab in adult and adolescent patients with eosinophilic esophagitis 2024 ·Contemporary Clinical Trials ·(unknown), (unknown), (unknown), (unknown), Young S. Oh, Ikuo Hirano, (unknown), Evan S. Dellon	2
4	Eosinophil Depletion with Benralizumab for Eosinophilic Esophagitis breakdown → 2024 ·New England Journal of Medicine ·Marc E. Rothenberg, Evan S. Dellon, Margaret H. Collins, Albert J. Bredenoord, Ikuo Hirano, Kathryn A. Peterson, Laura Brooks, Julie M. Caldwell, (unknown), Hanna Grindebacke, (unknown), (unknown), Christopher McCrae, Dominic Sinibaldi, Wendy I. White, Catherine Datto	34
5	The Minimally Invasive 1-Hour Esophageal String Test Monitors Therapeutic Changes in Mucosal Inflammation in Eosinophilic Esophagitis 2024 ·The American Journal of Gastroenterology ·Steven J. Ackerman, Amir F. Kagalwalla, Zhaoxing Pan, Joshua B. Wechsler, (unknown), Nirmala Gonsalves, Ikuo Hirano, Angelika Zalewski, Paul Menard‐Katcher, Calies Menard‐Katcher, Sandeep Kumar Gupta, Nikhil Chauhan, Milica Grozdanović, Dan Atkins, Nathalie Nguyen, Glenn T. Furuta	1
6	Sa1275 IMPROVEMENTS IN HISTOLOGIC, SYMPTOMATIC, AND ENDOSCOPIC ASPECTS OF EOSINOPHILIC ESOPHAGITIS ARE MAINTAINED, OR CONTINUE TO IMPROVE, WITH LONG-TERM DUPILUMAB TREATMENT, REGARDLESS OF PRIOR ESOPHAGEAL DILATION 2024 ·Gastroenterology ·Albert J. Bredenoord, Evan S. Dellon, Ikuo Hirano, Changming Xia, Elizabeth Laws, Michael C. Nivens, Raolat M. Abdulai, Jennifer Maloney, Lila Glotfelty, Arsalan Shabbir	1
7	A PhysioMechanical Model of Esophageal Function in Eosinophilic Esophagitis 2023 ·Gastroenterology ·Dustin A. Carlson, Ikuo Hirano, Nirmala Gonsalves, Peter J. Kahrilas, Isis K. Araujo, Mi-Ra Yang, Marie‐Pier Tétreault, John E. Pandolfino	27
8	Measuring esophageal compliance using functional lumen imaging probe to assess remodeling in eosinophilic esophagitis 2023 ·Neurogastroenterology & Motility ·(unknown), (unknown), Wenjun Kou, Ikuo Hirano, Nirmala Gonsalves, (unknown), John E. Pandolfino, Dustin A. Carlson	14
9	Prospective study of an amino acid–based elemental diet in an eosinophilic gastritis and gastroenteritis nutrition trial 2023 ·Journal of Allergy and Clinical Immunology ·Nirmala Gonsalves, Bethany Doerfler, Angelika Zalewski, Guang‐Yu Yang, Lisa J. Martin, Xue Zhang, Tetsuo Shoda, Michael Brusilovsky, Seema S. Aceves, (unknown), Amanda K. Rudman Spergel, Glenn T. Furuta, Marc E. Rothenberg, Ikuo Hirano	19
10	Bulk T‐cell receptor sequencing confirms clonality in pediatric eosinophilic esophagitis and identifies a food‐specific repertoire 2023 ·Allergy ·(unknown), Fei Li Kuang, Angelika Zalewski, Katie Amsden, Mingyu Wang, (unknown), (unknown), Ikuo Hirano, Amir F. Kagalwalla, Barry K. Wershil, Nirmala Gonsalves, Joshua B. Wechsler	3
11	Tapinarof validates the aryl hydrocarbon receptor as a therapeutic target: A clinical review 2023 ·Journal of Allergy and Clinical Immunology ·Jonathan I. Silverberg, Mark Boguniewicz, Francisco J. Quintana, Rachael A. Clark, (unknown), Ikuo Hirano, Anna M. Tallman, Philip M. Brown, Doral Fredericks, David S. Rubenstein, (unknown)	44
12	610 EFFICACY AND SAFETY OF BENRALIZUMAB IN ADULTS AND ADOLESCENTS WITH EOSINOPHILIC ESOPHAGITIS: RESULTS FROM THE 24-WEEK DOUBLE-BLIND PERIOD OF THE PHASE 3 MESSINA TRIAL 2023 ·Gastroenterology ·Marc E. Rothenberg, Evan S. Dellon, Margaret H. Collins, Albert J. Bredenoord, Ikuo Hirano, Kathryn A. Peterson, Laura Brooks, (unknown), Hanna Grindebacke, (unknown), (unknown), Christopher McCrae, Wendy White, Catherine Datto	8
13	Comparing the relative efficacy of therapeutics for eosinophilic oesophagitis: is counting eosinophils the right target? 2023 ·Gut ·Ikuo Hirano, David A. Katzka	1
14	Epidemiology and implications of concurrent diagnosis of eosinophilic oesophagitis and IBD based on a prospective population-based analysis 2019 ·Gut ·Berkeley N. Limketkai, Shailja C. Shah, Ikuo Hirano, Emanuelle Bellaguarda, Jean‐Frédéric Colombel	48
15	Summary of the updated international consensus diagnostic criteria for eosinophilic esophagitis 2018 ·Annals of Allergy Asthma & Immunology ·Jonathan M. Spergel, Evan S. Dellon, Chris A. Liacouras, Ikuo Hirano, Javier Molina‐Infante, Albert J. Bredenoord, Glenn T. Furuta	59
16	Budesonide Oral Suspension Improves Symptomatic, Endoscopic, and Histologic Parameters Compared With Placebo in Patients With Eosinophilic Esophagitis 2017 ·Carolina Digital Repository (University of North Carolina at Chapel Hill) ·Evan S. Dellon, David A. Katzka, Margaret H. Collins, Mohamed Hamdani, Sandeep K. Gupta, Ikuo Hirano	1
17	T-Helper 2 Cytokines, Transforming Growth Factor β1, and Eosinophil Products Induce Fibrogenesis and Alter Muscle Motility in Patients With Eosinophilic Esophagitis 2014 ·Gastroenterology ·Florian Rieder, (unknown), Jie Ma, Zhufeng Ouyang, Gail West, Cheryl Protheroe, Giovanni De Petris, Anja Schirbel, (unknown), John R. Goldblum, Tracey L. Bonfield, Rocío López, Karen M. Harnett, James Lee, Ikuo Hirano, Gary W. Falk, Piero Biancani, Claudio Fiocchi	117
18	Eosinophilic esophagitis: are we just scratching the surface? 2013 ·PubMed Central ·Meena Prasad, Ikuo Hirano	2
19	Elimination Diet Effectively Treats Eosinophilic Esophagitis in Adults; Food Reintroduction Identifies Causative Factors breakdown → 2012 ·Gastroenterology ·Nirmala Gonsalves, Guang‐Yu Yang, Bethany Doerfler, Sally Ritz, Anne M. Ditto, Ikuo Hirano	443
20	Acid Reflux Detection and Symptom-Reflux Association Using 4-Day Wireless pH Recording Combining 48-Hour Periods Off and On PPI Therapy 2008 ·The American Journal of Gastroenterology ·(unknown), Qing Zhang, Nirmala Gonsalves, Ikuo Hirano	20

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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