Hugo Fraga

1.5k total citations
34 papers, 1.1k citations indexed

About

Hugo Fraga is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Materials Chemistry. According to data from OpenAlex, Hugo Fraga has authored 34 papers receiving a total of 1.1k indexed citations (citations by other indexed papers that have themselves been cited), including 30 papers in Molecular Biology, 11 papers in Cellular and Molecular Neuroscience and 5 papers in Materials Chemistry. Recurrent topics in Hugo Fraga's work include Photoreceptor and optogenetics research (11 papers), bioluminescence and chemiluminescence research (10 papers) and Protein Structure and Dynamics (7 papers). Hugo Fraga is often cited by papers focused on Photoreceptor and optogenetics research (11 papers), bioluminescence and chemiluminescence research (10 papers) and Protein Structure and Dynamics (7 papers). Hugo Fraga collaborates with scholars based in Portugal, Spain and France. Hugo Fraga's co-authors include Rui Fontes, Joaquim C. G. Esteves da Silva, Alfred L. Goldberg, Diogo Fernandes, Galit Kafri, David M. Smith, Christian Robson de Souza Reis, Lerna Uzasci, Bruce R. Branchini and Martha H. Murtiashaw and has published in prestigious journals such as Cell, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Hugo Fraga

34 papers receiving 1.1k citations

Peers

Hugo Fraga

CMN

BIOPH

Poncho Meisenheimer United States

Alois Sonnleitner Austria

Feng He United States

Donghui Zhang China

Randal B. Bass United States

Tapas K. Mal Canada

Ivan Gushchin Russia

Dora Toledo Warshaviak United States

David Salom United States

Ricardo Capone United States

Poncho Meisenheimer United States

Hugo Fraga

1.4k ×1.5

306 ×1.0

CMN

391 ×2.1

194 ×1.4

BIOPH

35 ×0.3

Citations per year, relative to Hugo Fraga Hugo Fraga (= 1×) peers Poncho Meisenheimer

Countries citing papers authored by Hugo Fraga

Since Specialization

Citations

This map shows the geographic impact of Hugo Fraga's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hugo Fraga with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hugo Fraga more than expected).

Fields of papers citing papers by Hugo Fraga

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hugo Fraga. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hugo Fraga. The network helps show where Hugo Fraga may publish in the future.

Co-authorship network of co-authors of Hugo Fraga

This figure shows the co-authorship network connecting the top 25 collaborators of Hugo Fraga. A scholar is included among the top collaborators of Hugo Fraga based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hugo Fraga. Hugo Fraga is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Weinhäupl, Katharina, Sandy Desrat, Catherine Guillou, et al.. (2025). Identification of new ClpC1-NTD binders for Mycobacterium tuberculosis drug development. Scientific Reports. 15(1). 4146–4146. 1 indexed citations

Arnaud, Charles‐Adrien, et al.. (2024). Deuteration of proteins boosted by cell lysates: high-resolution amide and H α magic-angle-spinning (MAS) NMR without the reprotonation bottleneck. SHILAP Revista de lepidopterología. 5(1). 33–49. 2 indexed citations

Weinhäupl, Katharina, Marcos Gragera, Rocío Arranz, et al.. (2022). Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. Journal of Biological Chemistry. 298(11). 102553–102553. 15 indexed citations

Gauto, Diego F., Pavel Macek, Alessandro Barducci, et al.. (2019). Aromatic Ring Dynamics, Thermal Activation, and Transient Conformations of a 468 kDa Enzyme by Specific ¹ H– ¹³ C Labeling and Fast Magic-Angle Spinning NMR. Journal of the American Chemical Society. 141(28). 11183–11195. 37 indexed citations

Weinhäupl, Katharina, Martha Brennich, Uli Kazmaier, et al.. (2018). The antibiotic cyclomarin blocks arginine-phosphate–induced millisecond dynamics in the N-terminal domain of ClpC1 from Mycobacterium tuberculosis. Journal of Biological Chemistry. 293(22). 8379–8393. 33 indexed citations

Fraga, Hugo, Ana I. Bardera, Tatos Akopian, et al.. (2018). Development of high throughput screening methods for inhibitors of ClpC1P1P2 from Mycobacteria tuberculosis. Analytical Biochemistry. 567. 30–37. 16 indexed citations

Fraga, Hugo, Jordi Pujols, Alicia Roque, et al.. (2017). Disulfide driven folding for a conditionally disordered protein. Scientific Reports. 7(1). 16994–16994. 16 indexed citations

Fraga, Hugo, et al.. (2015). Intradomain Confinement of Disulfides in the Folding of Two Consecutive Modules of the LDL Receptor. PLoS ONE. 10(7). e0132141–e0132141. 3 indexed citations

Fraga, Hugo & Salvador Ventura. (2015). Influence of Cytoplasmatic Folding on Mitochondrial Import. Current Medicinal Chemistry. 22(19). 2349–2359. 3 indexed citations

10.

Fraga, Hugo & Salvador Ventura. (2012). Protein Oxidative Folding in the Intermembrane Mitochondrial Space: More than Protein Trafficking. Current Protein and Peptide Science. 13(3). 224–231. 5 indexed citations

11.

Fraga, Hugo, Elena Papaleo, Sonia Vega, Adrián Velázquez‐Campoy, & Salvador Ventura. (2012). Zinc induced folding is essential for TIM15 activity as an mtHsp70 chaperone. Biochimica et Biophysica Acta (BBA) - General Subjects. 1830(1). 2139–2149. 10 indexed citations

12.

Smith, David M., Hugo Fraga, Christian Robson de Souza Reis, Galit Kafri, & Alfred L. Goldberg. (2011). ATP Binds to Proteasomal ATPases in Pairs with Distinct Functional Effects, Implying an Ordered Reaction Cycle. Cell. 144(4). 526–538. 158 indexed citations

13.

Fraga, Hugo & Rui Fontes. (2011). Enzymatic synthesis of mono and dinucleoside polyphosphates. Biochimica et Biophysica Acta (BBA) - General Subjects. 1810(12). 1195–1204. 29 indexed citations

14.

Fraga, Hugo. (2008). Firefly luminescence: A historical perspective and recent developments. Photochemical & Photobiological Sciences. 7(2). 146–158. 158 indexed citations

15.

Fontes, Rui, et al.. (2008). Pyrophosphate and tripolyphosphate affect firefly luciferase luminescence because they act as substrates and not as allosteric effectors. FEBS Journal. 275(7). 1500–1509. 35 indexed citations

16.

Fraga, Hugo, Diogo Fernandes, Jiří Novotný, Rui Fontes, & Joaquim C. G. Esteves da Silva. (2006). Firefly Luciferase Produces Hydrogen Peroxide as a Coproduct in Dehydroluciferyl Adenylate Formation. ChemBioChem. 7(6). 929–935. 49 indexed citations

17.

Fraga, Hugo, Diogo Fernandes, Rui Fontes, & Joaquim C. G. Esteves da Silva. (2005). Coenzyme A affects firefly luciferase luminescence because it acts as a substrate and not as an allosteric effector. FEBS Journal. 272(20). 5206–5216. 69 indexed citations

18.

Fraga, Hugo, Rui Fontes, & Joaquim C. G. Esteves da Silva. (2005). Synthesis of Luciferyl Coenzyme A: A Bioluminescent Substrate for Firefly Luciferase in the Presence of AMP. Angewandte Chemie International Edition. 44(22). 3427–3429. 10 indexed citations

19.

Fraga, Hugo, Joaquim C. G. Esteves da Silva, & Rui Fontes. (2003). Identification of Luciferyl Adenylate and Luciferyl Coenzyme A Synthesized by Firefly Luciferase. ChemBioChem. 5(1). 110–115. 35 indexed citations

20.

Fraga, Hugo, Joaquim C. G. Esteves da Silva, & Rui Fontes. (2003). pH opposite effects on synthesis of dinucleoside polyphosphates and on oxidation reactions catalyzed by firefly luciferase. FEBS Letters. 543(1-3). 37–41. 16 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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