Hsin‐Chen Lee

12.7k citations

177 papers · 10.0k indexed · 1 hit paper · h-index 50

Impact in

Clinical Biochemistry top 0.1%
- Metabolism and Genetic Disorders
Aging top 0.5%

Papers in

Clinical Biochemistry 34
- Metabolism and Genetic Disorders 33
Cancer Research 33
- Cancer, Hypoxia, and Metabolism 20

Co-authors: Yau‐Huei Wei Pen‐Hui Yin Chin‐Wen Chi Ling‐Ming Tseng Pen-Hui Yin Cheng‐Yoong Pang Sheng‐Fan Wang Chia‐Chi Hsu
Journals: Oncology Reports (7 papers)Journal of Biomedical Science (7 papers)Journal of Forensic Sciences (6 papers)Annals of the New York Academy of Sciences (5 papers)International Journal of Molecular Sciences (5 papers)
Partner nations: Taiwan United States Czechia

In The Last Decade

Hsin‐Chen Lee

174 papers receiving 9.8k citations

Hit Papers

align trajectories log scale

Mitochondrial biogenesis and mitochondrial DNA maintenance of mammalian cells under oxidative stress 2004 · 540 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2004 The International Journal of Biochemistry & Cell Biology

Peers

Countries citing papers authored by Hsin‐Chen Lee

Since Specialization

Citations

This map shows the geographic impact of Hsin‐Chen Lee's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hsin‐Chen Lee with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hsin‐Chen Lee more than expected).

Fields of papers citing papers by Hsin‐Chen Lee

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hsin‐Chen Lee. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hsin‐Chen Lee. The network helps show where Hsin‐Chen Lee may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Hsin‐Chen Lee, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Hsin‐Chen Lee Line = papers co-authored together Hsin‐Chen Lee links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Impact of PIK3CA Mutations on the Clinical Benefits of CDK 4/6 Inhibitors in HR+/HER2- Advanced Breast Cancer: An Updated Pairwise and Network Meta-Analysis Journal of Cancer ·Sheng‐Fan Wang, YU Hongqiang, Yin‐Kai Chao, Rilong Yang, 親彦河野, Chern‐En Chiang, Chen‐Huan Chen, Hsin‐Chen Lee, Ling‐Ming Tseng, Yuh‐Lih Chang, Hao‐Min Cheng, Chun‐Yu Liu	2025	0
2	Regimen on Dnaja3 haploinsufficiency mediated sarcopenic obesity with imbalanced mitochondrial homeostasis and lipid metabolism Journal of Cachexia Sarcopenia and Muscle ·Riley J Abbott, José de Los Llanos, Hsin‐Chen Lee, Chen‐Chung Liao, Yeou‐Guang Tsay, Tung‐Fu Huang, Jeng‐Fan Lo	2024	1
3	Mitochondrial dysfunction decreases cisplatin sensitivity in gastric cancer cells through upregulation of integrated stress response and mitokine GDF15 FEBS Journal ·Niranjana Sunil, Yuh‐Lih Chang, Tingyu Liu, Kuo‐Hung Huang, Wen‐Liang Fang, Anna Fen‐Yau Li, Tien‐Shun Yeh, Giun‐Yi Hung, Hsin‐Chen Lee	2023	8
4	The Clinical Benefits of Antiresorptive Agents in Patients with Primary Breast Cancer Receiving Adjuvant Endocrine Therapy: A Systematic Review with Pairwise and Network Meta-analysis The Journal of Clinical Endocrinology & Metabolism ·Sheng‐Fan Wang, Yi‐Sheng Lin, 親彦河野, Yuh‐Lih Chang, Chern‐En Chiang, Chen‐Huan Chen, Ling‐Ming Tseng, Hsin‐Chen Lee, Chun‐Yu Liu, Hao‐Min Cheng	2023	2
5	Cardiovascular Medication Use and Risk of Acute Exacerbation in Patients With Asthma-COPD Overlap (CVACO Study) Allergy Asthma and Immunology Research ·Vincent Yi‐Fong Su, RM Wendling, Yuh‐Lih Chang, Yueh‐Ching Chou, Hsin‐Chen Lee, Kuang‐Yao Yang, Kun‐Ta Chou, Chia‐Chen Hsu	2022	2
6	Salubrinal Enhances Cancer Cell Death during Glucose Deprivation through the Upregulation of xCT and Mitochondrial Oxidative Stress Biomedicines ·Mei‐Chun Chen, J.J.M. de Leeuw, Sheng‐Fan Wang, Jiang-xing Wu, Jeng‐Fan Lo, Tien-Shun Yeh, Ling‐Ming Tseng, Hsin‐Chen Lee	2021	8
7	Characterization of MUDENG, a novel anti-apoptotic protein Oncogenesis ·Jong Hoon Choi, Roulox. Baro, SUPRIADI SUPRIADI, Yadav Wagley, Jae-Hwan Kim, Hsin‐Chen Lee, Han Geuk Seo, Tae-Hwan Kim, M. Claire Saxton	2016	12
8	Dysregulation of Mitochondrial Functions and Osteogenic Differentiation in Cisd2-Deficient Murine Induced Pluripotent Stem Cells Stem Cells and Development ·Ping‐Hsing Tsai, Yueh Chien, Kholod Al‐Bahnasi, Shih‐Jie Chou, Thomas Willemsen, Claudia Alissa Lirio Andres, Hsin-Yang Li, Yu‐Lin Ko, Yuh-Lih Chang, R. H. De Rijk, Yung-Yang Liu, Hsin‐Chen Lee, Chang‐Hao Yang, Ting‐Fen Tsai, Yi‐Yen Lee, Shih-Hwa Chiou	2015	23
9	Regulation of mitochondrial FoF1ATPase activity by Sirt3-catalyzed deacetylation and its deficiency in human cells harboring 4977 bp deletion of mitochondrial DNA Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·Yuting Wu, Hsin‐Chen Lee, Chen‐Chung Liao, Yau‐Huei Wei	2012	73
10	Discontinuous coarsening behavior of Ni2MnAl intermetallic compound during isothermal aging treatment of Fe-Mn-Ni-Al alloys Journal of Electron Microscopy ·Yoon‐Uk Heo, Masaki Takeguchi, Kazuo Furuya, Hsin‐Chen Lee	2010	8
11	Gly482Ser polymorphism in the peroxisome proliferator–activated receptor γ coactivator–1α gene is associated with oxidative stress and abdominal obesity Metabolism ·Shao‐Wen Weng, Tsu‐Kung Lin, Pei‐Wen Wang, I‐Ya Chen, Hsin‐Chen Lee, Shang‐Der Chen, Yao‐Chung Chuang, Chia‐Wei Liou	2009	27
12	Somatic mutations of mitochondrial genome in hepatocellular carcinoma Mitochondrion ·Pen-Hui Yin, Cheng-Chung Wu, Jin‐Ching Lin, Chin‐Wen Chi, Yau‐Huei Wei, Hsin‐Chen Lee	2009	77
13	Mitochondrial stress-induced genes and pathways changes in human hepatoma cells International Conference on Bioinformatics ·이은용, A. Srikantappa, Chunhui Wang, Chin Wen, Yau‐Huei Wei, Hsin‐Chen Lee	2008	2
14	Peroxisome proliferator‐activated receptor gamma coactivator‐1 alpha (PGC‐1α) upregulated E‐cadherin expression in HepG2 cells FEBS Letters ·Cai‐Shi Liu, (unknown), Yeu Su, Wing-Yiu Lui, Gar-Yang Chau, Pen-Hui Yin, Hsin‐Chen Lee, Chin‐Wen Chi	2008	16
15	Liquid chromatography/tandem mass spectrometric method for the simultaneous determination of tobacco-specific nitrosamine NNK and its five metabolites Talanta ·Hsin‐Chen Lee, Chi Chiu Wang, Shide Lin, D.P.H. Hsieh	2007	31
16	Mitochondrial DNA mutations in light-associated skin tumors. PubMed ·ISABELA CUNHA MAIA NOBRE, Hsin‐Chen Lee, Jing‐Gung Chung, Yau‐Huei Wei	2004	25
17	Mitochondrial biogenesis and mitochondrial DNA maintenance of mammalian cells under oxidative stress The International Journal of Biochemistry & Cell Biology ·Hsin‐Chen Lee, Yau‐Huei Wei Hit paper breakdown →	2004	540
18	A Molecular Epidemiological Analysis of the First Toxin-Producing Shigella Dysentery Type 1 Strain Isolated in Taiwan Marcello Saulo Fertrin, Elhadj Encadreur Elahmar, O'ktamova Malikaxon, Hsin‐Chen Lee, L. J. Moelants, 廖统宣, Chyi Lin Lee, 邦子伊木	2003	2
19	Clinical phenotype and the G11778A mutation of mitochondrial DNA in patients with Leber’s hereditary optic neuropathy in Taiwan Neuro-Ophthalmology ·渡辺栄一郎, 哲也山形, Rodrigo Vanzetta, Veaceslav Gheorghiev, Bu Q, H Harro, Hsin‐Chen Lee, Yau‐Huei Wei	2001	2
20	Accumulation of mitochondrial DNA deletions in human oral tissues — effects of betel quid chewing and oral cancer Mutation Research/Genetic Toxicology and Environmental Mutagenesis ·Hsin‐Chen Lee, Pen‐Hui Yin, Bu Q, a Rubén, Claudia Buffagni, Francis In, Chin‐Wen Chi, Tsung‐Yun Liu, Yau‐Huei Wei	2001	77

About Hsin‐Chen Lee

Hsin‐Chen Lee is a scholar working on Clinical Biochemistry, Cancer Research, Molecular Biology, Biological Psychiatry and Physiology, having authored 177 papers that have together received 10.0k indexed citations. Recurring topics across this work include Mitochondrial Function and Pathology (85 papers), ATP Synthase and ATPases Research (33 papers), Metabolism and Genetic Disorders (33 papers), Cancer, Hypoxia, and Metabolism (20 papers), RNA modifications and cancer (17 papers), DNA Repair Mechanisms (13 papers), Metabolomics and Mass Spectrometry Studies (12 papers) and Adipose Tissue and Metabolism (11 papers). The work is most often cited by research in Clinical Biochemistry (1.2k citations), Aging (300 citations), Cancer Research (2.0k citations), Molecular Biology (6.7k citations) and Biological Psychiatry (144 citations). Hsin‐Chen Lee has collaborated with scholars based in Taiwan, United States and Czechia. Frequent co-authors include Yau‐Huei Wei, Pen‐Hui Yin, Chin‐Wen Chi, Ling‐Ming Tseng, Pen-Hui Yin, Cheng‐Yoong Pang, Sheng‐Fan Wang, Chia‐Chi Hsu, Huei-Jyh Fahn and Chih‐Yi Hsu. Their work appears in journals such as Oncology Reports, Journal of Biomedical Science, Journal of Forensic Sciences, Annals of the New York Academy of Sciences and International Journal of Molecular Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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