Hiroshi Tokumitsu

7.2k total citations · 2 hit papers
117 papers, 6.1k citations indexed

About

Hiroshi Tokumitsu is a scholar working on Molecular Biology, Cell Biology and Surgery. According to data from OpenAlex, Hiroshi Tokumitsu has authored 117 papers receiving a total of 6.1k indexed citations (citations by other indexed papers that have themselves been cited), including 100 papers in Molecular Biology, 19 papers in Cell Biology and 12 papers in Surgery. Recurrent topics in Hiroshi Tokumitsu's work include Protein Kinase Regulation and GTPase Signaling (42 papers), S100 Proteins and Annexins (26 papers) and Metabolism, Diabetes, and Cancer (17 papers). Hiroshi Tokumitsu is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (42 papers), S100 Proteins and Annexins (26 papers) and Metabolism, Diabetes, and Cancer (17 papers). Hiroshi Tokumitsu collaborates with scholars based in Japan, United States and Canada. Hiroshi Tokumitsu's co-authors include Thomas R. Soderling, Ryōji Kobayashi, Gary A. Wayman, Shigetoshi Yano, Akihiro Mizutani, Hisashi Hidaka, Hervé Enslen, Masatoshi Hagiwara, Motomu Terasawa and Takashi Chijiwa and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Hiroshi Tokumitsu

115 papers receiving 6.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

KN-62, 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazi ne, a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II.

1990 582 citations Hiroshi Tokumitsu, Masatoshi Hagiwara et al. Journal of Biological Chemistry profile →
Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway

1998 534 citations Shigetoshi Yano, Hiroshi Tokumitsu et al. Nature profile →

Peers

Countries citing papers authored by Hiroshi Tokumitsu

Since Specialization

Citations

This map shows the geographic impact of Hiroshi Tokumitsu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hiroshi Tokumitsu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hiroshi Tokumitsu more than expected).

Fields of papers citing papers by Hiroshi Tokumitsu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hiroshi Tokumitsu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hiroshi Tokumitsu. The network helps show where Hiroshi Tokumitsu may publish in the future.

Co-authorship network of co-authors of Hiroshi Tokumitsu

This figure shows the co-authorship network connecting the top 25 collaborators of Hiroshi Tokumitsu. A scholar is included among the top collaborators of Hiroshi Tokumitsu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hiroshi Tokumitsu. Hiroshi Tokumitsu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Development of a novel AAK1 inhibitor via Kinobeads-based screening 2024 ·Scientific Reports ·Akari Yoshida, (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), Masaki Magari, Naoya Hatano, Ryo Morishita, Ayano Satoh, Yukinari Sunatsuki, Ulf J. Nilsson, Teruhiko Ishikawa, Hiroshi Tokumitsu	1
2	Transcriptional, biochemical, and immunohistochemical analyses of CaMKKβ/2 splice variants that co-localize with CaMKIV in spermatids 2023 ·Cell Calcium ·(unknown), Yumi Miyai, Hiroyuki Mima, Masaki Magari, Yoichi Chiba, Futoshi Suizu, Hiroyuki Sakagami, Masaki Ueno, Hiroshi Tokumitsu	0
3	PHI-1, an Endogenous Inhibitor Protein for Protein Phosphatase-1 and a Pan-Cancer Marker, Regulates Raf-1 Proteostasis 2023 ·Biomolecules ·(unknown), (unknown), (unknown), Kosuke Takeya, Yoshinori Tanaka, Hiroshi Tokumitsu, Futoshi Suizu, Masumi Eto	1
4	Substrate recognition by Arg/Pro‐rich insert domain in calcium/calmodulin‐dependent protein kinase kinase for target protein kinases 2022 ·FEBS Journal ·(unknown), (unknown), (unknown), (unknown), Masaki Magari, Naoki Kanayama, Naoya Hatano, Hiroyuki Sakagami, Hiroshi Tokumitsu	6
5	Phosphorylation and dephosphorylation of Ca2+/calmodulin-dependent protein kinase kinase β at Thr144 in HeLa cells 2020 ·Biochemical and Biophysical Research Communications ·(unknown), (unknown), (unknown), Naoki Kanayama, Masaki Magari, Hiroyuki Sakagami, Naoya Hatano, Hiroshi Tokumitsu	2
6	Compartmentalized AMPK Signaling Illuminated by Genetically Encoded Molecular Sensors and Actuators 2015 ·Cell Reports ·Takafumi Miyamoto, (unknown), Vedangi Sample, (unknown), Masaki Magari, Tasuku Ueno, Kirill Gorshkov, Melinda Chen, Hiroshi Tokumitsu, Jin Zhang, Takanari Inoue	82
7	Oxidized S100A4 inhibits the activation of protein phosphatase 5 through S100A1 in MKN-45 gastric carcinoma cells 2014 ·International Journal of Molecular Medicine ·(unknown), Fuminori Yamaguchi, Seiko Shimamoto, (unknown), Hiroshi Tokumitsu, Masaaki Tokuda, Ryōji Kobayashi	7
8	In vitro substrate phosphorylation by Ca2+/calmodulin-dependent protein kinase kinase using guanosine-5′-triphosphate as a phosphate donor 2012 ·BMC Biochemistry ·(unknown), (unknown), Masaki Magari, Naoki Kanayama, Ryōji Kobayashi, Hiroshi Tokumitsu	2
9	Inactivation of Ca²⁺/calmodulin‐dependent protein kinase I by S‐glutathionylation of the active‐site cysteine residue 2010 ·FEBS Letters ·Toshie Kambe, Tao Song, Tsuyoshi Takata, Naoya Hatano, Yoshiaki Miyamoto, Naohito Nozaki, Yasuhito Naito, Hiroshi Tokumitsu, Yasuo Watanabe	24
10	Exendin‐4 regulates glucokinase expression by CaMKK/CaMKIV pathway in pancreatic β‐cell line 2009 ·Diabetes Obesity and Metabolism ·Koji Murao, (unknown), Hitomi Imachi, (unknown), Hisashi Masugata, (unknown), Ryōji Kobayashi, Toshihiko Ishida, Hiroshi Tokumitsu	32
11	Interactions of S100A2 and S100A6 with the Tetratricopeptide Repeat Proteins, Hsp90/Hsp70-organizing Protein and Kinesin Light Chain 2008 ·Journal of Biological Chemistry ·Seiko Shimamoto, (unknown), Masaaki Tokuda, (unknown), Hiroshi Tokumitsu, Ryōji Kobayashi	43
12	Spatiotemporal expression of four isoforms of Ca2+/calmodulin-dependent protein kinase I in brain and its possible roles in hippocampal dendritic growth 2006 ·Neuroscience Research ·(unknown), Hiroyuki Sakagami, Hiroshi Tokumitsu, Yuji Owada, Kohji Fukunaga, Hisatake Kondo	26
13	Mechanism of the Generation of Autonomous Activity of Ca2+/Calmodulin-dependent Protein Kinase IV 2004 ·Journal of Biological Chemistry ·Hiroshi Tokumitsu, Naoya Hatano, Hiroyuki Inuzuka, (unknown), Naohito Nozaki, Ryōji Kobayashi	47
14	Transcriptional regulation of nuclear orphan receptor, NOR‐1, by Ca²⁺/calmodulin‐dependent protein kinase cascade 2002 ·FEBS Letters ·Hiroyuki Inuzuka, Hiroshi Tokumitsu, Naganari Ohkura, Ryōji Kobayashi	12
15	STO-609, a Specific Inhibitor of the Ca2+/Calmodulin-dependent Protein Kinase Kinase 2002 ·Journal of Biological Chemistry ·Hiroshi Tokumitsu, Hiroyuki Inuzuka, Yumi Ishikawa, Masahiko Ikeda, Ikutaro Saji, Ryōji Kobayashi	245
16	Interaction of S100 Proteins with the Antiallergic Drugs, Olopatadine, Amlexanox, and Cromolyn: Identification of Putative Drug Binding Sites on S100A1 Protein 2002 ·Biochemical and Biophysical Research Communications ·Miki Okada, Hiroshi Tokumitsu, Yasuo Kubota, Ryōji Kobayashi	39
17	Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway breakdown → 1998 ·Nature ·Shigetoshi Yano, Hiroshi Tokumitsu, Thomas R. Soderling	534
18	NFATx, a Novel Member of the Nuclear Factor of Activated T Cells Family That Is Expressed Predominantly in the Thymus 1995 ·Molecular and Cellular Biology ·Esteban S. Masuda, Yoshiyuki Naito, Hiroshi Tokumitsu, (unknown), Fumiko Saito, Charles Hannum, Ken-ichi Arai, Naoko Arai	196
19	Purification and characterization of 81K, heat stable calmodulin-binding protein from bovine brain 1989 ·Biochemical and Biophysical Research Communications ·Hiroshi Tokumitsu, Akihiro Mizutani, Seiji Nomura, Masato Watanabe, Hiroyoshi Hidaka	6
20	Monoclonal Antibody Assessment of Tissue- and Species-Specific Myosin Light Chain Kinase Isozymes1 1989 ·The Journal of Biochemistry ·Masatoshi Hagiwara, Hiroshi Tokumitsu, Koji Onoda, Toshio Tanaka, Masaaki Ito, Nobuo Kato, Hiroyoshi Hidaka	7

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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