Hiroko Otake

988 total citations
58 papers, 749 citations indexed

About

Hiroko Otake is a scholar working on Pharmaceutical Science, Public Health, Environmental and Occupational Health and Ophthalmology. According to data from OpenAlex, Hiroko Otake has authored 58 papers receiving a total of 749 indexed citations (citations by other indexed papers that have themselves been cited), including 26 papers in Pharmaceutical Science, 19 papers in Public Health, Environmental and Occupational Health and 18 papers in Ophthalmology. Recurrent topics in Hiroko Otake's work include Ocular Surface and Contact Lens (19 papers), Advanced Drug Delivery Systems (18 papers) and Advancements in Transdermal Drug Delivery (13 papers). Hiroko Otake is often cited by papers focused on Ocular Surface and Contact Lens (19 papers), Advanced Drug Delivery Systems (18 papers) and Advancements in Transdermal Drug Delivery (13 papers). Hiroko Otake collaborates with scholars based in Japan, India and Saudi Arabia. Hiroko Otake's co-authors include Noriaki Nagai, Fumihiko Ogata, Naohito Kawasaki, Yosuke Nakazawa, Naoki Yamamoto, Noriko Hiramatsu, Norio Okamoto, Hiroshi Sasaki, Tomoyuki Okuda and K. Kánai and has published in prestigious journals such as PLoS ONE, Advanced Drug Delivery Reviews and International Journal of Molecular Sciences.

In The Last Decade

Hiroko Otake

52 papers receiving 737 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Hiroko Otake Japan 17 309 208 207 123 121 58 749
Sinar Sayed Egypt 16 513 1.7× 164 0.8× 216 1.0× 76 0.6× 123 1.0× 20 829
Sadek Ahmed Egypt 15 324 1.0× 112 0.5× 152 0.7× 71 0.6× 101 0.8× 29 755
Jayamanti Pandit India 12 492 1.6× 211 1.0× 150 0.7× 92 0.7× 103 0.9× 20 792
Joana Araújo Spain 7 609 2.0× 239 1.1× 222 1.1× 75 0.6× 88 0.7× 9 838
Dongzhi Hou China 13 513 1.7× 238 1.1× 202 1.0× 70 0.6× 102 0.8× 24 847
Yanzhong Chen China 14 321 1.0× 128 0.6× 215 1.0× 81 0.7× 87 0.7× 28 587
Hanan Refai Egypt 15 660 2.1× 198 1.0× 199 1.0× 48 0.4× 55 0.5× 23 983
Miguel González‐Barcia Spain 20 258 0.8× 188 0.9× 191 0.9× 214 1.7× 286 2.4× 67 1.0k
Nurşen Ünlü Türkiye 14 319 1.0× 145 0.7× 232 1.1× 152 1.2× 125 1.0× 16 625
Aditya Konar India 16 63 0.2× 212 1.0× 155 0.7× 149 1.2× 104 0.9× 31 756

Countries citing papers authored by Hiroko Otake

Since Specialization
Citations

This map shows the geographic impact of Hiroko Otake's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hiroko Otake with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hiroko Otake more than expected).

Fields of papers citing papers by Hiroko Otake

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hiroko Otake. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hiroko Otake. The network helps show where Hiroko Otake may publish in the future.

Co-authorship network of co-authors of Hiroko Otake

This figure shows the co-authorship network connecting the top 25 collaborators of Hiroko Otake. A scholar is included among the top collaborators of Hiroko Otake based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hiroko Otake. Hiroko Otake is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Otake, Hiroko, et al.. (2025). Dermal formulation based on carbopol and Gum Arabic improves skin retention of indomethacin. PLoS ONE. 20(6). e0326051–e0326051.
2.
Kobayakawa, Shinichiro, Toru Matsunaga, Hiroko Otake, et al.. (2025). Solid Tranilast Nanocrystal-Loaded Cationic Contact Lenses for Sustained Ocular Drug Delivery. Pharmaceutics. 17(10). 1240–1240.
3.
Matsunaga, Toru, Fumihiko Ogata, Hiroko Otake, et al.. (2025). Design of Tranilast-Loaded Cation-Type Contact Lens for Sustainable Ocular Drug Delivery. Pharmaceutics. 17(6). 712–712. 1 indexed citations
4.
Otake, Hiroko, et al.. (2024). Copolymerized Polymers Based on Cyclodextrins and Cationic Groups Enhance Therapeutic Effect of Rebamipide in the N-Acetylcysteine-Treated Dry Eye Model. Drug Design Development and Therapy. Volume 18. 4345–4358. 1 indexed citations
5.
Otake, Hiroko, Fumihiko Ogata, Yosuke Nakazawa, et al.. (2024). Therapeutic Effects of Rebamipide Nanocrystals as Carbopol Gel Formulation Containing Gum Arabic in a Hamster Model of Oral Mucositis. Journal of Oleo Science. 73(12). 1479–1491. 2 indexed citations
6.
Otake, Hiroko, Tetsushi Yamamoto, Yoshiki Miyata, et al.. (2024). Semiquantitative analysis of protein expression in heated rat lens using shotgun proteomics. Molecular Medicine Reports. 31(1).
7.
Otake, Hiroko, et al.. (2024). Enhancement of therapeutic efficacy of Brinzolamide for Glaucoma by nanocrystallization and tyloxapol addition. Journal of Pharmaceutical Health Care and Sciences. 10(1). 55–55. 3 indexed citations
8.
Nagai, Noriaki, Fumihiko Ogata, Hiroko Otake, et al.. (2023). Orally disintegrating tablets containing famotidine nanoparticles provide high intestinal absorbability via the energy-dependent endocytosis pathway. Frontiers in Bioengineering and Biotechnology. 11. 1167291–1167291. 3 indexed citations
9.
Ogata, Fumihiko, M. Nishida, Hiroko Otake, et al.. (2023). Therapeutic Effects of Hydrogel Formulations Incorporating Troxipide Nanoparticles on Oral Mucositis in Hamsters. Drug Design Development and Therapy. Volume 17. 3349–3361. 3 indexed citations
10.
Otake, Hiroko, et al.. (2023). Effect of Ointment Base on the Skin Wound-Healing Deficits in Streptozotocin-Induced Diabetic Rat. Biological and Pharmaceutical Bulletin. 46(5). 707–712. 2 indexed citations
11.
Ogata, Fumihiko, et al.. (2023). Nasal Absorption Enhancement of Mometasone Furoate Nanocrystal Dispersions. International Journal of Nanomedicine. Volume 18. 5685–5699. 8 indexed citations
12.
Nagai, Noriaki, Fumihiko Ogata, Hiroko Otake, & Naohito Kawasaki. (2020). Oral Administration System Based on Meloxicam Nanocrystals: Decreased Dose Due to High Bioavailability Attenuates Risk of Gastrointestinal Side Effects. Pharmaceutics. 12(4). 313–313. 17 indexed citations
13.
Nagai, Noriaki, et al.. (2020). An in situ Gelling System Based on Methylcellulose and Tranilast Solid Nanoparticles Enhances Ocular Residence Time and Drug Absorption Into the Cornea and Conjunctiva. Frontiers in Bioengineering and Biotechnology. 8. 764–764. 29 indexed citations
14.
Nagai, Noriaki, et al.. (2019). Changes in mitochondrial cytochrome c oxidase mRNA levels with cataract severity in lens epithelia of Japanese patients. Molecular Medicine Reports. 19(6). 5464–5472. 4 indexed citations
15.
Nagai, Noriaki, et al.. (2019). Combination with l-Menthol Enhances Transdermal Penetration of Indomethacin Solid Nanoparticles. International Journal of Molecular Sciences. 20(15). 3644–3644. 21 indexed citations
16.
Nagai, Noriaki, Fumihiko Ogata, Hiroko Otake, Yosuke Nakazawa, & Naohito Kawasaki. (2019). <p>Energy-dependent endocytosis is responsible for drug transcorneal penetration following the instillation of ophthalmic formulations containing indomethacin nanoparticles</p>. International Journal of Nanomedicine. Volume 14. 1213–1227. 67 indexed citations
17.
Nagai, Noriaki, et al.. (2019). Solid Nanocrystals of Rebamipide Promote Recovery from Indomethacin-Induced Gastrointestinal Bleeding. International Journal of Molecular Sciences. 20(20). 4990–4990. 6 indexed citations
18.
Nagai, Noriaki, et al.. (2017). Therapeutic Effect of Cilostazol Ophthalmic Nanodispersions on Retinal Dysfunction in Streptozotocin-Induced Diabetic Rats. International Journal of Molecular Sciences. 18(9). 1971–1971. 20 indexed citations
19.
Nagai, Noriaki, et al.. (2017). Amyloid β 1–43 Accumulates in the Lens Epithelium of Cortical Opacification in Japanese Patients. Investigative Ophthalmology & Visual Science. 58(7). 3294–3294. 3 indexed citations
20.
Otake, Hiroko, et al.. (2000). A case of primary leiomyosarcoma of the thyroid.. The Journal of the Japanese Society of Clinical Cytology. 39(4). 258–262.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Sinar Sayed Breakdown of academic impact, for papers by Sadek Ahmed Breakdown of academic impact, for papers by Jayamanti Pandit Breakdown of academic impact, for papers by Joana Araújo Breakdown of academic impact, for papers by Dongzhi Hou Breakdown of academic impact, for papers by Yanzhong Chen Breakdown of academic impact, for papers by Hanan Refai Breakdown of academic impact, for papers by Miguel González‐Barcia Breakdown of academic impact, for papers by Nurşen Ünlü Breakdown of academic impact, for papers by Aditya Konar
Rankless by CCL
2026