Hiroki Sekine

4.1k total citations · 1 hit paper
50 papers, 3.1k citations indexed

About

Hiroki Sekine is a scholar working on Molecular Biology, Cancer Research and Immunology. According to data from OpenAlex, Hiroki Sekine has authored 50 papers receiving a total of 3.1k indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Molecular Biology, 9 papers in Cancer Research and 8 papers in Immunology. Recurrent topics in Hiroki Sekine's work include Genomics, phytochemicals, and oxidative stress (8 papers), Cancer, Hypoxia, and Metabolism (6 papers) and Erythropoietin and Anemia Treatment (5 papers). Hiroki Sekine is often cited by papers focused on Genomics, phytochemicals, and oxidative stress (8 papers), Cancer, Hypoxia, and Metabolism (6 papers) and Erythropoietin and Anemia Treatment (5 papers). Hiroki Sekine collaborates with scholars based in Japan, United States and Singapore. Hiroki Sekine's co-authors include Hozumi Motohashi, Masayuki Yamamoto, Ryo Funayama, Eri Kobayashi, Makiko Hayashi, Takafumi Suzuki, Nobuyuki Tanaka, Takeshi Nagashima, Keiko Nakayama and Takashi Moriguchi and has published in prestigious journals such as Nature, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Hiroki Sekine

48 papers receiving 3.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

2016 1.4k citations Hiroki Sekine, Hozumi Motohashi et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Hiroki Sekine Japan	24	1.8k	633	401	278	192	50	3.1k
Phuong Le United States	34	2.1k 1.2×	310 0.5×	314 0.8×	458 1.6×	295 1.5×	75	4.0k
Masayuki Niwa Japan	33	1.7k 1.0×	520 0.8×	220 0.5×	464 1.7×	206 1.1×	197	3.8k
David J. MacEwan United Kingdom	38	2.6k 1.5×	948 1.5×	684 1.7×	487 1.8×	196 1.0×	93	4.5k
Eri Kobayashi Japan	19	1.4k 0.8×	516 0.8×	153 0.4×	218 0.8×	156 0.8×	40	2.5k
Jamie D. Croxtall United Kingdom	33	1.7k 1.0×	911 1.4×	410 1.0×	433 1.6×	306 1.6×	74	3.9k
Yi Shen China	32	1.0k 0.6×	770 1.2×	236 0.6×	277 1.0×	370 1.9×	91	3.1k
Ling Zhang China	30	1.7k 1.0×	424 0.7×	318 0.8×	224 0.8×	173 0.9×	159	3.1k
Hitoshi Miyazaki Japan	35	2.2k 1.2×	499 0.8×	216 0.5×	794 2.9×	182 0.9×	162	4.4k
Liping Chen China	33	2.0k 1.1×	238 0.4×	725 1.8×	395 1.4×	195 1.0×	221	3.8k
Angela Avenoso Italy	38	903 0.5×	332 0.5×	326 0.8×	169 0.6×	107 0.6×	103	3.9k

Countries citing papers authored by Hiroki Sekine

Since Specialization

Citations

This map shows the geographic impact of Hiroki Sekine's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hiroki Sekine with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hiroki Sekine more than expected).

Fields of papers citing papers by Hiroki Sekine

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hiroki Sekine. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hiroki Sekine. The network helps show where Hiroki Sekine may publish in the future.

Co-authorship network of co-authors of Hiroki Sekine

This figure shows the co-authorship network connecting the top 25 collaborators of Hiroki Sekine. A scholar is included among the top collaborators of Hiroki Sekine based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hiroki Sekine. Hiroki Sekine is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Sekine, Hiroki, Takaaki Akaike, & Hozumi Motohashi. (2025). Oxygen needs sulfur, sulfur needs oxygen: a relationship of interdependence. The EMBO Journal. 44(12). 3307–3326. 4 indexed citations

Suzuki, Norio, Koichiro Kato, Koji Sato, et al.. (2024). Crosstalk between oxygen signaling and iron metabolism in renal interstitial fibroblasts. Journal of Clinical Biochemistry and Nutrition. 74(3). 179–184. 4 indexed citations

Alam, Md. Morshedul, Hiroki Sekine, Takaaki Abe, et al.. (2023). Contribution of NRF2 to sulfur metabolism and mitochondrial activity. Redox Biology. 60. 102624–102624. 41 indexed citations

Takeda, Haruna, Yoshihiro Nakajima, Itaru Watanabe, et al.. (2023). The anti-inflammatory and anti-oxidative effect of a classical hypnotic bromovalerylurea mediated by the activation of NRF2. The Journal of Biochemistry. 174(2). 131–142. 6 indexed citations

Takeda, Haruna, Shohei Murakami, Zun Liu, et al.. (2023). Sulfur metabolic response in macrophage limits excessive inflammatory response by creating a negative feedback loop. Redox Biology. 65. 102834–102834. 25 indexed citations

Hayasaka, Kazuki, Shinya Ohkouchi, Ryoko Saito, et al.. (2023). Aging exacerbates murine lung ischemia-reperfusion injury by excessive inflammation and impaired tissue repair response. American Journal of Transplantation. 24(2). 293–303. 1 indexed citations

Sekine, Hiroki & Hozumi Motohashi. (2023). Unique and overlapping roles of NRF2 and NRF1 in transcriptional regulation. Journal of Clinical Biochemistry and Nutrition. 74(2). 91–96. 6 indexed citations

Nakamura, Hideaki, Hiroki Sekine, Hiroyuki Kato, et al.. (2022). Hypoxia-inducible factor-1α and poly [ADP ribose] polymerase 1 cooperatively regulate Notch3 expression under hypoxia via a noncanonical mechanism. Journal of Biological Chemistry. 298(7). 102137–102137. 4 indexed citations

Sato, Koji, Ikuo Hirano, Hiroki Sekine, et al.. (2019). An immortalized cell line derived from renal erythropoietin-producing (REP) cells demonstrates their potential to transform into myofibroblasts. Scientific Reports. 9(1). 11254–11254. 29 indexed citations

10.

Sekine, Hiroki, Tatsuya Miyamoto, T. Terashige, et al.. (2019). Evaluating intrinsic mobility from transient terahertz conductivity spectra of microcrystal samples of organic molecular semiconductors. Applied Physics Letters. 115(14). 5 indexed citations

11.

Souma, Tomokazu, Masahiro Nezu, Daisuke Nakano, et al.. (2015). Erythropoietin Synthesis in Renal Myofibroblasts Is Restored by Activation of Hypoxia Signaling. Journal of the American Society of Nephrology. 27(2). 428–438. 129 indexed citations

12.

Sekine, Hiroki, et al.. (2012). Effects of zinc deficiency and supplementation on gene expression of bitter taste receptors (TAS2Rs) on the tongue in rats. The Laryngoscope. 122(11). 2411–2417. 15 indexed citations

13.

Yokoyama, Atsushi, Yosuke Okuno, Toshihiro Chikanishi, et al.. (2010). KIAA1718 is a histone demethylase that erases repressive histone methyl marks. Genes to Cells. 15(8). 867–873. 29 indexed citations

14.

Yamanouchi, Naoto, Shinichi Okada, Kazuhiro Kodama, et al.. (2009). Effects of MRI abnormalities on WAIS-R performance in solvent abusers. Acta Neurologica Scandinavica. 96(1). 34–39. 10 indexed citations

15.

Oshima, Motohiko, et al.. (2009). SUMO Modification Regulates the Transcriptional Repressor Function of Aryl Hydrocarbon Receptor Repressor. Journal of Biological Chemistry. 284(17). 11017–11026. 23 indexed citations

16.

Sekine, Hiroki, Junsei Mimura, Masayuki Yamamoto, & Yoshiaki Fujii‐Kuriyama. (2006). Unique and Overlapping Transcriptional Roles of Arylhydrocarbon Receptor Nuclear Translocator (Arnt) and Arnt2 in Xenobiotic and Hypoxic Responses. Journal of Biological Chemistry. 281(49). 37507–37516. 47 indexed citations

17.

Sekine, Hiroki, Yasuo Kikuchi, Chikahisa Takasaki, et al.. (2002). HIF-1α-prolyl hydroxylase: molecular target of nitric oxide in the hypoxic signal transduction pathway. Biochemical and Biophysical Research Communications. 295(3). 657–662. 55 indexed citations

18.

Noda, S., Naoto Yamanouchi, Seiji Okada, et al.. (1996). Proton MR Spectroscopy in Solvent Abusers^a. Annals of the New York Academy of Sciences. 801(1). 441–451. 7 indexed citations

19.

Takeuchi, Tsutomu, et al.. (1995). Systemic lupus erythematosus with necrotizing vasculitis and upregulated expression of VLA-4 antigen. Clinical Rheumatology. 14(3). 370–374. 8 indexed citations

20.

Amano, Kouichi, Hiroki Sekine, Osamu Hosono, et al.. (1994). An unusual variant of Wegener's granulomatosis and the role of integrin adhesion receptors for pulmonary lesion. 5(3). 217–226. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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