David J. MacEwan

8.9k citations

93 papers · 4.5k indexed · h-index 38

Impact in

Cancer Research top 2%
- NF-κB Signaling Pathways
Immunology top 2%
- Immune Response and Inflammation

Papers in

Cancer Research 19
- NF-κB Signaling Pathways 13
Immunology 21
- Immune Response and Inflammation 10

Co-authors: Stuart A. Rushworth Kristian M. Bowles Lyubov Zaitseva Megan Y. Murray Graeme Milligan Peter Vandenabeele Michelle Connell Shona M. McFarlane
Journals: Biochemical Society Transactions (8 papers)FEBS Letters (8 papers)Biochemical Journal (5 papers)Cell Cycle (5 papers)The Journal of Immunology (4 papers)
Partner nations: United Kingdom Belgium United States

In The Last Decade

David J. MacEwan

92 papers receiving 4.4k citations

Peers

Countries citing papers authored by David J. MacEwan

Since Specialization

Citations

This map shows the geographic impact of David J. MacEwan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David J. MacEwan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David J. MacEwan more than expected).

Fields of papers citing papers by David J. MacEwan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David J. MacEwan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David J. MacEwan. The network helps show where David J. MacEwan may publish in the future.

Co-authors

The 25 scholars most cited alongside David J. MacEwan, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David J. MacEwan Line = papers co-authored together David J. MacEwan links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Activation of Human CD8+ T Cells with Nitroso Dapsone–Modified HLA-B13:01–Binding Peptides The Journal of Immunology* ·Mubarak Almutairi, Adam Lister, Qing Zhao, شريف إسماعيل الحلبي, Patricia De Assis Lelo Coutinho, Arun Tailor, J. Waddington, Variance Mokam Fotso, Joshua Gardner, Paul Thomson, C. Stirling‐Reed, Yonghu Sun, Lele Sun, David A. Ostrov, Hong Liu, David J. MacEwan, Munir Pirmohamed, Xiaoli Meng, Furen Zhang, Dean J. Naisbitt	2023	3
2	Kinobead Profiling Reveals Reprogramming of BCR Signaling in Response to Therapy within Primary CLL Cells Clinical Cancer Research ·Adam J. Linley, Alessandra Saggio, J. R. Smeets, Annalisa D’Avola, Feng Zi-Chao, Silvia Cicconi, Rebecca Griffin, Francesco Forconi, Andrew R. Pettitt, Nagesh Kalakonda, Andy C. Rawstron, Peter Hillmen, Andrew J. Steele, David J. MacEwan, Graham Packham, Ian A. Prior, Joseph R. Slupsky	2021	4
3	Characterization of a high throughput human stem cell cardiomyocyte assay to predict drug-induced changes in clinical electrocardiogram parameters European Journal of Pharmacology ·Peter J. Kilfoil, Naoki Sakurai, Adam Takeshita, Literatur Über, Derek J. Leishman, Dingzhou Li, David J. MacEwan, Parveen Sharma, Eric D. Watt, Stephen Jenkinson	2021	9
4	HLA Class-II‒Restricted CD8+ T Cells Contribute to the Promiscuous Immune Response in Dapsone-Hypersensitive Patients Journal of Investigative Dermatology ·Qing Zhao, Mubarak Almutairi, Arun Tailor, Enni Suonperä, C. Stirling‐Reed, شريف إسماعيل الحلبي, Xiaoli Meng, Manuel B. Aalbers, Kanoot Jaruthamsophon, Chonlaphat Sukasem, Yonghu Sun, Lele Sun, Monday O. Ogese, David J. MacEwan, Munir Pirmohamed, Jianjun Liu, David A. Ostrov, Hong Liu, Furen Zhang, Dean J. Naisbitt	2021	16
5	The importance of Ras in drug resistance in cancer British Journal of Pharmacology ·Fiona Healy, Ian A. Prior, David J. MacEwan	2021	39
6	New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome Cancer Research ·X. Wang, Adam J. Linley, Dean E. Hammond, Fiona E. Hood, Judy M. Coulson, David J. MacEwan, Sarah J. Ross, Joseph R. Slupsky, Paul D. Smith, Patrick A. Eyers, Ian A. Prior	2017	117
7	NRF2-driven miR-125B1 and miR-29B1 transcriptional regulation controls a novel anti-apoptotic miRNA regulatory network for AML survival Cell Death and Differentiation ·Niraj Shah, Lyubov Zaitseva, Kristian M. Bowles, David J. MacEwan, Stuart A. Rushworth	2014	55
8	Attenuation of dexamethasone-induced cell death in multiple myeloma is mediated by miR-125b expression Cell Cycle ·Megan Y. Murray, Stuart A. Rushworth, Lyubov Zaitseva, Kristian M. Bowles, David J. MacEwan	2013	60
9	Bortezomib induces heme oxygenase-1 expression in multiple myeloma Cell Cycle ·Lawrence N. Barrera, Stuart A. Rushworth, Kristian M. Bowles, David J. MacEwan	2012	41
10	High Basal Nuclear Levels of Nrf2 in Acute Myeloid Leukemia Reduces Sensitivity to Proteasome Inhibitors Cancer Research ·Stuart A. Rushworth, Kristian M. Bowles, David J. MacEwan	2011	71
11	Silencing FLIP_L modifies TNF-induced apoptotic protein expression Cell Cycle ·Lyubov Zaitseva, Stuart A. Rushworth, David J. MacEwan	2011	6
12	NF-κB–Inhibited Acute Myeloid Leukemia Cells Are Rescued from Apoptosis by Heme Oxygenase-1 Induction Cancer Research ·Stuart A. Rushworth, Kristian M. Bowles, Prahlad V. Raninga, David J. MacEwan	2010	53
13	Lipopolysaccharide-Induced Expression of NAD(P)H:Quinone Oxidoreductase 1 and Heme Oxygenase-1 Protects against Excessive Inflammatory Responses in Human Monocytes The Journal of Immunology ·Stuart A. Rushworth, David J. MacEwan, Maria A. O’Connell	2008	183
14	TNF signaling gets FLIPped off: TNF-induced regulation of FLIP Cell Cycle ·Stuart A. Rushworth, Alison Taylor, Susana Langa, David J. MacEwan	2008	8
15	The influence of alkyl pyridinium sponge toxins on membrane properties, cytotoxicity, transfection and protein expression in mammalian cells Biochimica et Biophysica Acta (BBA) - Biomembranes ·Steven Tucker, D. E. McClelland, Marcel Jaspars, Kristina Sepčić, David J. MacEwan, Roderick H. Scott	2003	32
16	Actions of cannabinoid receptor ligands on rat cultured sensory neurones: implications for antinociception Neuropharmacology ·Ruth A. Ross, Angela A. Coutts, Shona M. McFarlane, Sharon Anavi‐Goffer, Andrew J. Irving, Roger G. Pertwee, David J. MacEwan, Roderick H. Scott	2001	147
17	Selective down-regulation of the Cqα/G11α G-protein family in tumour necrosis factor-α induced cell death Molecular and Cellular Biochemistry ·Valerie P. Pollock, Nicole Kessler Snook, Orla J. Jupp, Stephen B. Gauld, H Anderson, David J. MacEwan	2000	18
18	Protein kinase C isoforms in pituitary cells displaying differential sensitivity to phorbol ester Molecular and Cellular Biochemistry ·David J. MacEwan, Melanie S. Johnson, Rory Mitchell	1999	12
19	Tumor Necrosis Factor-α Mediates Both Apoptotic Cell Death and Cell Proliferation in a Human Hematopoietic Cell Line Dependent on Mitotic Activity and Receptor Subtype Expression Journal of Biological Chemistry ·Gregory T. Baxter, Richard C. Kuo, Orla J. Jupp, Peter Vandenabeele, David J. MacEwan	1999	83
20	Involvement of multiple protein kinase C isozymes in the ACTH secretory pathway of AtT‐20 cells British Journal of Pharmacology ·Brian W. McFerran, David J. MacEwan, Simon Guild	1995	14

About David J. MacEwan

David J. MacEwan is a scholar working on Cancer Research, Immunology, Molecular Biology, Genetics and Cellular and Molecular Neuroscience, having authored 93 papers that have together received 4.5k indexed citations. Recurring topics across this work include Protein Kinase Regulation and GTPase Signaling (19 papers), Cell death mechanisms and regulation (13 papers), Receptor Mechanisms and Signaling (13 papers), NF-κB Signaling Pathways (13 papers), Genomics, phytochemicals, and oxidative stress (10 papers), Immune Response and Inflammation (10 papers), Chronic Lymphocytic Leukemia Research (9 papers) and Neuroscience and Neuropharmacology Research (8 papers). The work is most often cited by research in Cancer Research (684 citations), Immunology (948 citations), Hematology (415 citations), Molecular Biology (2.6k citations) and Cellular and Molecular Neuroscience (644 citations). David J. MacEwan has collaborated with scholars based in United Kingdom, Belgium and United States. Frequent co-authors include Stuart A. Rushworth, Kristian M. Bowles, Lyubov Zaitseva, Megan Y. Murray, Graeme Milligan, Peter Vandenabeele, Michelle Connell, Shona M. McFarlane, Niraj Shah and Maria A. O’Connell. Their work appears in journals such as Biochemical Society Transactions, FEBS Letters, Biochemical Journal, Cell Cycle and The Journal of Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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