Hideaki Higashi

8.6k total citations · 2 hit papers
102 papers, 7.0k citations indexed

About

Hideaki Higashi is a scholar working on Molecular Biology, Immunology and Surgery. According to data from OpenAlex, Hideaki Higashi has authored 102 papers receiving a total of 7.0k indexed citations (citations by other indexed papers that have themselves been cited), including 55 papers in Molecular Biology, 32 papers in Immunology and 31 papers in Surgery. Recurrent topics in Hideaki Higashi's work include Helicobacter pylori-related gastroenterology studies (28 papers), Galectins and Cancer Biology (25 papers) and Bacillus and Francisella bacterial research (18 papers). Hideaki Higashi is often cited by papers focused on Helicobacter pylori-related gastroenterology studies (28 papers), Galectins and Cancer Biology (25 papers) and Bacillus and Francisella bacterial research (18 papers). Hideaki Higashi collaborates with scholars based in Japan, United States and Zambia. Hideaki Higashi's co-authors include Masanori Hatakeyama, Takeshi Azuma, Ryouhei Tsutsumi, Masahiro Asaka, Shiho Yamazaki, Toshiro Sugiyama, Yoichi Taya, Masatoshi Kitagawa, Naomi Ohnishi and Ikuko Suzuki‐Takahashi and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Hideaki Higashi

97 papers receiving 6.9k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

SHP-2 Tyrosine Phosphatase as an Intracellular Target of Helicobacter pylori CagA Protein

2002 856 citations Hideaki Higashi, Ryouhei Tsutsumi et al. Science profile →
The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2.

1996 518 citations Masatoshi Kitagawa, Hideaki Higashi et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Hideaki Higashi Japan	34	4.3k	3.3k	2.4k	1.2k	834	102	7.0k
Markus Gerhard Germany	42	3.5k 0.8×	2.3k 0.7×	2.1k 0.9×	928 0.8×	822 1.0×	129	6.3k
Judith Romero–Gallo United States	37	2.8k 0.7×	1.5k 0.4×	1.5k 0.6×	651 0.5×	809 1.0×	81	4.2k
Hiroyoshi Ota Japan	39	3.7k 0.9×	1.3k 0.4×	1.3k 0.5×	722 0.6×	1.6k 1.9×	240	6.0k
Dawn A. Israel United States	32	3.0k 0.7×	1.7k 0.5×	1.2k 0.5×	286 0.2×	566 0.7×	52	4.2k
Nicole Porchet France	48	1.5k 0.3×	1.4k 0.4×	4.6k 1.9×	1.5k 1.3×	970 1.2×	138	7.0k
James R. Gum United States	48	1.3k 0.3×	1.3k 0.4×	4.8k 2.0×	1.7k 1.4×	788 0.9×	85	7.4k
Charles A. Dangler United States	30	2.2k 0.5×	906 0.3×	1.0k 0.4×	400 0.3×	667 0.8×	61	4.3k
Debra D. Donaldson United States	40	871 0.2×	6.2k 1.9×	1.4k 0.6×	1.5k 1.3×	1.7k 2.0×	58	10.9k
P Ghiara Italy	26	3.5k 0.8×	2.9k 0.9×	775 0.3×	231 0.2×	449 0.5×	66	4.9k
Philip J. Bergman United States	34	598 0.1×	1.0k 0.3×	1.7k 0.7×	720 0.6×	2.2k 2.7×	113	5.2k

Countries citing papers authored by Hideaki Higashi

Since Specialization

Citations

This map shows the geographic impact of Hideaki Higashi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hideaki Higashi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hideaki Higashi more than expected).

Fields of papers citing papers by Hideaki Higashi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hideaki Higashi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hideaki Higashi. The network helps show where Hideaki Higashi may publish in the future.

Co-authorship network of co-authors of Hideaki Higashi

This figure shows the co-authorship network connecting the top 25 collaborators of Hideaki Higashi. A scholar is included among the top collaborators of Hideaki Higashi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hideaki Higashi. Hideaki Higashi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Thapa, Jeewan, Apichai Tuanyok, Vannarat Saechan, et al.. (2025). A novel ready-to-use loop-mediated isothermal amplification (LAMP) method for detection of Burkholderia mallei and B. pseudomallei. BMC Microbiology. 25(1). 36–36. 1 indexed citations

Ndebe, Joseph, Chie Nakajima, Masahiro Kajihara, et al.. (2024). Detection of Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacteriaceae from Diseased Broiler Chickens in Lusaka District, Zambia. Antibiotics. 13(3). 259–259. 3 indexed citations

Li, Ruiyu, Manabu Nagao, Jeewan Thapa, et al.. (2024). Chlamydia trachomatis L2 434/Bu readily activates glycolysis under hypoxia for efficient metabolism. Biochemical and Biophysical Research Communications. 736. 150461–150461.

Kobayashi, Ayako, et al.. (2023). Baseline and seasonal trends of Bacillus cereus and Bacillus subtilis from clinical samples in Japan. Infection Prevention in Practice. 5(2). 100272–100272. 6 indexed citations

Paudel, Atmika, Yoshikazu Furuta, & Hideaki Higashi. (2021). Silkworm model for Bacillus anthracis infection and virulence determination. Virulence. 12(1). 2285–2295. 7 indexed citations

Itō, Satoshi, et al.. (2021). Risk factors and spatio-temporal patterns of livestock anthrax in Khuvsgul Province, Mongolia. PLoS ONE. 16(11). e0260299–e0260299. 6 indexed citations

Okuya, Kosuke, Reiko Yoshida, Rashid Manzoor, et al.. (2020). Potential Role of Nonneutralizing IgA Antibodies in Cross-Protective Immunity against Influenza A Viruses of Multiple Hemagglutinin Subtypes. Journal of Virology. 94(12). 27 indexed citations

Furuta, Yoshikazu, et al.. (2019). Geographic distribution of cattle anthrax in Western Zambia. Jūigaku kenkyū/Japanese journal of veterinary research. 67(2). 195–202. 2 indexed citations

Ohnishi, Takashi, Katsuhisa Yamada, Koji Iwasaki, et al.. (2019). Caspase-3 knockout inhibits intervertebral disc degeneration related to injury but accelerates degeneration related to aging. Scientific Reports. 9(1). 19324–19324. 27 indexed citations

10.

Furuta, Yoshikazu, Emiko Ito, Fumito Maruyama, et al.. (2018). Loss of Bacitracin Resistance Due to a Large Genomic Deletion among Bacillus anthracis Strains. mSystems. 3(5). 6 indexed citations

11.

Murata‐Kamiya, Naoko, Kenji Kikuchi, Takeru Hayashi, Hideaki Higashi, & Masanori Hatakeyama. (2010). Helicobacter pylori Exploits Host Membrane Phosphatidylserine for Delivery, Localization, and Pathophysiological Action of the CagA Oncoprotein. Cell Host & Microbe. 7(5). 399–411. 125 indexed citations

12.

Ohnishi, Naomi, Shinya Tanaka, Hirofumi Sawa, et al.. (2008). Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse. Proceedings of the National Academy of Sciences. 105(3). 1003–1008. 468 indexed citations

13.

Saito, Yasuhiro, et al.. (2008). Structural and functional diversity in the PAR1b/MARK2‐binding region of Helicobacter pylori CagA. Cancer Science. 99(10). 2004–2011. 56 indexed citations

14.

Tsutsumi, Ryouhei, Atsushi Takahashi, Takeshi Azuma, Hideaki Higashi, & Masanori Hatakeyama. (2005). Focal Adhesion Kinase Is a Substrate and Downstream Effector of SHP-2 Complexed with Helicobacter pylori CagA. Molecular and Cellular Biology. 26(1). 261–276. 164 indexed citations

15.

Higuchi, Megumi, Ryouhei Tsutsumi, Hideaki Higashi, & Masanori Hatakeyama. (2004). Conditional gene silencing utilizing the lac repressor reveals a role of SHP‐2 in cagA‐positive Helicobacter pylori pathogenicity. Cancer Science. 95(5). 442–447. 45 indexed citations

16.

Higashi, Hideaki, Akihiro Nakaya, Ryouhei Tsutsumi, et al.. (2004). Helicobacter pylori CagA Induces Ras-independent Morphogenetic Response through SHP-2 Recruitment and Activation. Journal of Biological Chemistry. 279(17). 17205–17216. 221 indexed citations

17.

Higashi, Hideaki, Ryouhei Tsutsumi, Toshiro Sugiyama, et al.. (2002). SHP-2 Tyrosine Phosphatase as an Intracellular Target of Helicobacter pylori CagA Protein. Science. 295(5555). 683–686. 856 indexed citations breakdown →

18.

Mizuguchi, Rumiko, et al.. (2000). Ras and Signal Transducer and Activator of Transcription (STAT) Are Essential and Sufficient Downstream Components of Janus Kinases in Cell Proliferation. Japanese Journal of Cancer Research. 91(5). 527–533. 12 indexed citations

19.

Higashi, Hideaki, Ikuko Suzuki‐Takahashi, Yoichi Taya, et al.. (1995). Differences in Substrate Specificity between Cdk2-Cyclin A and Cdk2-Cyclin E in Vitro. Biochemical and Biophysical Research Communications. 216(2). 520–525. 26 indexed citations

20.

Kitagawa, Masanobu, Hideaki Higashi, Taijiro Okabe, et al.. (1994). A cyclin-dependent kinase inhibitor, butyrolactone I, inhibits phosphorylation of RB protein and cell cycle progression.. PubMed. 9(9). 2549–57. 103 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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