Helga Refsum

38.5k total citations · 13 hit papers
301 papers, 28.1k citations indexed

About

Helga Refsum is a scholar working on Rheumatology, Surgery and Clinical Biochemistry. According to data from OpenAlex, Helga Refsum has authored 301 papers receiving a total of 28.1k indexed citations (citations by other indexed papers that have themselves been cited), including 248 papers in Rheumatology, 91 papers in Surgery and 53 papers in Clinical Biochemistry. Recurrent topics in Helga Refsum's work include Folate and B Vitamins Research (247 papers), Esophageal and GI Pathology (79 papers) and Metabolism and Genetic Disorders (52 papers). Helga Refsum is often cited by papers focused on Folate and B Vitamins Research (247 papers), Esophageal and GI Pathology (79 papers) and Metabolism and Genetic Disorders (52 papers). Helga Refsum collaborates with scholars based in Norway, United Kingdom and United States. Helga Refsum's co-authors include Per Magne Ueland, A. David Smith, Dan J. Stein, Ottar Nygård, Grethe S. Tell, Jørn Schneede, Robert Clarke, Jan Erik Nordrehaug, Carole Johnston and Aage Tverdal and has published in prestigious journals such as Proceedings of the National Academy of Sciences, The Lancet and JAMA.

In The Last Decade

Helga Refsum

296 papers receiving 27.0k citations

Hit Papers

Homocysteine and Cardiova... 1989 2026 2001 2013 1998 1998 1995 2004 1995 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Homocysteine and Cardiovascular Disease
    1998 1.8k citations Helga Refsum, Per Magne Ueland et al. profile →
  2. Folate, Vitamin B12, and Serum Total Homocysteine Levels in Confirmed Alzheimer Disease
    1998 1.1k citations A. David Smith, Helga Refsum et al. profile →
  3. Total Plasma Homocysteine and Cardiovascular Risk Profile
    1995 903 citations Helga Refsum, Per Magne Ueland et al. profile →
  4. Facts and Recommendations about Total Homocysteine Determinations: An Expert Opinion
    2004 827 citations Helga Refsum, A. David Smith et al. profile →
  5. Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men
    1995 707 citations Helga Refsum, Per Magne Ueland et al. profile →
  6. Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study
    2007 568 citations Helga Refsum et al. profile →
  7. Homocysteine-Lowering by B Vitamins Slows the Rate of Accelerated Brain Atrophy in Mild Cognitive Impairment: A Randomized Controlled Trial
    2010 545 citations A. David Smith, Helga Refsum et al. profile →
  8. Serum Total Homocysteine and Coronary Heart Disease
    1995 533 citations Helga Refsum, Per Magne Ueland et al. profile →
  9. Plasma homocysteine, a risk factor for vascular disease: plasma levels in health, disease, and drug therapy.
    1989 522 citations Per Magne Ueland, Helga Refsum profile →
  10. Is folic acid good for everyone?
    2008 434 citations A. David Smith, Helga Refsum et al. profile →
  11. Homocysteine, B Vitamins, and Cognitive Impairment
    2016 368 citations A. David Smith, Helga Refsum profile →
  12. Preventing Alzheimer’s disease-related gray matter atrophy by B-vitamin treatment
    2013 362 citations Helga Refsum, A. David Smith et al. profile →
  13. Homocysteine – from disease biomarker to disease prevention
    2021 148 citations A. David Smith, Helga Refsum profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Helga Refsum 19.3k 6.7k 4.7k 3.7k 3.7k 301 28.1k
Jacob Selhub 25.6k 1.3× 9.2k 1.4× 4.8k 1.0× 3.8k 1.0× 7.0k 1.9× 382 37.7k
Per Magne Ueland 24.0k 1.2× 8.1k 1.2× 5.8k 1.2× 5.0k 1.4× 8.1k 2.2× 663 40.9k
Henk J. Blom 15.3k 0.8× 5.8k 0.9× 1.9k 0.4× 4.1k 1.1× 4.7k 1.3× 383 23.6k
Irwin H. Rosenberg 11.9k 0.6× 5.6k 0.8× 6.4k 1.4× 2.1k 0.6× 3.3k 0.9× 285 25.6k
Sally P. Stabler 8.9k 0.5× 2.4k 0.4× 1.6k 0.3× 1.5k 0.4× 3.0k 0.8× 182 14.6k
Anne M. Molloy 7.4k 0.4× 2.2k 0.3× 1.1k 0.2× 2.7k 0.7× 2.0k 0.5× 263 11.8k
Steven H. Zeisel 7.0k 0.4× 1.2k 0.2× 4.1k 0.9× 4.7k 1.3× 7.4k 2.0× 348 23.7k
Robert Clarke 5.5k 0.3× 4.3k 0.6× 2.5k 0.5× 849 0.2× 1.9k 0.5× 211 17.0k
Ottar Nygård 5.8k 0.3× 2.5k 0.4× 2.1k 0.4× 942 0.3× 2.1k 0.6× 238 11.4k
Michael Y. Tsai 2.1k 0.1× 3.8k 0.6× 3.4k 0.7× 1.1k 0.3× 3.2k 0.9× 412 16.1k

Countries citing papers authored by Helga Refsum

Since Specialization
Citations

This map shows the geographic impact of Helga Refsum's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Helga Refsum with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Helga Refsum more than expected).

Fields of papers citing papers by Helga Refsum

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Helga Refsum. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Helga Refsum. The network helps show where Helga Refsum may publish in the future.

Co-authorship network of co-authors of Helga Refsum

This figure shows the co-authorship network connecting the top 25 collaborators of Helga Refsum. A scholar is included among the top collaborators of Helga Refsum based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Helga Refsum. Helga Refsum is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Yates, Abi G., Dawn Shepherd, Elisabete Pires, et al.. (2025). Role of B vitamins in modulating homocysteine and metabolic pathways linked to brain atrophy: Metabolomics insights from the VITACOG trial. Alzheimer s & Dementia. 21(7). e70521–e70521.
2.
Olsén, Thomas, Kathrine J. Vinknes, M. Eline Kooi, et al.. (2024). Estimated stearoyl-CoA desaturase activity mediates the associations of total cysteine with adiposity: The Maastricht Study. Journal of clinical lipidology. 19(2). 348–357. 1 indexed citations
3.
Grande, Giulia, Babak Hooshmand, Davide Liborio Vetrano, et al.. (2023). Association of Long-term Exposure to Air Pollution and Dementia Risk. Neurology. 101(12). e1231–e1240. 10 indexed citations
4.
5.
Nichenametla, Sailendra N., Dwight A.L. Mattocks, Vishal Midya, et al.. (2022). Cysteine restriction‐specific effects of sulfur amino acid restriction on lipid metabolism. Aging Cell. 21(12). e13739–e13739. 18 indexed citations
6.
Elshorbagy, Amany, Frans C. H. Bakers, Martijn C.G.J. Brouwers, et al.. (2022). Associations between plasma sulfur amino acids and specific fat depots in two independent cohorts: CODAM and The Maastricht Study. European Journal of Nutrition. 62(2). 891–904. 9 indexed citations
7.
Elshorbagy, Amany, Cheryl Turner, Nasser E. Bastani, Helga Refsum, & Timothy Kwok. (2022). The association of serum sulfur amino acids and related metabolites with incident diabetes: a prospective cohort study. European Journal of Nutrition. 61(6). 3161–3173. 12 indexed citations
8.
Wu, Yuanyuan, A. David Smith, Nasser E. Bastani, Helga Refsum, & Timothy Kwok. (2021). The dihydrofolate reductase 19-bp deletion modifies the beneficial effect of B-vitamin therapy in mild cognitive impairment: pooled study of two randomized placebo-controlled trials. Human Molecular Genetics. 31(7). 1151–1158. 9 indexed citations
9.
Mehanna, Radwa A., et al.. (2021). Extracellular cystine influences human preadipocyte differentiation and correlates with fat mass in healthy adults. Amino Acids. 53(10). 1623–1634. 16 indexed citations
10.
Vinknes, Kathrine J., Helga Refsum, Cheryl Turner, et al.. (2020). Plasma Sulfur Amino Acids and Risk of Cerebrovascular Diseases. Stroke. 52(1). 172–180. 8 indexed citations
11.
Vinknes, Kathrine J., Eha Nurk, Grethe S. Tell, et al.. (2017). The relation of CUN-BAE index and BMI with body fat, cardiovascular events and diabetes during a 6-year follow-up: the Hordaland Health Study. Clinical Epidemiology. Volume 9. 555–566. 27 indexed citations
12.
Kumar, Tivendra, Sunita Taneja, Harshpal Singh Sachdev, et al.. (2016). Supplementation of vitamin B12 or folic acid on hemoglobin concentration in children 6–36 months of age: A randomized placebo controlled trial. Clinical Nutrition. 36(4). 986–991. 11 indexed citations
13.
Vogiatzoglou, Anna, A. David Smith, Eha Nurk, et al.. (2012). Cognitive Function in an Elderly Population. Psychosomatic Medicine. 75(1). 20–29. 56 indexed citations
14.
Antoniades, Charalambos, Cheerag Shirodaria, N Warrick, et al.. (2006). 5-Methyltetrahydrofolate Rapidly Improves Endothelial Function and Decreases Superoxide Production in Human Vessels. Circulation. 114(11). 1193–1201. 289 indexed citations
15.
Refsum, Helga. (2001). Folate, vitamin B12 and homocysteine in relation to birth defects and pregnancy outcome. British Journal Of Nutrition. 85(S2). S109–S109. 126 indexed citations
16.
Refsum, Helga. (2001). Folate, vitamin B12 and homocysteine in relation to birth defects and pregnancy outcome. British Journal Of Nutrition. 85(S2). S109–S109. 112 indexed citations
17.
Robinson, Killian, Kristopher L. Arheart, Helga Refsum, et al.. (1998). Low Circulating Folate and Vitamin B 6 Concentrations. Circulation. 97(5). 437–443. 422 indexed citations
18.
Refsum, Helga & Per Magne Ueland. (1998). Recent data are not in conflict with homocysteine as a cardiovascular risk factor. Current Opinion in Lipidology. 9(6). 533–539. 62 indexed citations
19.
Fiskerstrand, Torunn, Per Magne Ueland, & Helga Refsum. (1997). Response of the methionine synthase system to short‐term culture with homocysteine and nitrous oxide and its relation to methionine dependence. International Journal of Cancer. 72(2). 301–306. 1 indexed citations
20.
Fiskerstrand, Torunn, Per Magne Ueland, & Helga Refsum. (1997). Response of the methionine synthase system to short-term culture with homocysteine and nitrous oxide and its relation to methionine dependence. International Journal of Cancer. 72(2). 301–306. 6 indexed citations

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