Jacob Selhub

49.2k total citations · 9 hit papers
382 papers, 37.7k citations indexed

About

Jacob Selhub is a scholar working on Rheumatology, Surgery and Molecular Biology. According to data from OpenAlex, Jacob Selhub has authored 382 papers receiving a total of 37.7k indexed citations (citations by other indexed papers that have themselves been cited), including 326 papers in Rheumatology, 115 papers in Surgery and 58 papers in Molecular Biology. Recurrent topics in Jacob Selhub's work include Folate and B Vitamins Research (322 papers), Esophageal and GI Pathology (103 papers) and Metabolism and Genetic Disorders (57 papers). Jacob Selhub is often cited by papers focused on Folate and B Vitamins Research (322 papers), Esophageal and GI Pathology (103 papers) and Metabolism and Genetic Disorders (57 papers). Jacob Selhub collaborates with scholars based in United States, Israel and Canada. Jacob Selhub's co-authors include Paul F. Jacques, Irwin H. Rosenberg, Andrew G. Bostom, Peter W.F. Wilson, Ralph B. D’Agostino, Philip A. Wolf, Martha Savaria Morris, Pamela J. Bagley, Marie Nadeau and Alexa Beiser and has published in prestigious journals such as New England Journal of Medicine, Proceedings of the National Academy of Sciences and The Lancet.

In The Last Decade

Jacob Selhub

377 papers receiving 36.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease

2002 2.7k citations Jacob Selhub, Paul F. Jacques et al. profile →
Relation Between Folate Status, a Common Mutation in Methylenetetrahydrofolate Reductase, and Plasma Homocysteine Concentrations

1996 1.2k citations Paul F. Jacques, Irwin H. Rosenberg et al. profile →
Multiple Biomarkers for the Prediction of First Major Cardiovascular Events and Death

2006 976 citations Paul F. Jacques, Jacob Selhub et al. profile →
HOMOCYSTEINE METABOLISM

1999 956 citations Jacob Selhub profile →
Association between Plasma Homocysteine Concentrations and Extracranial Carotid-Artery Stenosis

1995 943 citations Jacob Selhub, Paul F. Jacques et al. profile →
A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status

2002 749 citations Sang‐Woon Choi, Joel B. Mason et al. profile →
Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.

1997 651 citations Walter C. Willett, Jacob Selhub et al. profile →
Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort

2001 523 citations Paul F. Jacques, Peter W.F. Wilson et al. American Journal of Clinical Nutrition profile →
Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification

2007 462 citations Paul F. Jacques, Irwin H. Rosenberg et al. American Journal of Clinical Nutrition profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jacob Selhub United States	104	25.6k	9.2k	7.0k	4.8k	4.3k	382	37.7k
Per Magne Ueland Norway	97	24.0k 0.9×	8.1k 0.9×	8.1k 1.2×	5.8k 1.2×	4.5k 1.0×	663	40.9k
Helga Refsum Norway	83	19.3k 0.8×	6.7k 0.7×	3.7k 0.5×	4.7k 1.0×	3.4k 0.8×	301	28.1k
Henk J. Blom Netherlands	81	15.3k 0.6×	5.8k 0.6×	4.7k 0.7×	1.9k 0.4×	2.2k 0.5×	383	23.6k
Irwin H. Rosenberg United States	78	11.9k 0.5×	5.6k 0.6×	3.3k 0.5×	6.4k 1.3×	3.2k 0.7×	285	25.6k
Paul F. Jacques United States	100	11.9k 0.5×	5.8k 0.6×	6.1k 0.9×	9.1k 1.9×	9.4k 2.2×	431	39.1k
John M. Scott Ireland	61	10.0k 0.4×	3.0k 0.3×	2.6k 0.4×	1.3k 0.3×	1.6k 0.4×	263	13.6k
Sally P. Stabler United States	59	8.9k 0.3×	2.4k 0.3×	3.0k 0.4×	1.6k 0.3×	970 0.2×	182	14.6k
Gary C. Curhan United States	107	5.2k 0.2×	6.5k 0.7×	3.7k 0.5×	3.5k 0.7×	3.7k 0.9×	404	41.8k
Anne M. Molloy Ireland	55	7.4k 0.3×	2.2k 0.2×	2.0k 0.3×	1.1k 0.2×	1.5k 0.3×	263	11.8k
Robert Clarke United Kingdom	57	5.5k 0.2×	4.3k 0.5×	1.9k 0.3×	2.5k 0.5×	2.1k 0.5×	211	17.0k

Countries citing papers authored by Jacob Selhub

Since Specialization

Citations

This map shows the geographic impact of Jacob Selhub's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jacob Selhub with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jacob Selhub more than expected).

Fields of papers citing papers by Jacob Selhub

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jacob Selhub. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jacob Selhub. The network helps show where Jacob Selhub may publish in the future.

Co-authorship network of co-authors of Jacob Selhub

This figure shows the co-authorship network connecting the top 25 collaborators of Jacob Selhub. A scholar is included among the top collaborators of Jacob Selhub based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jacob Selhub. Jacob Selhub is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Selhub, Jacob, et al.. (2024). A specific folate activates serotonergic neurons to control C. elegans behavior. Nature Communications. 15(1). 8471–8471. 1 indexed citations

Selhub, Jacob, et al.. (2024). Noncanonical function of folate through folate receptor 1 during neural tube formation. Nature Communications. 15(1). 8 indexed citations

McGowan, Emily C., Xiumei Hong, Jacob Selhub, et al.. (2018). The Association Between Folate/Folic Acid Metabolites and the Development of Food Allergy (FA) in Children. Journal of Allergy and Clinical Immunology. 141(2). AB86–AB86. 2 indexed citations

Scott, Tammy, Daniel E. Weiner, Kara A. Livingston, et al.. (2017). B-VITAMIN THERAPY FOR KIDNEY TRANSPLANT RECIPIENTS LOWERS HOMOCYSTEINE AND IMPROVES SELECTIVE COGNITIVE OUTCOMES IN THE RANDOMIZED FAVORIT ANCILLARY COGNITIVE TRIAL. The Journal of Prevention of Alzheimer s Disease. 4(3). 1–8. 12 indexed citations

Stolzenberg‐Solomon, Rachael Z., Stephanie J. Weinstein, Jacob Selhub, et al.. (2017). Low vitamin B-12 increases risk of gastric cancer: A prospective study of one-carbon metabolism nutrients and risk of upper gastrointestinal tract cancer. PubMed Central. 12 indexed citations

Sparks, Jeffrey A., Medha Barbhaiya, Elizabeth W. Karlson, et al.. (2017). Investigating methotrexate toxicity within a randomized double-blinded, placebo-controlled trial: Rationale and design of the Cardiovascular Inflammation Reduction Trial-Adverse Events (CIRT-AE) Study. Seminars in Arthritis and Rheumatism. 47(1). 133–142. 29 indexed citations

Jacques, Paul F., et al.. (2015). Xanthurenic acid is associated with higher insulin resistance and higher odds of diabetes. The FASEB Journal. 29. 9 indexed citations

Han, Summer S., Laura Y. Sue, Sonja I. Berndt, et al.. (2012). Associations between Genes in the One-Carbon Metabolism Pathway and Advanced Colorectal Adenoma Risk in Individuals with Low Folate Intake. Cancer Epidemiology Biomarkers & Prevention. 21(3). 417–427. 16 indexed citations

Wilson, Peter W.F., Michael Pencina, Paul F. Jacques, et al.. (2008). C-Reactive Protein and Reclassification of Cardiovascular Risk in the Framingham Heart Study. Circulation Cardiovascular Quality and Outcomes. 1(2). 92–97. 218 indexed citations

10.

Hodis, Howard N., Wendy J. Mack, Peter R. Mahrer, et al.. (2008). High-Dose B Vitamin Supplementation and Progression of Subclinical Atherosclerosis. Stroke. 40(3). 730–736. 102 indexed citations

11.

Selhub, Jacob, Paul F. Jacques, Gerard E. Dallal, Silvina F. Choumenkovitch, & Gail Rogers. (2008). The use of Blood Concentrations of Vitamins and their Respective Functional Indicators to Define Folate and Vitamin B₁₂ Status. Food and Nutrition Bulletin. 29(2_suppl1). S67–S73. 114 indexed citations

12.

Choumenkovitch, Silvina F., et al.. (2008). Circulating folic acid in plasma: relation to folic acid fortification. American Journal of Clinical Nutrition. 88(3). 763–768. 101 indexed citations

13.

Mason, Joel B., Aaron Dickstein, Paul F. Jacques, et al.. (2007). A Temporal Association between Folic Acid Fortification and an Increase in Colorectal Cancer Rates May Be Illuminating Important Biological Principles: A Hypothesis. Cancer Epidemiology Biomarkers & Prevention. 16(7). 1325–1329. 325 indexed citations

14.

Lee, I‐Min, Nancy R. Cook, Jacob Selhub, et al.. (2007). Plasma folate, vitamin B6, vitamin B12 and risk of breast cancer in women. Cancer Research. 67. 860–860. 3 indexed citations

15.

Ronnenberg, Alayne G., Marlene Goldman, Dafang Chen, et al.. (2002). Preconception Folate and Vitamin B6 Status and Clinical Spontaneous Abortion in Chinese Women. Obstetrics and Gynecology. 100(1). 107–113. 9 indexed citations

16.

Ghandour, Haifa, Bi‐Fong Lin, Joel B. Mason, Jacob Selhub, & Sang‐Woon Choi. (2002). Folate Status and Age Affect the Accumulation of l-Isoaspartyl Residues in Rat Liver Proteins. Journal of Nutrition. 132(6). 1357–1360. 20 indexed citations

17.

Selhub, Jacob. (2000). Folate, vitamin B12 and Vitamin B6 and One Carbon Metabolism. 35(6). 339–340. 251 indexed citations

18.

Lussier‐Cacan, Suzanne, et al.. (1995). Homocysteine and coronary artery disease in French Canadian subjects: Relation with vitamins B12, B6, pyridoxal phosphate, and folate. The American Journal of Cardiology. 75(16). 1107–1111. 151 indexed citations

19.

Kim, Young‐In, Anna R. Giuliano, Kenneth D. Hatch, et al.. (1994). Global DNA hypomethylation increases progressively in cervical dysplasia and carcinoma. Cancer. 74(3). 893–899. 146 indexed citations

20.

Russell, Robert M., et al.. (1991). Total homocysteine in fasting plasma is not a good indicator of b6 deficiency. The FASEB Journal. 5(4). 557. 5 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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