Hehua Lei

1.9k total citations · 1 hit paper
55 papers, 1.5k citations indexed

About

Hehua Lei is a scholar working on Molecular Biology, Epidemiology and Oceanography. According to data from OpenAlex, Hehua Lei has authored 55 papers receiving a total of 1.5k indexed citations (citations by other indexed papers that have themselves been cited), including 30 papers in Molecular Biology, 9 papers in Epidemiology and 7 papers in Oceanography. Recurrent topics in Hehua Lei's work include Metabolomics and Mass Spectrometry Studies (18 papers), Gut microbiota and health (11 papers) and Aquatic Ecosystems and Phytoplankton Dynamics (7 papers). Hehua Lei is often cited by papers focused on Metabolomics and Mass Spectrometry Studies (18 papers), Gut microbiota and health (11 papers) and Aquatic Ecosystems and Phytoplankton Dynamics (7 papers). Hehua Lei collaborates with scholars based in China, Singapore and United States. Hehua Lei's co-authors include Huiru Tang, Yulan Wang, Limin Zhang, Ping Xie, Fuhua Hao, Chuan Chen, Zheng Cao, Gui Chen, Gaodao Liang and Jun Chen and has published in prestigious journals such as The Science of The Total Environment, Journal of Hazardous Materials and Journal of Agricultural and Food Chemistry.

In The Last Decade

Hehua Lei

54 papers receiving 1.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Microbial Tryptophan Metabolites Ameliorate Ovariectomy‐Induced Bone Loss by Repairing Intestinal AhR‐Mediated Gut‐Bone Signaling Pathway

2024 44 citations Chuan Chen, Zheng Cao et al. Advanced Science profile →

Peers

Hehua Lei

PHYSI

EPIDE

OCEAN

Zdeněk Spáčil Czechia

Tomoyuki Koyama Japan

Alejandro M. S. Mayer United States

Hyukjae Choi South Korea

Naohisa Ishikawa Japan

Benjamin H. Maskrey United Kingdom

Alain Paris France

Junichi Maruyama Japan

Michael Witting Germany

Zdeněk Spáčil Czechia

Hehua Lei

651 ×0.9

163 ×0.6

340 ×1.4

PHYSI

112 ×0.5

EPIDE

61 ×0.4

OCEAN

Citations per year, relative to Hehua Lei Hehua Lei (= 1×) peers Zdeněk Spáčil

Countries citing papers authored by Hehua Lei

Since Specialization

Citations

This map shows the geographic impact of Hehua Lei's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hehua Lei with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hehua Lei more than expected).

Fields of papers citing papers by Hehua Lei

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hehua Lei. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hehua Lei. The network helps show where Hehua Lei may publish in the future.

Co-authorship network of co-authors of Hehua Lei

This figure shows the co-authorship network connecting the top 25 collaborators of Hehua Lei. A scholar is included among the top collaborators of Hehua Lei based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hehua Lei. Hehua Lei is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Cao, Zheng, Cui Zhang, Hehua Lei, et al.. (2025). Lactobacillus Salivarius ‐Derived Indole‐3‐Acetic Acid Promotes AHR‐PARP1 Axis‐Mediated DNA Repair to Mitigate Intestinal Aging. Advanced Science. 13(4). e15794–e15794.

Cao, Zheng, Cui Zhang, Lijun Liu, et al.. (2025). Microbiota-derived indole acetic acid extends lifespan through the AhR-Sirt2 pathway in Drosophila. mSystems. 10(5). e0166524–e0166524. 1 indexed citations

Chen, Chuan, Zheng Cao, Hehua Lei, et al.. (2024). Microbial Tryptophan Metabolites Ameliorate Ovariectomy‐Induced Bone Loss by Repairing Intestinal AhR‐Mediated Gut‐Bone Signaling Pathway. Advanced Science. 11(36). e2404545–e2404545. 44 indexed citations breakdown →

Chen, Yujie, Hehua Lei, Zheng Cao, et al.. (2024). In vivo and in vitro insights into the anti-hyperuricemic effects of sacha inchi (plukenetia volubilis l.) leaves extract rich in polyphenols. Food Bioscience. 59. 103864–103864. 5 indexed citations

Lei, Hehua, Yuchen Song, Mengjing Wu, et al.. (2023). Triclocarban exposure aggravates dextran sulfate sodium-induced colitis by deteriorating the gut barrier function and microbial community in mice. Food and Chemical Toxicology. 178. 113908–113908. 5 indexed citations

Zhang, Cui, Zheng Cao, Hehua Lei, et al.. (2023). Discovery of a novel small molecule with efficacy in protecting against inflammation in vitro and in vivo by enhancing macrophages activation. Biomedicine & Pharmacotherapy. 165. 115273–115273. 8 indexed citations

Chen, Chuan, Mengjing Wu, Hehua Lei, et al.. (2023). A Novel Prenylflavonoid Icariside I Ameliorates Estrogen Deficiency-Induced Osteoporosis via Simultaneous Regulation of Osteoblast and Osteoclast Differentiation. ACS Pharmacology & Translational Science. 6(2). 270–280. 13 indexed citations

Zhang, Ce, Zunji Shi, Hehua Lei, et al.. (2023). Dietary Isoquercetin Reduces Hepatic Cholesterol and Triglyceride in NAFLD Mice by Modulating Bile Acid Metabolism via Intestinal FXR-FGF15 Signaling. Journal of Agricultural and Food Chemistry. 71(20). 7723–7733. 23 indexed citations

Lei, Hehua, Zheng Cao, Chuan Chen, et al.. (2023). Multiomics analyses reveal dose-dependent effects of dicofol exposure on host metabolic homeostasis and the gut microbiota in mice. Chemosphere. 341. 139997–139997. 2 indexed citations

10.

Shi, Zunji, Ce Zhang, Hehua Lei, et al.. (2022). Structural Insights into Amelioration Effects of Quercetin and Its Glycoside Derivatives on NAFLD in Mice by Modulating the Gut Microbiota and Host Metabolism. Journal of Agricultural and Food Chemistry. 70(46). 14732–14743. 32 indexed citations

11.

Wu, Fang, Hehua Lei, Gui Chen, et al.. (2022). Multiomics Analyses Reveal That Long-Term Intake of Hesperetin-7-O-glucoside Modulates the Gut Microbiota and Bile Acid Metabolism in Mice. Journal of Agricultural and Food Chemistry. 70(47). 14831–14840. 8 indexed citations

12.

Shi, Zunji, Hehua Lei, Gui Chen, et al.. (2021). Impaired Intestinal Akkermansia muciniphila and Aryl Hydrocarbon Receptor Ligands Contribute to Nonalcoholic Fatty Liver Disease in Mice. mSystems. 6(1). 52 indexed citations

13.

Lei, Hehua, Yuchen Song, Gui Chen, et al.. (2021). Metabolomics safety assessments of microcystin exposure via drinking water in rats. Ecotoxicology and Environmental Safety. 212. 111989–111989. 12 indexed citations

14.

Sun, Yuting, Peihong Yuan, Hehua Lei, et al.. (2021). Quantitative structure-retention relationship for reliable metabolite identification and quantification in metabolomics using ion-pair reversed-phase chromatography coupled with tandem mass spectrometry. Talanta. 238(Pt 2). 123059–123059. 23 indexed citations

15.

Wu, Fang, Hehua Lei, Gui Chen, et al.. (2021). In Vitro and In Vivo Studies Reveal that Hesperetin-7-O-glucoside, a Naturally Occurring Monoglucoside, Exhibits Strong Anti-inflammatory Capacity. Journal of Agricultural and Food Chemistry. 69(43). 12753–12762. 41 indexed citations

16.

Shi, Zunji, Gui Chen, Zheng Cao, et al.. (2021). Gut Microbiota and Its Metabolite Deoxycholic Acid Contribute to Sucralose Consumption-Induced Nonalcoholic Fatty Liver Disease. Journal of Agricultural and Food Chemistry. 69(13). 3982–3991. 30 indexed citations

17.

Yuan, Peihong, et al.. (2021). Long-term chronic exposure to di-(2-ethylhexyl)-phthalate induces obesity via disruption of host lipid metabolism and gut microbiota in mice. Chemosphere. 287(Pt 4). 132414–132414. 42 indexed citations

18.

Wu, Fang, Zunji Shi, Hehua Lei, et al.. (2020). Short-Term Intake of Hesperetin-7-O-Glucoside Affects Fecal Microbiota and Host Metabolic Homeostasis in Mice. Journal of Agricultural and Food Chemistry. 69(5). 1478–1486. 11 indexed citations

19.

Xu, Xiaoyi, Qingxia Huang, Hehua Lei, et al.. (2019). Dose-Dependent Effects of Triclocarban Exposure on Lipid Homeostasis in Rats. Chemical Research in Toxicology. 32(11). 2320–2328. 22 indexed citations

20.

Jiang, Limiao, Xiu‐Ju Zhao, Chongyang Huang, et al.. (2014). Dynamic changes in metabolic profiles of rats subchronically exposed to mequindox. Molecular BioSystems. 10(11). 2914–2922. 8 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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