Gu He

8.9k citations

243 papers · 6.8k indexed · 2 hit papers · h-index 44

Impact in

Organic Chemistry top 1%
- Asymmetric Synthesis and Catalysis
- Catalytic C–H Functionalization Methods
- Synthetic Organic Chemistry Methods
Dermatology top 1%

Papers in ⓘ

Molecular Biology 125
- RNA Interference and Gene Delivery 18
- Chemical Synthesis and Analysis 16
- Protein Degradation and Inhibitors 14
Organic Chemistry 51
- Asymmetric Synthesis and Catalysis 14
- Synthetic Organic Chemistry Methods 11

Co-authors: Bo Han (37 shared papers)Cheng Peng (34 shared papers)Wei Huang (37 shared papers)Xian Jiang (26 shared papers)Xiang Wen (16 shared papers)Liang Ouyang (26 shared papers)Bo Liu (11 shared papers)Dan Hao (8 shared papers)
Journals: European Journal of Medicinal Chemistry (10 papers)Journal of Medicinal Chemistry (9 papers)International Journal of Molecular Sciences (5 papers)Organic Letters (5 papers)Frontiers in Immunology (5 papers)
Partner nations: China United States Japan

In The Last Decade

Gu He

234 papers receiving 6.7k citations

Hit Papers

align trajectories log scale

Recent advances in targeting the “undruggable” proteins: from drug discovery to clinical trials 2023 · 188 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2023 Signal Transduction and Targeted Therapy
2021 Chemical Society Reviews

Peers

Countries citing papers authored by Gu He

Since Specialization

Citations

This map shows the geographic impact of Gu He's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Gu He with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Gu He more than expected).

Fields of papers citing papers by Gu He

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Gu He. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Gu He. The network helps show where Gu He may publish in the future.

Co-authors

The 25 scholars most cited alongside Gu He, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Gu He Line = papers co-authored together Gu He links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 243 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Asymmetric organocatalysis: an enabling technology for medicinal chemistry Chemical Society Reviews ·Bo Han, Xiang‐Hong He, Yanqing Liu, Gu He, Cheng Peng, Jun‐Long Li Hit paper breakdown →	2021	306
2	From pathogenesis of acne vulgaris to anti-acne agents Archives of Dermatological Research ·Tianxin Cong, Dan Hao, Xiang Wen, Xiaohua Li, Gu He, Xian Jiang	2019	201
3	Recent advances in targeting the “undruggable” proteins: from drug discovery to clinical trials Signal Transduction and Targeted Therapy ·Xin Xie, Tingting Yu, Xiang Li, Nan Zhang, Leonard J. Foster, Cheng Peng, Wei Huang, Gu He Hit paper breakdown →	2023	188
4	Reversion of multidrug resistance by co-encapsulation of vincristine and verapamil in PLGA nanoparticles European Journal of Pharmaceutical Sciences ·Xiang Song, Zheng Cai, Yu Zheng, Gu He, Feng Yu Cui, Dao Qiong Gong, Shi Hou, Si Jing Xiong, Xiang Jie Lei, Yu Wei	2009	172
5	Protein SUMOylation modification and its associations with disease Open Biology ·Yanfang Yang, Yu He, Xixi Wang, Ziwei Liang, Gu He, Peng Zhang, Hongxia Zhu, Ningzhi Xu, (unknown)	2017	161
6	NF-κB signaling in skin aging Mechanisms of Ageing and Development ·Yujia Wang, Lian Wang, Xiang Wen, Dan Hao, Nan Zhang, Gu He, Xian Jiang	2019	154
7	Targeting Programmed Cell Death Using Small‐Molecule Compounds to Improve Potential Cancer Therapy Medicinal Research Reviews ·Bowen Ke, Mao Tian, Jingjing Li, Bo Liu, Gu He	2016	151
8	COF-Based Composites: Extraordinary Removal Performance for Heavy Metals and Radionuclides from Aqueous Solutions Reviews of Environmental Contamination and Toxicology ·Gu He, Xiaolu Liu, Suhua Wang, Zhongshan Chen, Hui Yang, Baowei Hu, Chi Shen, Xiangke Wang	2022	130
9	Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo Chemical Science ·Lan Zhang, Leilei Fu, Shouyue Zhang, Jin Zhang, Yuqian Zhao, Yaxin Zheng, Gu He, Shengyong Yang, Liang Ouyang, Bo Liu	2017	123
10	Asymmetric Synthesis of Cyclohexane‐Fused Drug‐Like Spirocyclic Scaffolds Containing Six Contiguous Stereogenic Centers via Organocatalytic Cascade Reactions Advanced Synthesis & Catalysis ·Bo Han, Wei Huang, Wen Ren, Gu He, Jin‐hui Wang, Cheng Peng	2015	113
11	In Vitro and In Vivo Activities of Antimicrobial Peptides Developed Using an Amino Acid-Based Activity Prediction Method Antimicrobial Agents and Chemotherapy ·Xiaozhe Wu, Zhenling Wang, Xiaolu Li, Yingzi Fan, Gu He, Yang Wan, Chaoheng Yu, Jianying Tang, Meng Li, Xian Zhang, Hailong Zhang, Rong Xiang, Ying Pan, Yan Liu, Lian Lu, Li Yang	2014	91
12	Development of glycyrrhetinic acid-modified stealth cationic liposomes for gene delivery International Journal of Pharmaceutics ·Zhiyao He, Xi Zheng, Xiao Wu, Xiang Song, Gu He, Wen Fang Wu, Shui Yu, Sheng Mao, Yu Wei	2010	83
13	Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer Journal of Medicinal Chemistry ·Liang Ouyang, Lan Zhang, Jie Liu, Leilei Fu, Dahong Yao, Yuqian Zhao, Shouyue Zhang, Guan Wang, Gu He, Bo Liu	2017	81
14	Organocatalytic Asymmetric Synthesis of Spiro-oxindole Piperidine Derivatives That Reduce Cancer Cell Proliferation by Inhibiting MDM2–p53 Interaction Organic Letters ·Ming-Cheng Yang, Cheng Peng, Hua Huang, Lei Yang, Xiang‐Hong He, Wei Huang, Hai‐Lei Cui, Gu He, Bo Han	2017	81
15	Organocatalytic cascade reaction for the asymmetric synthesis of novel chroman-fused spirooxindoles that potently inhibit cancer cell proliferation Chemical Communications ·Rui Zhou, Qinjie Wu, Mingrui Guo, Wei Huang, Xiang‐Hong He, Lei Yang, Peng Fu, Gu He, Bo Han	2015	76
16	Sanshool improves UVB-induced skin photodamage by targeting JAK2/STAT3-dependent autophagy Cell Death and Disease ·Dan Hao, Xiang Wen, Lian Liu, Lian Wang, Xian‐Li Zhou, Yanmei Li, Xin Zeng, Gu He, Xian Jiang	2019	74
17	Mechanisms of PANoptosis and relevant small-molecule compounds for fighting diseases Cell Death and Disease ·Lian Wang, Yanghui Zhu, Lu Zhang, Linghong Guo, Xiaoyun Wang, Zhaoping Pan, Xian Jiang, Fengbo Wu, Gu He	2023	73
18	Development of PLGA Nanoparticles Simultaneously Loaded with Vincristine and Verapamil for Treatment of Hepatocellular Carcinoma Journal of Pharmaceutical Sciences ·Xiang Song, Yu Zheng, Yu Zheng, Gu He, Yang Li, Y. Luo, Zhiyao He, Shuang Zhi Li, Jun Ming Li, Shui Yu, Xun Luo, Shi Hou, Yu Wei	2010	68
19	Discovery of Thieno[2,3-d]pyrimidine-Based Hydroxamic Acid Derivatives as Bromodomain-Containing Protein 4/Histone Deacetylase Dual Inhibitors Induce Autophagic Cell Death in Colorectal Carcinoma Cells Journal of Medicinal Chemistry ·Zhaoping Pan, Xiang Li, Yujia Wang, Qinglin Jiang, Li Jiang, Min Zhang, Nan Zhang, Fengbo Wu, Bo Liu, Gu He	2020	68
20	Asymmetric synthesis of a structurally and stereochemically complex spirooxindole pyran scaffold through an organocatalytic multicomponent cascade reaction Chemical Communications ·Xin Xie, Cheng Peng, Gu He, Hai‐Jun Leng, Biao Wang, Wei Huang, Bo Han	2012	67

About Gu He

Gu He is a scholar working on Molecular Biology, Organic Chemistry, Cancer Research, Endocrine and Autonomic Systems and Biomaterials, having authored 243 papers that have together received 6.8k indexed citations. Recurring topics across this work include RNA Interference and Gene Delivery (18 papers), Chemical Synthesis and Analysis (16 papers), Nanoparticle-Based Drug Delivery (14 papers), Autophagy in Disease and Therapy (14 papers), Asymmetric Synthesis and Catalysis (14 papers), Protein Degradation and Inhibitors (14 papers), Computational Drug Discovery Methods (13 papers) and Synthetic Organic Chemistry Methods (11 papers). The work is most often cited by research in Organic Chemistry (1.7k citations), Dermatology (444 citations), Molecular Biology (3.0k citations), Biomaterials (563 citations) and Pharmaceutical Science (239 citations). Gu He has collaborated with scholars based in China, United States and Japan. Frequent co-authors include Bo Han, Cheng Peng, Wei Huang, Xian Jiang, Xiang Wen, Liang Ouyang, Bo Liu, Dan Hao, Fengbo Wu and Lian Wang. Their work appears in journals such as European Journal of Medicinal Chemistry, Journal of Medicinal Chemistry, International Journal of Molecular Sciences, Organic Letters and Frontiers in Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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