Gerard Clarke

45.8k total citations · 21 hit papers
270 papers, 28.0k citations indexed

About

Gerard Clarke is a scholar working on Molecular Biology, Biological Psychiatry and Physiology. According to data from OpenAlex, Gerard Clarke has authored 270 papers receiving a total of 28.0k indexed citations (citations by other indexed papers that have themselves been cited), including 150 papers in Molecular Biology, 107 papers in Biological Psychiatry and 72 papers in Physiology. Recurrent topics in Gerard Clarke's work include Gut microbiota and health (140 papers), Tryptophan and brain disorders (107 papers) and Diet and metabolism studies (59 papers). Gerard Clarke is often cited by papers focused on Gut microbiota and health (140 papers), Tryptophan and brain disorders (107 papers) and Diet and metabolism studies (59 papers). Gerard Clarke collaborates with scholars based in Ireland, United States and United Kingdom. Gerard Clarke's co-authors include John F. Cryan, Timothy G. Dinan, Catherine Stanton, Paul J. Kennedy, Yuliya Borre, Siobhain M. O’Mahony, Rachel D. Moloney, Lieve Desbonnet, Fergus Shanahan and Roman M. Stilling and has published in prestigious journals such as Journal of Clinical Investigation, Nature Communications and SHILAP Revista de lepidopterología.

In The Last Decade

Gerard Clarke

262 papers receiving 27.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner

2012 1.4k citations Gerard Clarke, Fergus Shanahan et al. Molecular Psychiatry profile →
Serotonin, tryptophan metabolism and the brain-gut-microbiome axis

2014 1.4k citations Siobhain M. O’Mahony, Gerard Clarke et al. profile →
Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat

2016 1.2k citations Karen A. Scott, Gerard M. Moloney et al. profile →
Minireview: Gut Microbiota: The Neglected Endocrine Organ

2014 876 citations Gerard Clarke, Roman M. Stilling et al. profile →
Microbiota and neurodevelopmental windows: implications for brain disorders

2014 816 citations Gerard W. O’Keeffe, Gerard Clarke et al. profile →
Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders

2015 814 citations John F. Cryan, Timothy G. Dinan et al. profile →
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression

2010 753 citations Gerard Clarke, John F. Cryan et al. profile →
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat

2008 749 citations Gerard Clarke, Timothy G. Dinan et al. profile →
Brain?Gut?Microbe Communication in Health and Disease

2011 704 citations Gerard Clarke, John F. Cryan et al. profile →
Targeting the Microbiota-Gut-Brain Axis: Prebiotics Have Anxiolytic and Antidepressant-like Effects and Reverse the Impact of Chronic Stress in Mice

2017 704 citations Gerard Clarke, Catherine Stanton et al. profile →
The neuropharmacology of butyrate: The bread and butter of the microbiota-gut-brain axis?

2016 656 citations Roman M. Stilling, Marcel van de Wouw et al. profile →
Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour

2015 596 citations Gerard Clarke, Órla O’Sullivan et al. profile →
Short‐chain fatty acids: microbial metabolites that alleviate stress‐induced brain–gut axis alterations

2018 571 citations Marcel van de Wouw, Marcus Boehme et al. The Journal of Physiology profile →
Biological and psychological markers of stress in humans: Focus on the Trier Social Stress Test

2013 563 citations Andrew Allen, John F. Cryan et al. Neuroscience & Biobehavioral Reviews profile →
Kynurenine pathway metabolism and the microbiota-gut-brain axis

2016 509 citations John F. Cryan, Gerard Clarke et al. Neuropharmacology profile →
Growing up in a Bubble: Using Germ-Free Animals to Assess the Influence of the Gut Microbiota on Brain and Behavior

2016 453 citations Gerard Clarke, Timothy G. Dinan et al. profile →
The blood-brain barrier in aging and neurodegeneration

2022 416 citations Emily G. Knox, María R. Aburto et al. Molecular Psychiatry profile →
Short chain fatty acids: Microbial metabolites for gut-brain axis signalling

2022 402 citations Kenneth J. O’Riordan, Michael Collins et al. profile →
Feeding gut microbes to nourish the brain: unravelling the diet–microbiota–gut–brain axis

2024 76 citations Kenneth J. O’Riordan, Gerard Clarke et al. profile →
The gut microbiota-immune-brain axis: Therapeutic implications

2025 61 citations Kenneth J. O’Riordan, Gerard M. Moloney et al. profile →
Gut microbiota regulates stress responsivity via the circadian system

2024 55 citations Sarah‐Jane Leigh, Cassandra E. Gheorghe et al. profile →

Peers

Countries citing papers authored by Gerard Clarke

Since Specialization

Citations

This map shows the geographic impact of Gerard Clarke's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Gerard Clarke with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Gerard Clarke more than expected).

Fields of papers citing papers by Gerard Clarke

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Gerard Clarke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Gerard Clarke. The network helps show where Gerard Clarke may publish in the future.

Co-authorship network of co-authors of Gerard Clarke

This figure shows the co-authorship network connecting the top 25 collaborators of Gerard Clarke. A scholar is included among the top collaborators of Gerard Clarke based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Gerard Clarke. Gerard Clarke is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Acute stress enhances synaptic plasticity in male mice via a microbiota-dependent mechanism 2025 ·Neuropharmacology ·(unknown), Michael Collins, Kenneth J. O’Riordan, Michael S. Goodson, Nancy Kelley‐Loughnane, John F. Cryan, Gerard Clarke	4
2	I "Gut" Rhythm: the microbiota as a modulator of the stress response and circadian rhythms 2025 ·FEBS Journal ·(unknown), Gerard Clarke, John F. Cryan	1
3	In vitro assessment of bacterial supernatants on hypothalamic gene expression: implications for appetite regulation 2025 ·npj Biofilms and Microbiomes ·(unknown), (unknown), Thomaz F. S. Bastiaanssen, John F. Cryan, Catherine Stanton, Siobhain M. O’Mahony, Gerard Clarke, Harriët Schellekens	0
4	Acute stress-induced alterations in short-chain fatty acids: Implications for the intestinal and blood brain barriers 2025 ·Brain Behavior & Immunity - Health ·(unknown), Sarah‐Jane Leigh, Emily G. Knox, (unknown), Joshua M. Lyte, Michael S. Goodson, Nancy Kelley‐Loughnane, María R. Aburto, John F. Cryan, Gerard Clarke	3
5	Sex specific gut-microbiota signatures of resilient and comorbid gut-brain phenotypes induced by early life stress 2024 ·Neurobiology of Stress ·(unknown), (unknown), Thomaz F. S. Bastiaanssen, James M. Collins, Fiona Crispie, Paul D. Cotter, Timothy G. Dinan, John F. Cryan, Gerard Clarke, Siobhain M. O’Mahony	5
6	Microbiota-gut-brain axis in binge-eating disorder: Towards microbiome-based therapies 2024 ·Neuroscience Applied ·Elizabeth M. Schneider, Sarah‐Jane Leigh, C. M. Lynch, Anja Hilbert, Gerard Clarke, Suzanne Higgs, John F. Cryan	1
7	Prenatal stress impacts foetal neurodevelopment: Temporal windows of gestational vulnerability 2024 ·Neuroscience & Biobehavioral Reviews ·James M. Collins, James Keane, (unknown), Ali S. Khashan, Fergus P. McCarthy, Gerard W. O’Keeffe, Gerard Clarke, John F. Cryan, (unknown), Siobhain M. O’Mahony	10
8	Impact of dietary fiber on gut microbiota composition, function and gut-brain-modules in healthy adults – a systematic review protocol 2023 ·HRB Open Research ·(unknown), (unknown), Thomaz F. S. Bastiaanssen, John F. Cryan, Gerard Clarke, Aonghus Lavelle	2
9	The Stressed Gut: Region-specific Immune and Neuroplasticity Changes in Response to Chronic Psychosocial Stress 2023 ·Journal of Neurogastroenterology and Motility ·Beatriz Lobo, Mónica Tramullas, (unknown), Kevin W. Lomasney, Caroll J. Beltrán, Gerard Clarke, Javier Santos, Niall P. Hyland, Timothy G. Dinan, John F. Cryan	13
10	The Microbiome-Gut-Brain axis regulates social cognition & craving in young binge drinkers 2023 ·EBioMedicine ·Carina Carbia, Thomaz F. S. Bastiaanssen, Luigi Francesco Iannone, (unknown), Serena Boscaini, Kirsten Berding, Conall Strain, Gerard Clarke, Catherine Stanton, Timothy G. Dinan, John F. Cryan	35
11	Feed your microbes to deal with stress: a psychobiotic diet impacts microbial stability and perceived stress in a healthy adult population 2022 ·Molecular Psychiatry ·Kirsten Berding, Thomaz F. S. Bastiaanssen, Gerard M. Moloney, Serena Boscaini, Conall Strain, Andrea Anesi, Caitríona M. Long-Smith, Fulvio Mattivi, Catherine Stanton, Gerard Clarke, Timothy G. Dinan, John F. Cryan	84
12	Cancer Immunotherapy with Immune Checkpoint Inhibitors-Biomarkers of Response and Toxicity; Current Limitations and Future Promise 2022 ·Diagnostics ·Brian Bird, Kenneth Nally, (unknown), Gerard Clarke, (unknown), Ana S. Almeida, Richard Flavin, Stephen P. Finn	11
13	Sex and brain region‐specific regulation of serotonin transporter activity in synaptosomes in guanine nucleotide‐binding protein G(q) alpha knockout mice 2021 ·Journal of Neurochemistry ·Jana Haase, (unknown), (unknown), Eric J. Brown, Gerard Clarke, Gudrun Ahnert‐Hilger	4
14	Guidelines for reporting on animal fecal transplantation (GRAFT) studies: recommendations from a systematic review of murine transplantation protocols 2021 ·Gut Microbes ·Kate R. Secombe, Ghanyah Al-Qadami, (unknown), Joanne M. Bowen, (unknown), Ysabella Van Sebille, Matthew Snelson, Caitlin S.M. Cowan, Gerard Clarke, Cassandra E. Gheorghe, John F. Cryan, Hannah R. Wardill	53
15	Improvements in sleep indices during exam stress due to consumption of a Bifidobacterium longum 2020 ·Brain Behavior & Immunity - Health ·Gerard M. Moloney, Caitríona M. Long-Smith, Amy Murphy, (unknown), (unknown), (unknown), David Campos, Thomaz F. S. Bastiaanssen, (unknown), Kirsten Berding, Fiona Fouhy, Andrew Allen, Catherine Stanton, Gerard Clarke, Timothy G. Dinan, John F. Cryan	47
16	Natural compulsive‐like behaviour in the deer mouse ( Peromyscus maniculatus bairdii ) is associated with altered gut microbiota composition 2019 ·European Journal of Neuroscience ·(unknown), John F. Cryan, Thomaz F. S. Bastiaanssen, Kieran Rea, Gerard Clarke, Heather B. Jaspan, Brian H. Harvey, Sian Hemmings, (unknown), Rencia van der Sluis, Stefanie Malan‐Müller, De Wet Wolmarans	30
17	Mid-life microbiota crises: middle age is associated with pervasive neuroimmune alterations that are reversed by targeting the gut microbiome 2019 ·Molecular Psychiatry ·Marcus Boehme, Marcel van de Wouw, Thomaz F. S. Bastiaanssen, Loreto Olavarría‐Ramírez, Katríona Lyons, Fiona Fouhy, Anna V. Golubeva, Gerard M. Moloney, (unknown), Kiran V. Sandhu, Karen A. Scott, Gerard Clarke, Catherine Stanton, Timothy G. Dinan, Harriët Schellekens, John F. Cryan	100
18	No effect of a musical intervention on stress response to venepuncture in a neonatal population 2019 ·Acta Paediatrica ·(unknown), (unknown), Elena Pavlidis, Andreea Pavel, (unknown), Andrew P. Allen, Loreto Olavarría‐Ramírez, Gerard Clarke, Vicki Livingstone, Geraldine B. Boylan, Eugene Dempsey	8
19	Social interaction-induced activation of RNA splicing in the amygdala of microbiome-deficient mice 2018 ·eLife ·Roman M. Stilling, Gerard M. Moloney, Feargal J. Ryan, Alan E. Hoban, Thomaz F. S. Bastiaanssen, Fergus Shanahan, Gerard Clarke, Marcus J. Claesson, Timothy G. Dinan, John F. Cryan	82
20	Short‐chain fatty acids: microbial metabolites that alleviate stress‐induced brain–gut axis alterations breakdown → 2018 ·The Journal of Physiology ·Marcel van de Wouw, Marcus Boehme, Joshua M. Lyte, Niamh Wiley, Conall Strain, Órla O’Sullivan, Gerard Clarke, Catherine Stanton, Timothy G. Dinan, John F. Cryan	571

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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