Gebhard Thoma

2.1k total citations
54 papers, 1.5k citations indexed

About

Gebhard Thoma is a scholar working on Molecular Biology, Organic Chemistry and Immunology and Allergy. According to data from OpenAlex, Gebhard Thoma has authored 54 papers receiving a total of 1.5k indexed citations (citations by other indexed papers that have themselves been cited), including 27 papers in Molecular Biology, 18 papers in Organic Chemistry and 15 papers in Immunology and Allergy. Recurrent topics in Gebhard Thoma's work include Cell Adhesion Molecules Research (14 papers), Glycosylation and Glycoproteins Research (12 papers) and Carbohydrate Chemistry and Synthesis (9 papers). Gebhard Thoma is often cited by papers focused on Cell Adhesion Molecules Research (14 papers), Glycosylation and Glycoproteins Research (12 papers) and Carbohydrate Chemistry and Synthesis (9 papers). Gebhard Thoma collaborates with scholars based in Switzerland, United States and Germany. Gebhard Thoma's co-authors include Hans‐Günter Zerwes, Rudolf O. Duthaler, Dennis P. Curran, John L. Magnani, John T. Patton, Markus Streiff, Bernd Giese, Andreas Katopodis, Peter Drückes and Beat Ernst and has published in prestigious journals such as Journal of the American Chemical Society, Angewandte Chemie International Edition and Journal of Clinical Investigation.

In The Last Decade

Gebhard Thoma

53 papers receiving 1.5k citations

Peers

Gebhard Thoma
Robert J. Slack United Kingdom
Clifford Quan United States
Wilson B. Knight United States
Roxana E. Iacob United States
Nouri Neamati United States
Miljenko Mervič United States
Julie L. Sutcliffe United States
Robert J. Slack United Kingdom
Gebhard Thoma
Citations per year, relative to Gebhard Thoma Gebhard Thoma (= 1×) peers Robert J. Slack

Countries citing papers authored by Gebhard Thoma

Since Specialization
Citations

This map shows the geographic impact of Gebhard Thoma's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Gebhard Thoma with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Gebhard Thoma more than expected).

Fields of papers citing papers by Gebhard Thoma

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Gebhard Thoma. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Gebhard Thoma. The network helps show where Gebhard Thoma may publish in the future.

Co-authorship network of co-authors of Gebhard Thoma

This figure shows the co-authorship network connecting the top 25 collaborators of Gebhard Thoma. A scholar is included among the top collaborators of Gebhard Thoma based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Gebhard Thoma. Gebhard Thoma is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Loesche, Christian, D Picard, Gebhard Thoma, et al.. (2024). LTA4H inhibitor LYS006: Clinical PK/PD and safety in a randomized phase I clinical trial. Clinical and Translational Science. 17(2). e13724–e13724. 2 indexed citations
2.
Thoma, Gebhard, Rudolf O. Duthaler, Rudolf Waelchli, et al.. (2023). Discovery and Characterization of the Topical Soft JAK Inhibitor CEE321 for Atopic Dermatitis. Journal of Medicinal Chemistry. 66(3). 2161–2168. 11 indexed citations
3.
Thoma, Gebhard, Christian Märkert, Wolfgang Miltz, et al.. (2023). Discovery of Amino Alcohols as Highly Potent, Selective, and Orally Efficacious Inhibitors of Leukotriene A4 Hydrolase. Journal of Medicinal Chemistry. 66(23). 16410–16425. 3 indexed citations
4.
Thoma, Gebhard, et al.. (2023). Novel Concept for Super-Soft Topical Drugs: Deactivation by an Enzyme-Induced Switch into an Inactive Conformation. ACS Medicinal Chemistry Letters. 14(6). 841–845.
5.
Röhn, Till A., Shin Numao, H Otto, Christian Loesche, & Gebhard Thoma. (2021). Drug discovery strategies for novel leukotriene A4 hydrolase inhibitors. Expert Opinion on Drug Discovery. 16(12). 1483–1495. 14 indexed citations
6.
Thoma, Gebhard, Siem J. Veenstra, Joachim Blanz, et al.. (2015). Orally bioavailable Syk inhibitors with activity in a rat PK/PD model. Bioorganic & Medicinal Chemistry Letters. 25(20). 4642–4647. 6 indexed citations
7.
Thoma, Gebhard, Alexander B. Smith, Maurice J. van Eis, et al.. (2015). Discovery and Profiling of a Selective and Efficacious Syk Inhibitor. Journal of Medicinal Chemistry. 58(4). 1950–1963. 19 indexed citations
8.
Thoma, Gebhard, Joachim Blanz, Peter Bühlmayer, et al.. (2014). Syk inhibitors with high potency in presence of blood. Bioorganic & Medicinal Chemistry Letters. 24(10). 2278–2282. 17 indexed citations
9.
Thoma, Gebhard, Peter Drückes, & Hans‐Günter Zerwes. (2014). Selective inhibitors of the Janus kinase Jak3—Are they effective?. Bioorganic & Medicinal Chemistry Letters. 24(19). 4617–4621. 41 indexed citations
10.
Haan, Claude, Catherine Rolvering, Friedrich Raulf, et al.. (2011). Jak1 Has a Dominant Role over Jak3 in Signal Transduction through γc-Containing Cytokine Receptors. Chemistry & Biology. 18(3). 314–323. 154 indexed citations
11.
Duthaler, Rudolf O., Beat Ernst, Andreas Katopodis, et al.. (2010). In vivo Neutralization of Naturally Existing Antibodies against Linear ?(1,3)-Galactosidic Carbohydrate Epitopes by Multivalent Antigen Presentation: A Solution for the First Hurdle of Pig-to-Human Xenotransplantation. CHIMIA International Journal for Chemistry. 64(1-2). 23–23. 4 indexed citations
12.
Thoma, Gebhard, Christian Beerli, Marc Bigaud, et al.. (2008). Reduced cardiac side-effect potential by introduction of polar groups: Discovery of NIBR-1282, an orally bioavailable CCR5 antagonist which is active in vivo. Bioorganic & Medicinal Chemistry Letters. 18(6). 2000–2005. 9 indexed citations
13.
Zerwes, Hans‐Günter, Jiří Kovařík, Markus Streiff, et al.. (2008). The Chemokine Receptor Cxcr3 Is Not Essential for Acute Cardiac Allograft Rejection in Mice and Rats. American Journal of Transplantation. 8(8). 1604–1613. 28 indexed citations
14.
Thoma, Gebhard, Markus Streiff, Andreas Katopodis, et al.. (2005). Non‐Covalent Polyvalent Ligands by Self‐Assembly of Small Glycodendrimers: A Novel Concept for the Inhibition of Polyvalent Carbohydrate–Protein Interactions In Vitro and In Vivo. Chemistry - A European Journal. 12(1). 99–117. 31 indexed citations
15.
Biedermann, Tilo, Christoph Schwärzler, Günther Lametschwandtner, et al.. (2002). Targeting CLA/E-selectin interactions prevents CCR4-mediated recruitment of human Th2 memory cells to human skin in vivo. European Journal of Immunology. 32(11). 3171–3180. 81 indexed citations
16.
Katopodis, Andreas, Richard G. Warner, Rudolf O. Duthaler, et al.. (2002). Removal of anti-Galα1,3Gal xenoantibodies with an injectable polymer. Journal of Clinical Investigation. 110(12). 1869–1877. 67 indexed citations
17.
Thoma, Gebhard, et al.. (2001). A Readily Available, Highly Potent E-Selectin Antagonist. Angewandte Chemie International Edition. 40(19). 3644–3644. 24 indexed citations
18.
Thoma, Gebhard, John L. Magnani, & John T. Patton. (2001). Synthesis and biological evaluation of a sialyl lewis X mimic with significantly improved E-selectin inhibition. Bioorganic & Medicinal Chemistry Letters. 11(7). 923–925. 18 indexed citations
19.
Thoma, Gebhard, Rudolf O. Duthaler, John L. Magnani, & John T. Patton. (2001). Nanomolar E-Selectin Inhibitors:  700-Fold Potentiation of Affinity by Multivalent Ligand Presentation. Journal of the American Chemical Society. 123(41). 10113–10114. 37 indexed citations
20.
Norman, Keith E., Andreas Katopodis, Gebhard Thoma, et al.. (2000). P-selectin glycoprotein ligand-1 supports rolling on E- and P-selectin in vivo. Blood. 96(10). 3585–3591. 104 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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