Fraser P. Coxon

21.3k total citations · 5 hit papers
68 papers, 8.4k citations indexed

About

Fraser P. Coxon is a scholar working on Oncology, Molecular Biology and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Fraser P. Coxon has authored 68 papers receiving a total of 8.4k indexed citations (citations by other indexed papers that have themselves been cited), including 52 papers in Oncology, 45 papers in Molecular Biology and 17 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Fraser P. Coxon's work include Bone health and treatments (50 papers), Bone Metabolism and Diseases (27 papers) and Radiopharmaceutical Chemistry and Applications (14 papers). Fraser P. Coxon is often cited by papers focused on Bone health and treatments (50 papers), Bone Metabolism and Diseases (27 papers) and Radiopharmaceutical Chemistry and Applications (14 papers). Fraser P. Coxon collaborates with scholars based in United Kingdom, United States and Poland. Fraser P. Coxon's co-authors include Michael J. Rogers, Steven P. Luckman, R.G.G. Russell, Frank H. Ebetino, Jukka Mönkkönen, Keith Thompson, Miep Helfrich, Helena L. Benford, Julie C. Frith and Julie C. Crockett and has published in prestigious journals such as Journal of Biological Chemistry, Journal of Clinical Investigation and Molecular Cell.

In The Last Decade

Fraser P. Coxon

68 papers receiving 8.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Nitrogen-Containing Bisphosphonates Inhibit the Mevalonate Pathway and Prevent Post-Translational Prenylation of GTP-Binding Proteins, Including Ras

1998 977 citations Steven P. Luckman, Fraser P. Coxon et al. profile →
Structure-Activity Relationships for Inhibition of Farnesyl Diphosphate Synthase in Vitro and Inhibition of Bone Resorption in Vivo by Nitrogen-Containing Bisphosphonates

2001 726 citations James E. Dunford, Keith Thompson et al. profile →
Cellular and molecular mechanisms of action of bisphosphonates

2000 720 citations Michael J. Rogers, Sharon Gordon et al. Cancer profile →
Cellular and molecular mechanisms of action of bisphosphonates

2000 571 citations Michael J. Rogers, Sharon Gordon et al. Cancer profile →
PLEKHM1 Regulates Autophagosome-Lysosome Fusion through HOPS Complex and LC3/GABARAP Proteins

2014 431 citations David G. McEwan, Doris Popovic et al. Molecular Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Fraser P. Coxon United Kingdom	35	5.7k	3.5k	2.9k	1.4k	831	68	8.4k
William C. Dougall United States	45	6.5k 1.1×	6.6k 1.9×	1.1k 0.4×	883 0.6×	756 0.9×	94	10.5k
Philippe Clézardin France	59	5.8k 1.0×	4.7k 1.3×	1.0k 0.4×	2.0k 1.4×	583 0.7×	188	10.6k
Jean‐Marie Delaissé Denmark	55	4.0k 0.7×	5.4k 1.5×	1.8k 0.6×	439 0.3×	2.0k 2.5×	147	9.7k
Gabri van der Pluijm Netherlands	48	3.5k 0.6×	3.5k 1.0×	554 0.2×	845 0.6×	438 0.5×	129	7.0k
Françoise Rédiní France	48	3.0k 0.5×	4.1k 1.2×	714 0.2×	327 0.2×	1.5k 1.9×	181	7.9k
R. Felix Switzerland	34	2.2k 0.4×	2.6k 0.7×	760 0.3×	297 0.2×	606 0.7×	77	4.6k
Takuhiko Akatsu Japan	32	3.4k 0.6×	4.5k 1.3×	1.1k 0.4×	151 0.1×	932 1.1×	54	6.3k
Gregg Wesolowski United States	29	1.7k 0.3×	2.3k 0.7×	874 0.3×	256 0.2×	1.4k 1.6×	49	4.5k
K. Fuller United Kingdom	40	2.8k 0.5×	4.2k 1.2×	1.2k 0.4×	151 0.1×	979 1.2×	65	6.1k
Yao Wang China	40	4.9k 0.9×	2.7k 0.8×	602 0.2×	202 0.1×	103 0.1×	217	8.4k

Countries citing papers authored by Fraser P. Coxon

Since Specialization

Citations

This map shows the geographic impact of Fraser P. Coxon's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Fraser P. Coxon with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Fraser P. Coxon more than expected).

Fields of papers citing papers by Fraser P. Coxon

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Fraser P. Coxon. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Fraser P. Coxon. The network helps show where Fraser P. Coxon may publish in the future.

Co-authorship network of co-authors of Fraser P. Coxon

This figure shows the co-authorship network connecting the top 25 collaborators of Fraser P. Coxon. A scholar is included among the top collaborators of Fraser P. Coxon based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Fraser P. Coxon. Fraser P. Coxon is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Whyte, Claire S., et al.. (2023). Atorvastatin-mediated inhibition of prenylation of Rab27b and Rap1a in platelets attenuates their prothrombotic capacity and modulates clot structure. Platelets. 34(1). 2206921–2206921. 6 indexed citations

McEwan, David G., Doris Popovic, Andrea Gubaš, et al.. (2014). PLEKHM1 Regulates Autophagosome-Lysosome Fusion through HOPS Complex and LC3/GABARAP Proteins. Molecular Cell. 57(1). 39–54. 431 indexed citations breakdown →

Coxon, Fraser P., et al.. (2014). Synthesis and characterization of novel phosphonocarboxylate inhibitors of RGGT. European Journal of Medicinal Chemistry. 84. 77–89. 23 indexed citations

Vermeer, Jenny A. F., Ineke D.C. Jansen, Fraser P. Coxon, et al.. (2013). Jaw bone marrow-derived osteoclast precursors internalize more bisphosphonate than long-bone marrow precursors. Bone. 57(1). 242–251. 37 indexed citations

Itzstein, Cécile, Fraser P. Coxon, & Michael J. Rogers. (2011). The regulation of osteoclast function and bone resorption by small GTPases. Small GTPases. 2(3). 117–130. 119 indexed citations

Henriksen, Kim, et al.. (2011). Generation of Human Osteoclasts from Peripheral Blood. Methods in molecular biology. 816. 159–175. 33 indexed citations

Coxon, Fraser P., Adam Taylor, Rudi Baron, et al.. (2011). The gunmetal mouse reveals Rab geranylgeranyl transferase to be the major molecular target of phosphonocarboxylate analogues of bisphosphonates. Bone. 49(1). 111–121. 7 indexed citations

Taylor, Adam, Emilie H. Mules, Miguel C. Seabra, et al.. (2011). Impaired prenylation of Rab GTPases in the gunmetal mouse causes defects in bone cell function. Small GTPases. 2(3). 131–142. 23 indexed citations

Błażewska, K. M., Feng Ni, Ralf Haiges, et al.. (2011). Synthesis, stereochemistry and SAR of a series of minodronate analogues as RGGT inhibitors. European Journal of Medicinal Chemistry. 46(10). 4820–4826. 24 indexed citations

10.

Rogers, Michael J., Julie C. Crockett, Fraser P. Coxon, & Jukka Mönkkönen. (2010). Biochemical and molecular mechanisms of action of bisphosphonates. Bone. 49(1). 34–41. 400 indexed citations

11.

Baron, Rudi, Richard Tavaré, Ana C. Figueiredo, et al.. (2008). Phosphonocarboxylates Inhibit the Second Geranylgeranyl Addition by Rab Geranylgeranyl Transferase. Journal of Biological Chemistry. 284(11). 6861–6868. 46 indexed citations

12.

Coxon, Fraser P., Keith Thompson, Anke J. Roelofs, Frank H. Ebetino, & Michael J. Rogers. (2008). Visualizing mineral binding and uptake of bisphosphonate by osteoclasts and non-resorbing cells. Bone. 42(5). 848–860. 190 indexed citations

13.

Taylor, Adam, et al.. (2007). A Novel Method for Efficient Generation of Transfected Human Osteoclasts. Calcified Tissue International. 80(2). 132–136. 19 indexed citations

14.

Wesenbeeck, Liesbeth Van, Paul R. Odgren, Fraser P. Coxon, et al.. (2007). Involvement of PLEKHM1 in osteoclastic vesicular transport and osteopetrosis in incisors absent rats and humans. Journal of Clinical Investigation. 117(4). 919–930. 163 indexed citations

15.

Coxon, Fraser P., Frank H. Ebetino, Emilie H. Mules, et al.. (2005). Phosphonocarboxylate inhibitors of Rab geranylgeranyl transferase disrupt the prenylation and membrane localization of Rab proteins in osteoclasts in vitro and in vivo. Bone. 37(3). 349–358. 86 indexed citations

16.

Twelves, C.J., J McKendrick, Oscar Bertetto, et al.. (2004). Pharmacoeconomic analysis of Capecitabine in the adjuvant setting. Results from the X-ACT trial comparing capecitabine with 5-FU/LV in patients with Dukes' C colon cancer. Annals of Oncology. 15. 73–73. 7 indexed citations

17.

Coxon, Fraser P. & Michael J. Rogers. (2003). The Role of Prenylated Small GTP-Binding Proteins in the Regulation of Osteoclast Function. Calcified Tissue International. 72(1). 80–84. 72 indexed citations

18.

Coxon, Fraser P., Miep Helfrich, Banafshé Larijani, et al.. (2001). Identification of a Novel Phosphonocarboxylate Inhibitor of Rab Geranylgeranyl Transferase That Specifically Prevents Rab Prenylation in Osteoclasts and Macrophages. Journal of Biological Chemistry. 276(51). 48213–48222. 136 indexed citations

19.

Rogers, Michael J., Sharon Gordon, Helena L. Benford, et al.. (2000). Cellular and molecular mechanisms of action of bisphosphonates. Cancer. 88(S12). 2961–2978. 720 indexed citations breakdown →

20.

Rogers, Michael J., Julie C. Frith, Steven P. Luckman, et al.. (1999). Molecular mechanisms of action of bisphosphonates. Bone. 24(5). 73S–79S. 181 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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