Frank Maley

12.4k citations

219 papers · 10.6k indexed · 3 hit papers · h-index 54

Biotechnology top 0.1%
- Enzyme Production and Characterization 26
Molecular Biology top 0.5%
- Biochemical and Molecular Research 84
- Glycosylation and Glycoproteins Research 33
- RNA and protein synthesis mechanisms 18
Nutrition and Dietetics top 0.5%
- Microbial Metabolites in Food Biotechnology 23
Oncology top 2%
- Colorectal Cancer Treatments and Studies 25
Organic Chemistry top 1%
- Carbohydrate Chemistry and Synthesis 32
Materials Chemistry
- Enzyme Structure and Function 53

Co-authors: Gladys F. Maley Anthony L. Tarentino Robert B. Trimble Thomas H. Plummer Frederick K. Chu Marlene Belfort John Galivan Joan Pedersen-Lane
Cited by: Biotechnology Molecular Biology Nutrition and Dietetics
Journals: Journal of Biological Chemistry (75 papers)Biochemistry (26 papers)Archives of Biochemistry and Biophysics (15 papers)
Partner nations: United States Mexico Ukraine

In The Last Decade

Frank Maley

218 papers receiving 9.7k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

1989 Analytical Biochemistry
1974 Journal of Biological Chemistry
1974 Journal of Biological Chemistry

Peers

Countries citing papers authored by Frank Maley

Since Specialization

Citations

This map shows the geographic impact of Frank Maley's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank Maley with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank Maley more than expected).

Fields of papers citing papers by Frank Maley

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank Maley. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank Maley. The network helps show where Frank Maley may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Frank Maley, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Frank Maley Line = papers co-authored together Frank Maley links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Role of an invariant lysine residue in folate binding on Escherichia coli thymidylate synthase: Calorimetric and crystallographic analysis of the K48Q mutant The International Journal of Biochemistry & Cell Biology ·Aldo A. Arvizu‐Flores,Muazam Nugroho,Rodrigo Arreola,Karina D. García‐Orozco,Enrique F. Velázquez-Contreras,W.R. Montfort,Frank Maley,Rogerio R. Sotelo‐Mundo	2008	10
2	Extracting dust from soil: A simple solution to a tricky task The Science of The Total Environment ·Karin Ljung,Madeleine Ekstrand,Michael Smirk,Frank Maley,Angus Cook,Philip Weinstein	2008	22
3	Crystal structures of thymidylate synthase mutant R166Q: Structural basis for the nearly complete loss of catalytic activity Journal of Biochemical and Molecular Toxicology ·Rogerio R. Sotelo‐Mundo,Li‐Ming Changchien,Frank Maley,W.R. Montfort	2006	9
4	Protection of hematopoietic stem cells from pemetrexed toxicity by retroviral gene transfer with a mutant dihydrofolate reductase-mutant thymidylate synthase fusion gene Cancer Gene Therapy ·Iro Koletsou,Tülin Budak-Alpdoǧan,Önder Alpdoğan,William G. Bornmann,Naoko Takebe,Debabrata Banerjee,Frank Maley,Joseph R. Bertino	2004	12
5	Thymidylate synthase protein expression in colorectalcancer metastases predicts for clinical outcome to leucovorin-modulated bolus or infusional 5-fluorouracil but not methotrexate-modulated bolus 5-fluorouracil Annals of Oncology ·C. Aschele,Domizia Debernardis,Roberto Bandelloni,Stefano Cascinu,Vincenzo Catalano,Paolo Giordani,Sandro Barni,D. Turci,芳香本田,Sara Lonardi,紀井俊輝,Frank Maley,S. Monfardini	2002	36
6	Crystal structure of a deletion mutant of human thymidylate synthase Δ (7–29) and its ternary complex with Tomudex and dUMP Protein Science ·Мирослав Беззуб’як,C.A. Waddling,Frank Maley,Gladys F. Maley,Patrick Van Roey	2001	58
7	High-Level Expression of Escherichia coli and Bacillus subtilis Thymidylate Synthases Protein Expression and Purification ·Li‐Ming Changchien,Jin-Peng Zang,Verna Frasca,Jean-Charles Vereerstraeten,Gladys F. Maley,Frank Maley	2000	24
8	Thymidylate Synthase Protein and p53 mRNA Form an In Vivo Ribonucleoprotein Complex Molecular and Cellular Biology ·Edward Chu,Sitki Copur,Jingfang Ju,Purva Bankar,Samir N. Khleif,Donna Voeller,Nobuyuki Mizunuma,Mahendra Patel,Gladys F. Maley,Frank Maley,Carmen J. Allegra	1999	80
9	Intracellular Location of Thymidylate Synthase and Its State of Phosphorylation Journal of Biological Chemistry ·William A. Samsonoff,James Reston,Mary McKee,Brigid M. O'Connor,John Galivan,Gladys F. Maley,Frank Maley	1997	42
10	Complete Restoration of Activity to Inactive Mutants of Escherichia coli Thymidylate Synthase: Evidence that E. coli Thymidylate Synthase is a Half-the-Sites Activity Enzyme Biochemistry ·Frank Maley,Joan Pedersen-Lane,Li‐Ming Changchien	1995	49
11	Identification of a thymidylate synthase ribonucleoprotein complex in human colon cancer cells Molecular and Cellular Biology ·Edward Chu,Donna Voeller,Kristen L. Jones,Teiji Takechi,Gladys F. Maley,Frank Maley,Shoshana Segal,Carmen J. Allegra	1994	18
12	Overcoming Inclusion Body Formation in a High-Level Expression System Protein Expression and Purification ·John T. Moore,Urvish Trivedi,Frank Maley,Gladys F. Maley	1993	86
13	Catalytically active cross-species heterodimers of thymidylate synthase Biochemistry ·Patricia J. Greene,Frank Maley,Joan Pedersen-Lane,Daniel V. Santi	1993	11
14	Plastic adaptation toward mutations in proteins: Structural comparison of thymidylate synthases Proteins Structure Function and Bioinformatics ·Kathy M. Perry,Eric B. Fauman,Janet Finer-Moore,W.R. Montfort,Gladys F. Maley,Frank Maley,Robert M. Stroud	1990	128
15	Intron‐associated splicing reactions in bacteriophage T4 Molecular Microbiology ·Frank Maley,Frederick K. Chu,Gladys F. Maley	1990	0
16	Effect of oligosaccharides and chloride on the oligomeric structures of external, internal, and deglycosylated invertase Biochemistry ·Elif Karasu,Robert MacColl,Frank Maley	1990	34
17	A Tale of Two Enzymes, Deoxycytidylate Deaminase and Thymidylate Synthase Progress in nucleic acid research and molecular biology ·Frank Maley,Gladys F. Maley	1990	29
18	Characterization of glycoproteins and their associated oligosaccharides through the use of endoglycosidasesbreakdown → Analytical Biochemistry ·Frank Maley,Robert B. Trimble,Anthony L. Tarentino,Thomas H. Plummer	1989	654
19	Localization of the T4 phage ribonucleotide reductase B1 subunit gene and the nucleotide sequence of its upstream and 5' coding regions Gene ·Frederick K. Chu,Gladys F. Maley,Aimin Wang,Frank Maley	1987	1
20	[56] Endo-β-N-acetylglucosaminidase L from Streptomyces plicatus Methods in enzymology on CD-ROM/Methods in enzymology ·Robert B. Trimble,Anthony L. Tarentino,Betsy Leondar-Wright,Frank Maley	1982	6

About Frank Maley

Frank Maley is a scholar working on Biotechnology, Molecular Biology and Biochemistry, having authored 219 papers that have together received 10.6k indexed citations. Recurring topics across this work include Biochemical and Molecular Research (84 papers), Enzyme Structure and Function (53 papers), Glycosylation and Glycoproteins Research (33 papers), Carbohydrate Chemistry and Synthesis (32 papers), Enzyme Production and Characterization (26 papers), Colorectal Cancer Treatments and Studies (25 papers), Microbial Metabolites in Food Biotechnology (23 papers) and RNA and protein synthesis mechanisms (18 papers). The work is most often cited by research in Biotechnology (1.4k citations), Molecular Biology (8.0k citations) and Nutrition and Dietetics (1.1k citations). Frank Maley has collaborated with scholars based in United States, Mexico and Ukraine. Frequent co-authors include Gladys F. Maley, Anthony L. Tarentino, Robert B. Trimble, Thomas H. Plummer, Frederick K. Chu, Marlene Belfort, John Galivan, Joan Pedersen-Lane, Edward Chu and W.R. Montfort. Their work appears in journals such as Journal of Biological Chemistry, Biochemistry, Archives of Biochemistry and Biophysics, Proceedings of the National Academy of Sciences and Biochemical and Biophysical Research Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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